Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.028 0.103 0.278 78.0 -9999.0 0.0 78.0 KIRREL -0.039 0.137 -9999.0 0.0 -0.414 64.0 64.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.028 0.103 -9999.0 0.0 -0.278 78.0 78.0 PLCG1 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.011 0.076 -9999.0 0.0 -0.204 65.0 65.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.005 0.077 -9999.0 0.0 -0.209 64.0 64.0 FYN -0.013 0.072 -9999.0 0.0 -0.198 65.0 65.0 mol:Ca2+ -0.015 0.074 -9999.0 0.0 -0.202 65.0 65.0 mol:DAG -0.011 0.075 -9999.0 0.0 -0.203 65.0 65.0 NPHS2 -0.004 0.028 -9999.0 0.0 -0.331 3.0 3.0 mol:IP3 -0.011 0.075 -9999.0 0.0 -0.203 65.0 65.0 regulation of endocytosis -0.006 0.068 -9999.0 0.0 -0.18 65.0 65.0 Nephrin/NEPH1/podocin/Cholesterol -0.018 0.076 -9999.0 0.0 -0.21 65.0 65.0 establishment of cell polarity -0.028 0.103 -9999.0 0.0 -0.278 78.0 78.0 Nephrin/NEPH1/podocin/NCK1-2 -0.003 0.072 -9999.0 0.0 -0.334 4.0 4.0 Nephrin/NEPH1/beta Arrestin2 -0.005 0.069 -9999.0 0.0 -0.182 65.0 65.0 NPHS1 -0.006 0.056 -9999.0 0.0 -0.328 15.0 15.0 Nephrin/NEPH1/podocin -0.013 0.072 -9999.0 0.0 -0.199 65.0 65.0 TJP1 0.01 0.018 -9999.0 0.0 -0.41 1.0 1.0 NCK1 0.009 0.025 -9999.0 0.0 -0.41 2.0 2.0 NCK2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.011 0.076 -9999.0 0.0 -0.204 65.0 65.0 CD2AP 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.011 0.076 -9999.0 0.0 -0.204 65.0 65.0 GRB2 0.011 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.027 0.097 -9999.0 0.0 -0.222 95.0 95.0 cytoskeleton organization -0.001 0.08 -9999.0 0.0 -0.223 32.0 32.0 Nephrin/NEPH1 -0.017 0.071 -9999.0 0.0 -0.198 65.0 65.0 Nephrin/NEPH1/ZO-1 -0.014 0.083 -9999.0 0.0 -0.225 64.0 64.0