Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.101 0.247 0.533 115.0 -9999.0 0.0 115.0 KIRREL -0.046 0.197 -9999.0 0.0 -0.693 41.0 41.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.101 0.247 -9999.0 0.0 -0.544 111.0 111.0 PLCG1 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.057 0.206 -9999.0 0.0 -0.436 105.0 105.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.058 0.159 -9999.0 0.0 -0.352 103.0 103.0 FYN -0.063 0.198 0.276 26.0 -0.41 105.0 131.0 mol:Ca2+ -0.056 0.201 -9999.0 0.0 -0.431 104.0 104.0 mol:DAG -0.056 0.203 -9999.0 0.0 -0.433 104.0 104.0 NPHS2 -0.005 0.054 -9999.0 0.0 -0.739 1.0 1.0 mol:IP3 -0.056 0.203 -9999.0 0.0 -0.433 104.0 104.0 regulation of endocytosis -0.05 0.181 -9999.0 0.0 -0.387 103.0 103.0 Nephrin/NEPH1/podocin/Cholesterol -0.068 0.199 -9999.0 0.0 -0.434 106.0 106.0 establishment of cell polarity -0.101 0.247 -9999.0 0.0 -0.533 115.0 115.0 Nephrin/NEPH1/podocin/NCK1-2 -0.04 0.197 -9999.0 0.0 -0.403 105.0 105.0 Nephrin/NEPH1/beta Arrestin2 -0.05 0.184 -9999.0 0.0 -0.392 103.0 103.0 NPHS1 -0.103 0.261 -9999.0 0.0 -0.675 84.0 84.0 Nephrin/NEPH1/podocin -0.061 0.191 -9999.0 0.0 -0.411 106.0 106.0 TJP1 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.055 0.204 -9999.0 0.0 -0.435 104.0 104.0 CD2AP 0.027 0.003 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.055 0.203 -9999.0 0.0 -0.435 102.0 102.0 GRB2 0.026 0.007 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.078 0.197 0.277 21.0 -0.414 107.0 128.0 cytoskeleton organization -0.082 0.2 -9999.0 0.0 -0.453 102.0 102.0 Nephrin/NEPH1 -0.072 0.186 -9999.0 0.0 -0.406 109.0 109.0 Nephrin/NEPH1/ZO-1 -0.069 0.213 -9999.0 0.0 -0.459 106.0 106.0