Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
FAM18B2	26 (18%)	121	0.16218	0.837	0.35992	0.987	0.7177	1	0.5324	1	0.64611	1	0.49718	1	0.29967	0.964	0.44678	1	0.70042	1	0.67046	1
KIT	26 (18%)	121	0.00444	0.131	9.9999e-06	0.000656	3e-05	0.00147	9.9999e-06	0.000656	9.9999e-06	0.000656	9.9999e-06	0.000656	9.9999e-06	0.000656	9.9999e-06	0.000656	9.9999e-06	0.000656	9.9999e-06	0.000656
KRAS	19 (13%)	128	0.00135	0.0469	0.01026	0.224	0.00392	0.122	0.00033	0.015	0.00038	0.016	0.00185	0.0606	9.9999e-06	0.000656	3e-05	0.00147	2e-05	0.00118	0.00061999	0.0229
FAM104B	7 (5%)	140	0.082729	0.634	0.47537	1	0.24806	0.947	0.71876	1	0.093429	0.656	0.26326	0.947	0.096529	0.664	0.25303	0.947	0.53891	1	0.57824	1
CSGALNACT2	5 (3%)	142	0.04931	0.52	0.18194	0.848	0.04489	0.52	0.02236	0.366	0.00056999	0.0224	0.01106	0.233	0.03357	0.44	0.0161	0.317	0.0245	0.371	0.04176	0.503
NRAS	7 (5%)	140	0.067979	0.59	0.29738	0.964	0.15559	0.82	0.03527	0.445	0.02324	0.371	0.14434	0.789	0.098759	0.664	0.01682	0.32	0.071319	0.604	0.17192	0.848
DDX11	8 (5%)	139	0.91378	1	0.68522	1	0.58933	1	0.1433	0.789	0.56133	1	0.3621	0.987	0.13303	0.777	0.28989	0.95	0.65312	1	0.28431	0.948
MUC6	15 (10%)	132	0.95611	1	0.44248	1	0.59023	1	0.071639	0.604	0.98702	1	0.96506	1	1	1	0.73302	1	0.77691	1	0.73205	1
PNPLA4	5 (3%)	142	0.6646	1	0.56209	1	0.44058	1	0.71737	1	0.49923	1	0.55383	1	0.37818	0.987	0.44636	1	0.32034	0.987	0.77585	1
SERINC2	4 (3%)	143	1	1	0.74418	1	0.16316	0.837	0.052969	0.524	0.77527	1	0.73831	1	1	1	0.58609	1	0.81252	1	0.27315	0.947
RHPN2	6 (4%)	141	0.81303	1	0.79908	1	0.78019	1	1	1	0.96384	1	0.92283	1	0.57809	1	1	1	1	1	0.87958	1
RBM10	5 (3%)	142	0.42795	1	0.26735	0.947	0.87857	1	0.71776	1	0.20659	0.891	0.71055	1	0.63062	1	0.59742	1	0.60601	1	0.27739	0.947
HSF4	6 (4%)	141	0.16946	0.848	0.10708	0.685	0.49918	1	1	1	0.69619	1	0.14128	0.786	0.20508	0.891	0.3677	0.987	0.27713	0.947	0.59407	1
CDC27	6 (4%)	141	0.01185	0.241	0.44233	1	0.21033	0.893	0.184	0.848	0.058279	0.536	0.057509	0.536	0.32408	0.987	0.13876	0.786	0.16792	0.848	0.28188	0.947
MLLT3	4 (3%)	143	0.46204	1	0.7444	1	NA	NA	NA	NA	0.7347	1	0.28251	0.947	1	1	0.58547	1	0.46705	1	0.71788	1
ERC1	7 (5%)	140	0.36588	0.987	0.86446	1	0.90858	1	0.86177	1	0.8657	1	0.56052	1	1	1	1	1	1	1	0.67707	1
MEF2A	3 (2%)	144	1	1	0.75806	1	NA	NA	NA	NA	0.76635	1	0.32847	0.987	1	1	1	1	1	1	0.31415	0.987
SP8	6 (4%)	141	0.03544	0.445	0.34136	0.987	0.076539	0.608	0.02162	0.366	0.22778	0.93	0.0062599	0.161	0.04868	0.52	0.02173	0.366	0.02428	0.371	0.10023	0.664
NAT10	4 (3%)	143	0.33035	0.987	0.82189	1	0.86475	1	0.5954	1	0.59217	1	0.25866	0.947	0.83327	1	1	1	1	1	0.65082	1
SPIN2A	3 (2%)	144	0.59995	1	0.50762	1	NA	NA	NA	NA	0.50371	1	0.3718	0.987	1	1	1	1	1	1	0.78349	1
DEK	5 (3%)	142	0.063279	0.566	0.01974	0.353	0.43855	1	0.27608	0.947	0.084219	0.634	0.01815	0.335	0.37628	0.987	0.31853	0.987	0.44403	1	0.078419	0.609
FANK1	4 (3%)	143	0.17603	0.848	0.74316	1	0.23983	0.943	0.60022	1	0.45699	1	0.7083	1	0.45706	1	0.28159	0.947	0.27206	0.947	0.43352	1
ANKRD11	7 (5%)	140	0.85055	1	0.28263	0.947	0.59329	1	0.65026	1	0.03739	0.46	0.85146	1	0.33324	0.987	0.28685	0.95	0.27831	0.947	0.66512	1
C22ORF43	3 (2%)	144	0.0472	0.52	0.50718	1	0.051249	0.521	0.79549	1	0.84893	1	0.73637	1	1	1	1	1	1	1	0.71273	1
ATXN3	3 (2%)	144	0.71693	1	1	1	0.21241	0.895	0.099569	0.664	0.42798	1	0.18089	0.848	0.49941	1	0.091479	0.656	0.092869	0.656	0.33259	0.987
TPTE2	5 (3%)	142	0.71633	1	0.5232	1	1	1	1	1	0.43864	1	0.63344	1	0.04921	0.52	0.38166	0.987	0.44203	1	0.90666	1
KRTAP10-10	5 (3%)	142	1	1	0.4572	1	0.76058	1	0.53468	1	0.47077	1	0.87229	1	0.15832	0.827	0.59592	1	0.60318	1	0.17677	0.848
ZNF680	3 (2%)	144	0.18506	0.848	0.6712	1	0.51572	1	0.2318	0.93	0.61934	1	0.85726	1	0.058619	0.536	0.34139	0.987	0.33074	0.987	0.81616	1
RAC1	4 (3%)	143	0.70217	1	0.90303	1	0.64429	1	1	1	0.27038	0.947	0.63788	1	0.25418	0.947	0.48113	1	0.36684	0.987	0.17739	0.848
NBPF10	7 (5%)	140	0.23047	0.93	0.78887	1	0.78449	1	1	1	0.23192	0.93	0.23319	0.93	0.55518	1	0.41685	1	0.42092	1	0.28105	0.947
FAM8A1	3 (2%)	144	0.44353	1	0.75896	1	NA	NA	NA	NA	0.077319	0.608	0.51736	1	0.057899	0.536	0.34417	0.987	0.33252	0.987	0.10324	0.677
PSMD11	4 (3%)	143	0.084849	0.634	0.076679	0.608	0.29631	0.964	0.23205	0.93	0.45798	1	0.7543	1	0.55769	1	0.19579	0.863	0.36481	0.987	0.69828	1
KRTAP1-1	3 (2%)	144	1	1	0.44443	1	NA	NA	NA	NA	1	1	0.47353	1	0.77547	1	0.61705	1	0.60944	1	0.41288	1
OPLAH	4 (3%)	143	0.25548	0.947	0.35333	0.987	0.5733	1	0.79696	1	1	1	0.31352	0.987	0.55701	1	0.28001	0.947	1	1	0.85777	1
FAM101B	4 (3%)	143	1	1	1	1	1	1	1	1	0.62722	1	0.49619	1	1	1	1	1	1	1	1	1
MUC2	16 (11%)	131	0.51752	1	0.91671	1	0.56639	1	0.42982	1	0.34027	0.987	0.98411	1	0.49863	1	0.94325	1	0.79066	1	0.51337	1
HTT	3 (2%)	144	1	1	0.38324	0.987	NA	NA	NA	NA	1	1	0.68052	1	0.63057	1	0.61439	1	0.60751	1	0.93851	1
EZH2	4 (3%)	143	0.88368	1	0.25589	0.947	NA	NA	NA	NA	0.56252	1	0.54505	1	0.55697	1	0.28029	0.947	0.27401	0.947	0.37492	0.987
PABPC3	4 (3%)	143	0.88557	1	0.51572	1	NA	NA	NA	NA	0.23555	0.933	0.60797	1	0.19474	0.863	0.38171	0.987	0.57635	1	0.36136	0.987
CUX1	5 (3%)	142	0.90799	1	1	1	0.86376	1	0.59597	1	0.46854	1	0.96358	1	0.63075	1	0.85388	1	0.85657	1	0.85847	1
DLC1	3 (2%)	144	0.44483	1	1	1	0.64068	1	1	1	1	1	0.94888	1	0.62997	1	0.61796	1	0.60862	1	0.93889	1
STAB1	7 (5%)	140	0.71972	1	0.1408	0.786	0.35687	0.987	1	1	0.45422	1	0.49973	1	0.23235	0.93	0.19595	0.863	0.12352	0.729	0.61763	1
NOTCH1	5 (3%)	142	0.71985	1	0.86282	1	0.21904	0.917	0.84356	1	0.11423	0.702	0.44769	1	0.37663	0.987	0.31859	0.987	0.20903	0.893	0.75258	1
AHDC1	4 (3%)	143	0.78321	1	0.050939	0.521	0.03334	0.44	0.10801	0.685	0.074129	0.607	0.02586	0.379	0.0052399	0.147	0.0093499	0.221	0.01018	0.224	0.0072199	0.177
EPAS1	5 (3%)	142	0.61388	1	1	1	0.83146	1	0.67991	1	0.4842	1	0.78915	1	0.63069	1	0.85482	1	0.8598	1	0.52069	1
PIK3CD	4 (3%)	143	0.04774	0.52	0.35296	0.987	NA	NA	NA	NA	0.1854	0.848	0.37184	0.987	0.14074	0.786	0.69617	1	0.69017	1	0.25567	0.947
BCL11B	5 (3%)	142	0.098519	0.664	0.60246	1	0.52702	1	0.53498	1	0.43617	1	0.93601	1	0.52842	1	0.38274	0.987	0.44411	1	0.71893	1
KIAA0430	3 (2%)	144	0.44175	1	0.10712	0.685	NA	NA	NA	NA	0.6882	1	0.77348	1	0.63116	1	0.61613	1	0.60551	1	0.94051	1
MTIF3	3 (2%)	144	1	1	0.85881	1	1	1	1	1	0.84777	1	1	1	0.37788	0.987	0.79566	1	0.79582	1	1	1
BTN2A2	3 (2%)	144	0.44644	1	0.75576	1	NA	NA	NA	NA	0.1794	0.848	0.81206	1	0.37339	0.987	0.7957	1	0.79451	1	0.64628	1
C17ORF64	3 (2%)	144	0.84286	1	0.85754	1	NA	NA	NA	NA	0.85019	1	0.37021	0.987	1	1	1	1	0.45252	1	0.55849	1
RUNX2	4 (3%)	143	0.32868	0.987	1	1	0.86387	1	0.60043	1	1	1	1	1	0.83041	1	1	1	1	1	0.65215	1
SSBP3	3 (2%)	144	0.84338	1	1	1	NA	NA	NA	NA	0.38489	0.987	0.059089	0.536	0.49735	1	0.092809	0.656	0.092929	0.656	0.072769	0.605
GSX2	4 (3%)	143	0.15176	0.811	0.46816	1	0.64721	1	0.02726	0.379	0.053309	0.524	0.24284	0.947	0.065619	0.578	0.14974	0.811	0.81123	1	0.56137	1
SP4	4 (3%)	143	0.1526	0.811	0.12145	0.724	NA	NA	NA	NA	0.1715	0.848	0.11189	0.695	0.31637	0.987	0.02754	0.379	0.0276	0.379	0.1176	0.713
PCMTD1	5 (3%)	142	0.1747	0.848	0.11839	0.713	0.45349	1	0.53577	1	0.52331	1	0.44424	1	0.37764	0.987	0.31802	0.987	0.20685	0.891	0.55138	1
RBM3	3 (2%)	144	0.0062899	0.161	0.38373	0.987	NA	NA	NA	NA	1	1	0.9478	1	0.11175	0.695	0.61522	1	0.60661	1	0.41206	1
ZNF814	5 (3%)	142	0.13498	0.781	0.4288	1	0.93255	1	0.8412	1	0.30067	0.964	0.25795	0.947	0.73389	1	1	1	1	1	0.4523	1
TTC38	4 (3%)	143	0.28848	0.95	0.51408	1	0.91532	1	0.19388	0.863	0.43476	1	0.81902	1	0.19487	0.863	0.38065	0.987	0.57892	1	0.04542	0.52