Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.091 0.204 -9999.0 0.0 -0.359 146.0 146.0 MAP3K8 0.01 0.033 -9999.0 0.0 -0.352 3.0 3.0 FOS -0.061 0.163 -9999.0 0.0 -0.466 47.0 47.0 PRKCA -0.012 0.087 -9999.0 0.0 -0.353 31.0 31.0 PTPN7 0.009 0.036 0.264 6.0 -9999.0 0.0 6.0 HRAS 0.021 0.005 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.012 0.087 -9999.0 0.0 -0.353 31.0 31.0 NRAS 0.022 0.002 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.022 0.034 0.217 1.0 -9999.0 0.0 1.0 MAPK3 -0.029 0.135 -9999.0 0.0 -0.657 17.0 17.0 MAP2K1 -0.059 0.152 -9999.0 0.0 -0.4 72.0 72.0 ELK1 0.006 0.027 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.04 0.126 -9999.0 0.0 -0.362 62.0 62.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 165.0 165.0 MAPK1 -0.036 0.142 -9999.0 0.0 -0.55 27.0 27.0 RAF1 -0.041 0.132 -9999.0 0.0 -0.382 60.0 60.0 KRAS 0.022 0.014 0.327 1.0 -9999.0 0.0 1.0