Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	-0.042	0.154	-9999.0	0.0	-0.537	31.0	31.0
IHH	-0.041	0.21	0.31	58.0	-0.386	123.0	181.0
SHH Np/Cholesterol/GAS1	-0.083	0.103	0.23	1.0	-0.186	261.0	262.0
LRPAP1	0.022	0.004	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	0.083	0.102	0.185	261.0	-0.228	1.0	262.0
SMO/beta Arrestin2	-0.038	0.157	-9999.0	0.0	-0.317	95.0	95.0
SMO	-0.056	0.153	-9999.0	0.0	-0.324	110.0	110.0
AKT1	-0.018	0.124	-9999.0	0.0	-0.481	21.0	21.0
ARRB2	0.021	0.006	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.011	0.065	-9999.0	0.0	-0.35	17.0	17.0
ADRBK1	0.022	0.004	-9999.0	0.0	-9999.0	0.0	0.0
heart looping	-0.054	0.152	-9999.0	0.0	-0.321	110.0	110.0
STIL	-0.01	0.118	0.217	13.0	-0.277	28.0	41.0
DHH N/PTCH2	-0.004	0.099	-9999.0	0.0	-0.257	69.0	69.0
DHH N/PTCH1	-0.042	0.131	-9999.0	0.0	-0.24	130.0	130.0
PIK3CA	0.02	0.018	-9999.0	0.0	-0.35	1.0	1.0
DHH	-0.008	0.102	-9999.0	0.0	-0.35	44.0	44.0
PTHLH	-0.061	0.189	-9999.0	0.0	-0.593	31.0	31.0
determination of left/right symmetry	-0.054	0.152	-9999.0	0.0	-0.321	110.0	110.0
PIK3R1	0.018	0.036	-9999.0	0.0	-0.35	5.0	5.0
skeletal system development	-0.06	0.187	-9999.0	0.0	-0.588	31.0	31.0
IHH N/Hhip	-0.004	0.142	0.219	73.0	-0.229	122.0	195.0
DHH N/Hhip	0.016	0.091	0.208	26.0	-0.244	49.0	75.0
mol:Cholesterol	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.054	0.152	-9999.0	0.0	-0.321	110.0	110.0
pancreas development	0.032	0.068	0.279	28.0	-0.349	5.0	33.0
HHAT	0.017	0.033	-9999.0	0.0	-0.35	4.0	4.0
PI3K	0.027	0.029	-9999.0	0.0	-0.246	5.0	5.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	-0.201	0.181	-9999.0	0.0	-0.35	321.0	321.0
somite specification	-0.054	0.152	-9999.0	0.0	-0.321	110.0	110.0
SHH Np/Cholesterol/PTCH1	-0.022	0.109	0.241	5.0	-0.283	30.0	35.0
SHH Np/Cholesterol/PTCH2	0.015	0.059	0.224	6.0	-0.197	28.0	34.0
SHH Np/Cholesterol/Megalin	0.079	0.094	0.204	173.0	-0.176	6.0	179.0
SHH	0.004	0.058	0.13	64.0	-0.246	6.0	70.0
catabolic process	-0.036	0.125	-9999.0	0.0	-0.249	128.0	128.0
SMO/Vitamin D3	-0.014	0.148	0.301	8.0	-0.262	104.0	112.0
SHH Np/Cholesterol/Hhip	0.03	0.059	0.206	33.0	-0.185	11.0	44.0
LRP2	0.11	0.122	0.28	184.0	-9999.0	0.0	184.0
receptor-mediated endocytosis	-0.008	0.139	0.233	11.0	-0.328	29.0	40.0
SHH Np/Cholesterol/BOC	0.017	0.054	0.224	6.0	-0.193	22.0	28.0
SHH Np/Cholesterol/CDO	0.006	0.069	0.224	6.0	-0.19	47.0	53.0
mesenchymal cell differentiation	-0.03	0.059	0.184	11.0	-0.203	33.0	44.0
mol:Vitamin D3	0.0	0.134	0.293	16.0	-0.287	29.0	45.0
IHH N/PTCH2	-0.021	0.146	0.199	57.0	-0.25	134.0	191.0
CDON	-0.014	0.11	-9999.0	0.0	-0.35	52.0	52.0
IHH N/PTCH1	-0.025	0.146	-9999.0	0.0	-0.252	128.0	128.0
Megalin/LRPAP1	0.09	0.084	0.209	177.0	-9999.0	0.0	177.0
PTCH2	0.002	0.084	-9999.0	0.0	-0.35	29.0	29.0
SHH Np/Cholesterol	0.008	0.022	-9999.0	0.0	-0.184	6.0	6.0
PTCH1	-0.037	0.126	-9999.0	0.0	-0.25	128.0	128.0
HHIP	0.032	0.068	0.279	28.0	-0.35	5.0	33.0