Aurora B signaling Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations Condensin I complex -0.014 0.155 -9999.0 0.0 -0.485 10.0 10.0 STMN1 -0.013 0.116 -9999.0 0.0 -0.409 9.0 9.0 Aurora B/RasGAP/Survivin 0.017 0.16 -9999.0 0.0 -0.454 11.0 11.0 Chromosomal passenger complex/Cul3 protein complex -0.007 0.127 -9999.0 0.0 -0.447 8.0 8.0 BIRC5 -0.003 0.132 -9999.0 0.0 -0.527 7.0 7.0 DES -0.452 0.387 -9999.0 0.0 -0.648 85.0 85.0 Aurora C/Aurora B/INCENP 0.039 0.091 -9999.0 0.0 -0.284 8.0 8.0 Aurora B/TACC1 0.018 0.091 -9999.0 0.0 -0.31 8.0 8.0 Aurora B/PP2A 0.02 0.105 -9999.0 0.0 -0.364 8.0 8.0 mol:GTP -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CBX5 0.002 0.042 -9999.0 0.0 -0.153 8.0 8.0 mitotic metaphase/anaphase transition -0.0 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NDC80 -0.01 0.112 -9999.0 0.0 -0.414 8.0 8.0 Cul3 protein complex 0.06 0.024 -9999.0 0.0 -9999.0 0.0 0.0 KIF2C -0.001 0.11 -9999.0 0.0 -0.347 7.0 7.0 PEBP1 0.029 0.015 -9999.0 0.0 -9999.0 0.0 0.0 KIF20A 0.023 0.069 -9999.0 0.0 -0.503 2.0 2.0 mol:GDP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Aurora B/RasGAP 0.012 0.118 -9999.0 0.0 -0.368 10.0 10.0 SEPT1 -0.022 0.16 -9999.0 0.0 -0.5 12.0 12.0 SMC2 0.032 0.007 -9999.0 0.0 -9999.0 0.0 0.0 SMC4 0.032 0.007 -9999.0 0.0 -9999.0 0.0 0.0 NSUN2/NPM1/Nucleolin -0.074 0.249 -9999.0 0.0 -0.622 19.0 19.0 PSMA3 0.031 0.007 -9999.0 0.0 -9999.0 0.0 0.0 G2/M transition of mitotic cell cycle 0.0 0.004 -9999.0 0.0 -9999.0 0.0 0.0 H3F3B -0.003 0.086 -9999.0 0.0 -0.323 8.0 8.0 AURKB 0.001 0.139 -9999.0 0.0 -0.516 8.0 8.0 AURKC 0.027 0.012 -9999.0 0.0 -9999.0 0.0 0.0 CDCA8 0.021 0.074 -9999.0 0.0 -0.53 2.0 2.0 cytokinesis -0.069 0.24 -9999.0 0.0 -0.792 10.0 10.0 Aurora B/Septin1 -0.042 0.266 -9999.0 0.0 -0.707 13.0 13.0 AURKA 0.033 0.008 -9999.0 0.0 -9999.0 0.0 0.0 INCENP 0.03 0.017 -9999.0 0.0 -9999.0 0.0 0.0 KLHL13 0.028 0.049 -9999.0 0.0 -0.5 1.0 1.0 BUB1 0.015 0.097 -9999.0 0.0 -0.507 4.0 4.0 hSgo1/Aurora B/Survivin 0.012 0.179 -9999.0 0.0 -0.578 9.0 9.0 EVI5 0.033 0.007 -9999.0 0.0 -9999.0 0.0 0.0 RhoA/GTP 0.011 0.201 -9999.0 0.0 -0.623 9.0 9.0 SGOL1 0.013 0.096 -9999.0 0.0 -0.5 4.0 4.0 CENPA -0.04 0.211 -9999.0 0.0 -0.641 11.0 11.0 NCAPG 0.001 0.125 -9999.0 0.0 -0.5 7.0 7.0 Aurora B/HC8 Proteasome 0.024 0.1 -9999.0 0.0 -0.364 7.0 7.0 NCAPD2 0.031 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Aurora B/PP1-gamma 0.021 0.106 -9999.0 0.0 -0.368 8.0 8.0 RHOA 0.031 0.008 -9999.0 0.0 -9999.0 0.0 0.0 NCAPH 0.019 0.084 -9999.0 0.0 -0.5 3.0 3.0 NPM1 -0.044 0.172 -9999.0 0.0 -0.44 17.0 17.0 RASA1 0.018 0.084 -9999.0 0.0 -0.5 3.0 3.0 KLHL9 0.031 0.008 -9999.0 0.0 -9999.0 0.0 0.0 mitotic prometaphase -0.001 0.005 -9999.0 0.0 -9999.0 0.0 0.0 proteasomal ubiquitin-dependent protein catabolic process 0.024 0.1 -9999.0 0.0 -0.363 7.0 7.0 PPP1CC 0.032 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Centraspindlin 0.001 0.218 -9999.0 0.0 -0.685 9.0 9.0 RhoA/GDP 0.023 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NSUN2 -0.046 0.173 -9999.0 0.0 -0.44 17.0 17.0 MYLK -0.024 0.112 -9999.0 0.0 -0.318 15.0 15.0 KIF23 0.022 0.071 -9999.0 0.0 -0.515 2.0 2.0 VIM -0.007 0.097 -9999.0 0.0 -0.368 8.0 8.0 RACGAP1 0.031 0.012 -9999.0 0.0 -9999.0 0.0 0.0 mitosis -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCL -0.05 0.192 -9999.0 0.0 -0.472 17.0 17.0 Chromosomal passenger complex -0.024 0.199 -9999.0 0.0 -0.702 8.0 8.0 Chromosomal passenger complex/EVI5 0.072 0.186 -9999.0 0.0 -0.574 8.0 8.0 TACC1 0.031 0.007 -9999.0 0.0 -9999.0 0.0 0.0 PPP2R5D 0.03 0.01 -9999.0 0.0 -9999.0 0.0 0.0 CUL3 0.032 0.005 -9999.0 0.0 -9999.0 0.0 0.0 response to DNA damage stimulus 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0