Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q TP53 51 (89%) 6 0.63114 0.89 0.64483 0.892 0.41778 0.825 0.13782 0.532 1 1 0.51287 0.841 1 1 0.91192 1 0.80142 0.977 1 1 FBXW7 22 (39%) 35 0.088569 0.464 0.77527 0.958 0.070329 0.392 0.16596 0.532 0.53966 0.848 0.10366 0.475 0.50836 0.841 0.93244 1 0.91374 1 0.77424 0.958 PPP2R1A 16 (28%) 41 0.64863 0.892 0.80817 0.977 0.58328 0.862 0.50113 0.841 0.77527 0.958 0.67209 0.911 0.36386 0.792 0.31577 0.772 0.58801 0.862 0.2346 0.662 KRAS 7 (12%) 50 0.14026 0.532 0.00189 0.104 0.61083 0.884 0.20145 0.583 0.03008 0.331 0.0058699 0.204 0.87535 1 0.092759 0.464 0.16933 0.532 0.059189 0.388 PTEN 11 (19%) 46 0.0087699 0.204 0.00121 0.104 0.051459 0.388 0.01816 0.25 0.01112 0.204 0.04466 0.378 0.065339 0.392 0.059989 0.388 0.0092999 0.204 0.01343 0.211 RB1 6 (11%) 51 1 1 0.36848 0.792 0.4706 0.841 0.31292 0.772 0.071249 0.392 0.097729 0.467 0.87134 1 0.86284 1 0.52183 0.841 1 1 ZBTB7B 6 (11%) 51 0.52739 0.841 1 1 0.14399 0.532 0.37451 0.792 1 1 0.91499 1 0.15658 0.532 0.14793 0.532 0.42748 0.825 0.16021 0.532 PIK3R1 6 (11%) 51 0.87143 1 1 1 0.5057 0.841 0.77265 0.958 0.57096 0.862 0.70578 0.935 1 1 0.50081 0.841 0.42328 0.825 0.30493 0.772 ARHGAP35 6 (11%) 51 1 1 0.45788 0.841 0.55087 0.853 0.34384 0.792 0.57221 0.862 0.39833 0.811 0.50243 0.841 0.19175 0.57 0.44498 0.841 0.17421 0.532 PIK3CA 20 (35%) 37 0.38923 0.808 0.1562 0.532 0.71522 0.937 0.29435 0.771 0.27525 0.738 0.36882 0.792 0.02327 0.284 0.33921 0.792 0.17278 0.532 0.26913 0.738 MAMLD1 4 (7%) 53 1 1 0.13682 0.532 0.03962 0.363 0.03596 0.36 0.62623 0.89 0.76927 0.958 0.059269 0.388 0.67906 0.911 0.49326 0.841 0.3557 0.792