Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.008 0.123 -9999.0 0.0 -0.283 6.0 6.0 MAP3K8 -0.01 0.099 -9999.0 0.0 -0.348 4.0 4.0 FOS -0.003 0.088 -9999.0 0.0 -0.291 1.0 1.0 PRKCA 0.006 0.073 -9999.0 0.0 -0.35 2.0 2.0 PTPN7 0.019 0.017 -9999.0 0.0 -9999.0 0.0 0.0 HRAS 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.002 0.005 -9999.0 0.0 -0.015 7.0 7.0 NRAS 0.026 0.011 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.043 0.023 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.009 0.072 -9999.0 0.0 -0.397 1.0 1.0 MAP2K1 -0.015 0.08 -9999.0 0.0 -0.252 4.0 4.0 ELK1 0.02 0.021 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.003 0.062 -9999.0 0.0 -0.303 2.0 2.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.005 7.0 7.0 MAPK1 0.0 0.094 -9999.0 0.0 -0.41 2.0 2.0 RAF1 0.003 0.048 -9999.0 0.0 -0.325 1.0 1.0 KRAS 0.027 0.004 -9999.0 0.0 -9999.0 0.0 0.0