Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.087 0.186 0.368 36.0 -9999.0 0.0 36.0 KIRREL -0.123 0.238 -9999.0 0.0 -0.507 33.0 33.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.087 0.187 -9999.0 0.0 -0.368 36.0 36.0 PLCG1 0.032 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.03 0.009 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.03 0.009 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.046 0.155 -9999.0 0.0 -0.277 36.0 36.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.059 0.129 -9999.0 0.0 -0.252 35.0 35.0 FYN -0.05 0.158 0.297 8.0 -0.262 36.0 44.0 mol:Ca2+ -0.045 0.154 -9999.0 0.0 -0.275 36.0 36.0 mol:DAG -0.045 0.155 -9999.0 0.0 -0.276 36.0 36.0 NPHS2 -0.009 0.039 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.045 0.155 -9999.0 0.0 -0.276 36.0 36.0 regulation of endocytosis -0.042 0.138 -9999.0 0.0 -0.248 36.0 36.0 Nephrin/NEPH1/podocin/Cholesterol -0.056 0.146 -9999.0 0.0 -0.275 36.0 36.0 establishment of cell polarity -0.087 0.186 -9999.0 0.0 -0.368 36.0 36.0 Nephrin/NEPH1/podocin/NCK1-2 -0.033 0.156 -9999.0 0.0 -0.264 35.0 35.0 Nephrin/NEPH1/beta Arrestin2 -0.042 0.141 -9999.0 0.0 -0.251 36.0 36.0 NPHS1 -0.013 0.111 -9999.0 0.0 -0.454 6.0 6.0 Nephrin/NEPH1/podocin -0.052 0.141 -9999.0 0.0 -0.263 36.0 36.0 TJP1 0.032 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.027 0.049 -9999.0 0.0 -0.5 1.0 1.0 NCK2 0.033 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.044 0.156 -9999.0 0.0 -0.277 36.0 36.0 CD2AP 0.03 0.01 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.044 0.154 -9999.0 0.0 -0.277 35.0 35.0 GRB2 0.03 0.009 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.054 0.153 0.329 6.0 -0.255 37.0 43.0 cytoskeleton organization -0.074 0.144 -9999.0 0.0 -0.291 35.0 35.0 Nephrin/NEPH1 -0.058 0.132 -9999.0 0.0 -0.257 36.0 36.0 Nephrin/NEPH1/ZO-1 -0.057 0.159 -9999.0 0.0 -0.295 36.0 36.0