Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.007 0.084 0.227 67.0 -9999.0 0.0 67.0 KIRREL 0.02 0.032 -9999.0 0.0 -0.382 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.007 0.085 -9999.0 0.0 -0.227 67.0 67.0 PLCG1 0.023 0.01 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.033 0.072 -9999.0 0.0 -0.224 4.0 4.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.009 0.039 -9999.0 0.0 -0.225 4.0 4.0 FYN 0.002 0.069 0.196 31.0 -0.206 5.0 36.0 mol:Ca2+ 0.028 0.069 -9999.0 0.0 -0.215 5.0 5.0 mol:DAG 0.029 0.07 -9999.0 0.0 -0.216 5.0 5.0 NPHS2 0.011 0.032 -9999.0 0.0 -0.337 2.0 2.0 mol:IP3 0.029 0.07 -9999.0 0.0 -0.216 5.0 5.0 regulation of endocytosis 0.027 0.061 -9999.0 0.0 -0.207 3.0 3.0 Nephrin/NEPH1/podocin/Cholesterol 0.021 0.068 -9999.0 0.0 -0.163 66.0 66.0 establishment of cell polarity 0.007 0.084 -9999.0 0.0 -0.227 67.0 67.0 Nephrin/NEPH1/podocin/NCK1-2 0.042 0.073 -9999.0 0.0 -0.278 1.0 1.0 Nephrin/NEPH1/beta Arrestin2 0.029 0.062 -9999.0 0.0 -0.209 3.0 3.0 NPHS1 -0.018 0.11 -9999.0 0.0 -0.322 67.0 67.0 Nephrin/NEPH1/podocin 0.024 0.061 0.184 1.0 -0.199 6.0 7.0 TJP1 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.03 0.07 -9999.0 0.0 -0.217 5.0 5.0 CD2AP 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.033 0.075 -9999.0 0.0 -0.214 6.0 6.0 GRB2 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.008 0.071 0.206 29.0 -0.207 4.0 33.0 cytoskeleton organization 0.001 0.051 0.203 11.0 -0.234 5.0 16.0 Nephrin/NEPH1 0.011 0.059 -9999.0 0.0 -0.15 67.0 67.0 Nephrin/NEPH1/ZO-1 0.024 0.073 -9999.0 0.0 -0.178 62.0 62.0