name #/Mb Nindiv OK N_SNV N_CCG>CAG F_CCG>CAG AF AF_CCG>CAG AF_nCC>CA AF_CpG>T T-C>G-T C-C>G-T A-C>G-T G-C>G-T T-A>T-T C-A>T-T A-A>T-T G-A>T-T T-C>G-C C-C>G-C A-C>G-C G-C>G-C T-A>T-C C-A>T-C A-A>T-C G-A>T-C T-C>G-A C-C>G-A A-C>G-A G-C>G-A T-A>T-A C-A>T-A A-A>T-A G-A>T-A T-C>G-G C-C>G-G A-C>G-G G-C>G-G T-A>T-G C-A>T-G A-A>T-G G-A>T-G T-C>A-T C-C>A-T A-C>A-T G-C>A-T T-A>C-T C-A>C-T A-A>C-T G-A>C-T T-C>A-C C-C>A-C A-C>A-C G-C>A-C T-A>C-C C-A>C-C A-A>C-C G-A>C-C T-C>A-A C-C>A-A A-C>A-A G-C>A-A T-A>C-A C-A>C-A A-A>C-A G-A>C-A T-C>A-G C-C>A-G A-C>A-G G-C>A-G T-A>C-G C-A>C-G A-A>C-G G-A>C-G T-C>T-T C-C>T-T A-C>T-T G-C>T-T T-A>G-T C-A>G-T A-A>G-T G-A>G-T T-C>T-C C-C>T-C A-C>T-C G-C>T-C T-A>G-C C-A>G-C A-A>G-C G-A>G-C T-C>T-A C-C>T-A A-C>T-A G-C>T-A T-A>G-A C-A>G-A A-A>G-A G-A>G-A T-C>T-G C-C>T-G A-C>T-G G-C>T-G T-A>G-G C-A>G-G A-A>G-G G-A>G-G BRCA-freeze-v5.final_analysis_set.maf # 122 OK 28875 114 0.004 0.192 0.169 0.206 0.210 956 124 69 76 15 46 34 52 352 75 70 56 26 42 18 55 719 75 56 49 11 20 55 50 127 67 41 35 22 80 73 57 253 228 136 299 18 42 19 21 282 180 244 335 19 153 60 99 286 201 188 293 19 38 31 40 112 114 82 141 19 128 73 70 1943 2084 240 514 59 135 78 71 2740 1937 486 647 94 103 89 61 2587 1073 130 201 37 47 65 80 2506 1297 560 787 45 157 121 75 BRCA-freeze-v5.final_analysis_set.maf mutations/Mb 122 OK 28875 114 0.004 0.192 0.169 0.206 0.210 6.72 0.83 0.73 0.58 0.24 0.39 0.38 0.54 2.56 0.65 0.67 0.45 0.40 0.35 0.22 0.63 5.49 0.46 0.49 0.39 0.20 0.18 0.43 0.37 3.08 1.17 1.04 0.77 0.40 0.41 0.54 0.43 1.78 1.53 1.43 2.27 0.29 0.35 0.21 0.22 2.05 1.56 2.33 2.69 0.29 1.29 0.73 1.13 2.18 1.24 1.63 2.34 0.34 0.34 0.24 0.30 2.71 1.99 2.08 3.10 0.34 0.66 0.54 0.52 13.65 14.02 2.53 3.90 0.96 1.13 0.87 0.73 19.96 16.77 4.65 5.19 1.43 0.87 1.08 0.70 19.74 6.63 1.13 1.61 0.66 0.41 0.51 0.59 60.69 22.64 14.22 17.30 0.81 0.80 0.90 0.56 100_DM # 1 OK 158 0 0.000 0.117 NaN 0.153 0.103 12 1 2 1 0 0 0 1 3 0 2 0 0 0 0 0 10 0 0 0 0 0 0 1 6 3 0 1 0 0 0 0 1 1 1 10 0 0 0 1 1 2 2 5 0 0 0 0 3 0 2 4 0 0 0 0 0 0 1 2 0 1 0 0 10 1 0 1 0 1 1 1 4 0 0 3 1 0 0 0 27 1 1 2 0 1 0 0 11 3 3 5 0 1 0 0 100_DM mutations/Mb 1 OK 158 0 0.000 0.117 NaN 0.153 0.103 10.29 0.82 2.57 0.93 0.00 0.00 0.00 1.26 2.67 0.00 2.33 0.00 0.00 0.00 0.00 0.00 9.31 0.00 0.00 0.00 0.00 0.00 0.00 0.90 17.73 6.39 0.00 2.68 0.00 0.00 0.00 0.00 0.86 0.82 1.28 9.26 0.00 0.00 0.00 1.26 0.89 2.11 2.33 4.89 0.00 0.00 0.00 0.00 2.79 0.00 2.12 3.90 0.00 0.00 0.00 0.00 0.00 0.00 3.10 5.36 0.00 0.62 0.00 0.00 8.57 0.82 0.00 0.93 0.00 1.02 1.36 1.26 3.56 0.00 0.00 2.94 1.86 0.00 0.00 0.00 25.14 0.75 1.06 1.95 0.00 1.08 0.00 0.00 32.50 6.39 9.29 13.41 0.00 0.62 0.00 0.00 101_DM # 1 OK 68 1 0.015 0.048 0.076 0.074 0.063 0 0 1 1 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 0 4 0 1 0 0 1 2 5 5 0 1 0 0 2 4 3 4 0 0 0 0 0 1 1 2 0 0 0 0 0 0 0 1 0 1 0 1 0 0 0 1 0 0 0 1 1 0 1 1 0 0 0 0 7 1 2 5 0 1 1 0 101_DM mutations/Mb 1 OK 68 1 0.015 0.048 0.076 0.074 0.063 0.00 0.00 1.28 0.93 0.00 1.02 0.00 0.00 0.00 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.62 0.00 0.00 0.86 0.82 0.00 3.70 0.00 1.02 0.00 0.00 0.89 2.11 5.84 4.89 0.00 1.03 0.00 0.00 1.86 3.02 3.18 3.90 0.00 0.00 0.00 0.00 0.00 2.13 3.10 5.36 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 1.02 0.00 1.26 0.00 0.00 0.00 0.98 0.00 0.00 0.00 1.39 0.93 0.00 1.06 0.98 0.00 0.00 0.00 0.00 20.68 2.13 6.19 13.41 0.00 0.62 0.91 0.00 102_DM # 1 OK 135 2 0.015 0.089 0.033 0.119 0.097 9 0 0 0 0 0 1 0 0 1 1 0 0 0 0 1 3 1 1 1 0 0 1 0 0 0 2 1 0 1 1 1 3 4 2 6 0 0 0 0 1 0 3 6 0 0 0 0 3 3 4 7 1 0 0 0 0 2 3 0 0 1 0 0 2 3 0 3 0 1 1 1 4 0 2 1 1 0 1 0 9 2 2 1 0 0 1 0 2 7 6 7 0 1 0 2 102_DM mutations/Mb 1 OK 135 2 0.015 0.089 0.033 0.119 0.097 7.72 0.00 0.00 0.00 0.00 0.00 1.36 0.00 0.00 1.06 1.17 0.00 0.00 0.00 0.00 1.39 2.79 0.75 1.06 0.98 0.00 0.00 0.96 0.00 0.00 0.00 6.19 2.68 0.00 0.62 0.91 0.91 2.57 3.28 2.57 5.56 0.00 0.00 0.00 0.00 0.89 0.00 3.50 5.87 0.00 0.00 0.00 0.00 2.79 2.26 4.24 6.83 2.17 0.00 0.00 0.00 0.00 4.26 9.29 0.00 0.00 0.62 0.00 0.00 1.71 2.46 0.00 2.78 0.00 1.02 1.36 1.26 3.56 0.00 2.33 0.98 1.86 0.00 1.48 0.00 8.38 1.51 2.12 0.98 0.00 0.00 0.96 0.00 5.91 14.91 18.58 18.78 0.00 0.62 0.00 1.83 103_DM # 1 OK 106 0 0.000 0.118 NaN 0.138 0.162 1 0 0 0 0 0 0 0 1 3 1 2 0 1 0 0 1 0 0 0 0 0 0 1 0 0 2 0 0 1 0 0 1 1 1 4 0 1 0 0 1 0 4 4 0 0 0 0 0 1 3 3 0 0 1 0 0 0 1 3 0 1 1 0 2 3 0 1 0 1 0 1 5 1 1 1 1 0 2 0 3 6 0 4 1 1 1 0 2 4 8 10 0 1 1 0 103_DM mutations/Mb 1 OK 106 0 0.000 0.118 NaN 0.138 0.162 0.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.89 3.17 1.17 1.96 0.00 1.03 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.90 0.00 0.00 6.19 0.00 0.00 0.62 0.00 0.00 0.86 0.82 1.28 3.70 0.00 1.02 0.00 0.00 0.89 0.00 4.67 3.91 0.00 0.00 0.00 0.00 0.00 0.75 3.18 2.93 0.00 0.00 0.96 0.00 0.00 0.00 3.10 8.05 0.00 0.62 0.91 0.00 1.71 2.46 0.00 0.93 0.00 1.02 0.00 1.26 4.44 1.06 1.17 0.98 1.86 0.00 2.96 0.00 2.79 4.52 0.00 3.90 2.17 1.08 0.96 0.00 5.91 8.52 24.78 26.82 0.00 0.62 0.91 0.00 104_DM # 1 OK 65 1 0.015 0.150 0.056 0.165 0.174 3 1 0 0 0 1 0 1 0 1 1 0 0 0 0 0 1 0 0 1 0 0 0 1 1 1 0 0 0 1 1 0 2 0 0 3 0 0 0 0 2 0 3 2 0 0 0 0 0 0 0 3 0 0 0 0 0 1 0 1 0 0 0 0 1 1 0 1 0 2 0 0 2 0 0 0 0 0 0 2 1 0 2 2 0 1 0 0 3 5 3 7 0 0 0 0 104_DM mutations/Mb 1 OK 65 1 0.015 0.150 0.056 0.165 0.174 2.57 0.82 0.00 0.00 0.00 1.02 0.00 1.26 0.00 1.06 1.17 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.98 0.00 0.00 0.00 0.90 2.95 2.13 0.00 0.00 0.00 0.62 0.91 0.00 1.71 0.00 0.00 2.78 0.00 0.00 0.00 0.00 1.78 0.00 3.50 1.96 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.93 0.00 0.00 0.00 0.00 0.00 2.13 0.00 2.68 0.00 0.00 0.00 0.00 0.86 0.82 0.00 0.93 0.00 2.05 0.00 0.00 1.78 0.00 0.00 0.00 0.00 0.00 0.00 2.79 0.93 0.00 2.12 1.95 0.00 1.08 0.00 0.00 8.86 10.65 9.29 18.78 0.00 0.00 0.00 0.00 105_DM # 1 OK 501 0 0.000 0.082 NaN 0.085 0.100 61 0 0 1 0 0 0 0 22 0 0 0 0 0 0 0 67 2 0 0 0 1 0 0 8 1 0 1 0 0 0 1 9 2 1 0 0 0 0 1 6 0 3 3 0 1 0 0 12 0 1 3 0 0 0 0 2 0 0 0 0 0 0 0 39 4 1 2 0 1 0 0 28 3 0 3 0 0 0 2 121 6 3 0 0 0 0 0 48 15 3 9 0 0 1 3 105_DM mutations/Mb 1 OK 501 0 0.000 0.082 NaN 0.085 0.100 52.29 0.00 0.00 0.93 0.00 0.00 0.00 0.00 19.56 0.00 0.00 0.00 0.00 0.00 0.00 0.00 62.39 1.51 0.00 0.00 0.00 1.08 0.00 0.00 23.64 2.13 0.00 2.68 0.00 0.00 0.00 0.91 7.72 1.64 1.28 0.00 0.00 0.00 0.00 1.26 5.33 0.00 3.50 2.94 0.00 1.03 0.00 0.00 11.17 0.00 1.06 2.93 0.00 0.00 0.00 0.00 5.91 0.00 0.00 0.00 0.00 0.00 0.00 0.00 33.43 3.28 1.28 1.85 0.00 1.02 0.00 0.00 24.89 3.17 0.00 2.94 0.00 0.00 0.00 2.79 112.67 4.52 3.18 0.00 0.00 0.00 0.00 0.00 141.82 31.94 9.29 24.14 0.00 0.00 0.91 2.74 106_DM # 1 OK 66 0 0.000 0.062 NaN 0.063 0.076 6 1 0 1 0 0 0 0 1 0 0 0 0 0 0 0 4 0 0 0 0 0 1 0 0 1 1 0 0 0 0 0 0 0 0 1 0 0 0 0 2 1 0 3 0 0 0 0 0 0 0 5 0 0 0 0 1 0 1 0 0 0 1 0 2 3 0 1 0 1 0 0 6 0 0 0 0 0 0 0 10 0 0 1 0 0 0 0 5 4 1 0 0 0 0 1 106_DM mutations/Mb 1 OK 66 0 0.000 0.062 NaN 0.063 0.076 5.14 0.82 0.00 0.93 0.00 0.00 0.00 0.00 0.89 0.00 0.00 0.00 0.00 0.00 0.00 0.00 3.72 0.00 0.00 0.00 0.00 0.00 0.96 0.00 0.00 2.13 3.10 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 1.78 1.06 0.00 2.94 0.00 0.00 0.00 0.00 0.00 0.00 0.00 4.88 0.00 0.00 0.00 0.00 2.95 0.00 3.10 0.00 0.00 0.00 0.91 0.00 1.71 2.46 0.00 0.93 0.00 1.02 0.00 0.00 5.33 0.00 0.00 0.00 0.00 0.00 0.00 0.00 9.31 0.00 0.00 0.98 0.00 0.00 0.00 0.00 14.77 8.52 3.10 0.00 0.00 0.00 0.00 0.91 111_DM # 1 OK 43 1 0.023 0.260 0.042 0.391 0.389 0 1 0 1 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5 0 1 0 0 1 0 1 3 0 1 0 0 2 1 1 1 0 0 0 0 1 1 0 2 0 0 0 0 2 0 1 0 2 0 0 2 1 0 3 0 0 0 0 0 0 0 0 1 0 1 0 0 1 3 1 0 0 0 0 0 111_DM mutations/Mb 1 OK 43 1 0.023 0.260 0.042 0.391 0.389 0.00 0.82 0.00 0.93 0.00 0.00 0.00 0.00 0.00 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 4.63 0.00 1.02 0.00 0.00 0.89 0.00 1.17 2.94 0.00 1.03 0.00 0.00 1.86 0.75 1.06 0.98 0.00 0.00 0.00 0.00 2.95 2.13 0.00 5.36 0.00 0.00 0.00 0.00 1.71 0.00 1.28 0.00 3.96 0.00 0.00 2.52 0.89 0.00 3.50 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.98 0.00 1.08 0.00 0.00 2.95 6.39 3.10 0.00 0.00 0.00 0.00 0.00 123_DM # 1 OK 59 0 0.000 0.094 NaN 0.093 0.094 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 1 1 1 0 0 0 0 0 0 0 1 2 0 2 0 0 2 0 0 0 0 1 3 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 4 0 1 1 1 0 1 0 0 1 1 0 0 0 0 0 5 3 0 0 0 0 0 0 2 3 3 13 0 0 0 0 123_DM mutations/Mb 1 OK 59 0 0.000 0.094 NaN 0.093 0.094 1.71 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.39 0.93 0.00 0.00 0.98 2.17 1.08 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.62 1.82 0.00 1.71 0.00 0.00 1.85 0.00 0.00 0.00 0.00 0.89 3.17 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.98 0.00 0.00 0.00 0.90 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 3.43 0.00 1.28 0.93 1.98 0.00 1.36 0.00 0.00 1.06 1.17 0.00 0.00 0.00 0.00 0.00 4.66 2.26 0.00 0.00 0.00 0.00 0.00 0.00 5.91 6.39 9.29 34.87 0.00 0.00 0.00 0.00 124_DM # 1 OK 425 5 0.012 0.348 0.331 0.348 0.338 8 2 2 2 0 1 1 2 9 0 0 2 0 0 0 2 4 1 2 1 0 2 0 1 2 2 1 1 0 0 1 0 1 13 1 0 0 0 0 0 5 8 3 7 1 0 0 1 1 6 1 3 0 2 0 0 1 5 0 2 0 4 5 3 4 4 2 13 9 17 3 3 5 3 6 15 15 15 4 2 11 3 7 13 3 4 1 3 8 29 27 41 3 26 3 1 124_DM mutations/Mb 1 OK 425 5 0.012 0.348 0.331 0.348 0.338 6.86 1.64 2.57 1.85 0.00 1.02 1.36 2.52 8.00 0.00 0.00 1.96 0.00 0.00 0.00 2.79 3.72 0.75 2.12 0.98 0.00 2.15 0.00 0.90 5.91 4.26 3.10 2.68 0.00 0.00 0.91 0.00 0.86 10.67 1.28 0.00 0.00 0.00 0.00 0.00 4.44 8.45 3.50 6.85 1.86 0.00 0.00 1.39 0.93 4.52 1.06 2.93 0.00 2.15 0.00 0.00 2.95 10.65 0.00 5.36 0.00 2.50 4.54 2.74 3.43 3.28 2.57 12.04 17.84 17.41 4.09 3.78 4.44 3.17 7.00 14.68 27.93 15.38 5.93 2.79 10.24 2.26 7.42 12.69 6.50 4.30 0.96 2.70 23.64 61.75 83.62 109.97 6.62 16.24 2.72 0.91 130_DM # 1 OK 80 0 0.000 0.196 NaN 0.196 0.173 2 0 2 0 1 0 0 1 0 0 0 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 1 1 0 0 0 1 0 0 0 0 2 1 0 0 0 1 0 1 0 0 0 1 0 11 1 0 1 1 0 0 1 2 1 0 2 0 0 1 1 8 0 3 2 0 0 0 1 8 5 7 3 1 0 0 0 130_DM mutations/Mb 1 OK 80 0 0.000 0.196 NaN 0.196 0.173 1.71 0.00 2.57 0.00 1.98 0.00 0.00 1.26 0.00 0.00 0.00 0.98 0.00 0.00 0.00 0.00 1.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.62 0.00 0.00 0.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.06 1.17 0.00 0.00 0.00 1.48 0.00 0.00 0.00 0.00 1.95 2.17 0.00 0.00 0.00 2.95 0.00 3.10 0.00 0.00 0.00 0.91 0.00 9.43 0.82 0.00 0.93 1.98 0.00 0.00 1.26 1.78 1.06 0.00 1.96 0.00 0.00 1.48 1.39 7.45 0.00 3.18 1.95 0.00 0.00 0.00 0.90 23.64 10.65 21.68 8.05 2.21 0.00 0.00 0.00 131_DM # 1 OK 70 0 0.000 0.090 NaN 0.090 0.091 2 1 1 0 0 0 1 0 1 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 2 1 0 1 0 1 0 0 2 0 0 0 0 0 0 0 1 2 0 1 1 0 1 1 0 0 1 0 0 0 0 0 3 3 2 1 0 0 1 1 2 3 0 2 1 0 0 0 2 1 0 0 0 1 2 1 1 6 6 4 0 1 1 0 131_DM mutations/Mb 1 OK 70 0 0.000 0.090 NaN 0.090 0.091 1.71 0.82 1.28 0.00 0.00 0.00 1.36 0.00 0.89 0.00 0.00 1.96 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.95 2.13 0.00 0.00 0.00 0.00 0.00 0.00 1.71 0.82 0.00 0.93 0.00 1.02 0.00 0.00 1.78 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.93 1.51 0.00 0.98 2.17 0.00 0.96 0.90 0.00 0.00 3.10 0.00 0.00 0.00 0.00 0.00 2.57 2.46 2.57 0.93 0.00 0.00 1.36 1.26 1.78 3.17 0.00 1.96 1.86 0.00 0.00 0.00 1.86 0.75 0.00 0.00 0.00 1.08 1.92 0.90 2.95 12.78 18.58 10.73 0.00 0.62 0.91 0.00 132_DM # 1 OK 112 1 0.009 0.167 0.345 0.170 0.170 8 2 1 1 0 0 0 1 2 1 1 0 0 1 0 0 7 1 0 1 1 0 0 0 0 0 0 0 0 0 0 1 1 1 0 1 0 3 0 0 0 3 0 2 1 0 0 0 5 2 0 4 0 1 0 1 2 1 0 0 0 0 0 0 5 4 0 1 1 1 0 1 3 2 1 4 0 1 1 1 9 0 0 2 0 0 2 1 9 2 0 3 0 0 1 0 132_DM mutations/Mb 1 OK 112 1 0.009 0.167 0.345 0.170 0.170 6.86 1.64 1.28 0.93 0.00 0.00 0.00 1.26 1.78 1.06 1.17 0.00 0.00 1.03 0.00 0.00 6.52 0.75 0.00 0.98 2.17 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.91 0.86 0.82 0.00 0.93 0.00 3.07 0.00 0.00 0.00 3.17 0.00 1.96 1.86 0.00 0.00 0.00 4.66 1.51 0.00 3.90 0.00 1.08 0.00 0.90 5.91 2.13 0.00 0.00 0.00 0.00 0.00 0.00 4.29 3.28 0.00 0.93 1.98 1.02 0.00 1.26 2.67 2.11 1.17 3.91 0.00 1.03 1.48 1.39 8.38 0.00 0.00 1.95 0.00 0.00 1.92 0.90 26.59 4.26 0.00 8.05 0.00 0.00 0.91 0.00 133_DM # 1 OK 71 0 0.000 0.138 NaN 0.147 0.205 1 0 0 1 0 1 0 0 3 1 0 0 0 0 0 0 6 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 2 0 0 1 0 0 1 0 0 1 0 0 0 0 0 0 1 2 1 3 0 0 0 0 1 0 0 0 0 1 0 0 9 2 0 1 0 0 1 0 0 1 1 0 0 0 1 0 8 0 0 0 0 1 0 0 4 2 6 4 0 1 0 0 133_DM mutations/Mb 1 OK 71 0 0.000 0.138 NaN 0.147 0.205 0.86 0.00 0.00 0.93 0.00 1.02 0.00 0.00 2.67 1.06 0.00 0.00 0.00 0.00 0.00 0.00 5.59 0.00 0.00 0.00 0.00 0.00 0.96 0.00 2.95 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.71 0.00 0.00 0.93 0.00 0.00 1.36 0.00 0.00 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.93 1.51 1.06 2.93 0.00 0.00 0.00 0.00 2.95 0.00 0.00 0.00 0.00 0.62 0.00 0.00 7.72 1.64 0.00 0.93 0.00 0.00 1.36 0.00 0.00 1.06 1.17 0.00 0.00 0.00 1.48 0.00 7.45 0.00 0.00 0.00 0.00 1.08 0.00 0.00 11.82 4.26 18.58 10.73 0.00 0.62 0.00 0.00 134_DM # 1 OK 168 1 0.006 0.075 0.366 0.075 0.105 14 0 0 1 0 1 0 0 3 0 3 0 0 0 0 0 12 0 0 1 0 0 0 0 4 2 0 1 0 2 0 1 2 0 0 0 0 0 0 0 2 0 1 0 1 1 0 0 3 1 1 3 0 0 0 0 1 1 1 0 0 2 0 0 15 3 0 3 0 2 1 0 9 1 0 1 2 0 0 0 26 3 0 0 0 0 0 0 19 10 2 5 0 0 1 0 134_DM mutations/Mb 1 OK 168 1 0.006 0.075 0.366 0.075 0.105 12.00 0.00 0.00 0.93 0.00 1.02 0.00 0.00 2.67 0.00 3.50 0.00 0.00 0.00 0.00 0.00 11.17 0.00 0.00 0.98 0.00 0.00 0.00 0.00 11.82 4.26 0.00 2.68 0.00 1.25 0.00 0.91 1.71 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.78 0.00 1.17 0.00 1.86 1.03 0.00 0.00 2.79 0.75 1.06 2.93 0.00 0.00 0.00 0.00 2.95 2.13 3.10 0.00 0.00 1.25 0.00 0.00 12.86 2.46 0.00 2.78 0.00 2.05 1.36 0.00 8.00 1.06 0.00 0.98 3.72 0.00 0.00 0.00 24.21 2.26 0.00 0.00 0.00 0.00 0.00 0.00 56.14 21.29 6.19 13.41 0.00 0.00 0.91 0.00 135_DM # 1 OK 139 4 0.029 0.181 0.148 0.181 0.179 8 0 1 1 0 1 0 0 4 0 0 1 0 0 0 0 8 2 0 0 0 0 0 0 1 0 0 1 0 1 0 0 0 1 1 1 0 0 0 0 3 2 0 0 0 0 0 0 1 0 0 2 0 0 0 1 3 4 0 0 0 0 1 0 10 3 1 1 0 0 1 1 5 0 0 0 1 0 1 0 24 1 0 1 0 0 1 1 14 9 6 8 0 1 0 0 135_DM mutations/Mb 1 OK 139 4 0.029 0.181 0.148 0.181 0.179 6.86 0.00 1.28 0.93 0.00 1.02 0.00 0.00 3.56 0.00 0.00 0.98 0.00 0.00 0.00 0.00 7.45 1.51 0.00 0.00 0.00 0.00 0.00 0.00 2.95 0.00 0.00 2.68 0.00 0.62 0.00 0.00 0.00 0.82 1.28 0.93 0.00 0.00 0.00 0.00 2.67 2.11 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 1.95 0.00 0.00 0.00 0.90 8.86 8.52 0.00 0.00 0.00 0.00 0.91 0.00 8.57 2.46 1.28 0.93 0.00 0.00 1.36 1.26 4.44 0.00 0.00 0.00 1.86 0.00 1.48 0.00 22.35 0.75 0.00 0.98 0.00 0.00 0.96 0.90 41.36 19.16 18.58 21.46 0.00 0.62 0.00 0.00 136_DM # 1 OK 130 0 0.000 0.068 NaN 0.067 0.063 31 1 0 0 1 1 0 0 5 0 1 0 0 0 0 0 16 0 0 1 0 0 0 0 7 1 0 0 0 0 0 0 2 0 0 0 0 0 1 0 3 1 0 1 0 1 0 0 1 1 0 0 0 1 0 0 0 0 1 1 0 2 0 0 11 1 0 1 0 0 0 0 2 0 0 1 0 0 1 0 19 1 0 2 0 0 0 0 6 0 1 3 0 0 0 0 136_DM mutations/Mb 1 OK 130 0 0.000 0.068 NaN 0.067 0.063 26.58 0.82 0.00 0.00 1.98 1.02 0.00 0.00 4.44 0.00 1.17 0.00 0.00 0.00 0.00 0.00 14.90 0.00 0.00 0.98 0.00 0.00 0.00 0.00 20.68 2.13 0.00 0.00 0.00 0.00 0.00 0.00 1.71 0.00 0.00 0.00 0.00 0.00 1.36 0.00 2.67 1.06 0.00 0.98 0.00 1.03 0.00 0.00 0.93 0.75 0.00 0.00 0.00 1.08 0.00 0.00 0.00 0.00 3.10 2.68 0.00 1.25 0.00 0.00 9.43 0.82 0.00 0.93 0.00 0.00 0.00 0.00 1.78 0.00 0.00 0.98 0.00 0.00 1.48 0.00 17.69 0.75 0.00 1.95 0.00 0.00 0.00 0.00 17.73 0.00 3.10 8.05 0.00 0.00 0.00 0.00 137_DM # 1 OK 25 0 0.000 0.151 NaN 0.150 0.140 0 2 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 2 1 0 0 0 1 1 0 1 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 1 137_DM mutations/Mb 1 OK 25 0 0.000 0.151 NaN 0.150 0.140 0.00 1.64 1.28 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.03 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.62 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.17 0.98 0.00 1.03 1.48 1.39 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.68 0.00 0.00 0.00 0.91 1.71 0.82 0.00 0.00 0.00 1.02 1.36 0.00 0.89 0.00 0.00 0.98 1.86 1.03 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 5.36 0.00 0.00 0.91 0.91 138_DM # 1 OK 38 0 0.000 0.208 NaN 0.209 0.070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 2 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 1 1 0 0 1 0 1 1 0 0 0 1 1 0 1 0 0 0 0 0 0 1 2 1 2 0 1 1 0 0 2 3 3 6 0 0 1 0 138_DM mutations/Mb 1 OK 38 0 0.000 0.208 NaN 0.209 0.070 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.17 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 1.06 2.33 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.06 0.00 0.00 0.00 0.00 0.90 0.00 0.00 3.10 2.68 0.00 0.00 0.91 0.00 0.86 0.82 0.00 0.00 0.00 1.02 1.36 0.00 0.89 0.00 0.00 0.00 0.00 0.00 0.00 1.39 1.86 0.75 2.12 0.00 2.17 1.08 0.00 0.00 5.91 6.39 9.29 16.09 0.00 0.00 0.91 0.00 139_DM # 1 OK 107 2 0.019 0.095 0.126 0.092 0.101 2 3 1 3 0 1 0 2 3 1 3 1 1 0 0 0 2 1 0 0 1 0 2 1 1 0 1 1 1 0 2 1 1 1 0 3 2 0 1 0 4 1 1 1 0 0 0 1 1 3 1 0 0 2 0 0 0 2 0 0 0 2 0 1 0 2 0 4 0 0 1 1 0 2 1 1 1 1 1 2 0 1 1 2 0 0 2 0 2 5 3 7 2 0 0 2 139_DM mutations/Mb 1 OK 107 2 0.019 0.095 0.126 0.092 0.101 1.71 2.46 1.28 2.78 0.00 1.02 0.00 2.52 2.67 1.06 3.50 0.98 1.86 0.00 0.00 0.00 1.86 0.75 0.00 0.00 2.17 0.00 1.92 0.90 2.95 0.00 3.10 2.68 2.21 0.00 1.82 0.91 0.86 0.82 0.00 2.78 3.96 0.00 1.36 0.00 3.56 1.06 1.17 0.98 0.00 0.00 0.00 1.39 0.93 2.26 1.06 0.00 0.00 2.15 0.00 0.00 0.00 4.26 0.00 0.00 0.00 1.25 0.00 0.91 0.00 1.64 0.00 3.70 0.00 0.00 1.36 1.26 0.00 2.11 1.17 0.98 1.86 1.03 1.48 2.79 0.00 0.75 1.06 1.95 0.00 0.00 1.92 0.00 5.91 10.65 9.29 18.78 4.42 0.00 0.00 1.83 140_DM # 1 OK 31 0 0.000 0.197 NaN 0.209 0.109 1 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 1 1 0 0 0 0 1 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 1 0 1 2 0 0 2 1 1 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 2 0 2 3 0 1 0 0 140_DM mutations/Mb 1 OK 31 0 0.000 0.197 NaN 0.209 0.109 0.86 0.00 0.00 0.00 0.00 1.02 0.00 0.00 0.00 0.00 0.00 0.98 0.00 0.00 0.00 0.00 1.86 0.75 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.86 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 0.00 1.17 0.98 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 2.17 0.00 0.00 0.00 2.95 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.86 0.00 1.28 1.85 0.00 0.00 2.73 1.26 0.89 0.00 1.17 0.00 0.00 1.03 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 5.91 0.00 6.19 8.05 0.00 0.62 0.00 0.00 141_DM # 1 OK 59 0 0.000 0.137 NaN 0.142 0.119 0 0 0 0 0 0 0 0 1 1 0 0 0 1 0 1 2 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 1 0 1 0 0 0 0 0 1 2 0 3 0 0 1 0 0 0 0 0 0 0 0 0 2 0 3 2 0 0 1 0 4 1 0 1 0 0 0 1 9 2 0 1 0 0 0 0 5 1 4 3 1 0 0 0 141_DM mutations/Mb 1 OK 59 0 0.000 0.137 NaN 0.142 0.119 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.89 1.06 0.00 0.00 0.00 1.03 0.00 1.39 1.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.95 0.00 0.00 0.00 0.00 0.62 0.00 0.00 0.00 0.00 1.28 0.00 0.00 0.00 0.00 0.00 0.89 0.00 1.17 0.00 0.00 0.00 0.00 0.00 0.93 1.51 0.00 2.93 0.00 0.00 0.96 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.71 0.00 3.85 1.85 0.00 0.00 1.36 0.00 3.56 1.06 0.00 0.98 0.00 0.00 0.00 1.39 8.38 1.51 0.00 0.98 0.00 0.00 0.00 0.00 14.77 2.13 12.39 8.05 2.21 0.00 0.00 0.00 142_DM # 1 OK 32 0 0.000 0.341 NaN 0.316 0.375 0 0 0 1 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 3 0 0 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 1 3 0 1 0 0 0 0 0 0 1 0 0 0 1 0 0 0 1 1 0 0 0 0 0 1 1 0 1 0 0 0 1 1 0 0 0 0 1 0 2 4 0 1 0 0 0 0 142_DM mutations/Mb 1 OK 32 0 0.000 0.341 NaN 0.316 0.375 0.00 0.00 0.00 0.93 0.00 1.02 0.00 0.00 0.00 0.00 1.17 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.13 3.10 0.00 0.00 0.00 2.72 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.06 0.00 0.00 0.00 1.03 0.00 0.00 0.93 2.26 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 3.10 0.00 0.00 0.00 0.91 0.00 0.00 0.00 1.28 0.93 0.00 0.00 0.00 0.00 0.00 1.06 1.17 0.00 1.86 0.00 0.00 0.00 0.93 0.75 0.00 0.00 0.00 0.00 0.96 0.00 5.91 8.52 0.00 2.68 0.00 0.00 0.00 0.00 143_DM # 1 OK 95 1 0.011 0.203 0.197 0.202 0.203 4 0 1 0 0 0 1 0 0 1 0 0 2 1 0 3 1 1 0 1 0 0 2 0 0 1 0 0 0 0 0 1 0 0 1 0 0 1 0 1 1 0 2 3 0 1 0 1 0 0 0 0 2 1 1 1 0 1 0 0 0 0 1 1 6 3 0 0 0 0 1 2 1 3 5 3 2 3 1 2 3 1 0 0 1 2 0 3 2 5 4 2 0 0 1 0 143_DM mutations/Mb 1 OK 95 1 0.011 0.203 0.197 0.202 0.203 3.43 0.00 1.28 0.00 0.00 0.00 1.36 0.00 0.00 1.06 0.00 0.00 3.72 1.03 0.00 4.18 0.93 0.75 0.00 0.98 0.00 0.00 1.92 0.00 0.00 2.13 0.00 0.00 0.00 0.00 0.00 0.91 0.00 0.00 1.28 0.00 0.00 1.02 0.00 1.26 0.89 0.00 2.33 2.94 0.00 1.03 0.00 1.39 0.00 0.00 0.00 0.00 4.33 1.08 0.96 0.90 0.00 2.13 0.00 0.00 0.00 0.00 0.91 0.91 5.14 2.46 0.00 0.00 0.00 0.00 1.36 2.52 0.89 3.17 5.84 2.94 3.72 3.08 1.48 2.79 2.79 0.75 0.00 0.00 2.17 2.15 0.00 2.70 5.91 10.65 12.39 5.36 0.00 0.00 0.91 0.00 144_DM # 1 OK 50 0 0.000 0.194 NaN 0.204 0.144 4 1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 2 1 0 0 0 1 0 1 0 0 0 0 0 1 0 0 1 1 0 0 1 0 0 0 1 0 0 2 0 4 2 0 0 0 1 0 0 1 0 0 1 0 0 1 0 2 0 0 3 0 0 0 1 3 4 1 4 0 0 0 1 144_DM mutations/Mb 1 OK 50 0 0.000 0.194 NaN 0.204 0.144 3.43 0.82 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.48 1.39 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.13 0.00 0.00 0.00 0.00 0.00 0.00 0.86 0.00 0.00 1.85 1.98 0.00 0.00 0.00 0.89 0.00 1.17 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.98 2.17 0.00 0.00 0.90 0.00 0.00 0.00 2.68 0.00 0.00 1.82 0.00 3.43 1.64 0.00 0.00 0.00 1.02 0.00 0.00 0.89 0.00 0.00 0.98 0.00 0.00 1.48 0.00 1.86 0.00 0.00 2.93 0.00 0.00 0.00 0.90 8.86 8.52 3.10 10.73 0.00 0.00 0.00 0.91 145_DM # 1 OK 81 0 0.000 0.127 NaN 0.128 0.125 4 1 0 0 0 0 0 0 2 0 1 0 0 0 0 1 0 2 1 1 0 0 0 0 0 1 1 0 0 0 0 0 1 2 1 1 0 0 1 0 1 1 0 1 0 0 0 0 2 0 1 0 0 0 0 0 1 0 1 0 0 0 1 1 3 1 1 1 1 2 0 1 2 3 1 0 0 2 1 0 8 2 2 1 0 1 1 0 3 3 4 5 0 0 0 1 145_DM mutations/Mb 1 OK 81 0 0.000 0.127 NaN 0.128 0.125 3.43 0.82 0.00 0.00 0.00 0.00 0.00 0.00 1.78 0.00 1.17 0.00 0.00 0.00 0.00 1.39 0.00 1.51 1.06 0.98 0.00 0.00 0.00 0.00 0.00 2.13 3.10 0.00 0.00 0.00 0.00 0.00 0.86 1.64 1.28 0.93 0.00 0.00 1.36 0.00 0.89 1.06 0.00 0.98 0.00 0.00 0.00 0.00 1.86 0.00 1.06 0.00 0.00 0.00 0.00 0.00 2.95 0.00 3.10 0.00 0.00 0.00 0.91 0.91 2.57 0.82 1.28 0.93 1.98 2.05 0.00 1.26 1.78 3.17 1.17 0.00 0.00 2.05 1.48 0.00 7.45 1.51 2.12 0.98 0.00 1.08 0.96 0.00 8.86 6.39 12.39 13.41 0.00 0.00 0.00 0.91 146_DM # 1 OK 94 0 0.000 0.069 NaN 0.079 0.058 8 1 1 2 0 1 0 0 1 0 1 0 0 0 0 0 4 1 0 2 0 1 0 1 1 1 0 1 0 0 0 0 1 0 0 1 0 1 0 0 2 1 0 2 0 0 0 0 3 1 0 2 0 0 0 0 2 0 0 0 0 1 1 0 1 1 0 1 0 1 3 0 5 1 0 1 1 0 2 0 9 4 1 1 1 0 1 0 8 0 2 4 0 1 0 0 146_DM mutations/Mb 1 OK 94 0 0.000 0.069 NaN 0.079 0.058 6.86 0.82 1.28 1.85 0.00 1.02 0.00 0.00 0.89 0.00 1.17 0.00 0.00 0.00 0.00 0.00 3.72 0.75 0.00 1.95 0.00 1.08 0.00 0.90 2.95 2.13 0.00 2.68 0.00 0.00 0.00 0.00 0.86 0.00 0.00 0.93 0.00 1.02 0.00 0.00 1.78 1.06 0.00 1.96 0.00 0.00 0.00 0.00 2.79 0.75 0.00 1.95 0.00 0.00 0.00 0.00 5.91 0.00 0.00 0.00 0.00 0.62 0.91 0.00 0.86 0.82 0.00 0.93 0.00 1.02 4.09 0.00 4.44 1.06 0.00 0.98 1.86 0.00 2.96 0.00 8.38 3.02 1.06 0.98 2.17 0.00 0.96 0.00 23.64 0.00 6.19 10.73 0.00 0.62 0.00 0.00 147_DM # 1 OK 141 3 0.021 0.140 0.353 0.145 0.159 7 0 0 0 0 0 0 0 3 0 1 1 0 1 1 1 2 0 0 1 0 0 0 0 0 0 0 3 1 1 0 1 3 1 1 3 0 1 0 1 2 1 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 3 1 1 0 1 0 0 12 1 0 3 0 2 0 1 11 1 1 2 0 0 2 1 17 4 1 2 0 0 0 1 14 6 2 8 1 1 1 1 147_DM mutations/Mb 1 OK 141 3 0.021 0.140 0.353 0.145 0.159 6.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.67 0.00 1.17 0.98 0.00 1.03 1.48 1.39 1.86 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 8.05 2.21 0.62 0.00 0.91 2.57 0.82 1.28 2.78 0.00 1.02 0.00 1.26 1.78 1.06 0.00 0.98 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 6.39 3.10 2.68 0.00 0.62 0.00 0.00 10.29 0.82 0.00 2.78 0.00 2.05 0.00 1.26 9.78 1.06 1.17 1.96 0.00 0.00 2.96 1.39 15.83 3.02 1.06 1.95 0.00 0.00 0.00 0.90 41.36 12.78 6.19 21.46 2.21 0.62 0.91 0.91 160_DM # 1 OK 225 0 0.000 0.138 NaN 0.138 0.133 28 1 1 1 0 1 0 0 8 0 0 0 0 0 0 0 14 3 1 0 1 0 0 0 5 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 5 0 1 1 0 1 0 0 5 0 0 0 0 0 1 0 0 0 0 0 1 1 0 0 32 1 0 1 0 2 1 0 18 2 3 0 0 0 0 1 47 2 2 4 1 0 0 0 18 7 1 1 0 0 0 0 160_DM mutations/Mb 1 OK 225 0 0.000 0.138 NaN 0.138 0.133 24.00 0.82 1.28 0.93 0.00 1.02 0.00 0.00 7.11 0.00 0.00 0.00 0.00 0.00 0.00 0.00 13.04 2.26 1.06 0.00 2.17 0.00 0.00 0.00 14.77 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.82 0.00 0.00 0.00 0.00 0.00 0.00 4.44 0.00 1.17 0.98 0.00 1.03 0.00 0.00 4.66 0.00 0.00 0.00 0.00 0.00 0.96 0.00 0.00 0.00 0.00 0.00 2.21 0.62 0.00 0.00 27.43 0.82 0.00 0.93 0.00 2.05 1.36 0.00 16.00 2.11 3.50 0.00 0.00 0.00 0.00 1.39 43.76 1.51 2.12 3.90 2.17 0.00 0.00 0.00 53.18 14.91 3.10 2.68 0.00 0.00 0.00 0.00 163_DM # 1 OK 181 3 0.017 0.092 0.074 0.090 0.083 12 3 0 2 0 1 0 1 4 1 1 4 1 1 0 0 7 3 0 0 0 0 0 0 3 2 1 0 1 1 0 1 2 5 0 1 0 1 0 1 2 3 3 5 0 0 0 1 3 2 1 2 0 1 1 0 1 3 2 1 0 2 1 0 4 1 1 3 0 2 1 1 9 0 3 4 0 2 0 1 21 1 3 2 0 1 0 0 4 9 6 6 0 0 2 0 163_DM mutations/Mb 1 OK 181 3 0.017 0.092 0.074 0.090 0.083 10.29 2.46 0.00 1.85 0.00 1.02 0.00 1.26 3.56 1.06 1.17 3.91 1.86 1.03 0.00 0.00 6.52 2.26 0.00 0.00 0.00 0.00 0.00 0.00 8.86 4.26 3.10 0.00 2.21 0.62 0.00 0.91 1.71 4.10 0.00 0.93 0.00 1.02 0.00 1.26 1.78 3.17 3.50 4.89 0.00 0.00 0.00 1.39 2.79 1.51 1.06 1.95 0.00 1.08 0.96 0.00 2.95 6.39 6.19 2.68 0.00 1.25 0.91 0.00 3.43 0.82 1.28 2.78 0.00 2.05 1.36 1.26 8.00 0.00 3.50 3.91 0.00 2.05 0.00 1.39 19.55 0.75 3.18 1.95 0.00 1.08 0.00 0.00 11.82 19.16 18.58 16.09 0.00 0.00 1.82 0.00 164_DM # 1 OK 1463 0 0.000 0.088 NaN 0.088 0.088 231 6 0 1 0 1 0 0 64 4 2 1 0 0 0 1 182 4 3 1 0 0 0 0 18 2 0 0 0 0 1 0 22 1 1 0 1 1 0 0 21 0 0 0 0 0 0 0 33 4 1 1 0 0 0 0 12 0 1 1 0 0 0 1 172 5 3 6 0 0 1 0 98 12 5 2 1 1 0 0 328 14 7 5 1 1 2 0 129 22 10 11 0 1 2 1 164_DM mutations/Mb 1 OK 1463 0 0.000 0.088 NaN 0.088 0.088 198.03 4.93 0.00 0.93 0.00 1.02 0.00 0.00 56.89 4.22 2.33 0.98 0.00 0.00 0.00 1.39 169.47 3.02 3.18 0.98 0.00 0.00 0.00 0.00 53.18 4.26 0.00 0.00 0.00 0.00 0.91 0.00 18.86 0.82 1.28 0.00 1.98 1.02 0.00 0.00 18.67 0.00 0.00 0.00 0.00 0.00 0.00 0.00 30.73 3.02 1.06 0.98 0.00 0.00 0.00 0.00 35.45 0.00 3.10 2.68 0.00 0.00 0.00 0.91 147.45 4.10 3.85 5.56 0.00 0.00 1.36 0.00 87.11 12.67 5.84 1.96 1.86 1.03 0.00 0.00 305.41 10.56 7.42 4.88 2.17 1.08 1.92 0.00 381.13 46.85 30.97 29.50 0.00 0.62 1.82 0.91 165_DM # 1 OK 29 0 0.000 0.293 NaN 0.313 0.197 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 1 2 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 1 0 3 0 1 2 0 0 0 0 0 3 0 0 0 0 0 0 1 0 1 2 0 0 1 0 165_DM mutations/Mb 1 OK 29 0 0.000 0.293 NaN 0.313 0.197 0.86 0.82 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.13 3.10 2.68 2.21 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.17 0.00 0.00 1.03 0.00 0.00 0.93 1.51 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.00 3.10 0.00 0.00 0.00 0.00 0.00 0.00 0.82 0.00 0.00 0.00 0.00 1.36 0.00 2.67 0.00 1.17 1.96 0.00 0.00 0.00 0.00 0.00 2.26 0.00 0.00 0.00 0.00 0.00 0.00 2.95 0.00 3.10 5.36 0.00 0.00 0.91 0.00 166_DM # 1 OK 154 0 0.000 0.117 NaN 0.109 0.060 9 1 0 0 0 0 1 3 2 0 1 0 0 2 0 0 2 3 1 0 0 1 0 2 2 1 0 1 0 2 3 1 4 1 2 2 1 0 1 0 0 2 2 3 1 1 1 0 2 1 0 1 0 0 1 0 0 0 1 0 0 4 1 0 8 1 0 2 0 0 0 2 11 5 2 3 1 0 2 2 8 5 0 2 0 0 3 1 6 4 4 8 0 2 2 0 166_DM mutations/Mb 1 OK 154 0 0.000 0.117 NaN 0.109 0.060 7.72 0.82 0.00 0.00 0.00 0.00 1.36 3.78 1.78 0.00 1.17 0.00 0.00 2.05 0.00 0.00 1.86 2.26 1.06 0.00 0.00 1.08 0.00 1.80 5.91 2.13 0.00 2.68 0.00 1.25 2.72 0.91 3.43 0.82 2.57 1.85 1.98 0.00 1.36 0.00 0.00 2.11 2.33 2.94 1.86 1.03 1.48 0.00 1.86 0.75 0.00 0.98 0.00 0.00 0.96 0.00 0.00 0.00 3.10 0.00 0.00 2.50 0.91 0.00 6.86 0.82 0.00 1.85 0.00 0.00 0.00 2.52 9.78 5.28 2.33 2.94 1.86 0.00 2.96 2.79 7.45 3.77 0.00 1.95 0.00 0.00 2.88 0.90 17.73 8.52 12.39 21.46 0.00 1.25 1.82 0.00 167_DM # 1 OK 126 0 0.000 0.109 NaN 0.108 0.124 6 0 0 1 1 2 0 1 4 2 3 0 0 1 0 0 3 3 1 0 0 0 0 0 2 1 0 0 2 3 2 1 5 1 0 0 0 1 0 0 1 5 0 2 0 0 1 1 1 1 1 1 0 0 0 0 1 0 0 0 2 0 6 1 1 2 0 3 0 1 0 0 2 5 0 2 1 0 0 0 4 2 1 1 0 0 0 0 4 9 5 4 0 3 4 2 167_DM mutations/Mb 1 OK 126 0 0.000 0.109 NaN 0.108 0.124 5.14 0.00 0.00 0.93 1.98 2.05 0.00 1.26 3.56 2.11 3.50 0.00 0.00 1.03 0.00 0.00 2.79 2.26 1.06 0.00 0.00 0.00 0.00 0.00 5.91 2.13 0.00 0.00 4.42 1.87 1.82 0.91 4.29 0.82 0.00 0.00 0.00 1.02 0.00 0.00 0.89 5.28 0.00 1.96 0.00 0.00 1.48 1.39 0.93 0.75 1.06 0.98 0.00 0.00 0.00 0.00 2.95 0.00 0.00 0.00 4.42 0.00 5.45 0.91 0.86 1.64 0.00 2.78 0.00 1.02 0.00 0.00 1.78 5.28 0.00 1.96 1.86 0.00 0.00 0.00 3.72 1.51 1.06 0.98 0.00 0.00 0.00 0.00 11.82 19.16 15.48 10.73 0.00 1.87 3.63 1.83 177_DM # 1 OK 95 1 0.011 0.305 0.061 0.306 0.333 4 2 2 0 0 0 0 1 3 2 0 0 0 0 1 3 2 1 1 0 0 0 1 1 1 0 1 0 0 2 0 0 0 2 0 0 0 0 0 0 1 1 1 3 0 0 1 0 1 1 2 3 0 0 0 0 1 1 0 1 0 1 2 2 1 0 1 1 1 0 1 2 1 1 0 2 2 1 0 1 2 0 1 2 0 1 0 0 0 6 5 7 2 0 0 2 177_DM mutations/Mb 1 OK 95 1 0.011 0.305 0.061 0.306 0.333 3.43 1.64 2.57 0.00 0.00 0.00 0.00 1.26 2.67 2.11 0.00 0.00 0.00 0.00 1.48 4.18 1.86 0.75 1.06 0.00 0.00 0.00 0.96 0.90 2.95 0.00 3.10 0.00 0.00 1.25 0.00 0.00 0.00 1.64 0.00 0.00 0.00 0.00 0.00 0.00 0.89 1.06 1.17 2.94 0.00 0.00 1.48 0.00 0.93 0.75 2.12 2.93 0.00 0.00 0.00 0.00 2.95 2.13 0.00 2.68 0.00 0.62 1.82 1.83 0.86 0.00 1.28 0.93 1.98 0.00 1.36 2.52 0.89 1.06 0.00 1.96 3.72 1.03 0.00 1.39 1.86 0.00 1.06 1.95 0.00 1.08 0.00 0.00 0.00 12.78 15.48 18.78 4.42 0.00 0.00 1.83 183_DM # 1 OK 53 1 0.019 0.083 0.117 0.087 0.092 0 0 1 0 0 0 0 0 1 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 1 0 1 1 0 1 0 0 2 0 0 1 0 0 0 0 0 1 1 0 0 0 0 0 0 0 1 1 1 3 0 1 1 0 0 0 1 1 1 1 3 1 1 1 0 0 0 0 2 8 1 7 0 1 0 1 183_DM mutations/Mb 1 OK 53 1 0.019 0.083 0.117 0.087 0.092 0.00 0.00 1.28 0.00 0.00 0.00 0.00 0.00 0.89 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.28 0.93 0.00 0.00 0.00 0.00 0.89 0.00 1.17 0.98 0.00 1.03 0.00 0.00 1.86 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 2.13 3.10 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.28 0.93 1.98 3.07 0.00 1.26 0.89 0.00 0.00 0.00 1.86 1.03 1.48 1.39 2.79 0.75 1.06 0.98 0.00 0.00 0.00 0.00 5.91 17.03 3.10 18.78 0.00 0.62 0.00 0.91 184_DM # 1 OK 66 0 0.000 0.125 NaN 0.203 0.116 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 0 0 3 0 0 0 1 2 2 2 3 0 2 0 0 0 0 1 2 0 0 0 0 1 0 0 0 0 0 0 0 1 2 1 0 0 3 0 0 1 1 2 0 0 0 0 1 0 0 0 0 0 0 1 0 4 3 8 8 0 1 1 0 184_DM mutations/Mb 1 OK 66 0 0.000 0.125 NaN 0.203 0.116 0.00 1.64 1.28 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.93 1.51 0.00 0.00 0.00 0.00 0.00 0.00 2.95 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.71 0.00 0.00 2.78 0.00 0.00 0.00 1.26 1.78 2.11 2.33 2.94 0.00 2.05 0.00 0.00 0.00 0.00 1.06 1.95 0.00 0.00 0.00 0.00 2.95 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.86 1.64 1.28 0.00 0.00 3.07 0.00 0.00 0.89 1.06 2.33 0.00 0.00 0.00 0.00 1.39 0.00 0.00 0.00 0.00 0.00 0.00 0.96 0.00 11.82 6.39 24.78 21.46 0.00 0.62 0.91 0.00 208_DM # 1 OK 26 0 0.000 0.062 NaN 0.113 0.153 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 1 0 0 1 0 0 1 0 0 0 0 0 0 2 1 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 3 4 2 0 0 0 1 208_DM mutations/Mb 1 OK 26 0 0.000 0.062 NaN 0.113 0.153 0.00 0.00 0.00 0.00 0.00 1.02 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.12 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.86 0.00 1.28 0.00 0.00 1.02 0.00 0.00 0.89 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 2.12 0.98 0.00 0.00 0.00 0.00 0.00 0.00 3.10 0.00 0.00 0.00 0.00 0.00 1.71 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.95 6.39 12.39 5.36 0.00 0.00 0.00 0.91 211_DM # 1 OK 81 1 0.012 0.055 0.057 0.056 0.043 5 0 0 0 1 1 0 0 2 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 3 0 0 0 1 0 0 3 1 1 0 1 0 0 0 0 3 0 0 1 0 0 0 0 1 1 0 0 0 1 0 0 5 1 1 0 1 1 0 0 5 0 1 0 0 1 0 1 9 1 1 0 0 0 0 2 6 4 3 6 0 1 0 1 211_DM mutations/Mb 1 OK 81 1 0.012 0.055 0.057 0.056 0.043 4.29 0.00 0.00 0.00 1.98 1.02 0.00 0.00 1.78 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.86 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.68 0.00 0.00 0.00 0.00 2.57 0.00 0.00 0.00 1.98 0.00 0.00 3.78 0.89 1.06 0.00 0.98 0.00 0.00 0.00 0.00 2.79 0.00 0.00 0.98 0.00 0.00 0.00 0.00 2.95 2.13 0.00 0.00 0.00 0.62 0.00 0.00 4.29 0.82 1.28 0.00 1.98 1.02 0.00 0.00 4.44 0.00 1.17 0.00 0.00 1.03 0.00 1.39 8.38 0.75 1.06 0.00 0.00 0.00 0.00 1.80 17.73 8.52 9.29 16.09 0.00 0.62 0.00 0.91 212_DM # 1 OK 35 0 0.000 0.117 NaN 0.122 0.128 1 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 1 0 0 0 0 0 2 1 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 1 0 1 1 0 0 0 0 4 1 0 0 0 0 0 1 0 3 3 3 0 1 0 0 212_DM mutations/Mb 1 OK 35 0 0.000 0.117 NaN 0.122 0.128 0.86 0.00 0.00 0.00 0.00 0.00 1.36 0.00 0.89 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.51 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.68 0.00 0.00 0.00 0.00 0.86 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 2.11 1.17 0.98 0.00 0.00 0.00 0.00 0.93 0.75 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.68 0.00 0.00 0.00 0.00 0.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.89 0.00 1.17 0.98 0.00 0.00 0.00 0.00 3.72 0.75 0.00 0.00 0.00 0.00 0.00 0.90 0.00 6.39 9.29 8.05 0.00 0.62 0.00 0.00 218_DM # 1 OK 102 0 0.000 0.176 NaN 0.188 0.158 1 3 1 1 0 0 0 2 2 1 0 1 0 0 0 3 3 0 1 0 0 0 0 0 2 1 2 0 0 2 0 0 2 2 1 2 0 0 0 0 2 2 4 3 0 1 0 0 0 3 2 3 0 1 0 0 0 0 0 3 0 0 0 0 1 4 1 1 1 0 0 2 1 1 0 1 1 1 0 0 1 0 1 3 0 0 0 0 5 7 3 4 0 3 2 1 218_DM mutations/Mb 1 OK 102 0 0.000 0.176 NaN 0.188 0.158 0.86 2.46 1.28 0.93 0.00 0.00 0.00 2.52 1.78 1.06 0.00 0.98 0.00 0.00 0.00 4.18 2.79 0.00 1.06 0.00 0.00 0.00 0.00 0.00 5.91 2.13 6.19 0.00 0.00 1.25 0.00 0.00 1.71 1.64 1.28 1.85 0.00 0.00 0.00 0.00 1.78 2.11 4.67 2.94 0.00 1.03 0.00 0.00 0.00 2.26 2.12 2.93 0.00 1.08 0.00 0.00 0.00 0.00 0.00 8.05 0.00 0.00 0.00 0.00 0.86 3.28 1.28 0.93 1.98 0.00 0.00 2.52 0.89 1.06 0.00 0.98 1.86 1.03 0.00 0.00 0.93 0.00 1.06 2.93 0.00 0.00 0.00 0.00 14.77 14.91 9.29 10.73 0.00 1.87 1.82 0.91 229_DM # 1 OK 33 1 0.030 0.083 0.024 0.305 0.328 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 0 0 1 0 0 0 0 0 0 1 1 0 0 0 0 0 1 1 0 1 0 0 0 0 2 2 2 0 0 1 3 0 0 1 0 1 0 0 0 0 2 0 0 0 0 1 0 0 1 1 2 2 0 0 0 0 229_DM mutations/Mb 1 OK 33 1 0.030 0.083 0.024 0.305 0.328 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.06 0.00 0.00 0.00 0.00 0.00 1.39 0.00 0.00 1.06 0.00 0.00 0.00 0.00 0.00 2.95 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.85 0.00 0.00 0.00 0.00 0.00 0.00 1.17 0.00 0.00 0.00 0.00 0.00 0.00 0.75 1.06 0.00 0.00 0.00 0.00 0.00 2.95 2.13 0.00 2.68 0.00 0.00 0.00 0.00 1.71 1.64 2.57 0.00 0.00 1.02 4.09 0.00 0.00 1.06 0.00 0.98 0.00 0.00 0.00 0.00 1.86 0.00 0.00 0.00 0.00 1.08 0.00 0.00 2.95 2.13 6.19 5.36 0.00 0.00 0.00 0.00 230_DM # 1 OK 84 0 0.000 0.309 NaN 0.284 0.251 2 1 0 0 1 0 0 2 1 0 0 0 0 0 1 0 1 0 1 0 0 0 1 0 0 1 1 0 0 2 1 1 0 0 0 2 0 0 0 0 1 0 1 4 0 0 0 0 0 1 0 1 0 0 1 0 0 0 1 2 1 0 1 0 1 1 2 1 0 1 1 1 1 0 0 2 0 1 0 0 1 3 1 2 0 0 1 0 2 9 5 11 0 2 2 0 230_DM mutations/Mb 1 OK 84 0 0.000 0.309 NaN 0.284 0.251 1.71 0.82 0.00 0.00 1.98 0.00 0.00 2.52 0.89 0.00 0.00 0.00 0.00 0.00 1.48 0.00 0.93 0.00 1.06 0.00 0.00 0.00 0.96 0.00 0.00 2.13 3.10 0.00 0.00 1.25 0.91 0.91 0.00 0.00 0.00 1.85 0.00 0.00 0.00 0.00 0.89 0.00 1.17 3.91 0.00 0.00 0.00 0.00 0.00 0.75 0.00 0.98 0.00 0.00 0.96 0.00 0.00 0.00 3.10 5.36 2.21 0.00 0.91 0.00 0.86 0.82 2.57 0.93 0.00 1.02 1.36 1.26 0.89 0.00 0.00 1.96 0.00 1.03 0.00 0.00 0.93 2.26 1.06 1.95 0.00 0.00 0.96 0.00 5.91 19.16 15.48 29.50 0.00 1.25 1.82 0.00 231_DM # 1 OK 39 0 0.000 0.087 NaN 0.116 0.116 1 0 1 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 1 2 1 1 0 0 0 0 1 1 2 0 0 1 0 0 1 0 0 1 0 0 0 1 0 0 1 0 1 1 1 0 1 0 2 1 0 0 0 1 1 0 0 1 1 0 0 0 1 1 1 2 0 0 1 1 231_DM mutations/Mb 1 OK 39 0 0.000 0.087 NaN 0.116 0.116 0.86 0.00 1.28 0.00 0.00 0.00 1.36 0.00 0.00 0.00 1.17 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.86 0.00 0.00 1.85 0.00 0.00 0.00 0.00 0.89 2.11 1.17 0.98 0.00 0.00 0.00 0.00 0.93 0.75 2.12 0.00 0.00 1.08 0.00 0.00 2.95 0.00 0.00 2.68 0.00 0.00 0.00 0.91 0.00 0.00 1.28 0.00 1.98 1.02 1.36 0.00 0.89 0.00 2.33 0.98 0.00 0.00 0.00 1.39 0.93 0.00 0.00 0.98 2.17 0.00 0.00 0.00 2.95 2.13 3.10 5.36 0.00 0.00 0.91 0.91 232_DM # 1 OK 37 0 0.000 0.070 NaN 0.079 0.077 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 1 0 0 1 0 0 0 0 1 0 0 2 0 0 0 0 0 0 0 2 1 0 0 0 3 1 0 2 0 0 0 0 1 2 0 0 0 0 0 0 0 0 1 1 0 0 0 1 2 5 2 1 0 2 1 0 232_DM mutations/Mb 1 OK 37 0 0.000 0.070 NaN 0.079 0.077 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.89 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.17 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.28 0.93 0.00 0.00 0.00 0.00 0.89 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.93 0.00 0.00 1.95 0.00 0.00 0.00 0.00 0.00 0.00 0.00 5.36 2.21 0.00 0.00 0.00 2.57 0.82 0.00 1.85 0.00 0.00 0.00 0.00 0.89 2.11 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.06 0.98 0.00 0.00 0.00 0.90 5.91 10.65 6.19 2.68 0.00 1.25 0.91 0.00 233_DM # 1 OK 101 0 0.000 0.139 NaN 0.152 0.133 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 1 0 0 1 0 1 0 0 0 0 1 1 0 0 1 0 2 1 0 0 0 0 3 1 0 8 0 0 0 1 4 2 3 4 0 0 0 0 0 0 0 2 0 0 0 0 3 4 0 1 0 0 0 0 6 0 1 1 1 1 0 0 1 3 2 1 0 1 1 0 4 7 11 10 1 0 0 1 233_DM mutations/Mb 1 OK 101 0 0.000 0.139 NaN 0.152 0.133 0.86 0.00 0.00 0.00 0.00 0.00 0.00 1.26 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 1.06 0.00 0.00 1.08 0.00 0.90 0.00 0.00 0.00 0.00 2.21 0.62 0.00 0.00 0.86 0.00 2.57 0.93 0.00 0.00 0.00 0.00 2.67 1.06 0.00 7.83 0.00 0.00 0.00 1.39 3.72 1.51 3.18 3.90 0.00 0.00 0.00 0.00 0.00 0.00 0.00 5.36 0.00 0.00 0.00 0.00 2.57 3.28 0.00 0.93 0.00 0.00 0.00 0.00 5.33 0.00 1.17 0.98 1.86 1.03 0.00 0.00 0.93 2.26 2.12 0.98 0.00 1.08 0.96 0.00 11.82 14.91 34.07 26.82 2.21 0.00 0.00 0.91 235_DM # 1 OK 53 2 0.038 0.161 0.197 0.158 0.057 0 0 0 0 0 1 0 0 0 0 2 0 0 0 0 0 2 1 0 0 0 0 1 0 0 0 0 0 0 0 1 0 2 0 0 1 0 0 0 0 2 0 0 0 0 0 0 0 1 0 0 2 0 0 2 0 0 2 0 2 0 0 0 0 6 2 2 2 0 0 0 0 0 1 0 0 0 0 0 0 1 1 0 2 0 1 1 0 2 5 2 2 0 1 0 0 235_DM mutations/Mb 1 OK 53 2 0.038 0.161 0.197 0.158 0.057 0.00 0.00 0.00 0.00 0.00 1.02 0.00 0.00 0.00 0.00 2.33 0.00 0.00 0.00 0.00 0.00 1.86 0.75 0.00 0.00 0.00 0.00 0.96 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.91 0.00 1.71 0.00 0.00 0.93 0.00 0.00 0.00 0.00 1.78 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 1.95 0.00 0.00 1.92 0.00 0.00 4.26 0.00 5.36 0.00 0.00 0.00 0.00 5.14 1.64 2.57 1.85 0.00 0.00 0.00 0.00 0.00 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.75 0.00 1.95 0.00 1.08 0.96 0.00 5.91 10.65 6.19 5.36 0.00 0.62 0.00 0.00 236_DM # 1 OK 97 0 0.000 0.103 NaN 0.104 0.095 1 0 1 0 0 0 1 1 4 2 1 0 0 2 0 0 1 0 0 1 0 0 0 1 0 0 0 1 0 1 0 1 2 5 1 2 0 1 0 0 5 2 1 2 0 1 0 1 0 2 1 3 0 0 1 1 1 0 0 2 0 1 1 0 0 3 0 2 0 1 2 0 3 3 4 2 0 0 0 1 4 0 0 2 0 0 1 0 0 2 7 1 2 0 1 1 236_DM mutations/Mb 1 OK 97 0 0.000 0.103 NaN 0.104 0.095 0.86 0.00 1.28 0.00 0.00 0.00 1.36 1.26 3.56 2.11 1.17 0.00 0.00 2.05 0.00 0.00 0.93 0.00 0.00 0.98 0.00 0.00 0.00 0.90 0.00 0.00 0.00 2.68 0.00 0.62 0.00 0.91 1.71 4.10 1.28 1.85 0.00 1.02 0.00 0.00 4.44 2.11 1.17 1.96 0.00 1.03 0.00 1.39 0.00 1.51 1.06 2.93 0.00 0.00 0.96 0.90 2.95 0.00 0.00 5.36 0.00 0.62 0.91 0.00 0.00 2.46 0.00 1.85 0.00 1.02 2.73 0.00 2.67 3.17 4.67 1.96 0.00 0.00 0.00 1.39 3.72 0.00 0.00 1.95 0.00 0.00 0.96 0.00 0.00 4.26 21.68 2.68 4.42 0.00 0.91 0.91 237_DM # 1 OK 28 0 0.000 0.204 NaN 0.204 0.231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 3 1 1 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 2 3 0 0 2 0 2 1 0 0 1 0 0 2 1 1 1 0 1 0 0 237_DM mutations/Mb 1 OK 28 0 0.000 0.204 NaN 0.204 0.231 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.62 0.00 0.00 2.57 0.82 1.28 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.33 1.96 5.59 0.00 0.00 2.79 0.00 1.51 1.06 0.00 0.00 1.08 0.00 0.00 5.91 2.13 3.10 2.68 0.00 0.62 0.00 0.00 240_DM_R # 1 OK 84 1 0.012 0.045 0.039 0.192 0.259 0 1 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 2 1 10 0 0 0 0 2 1 7 7 0 0 1 0 3 3 2 7 0 0 0 0 2 1 0 3 1 1 1 0 0 1 1 1 0 2 0 1 1 0 0 1 0 0 0 0 2 0 1 0 1 0 0 0 1 2 3 5 0 0 0 0 240_DM_R mutations/Mb 1 OK 84 1 0.012 0.045 0.039 0.192 0.259 0.00 0.82 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.17 0.00 0.00 0.00 1.48 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.62 0.00 0.00 1.71 1.64 1.28 9.26 0.00 0.00 0.00 0.00 1.78 1.06 8.17 6.85 0.00 0.00 1.48 0.00 2.79 2.26 2.12 6.83 0.00 0.00 0.00 0.00 5.91 2.13 0.00 8.05 2.21 0.62 0.91 0.00 0.00 0.82 1.28 0.93 0.00 2.05 0.00 1.26 0.89 0.00 0.00 0.98 0.00 0.00 0.00 0.00 1.86 0.00 1.06 0.00 2.17 0.00 0.00 0.00 2.95 4.26 9.29 13.41 0.00 0.00 0.00 0.00 243_DM # 1 OK 91 0 0.000 0.174 NaN 0.171 0.190 2 1 1 0 0 0 0 1 1 0 0 0 0 0 0 1 2 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 1 0 0 0 0 0 2 0 1 2 0 0 0 1 1 0 1 1 0 1 0 0 0 0 1 1 0 1 0 0 5 2 3 1 0 0 2 0 6 2 3 4 0 0 1 0 3 0 0 2 0 0 0 1 3 5 10 10 0 1 1 1 243_DM mutations/Mb 1 OK 91 0 0.000 0.174 NaN 0.171 0.190 1.71 0.82 1.28 0.00 0.00 0.00 0.00 1.26 0.89 0.00 0.00 0.00 0.00 0.00 0.00 1.39 1.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.62 0.00 0.00 0.86 0.00 1.28 0.00 0.00 0.00 0.00 0.00 1.78 0.00 1.17 1.96 0.00 0.00 0.00 1.39 0.93 0.00 1.06 0.98 0.00 1.08 0.00 0.00 0.00 0.00 3.10 2.68 0.00 0.62 0.00 0.00 4.29 1.64 3.85 0.93 0.00 0.00 2.73 0.00 5.33 2.11 3.50 3.91 0.00 0.00 1.48 0.00 2.79 0.00 0.00 1.95 0.00 0.00 0.00 0.90 8.86 10.65 30.97 26.82 0.00 0.62 0.91 0.91 246_DM # 1 OK 34 0 0.000 0.109 NaN 0.120 0.129 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 1 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 3 0 0 1 1 1 0 0 1 0 1 0 0 0 0 0 2 2 0 1 0 0 0 0 6 2 4 1 0 0 0 0 246_DM mutations/Mb 1 OK 34 0 0.000 0.109 NaN 0.120 0.129 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.52 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.91 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.89 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.68 0.00 0.00 0.00 0.00 2.57 0.00 0.00 0.93 1.98 1.02 0.00 0.00 0.89 0.00 1.17 0.00 0.00 0.00 0.00 0.00 1.86 1.51 0.00 0.98 0.00 0.00 0.00 0.00 17.73 4.26 12.39 2.68 0.00 0.00 0.00 0.00 247_DM # 1 OK 937 0 0.000 0.093 NaN 0.093 0.097 124 1 3 2 0 0 0 0 27 0 1 0 0 0 0 1 117 3 1 0 0 0 0 1 11 1 0 0 0 1 0 0 13 1 0 0 0 1 0 1 17 1 0 4 0 0 0 0 27 0 1 3 0 0 0 0 10 0 1 0 0 0 0 0 104 4 1 4 1 0 0 0 69 3 2 7 0 0 1 0 203 8 3 8 0 0 0 1 119 9 4 11 0 0 0 1 247_DM mutations/Mb 1 OK 937 0 0.000 0.093 NaN 0.093 0.097 106.30 0.82 3.85 1.85 0.00 0.00 0.00 0.00 24.00 0.00 1.17 0.00 0.00 0.00 0.00 1.39 108.94 2.26 1.06 0.00 0.00 0.00 0.00 0.90 32.50 2.13 0.00 0.00 0.00 0.62 0.00 0.00 11.14 0.82 0.00 0.00 0.00 1.02 0.00 1.26 15.11 1.06 0.00 3.91 0.00 0.00 0.00 0.00 25.14 0.00 1.06 2.93 0.00 0.00 0.00 0.00 29.55 0.00 3.10 0.00 0.00 0.00 0.00 0.00 89.16 3.28 1.28 3.70 1.98 0.00 0.00 0.00 61.34 3.17 2.33 6.85 0.00 0.00 1.48 0.00 189.02 6.03 3.18 7.81 0.00 0.00 0.00 0.90 351.59 19.16 12.39 29.50 0.00 0.00 0.00 0.91 253_DM # 1 OK 41 0 0.000 0.202 NaN 0.181 0.181 1 1 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 2 0 0 0 0 0 0 0 0 0 1 1 0 0 1 0 0 0 0 2 0 0 1 0 4 0 1 0 0 1 0 0 2 1 1 1 0 0 0 0 1 0 0 1 0 1 0 0 2 2 4 4 0 0 0 0 253_DM mutations/Mb 1 OK 41 0 0.000 0.202 NaN 0.181 0.181 0.86 0.82 0.00 0.93 0.00 0.00 0.00 1.26 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.90 2.95 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.28 0.00 0.00 0.00 0.00 0.00 1.78 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.06 0.98 0.00 0.00 0.96 0.00 0.00 0.00 0.00 5.36 0.00 0.00 0.91 0.00 3.43 0.00 1.28 0.00 0.00 1.02 0.00 0.00 1.78 1.06 1.17 0.98 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.98 0.00 1.08 0.00 0.00 5.91 4.26 12.39 10.73 0.00 0.00 0.00 0.00 254_DM # 1 OK 100 1 0.010 0.127 0.142 0.127 0.122 4 0 0 0 0 0 0 0 1 0 0 1 1 1 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 1 0 0 4 0 0 0 0 2 4 1 1 0 0 0 0 1 1 0 0 0 0 0 0 4 0 0 0 0 0 0 0 1 1 1 1 0 1 0 0 5 2 1 1 1 0 1 1 5 5 12 28 0 1 0 0 254_DM mutations/Mb 1 OK 100 1 0.010 0.127 0.142 0.127 0.122 3.43 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.89 0.00 0.00 0.98 1.86 1.03 0.00 2.79 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.91 0.00 0.00 0.82 0.00 0.00 0.00 0.00 0.00 0.00 0.89 0.00 0.00 3.91 0.00 0.00 0.00 0.00 1.86 3.02 1.06 0.98 0.00 0.00 0.00 0.00 2.95 2.13 0.00 0.00 0.00 0.00 0.00 0.00 3.43 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.89 1.06 1.17 0.98 0.00 1.03 0.00 0.00 4.66 1.51 1.06 0.98 2.17 0.00 0.96 0.90 14.77 10.65 37.16 75.10 0.00 0.62 0.00 0.00 255_DM # 1 OK 41 0 0.000 0.213 NaN 0.219 0.219 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 1 1 1 0 0 0 1 0 0 0 0 0 2 0 0 0 0 1 0 3 0 0 0 0 0 2 0 0 0 0 0 0 0 1 0 2 1 1 0 0 0 0 0 0 0 1 0 0 2 1 1 0 1 0 0 0 2 2 0 0 2 0 0 0 0 1 1 2 5 0 0 1 0 255_DM mutations/Mb 1 OK 41 0 0.000 0.213 NaN 0.219 0.219 0.00 0.00 0.00 0.00 0.00 0.00 1.36 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.39 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.90 2.95 2.13 0.00 0.00 0.00 0.62 0.00 0.00 0.00 0.00 0.00 1.85 0.00 0.00 0.00 0.00 0.89 0.00 3.50 0.00 0.00 0.00 0.00 0.00 1.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.95 0.00 6.19 2.68 2.21 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.98 0.00 0.00 2.52 0.89 1.06 0.00 0.98 0.00 0.00 0.00 2.79 1.86 0.00 0.00 1.95 0.00 0.00 0.00 0.00 2.95 2.13 6.19 13.41 0.00 0.00 0.91 0.00 256_DM # 1 OK 40 0 0.000 0.133 NaN 0.190 0.028 0 0 0 0 0 1 0 1 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 1 0 0 1 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 2 0 0 0 0 1 0 1 2 0 0 0 1 0 0 0 0 1 0 2 1 1 1 0 1 0 0 0 2 2 0 2 0 0 0 0 0 2 2 3 3 0 1 0 0 256_DM mutations/Mb 1 OK 40 0 0.000 0.133 NaN 0.190 0.028 0.00 0.00 0.00 0.00 0.00 1.02 0.00 1.26 0.00 0.00 0.00 0.00 1.86 0.00 0.00 0.00 0.00 0.00 0.00 0.98 0.00 0.00 0.00 0.90 0.00 0.00 3.10 0.00 0.00 0.62 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 1.95 0.00 0.00 0.00 0.00 2.95 0.00 3.10 5.36 0.00 0.00 0.00 0.91 0.00 0.00 0.00 0.00 1.98 0.00 2.73 1.26 0.89 1.06 0.00 0.98 0.00 0.00 0.00 2.79 1.86 0.00 2.12 0.00 0.00 0.00 0.00 0.00 5.91 4.26 9.29 8.05 0.00 0.62 0.00 0.00 257_DM # 1 OK 138 1 0.007 0.149 0.116 0.150 0.179 3 2 2 1 0 0 2 1 3 0 4 3 0 2 0 1 2 2 2 0 0 1 0 1 1 2 0 1 0 0 1 1 2 1 0 0 2 1 0 0 0 2 3 1 0 0 0 1 0 0 0 1 2 0 0 0 0 1 0 1 0 2 2 0 1 1 2 1 1 0 0 2 3 1 0 1 2 3 1 0 4 3 2 2 0 0 0 2 7 11 10 11 0 2 2 3 257_DM mutations/Mb 1 OK 138 1 0.007 0.149 0.116 0.150 0.179 2.57 1.64 2.57 0.93 0.00 0.00 2.73 1.26 2.67 0.00 4.67 2.94 0.00 2.05 0.00 1.39 1.86 1.51 2.12 0.00 0.00 1.08 0.00 0.90 2.95 4.26 0.00 2.68 0.00 0.00 0.91 0.91 1.71 0.82 0.00 0.00 3.96 1.02 0.00 0.00 0.00 2.11 3.50 0.98 0.00 0.00 0.00 1.39 0.00 0.00 0.00 0.98 4.33 0.00 0.00 0.00 0.00 2.13 0.00 2.68 0.00 1.25 1.82 0.00 0.86 0.82 2.57 0.93 1.98 0.00 0.00 2.52 2.67 1.06 0.00 0.98 3.72 3.08 1.48 0.00 3.72 2.26 2.12 1.95 0.00 0.00 0.00 1.80 20.68 23.42 30.97 29.50 0.00 1.25 1.82 2.74 258_DM # 1 OK 155 2 0.013 0.171 0.139 0.173 0.314 10 5 5 3 0 0 0 0 7 1 0 3 0 0 0 0 5 1 2 2 0 0 0 0 6 3 3 2 1 2 1 1 3 1 0 3 0 0 0 0 0 1 2 0 0 1 1 1 3 1 2 3 0 2 1 0 1 2 0 0 0 3 1 0 1 5 1 2 2 0 4 3 1 0 2 1 0 0 0 2 2 3 1 5 2 1 1 3 6 2 1 0 1 3 1 4 258_DM mutations/Mb 1 OK 155 2 0.013 0.171 0.139 0.173 0.314 8.57 4.10 6.42 2.78 0.00 0.00 0.00 0.00 6.22 1.06 0.00 2.94 0.00 0.00 0.00 0.00 4.66 0.75 2.12 1.95 0.00 0.00 0.00 0.00 17.73 6.39 9.29 5.36 2.21 1.25 0.91 0.91 2.57 0.82 0.00 2.78 0.00 0.00 0.00 0.00 0.00 1.06 2.33 0.00 0.00 1.03 1.48 1.39 2.79 0.75 2.12 2.93 0.00 2.15 0.96 0.00 2.95 4.26 0.00 0.00 0.00 1.87 0.91 0.00 0.86 4.10 1.28 1.85 3.96 0.00 5.45 3.78 0.89 0.00 2.33 0.98 0.00 0.00 0.00 2.79 1.86 2.26 1.06 4.88 4.33 1.08 0.96 2.70 17.73 4.26 3.10 0.00 2.21 1.87 0.91 3.66 259_DM # 1 OK 102 1 0.010 0.250 0.281 0.250 0.280 2 1 2 1 0 1 0 0 1 1 2 0 0 0 0 2 2 0 1 0 0 1 1 1 0 0 0 0 0 0 1 1 2 1 1 1 0 2 0 1 3 0 3 1 0 0 0 0 4 0 0 3 0 0 0 0 0 1 1 2 0 0 1 0 1 1 1 0 1 3 0 1 2 1 1 1 0 0 1 0 4 1 1 1 2 0 1 1 2 6 8 5 1 4 2 1 259_DM mutations/Mb 1 OK 102 1 0.010 0.250 0.281 0.250 0.280 1.71 0.82 2.57 0.93 0.00 1.02 0.00 0.00 0.89 1.06 2.33 0.00 0.00 0.00 0.00 2.79 1.86 0.00 1.06 0.00 0.00 1.08 0.96 0.90 0.00 0.00 0.00 0.00 0.00 0.00 0.91 0.91 1.71 0.82 1.28 0.93 0.00 2.05 0.00 1.26 2.67 0.00 3.50 0.98 0.00 0.00 0.00 0.00 3.72 0.00 0.00 2.93 0.00 0.00 0.00 0.00 0.00 2.13 3.10 5.36 0.00 0.00 0.91 0.00 0.86 0.82 1.28 0.00 1.98 3.07 0.00 1.26 1.78 1.06 1.17 0.98 0.00 0.00 1.48 0.00 3.72 0.75 1.06 0.98 4.33 0.00 0.96 0.90 5.91 12.78 24.78 13.41 2.21 2.50 1.82 0.91 25_DM # 1 OK 96 1 0.010 0.113 0.256 0.122 0.137 0 0 0 0 0 0 0 0 1 1 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 0 1 0 0 0 0 1 3 1 6 0 1 1 6 1 2 1 6 0 0 1 1 0 1 0 2 0 4 0 2 2 4 0 2 1 0 0 1 1 0 0 1 3 0 2 0 0 1 1 1 0 1 0 1 4 4 7 9 0 0 0 2 25_DM mutations/Mb 1 OK 96 1 0.010 0.113 0.256 0.122 0.137 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.89 1.06 0.00 0.00 0.00 1.03 0.00 1.39 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.86 1.64 0.00 0.93 0.00 0.00 0.00 0.00 0.89 3.17 1.17 5.87 0.00 1.03 1.48 8.37 0.93 1.51 1.06 5.86 0.00 0.00 0.96 0.90 0.00 2.13 0.00 5.36 0.00 2.50 0.00 1.83 1.71 3.28 0.00 1.85 1.98 0.00 0.00 1.26 0.89 0.00 0.00 0.98 5.59 0.00 2.96 0.00 0.00 0.75 1.06 0.98 0.00 1.08 0.00 0.90 11.82 8.52 21.68 24.14 0.00 0.00 0.00 1.83 260_DM # 1 OK 140 1 0.007 0.147 0.442 0.176 0.053 2 2 0 5 0 4 2 1 2 4 1 2 1 3 0 2 2 2 1 3 0 1 1 0 2 0 0 0 0 2 1 1 1 3 4 4 0 2 1 0 1 3 4 4 0 2 1 1 2 0 0 6 0 1 0 1 0 1 2 2 0 1 1 0 2 2 1 0 0 1 1 0 2 3 0 5 0 3 1 0 2 1 3 0 0 1 0 2 3 2 2 3 0 3 1 1 260_DM mutations/Mb 1 OK 140 1 0.007 0.147 0.442 0.176 0.053 1.71 1.64 0.00 4.63 0.00 4.10 2.73 1.26 1.78 4.22 1.17 1.96 1.86 3.08 0.00 2.79 1.86 1.51 1.06 2.93 0.00 1.08 0.96 0.00 5.91 0.00 0.00 0.00 0.00 1.25 0.91 0.91 0.86 2.46 5.13 3.70 0.00 2.05 1.36 0.00 0.89 3.17 4.67 3.91 0.00 2.05 1.48 1.39 1.86 0.00 0.00 5.86 0.00 1.08 0.00 0.90 0.00 2.13 6.19 5.36 0.00 0.62 0.91 0.00 1.71 1.64 1.28 0.00 0.00 1.02 1.36 0.00 1.78 3.17 0.00 4.89 0.00 3.08 1.48 0.00 1.86 0.75 3.18 0.00 0.00 1.08 0.00 1.80 8.86 4.26 6.19 8.05 0.00 1.87 0.91 0.91 261_DM # 1 OK 118 2 0.017 0.147 0.108 0.145 0.142 1 0 1 2 1 2 0 0 0 0 0 3 0 1 0 0 2 0 0 2 0 0 0 2 0 2 2 0 0 1 1 0 0 0 1 3 1 1 0 0 4 1 2 0 0 0 0 0 0 0 2 2 0 1 0 2 1 2 0 0 0 0 0 0 2 3 1 1 1 0 0 0 5 6 2 5 0 1 1 0 3 3 0 2 1 0 0 0 4 5 7 16 1 2 0 0 261_DM mutations/Mb 1 OK 118 2 0.017 0.147 0.108 0.145 0.142 0.86 0.00 1.28 1.85 1.98 2.05 0.00 0.00 0.00 0.00 0.00 2.94 0.00 1.03 0.00 0.00 1.86 0.00 0.00 1.95 0.00 0.00 0.00 1.80 0.00 4.26 6.19 0.00 0.00 0.62 0.91 0.00 0.00 0.00 1.28 2.78 1.98 1.02 0.00 0.00 3.56 1.06 2.33 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.12 1.95 0.00 1.08 0.00 1.80 2.95 4.26 0.00 0.00 0.00 0.00 0.00 0.00 1.71 2.46 1.28 0.93 1.98 0.00 0.00 0.00 4.44 6.34 2.33 4.89 0.00 1.03 1.48 0.00 2.79 2.26 0.00 1.95 2.17 0.00 0.00 0.00 11.82 10.65 21.68 42.92 2.21 1.25 0.00 0.00 262_DM # 1 OK 32 1 0.031 0.182 0.175 0.245 0.224 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 2 1 0 0 0 0 2 1 0 0 0 0 1 0 1 0 0 0 0 0 0 3 1 0 0 0 0 1 1 0 0 0 0 0 0 1 0 0 0 0 1 1 0 1 0 0 1 0 0 0 0 0 1 0 0 0 0 0 0 2 2 2 2 0 0 0 0 262_DM mutations/Mb 1 OK 32 1 0.031 0.182 0.175 0.245 0.224 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.26 0.00 0.00 1.17 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.13 0.00 2.68 0.00 1.25 0.91 0.00 0.00 0.00 0.00 1.85 1.98 0.00 0.00 0.00 0.00 1.06 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 3.18 0.98 0.00 0.00 0.00 0.00 2.95 2.13 0.00 0.00 0.00 0.00 0.00 0.00 0.86 0.00 0.00 0.00 0.00 1.02 1.36 0.00 0.89 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.75 0.00 0.00 0.00 0.00 0.00 0.00 5.91 4.26 6.19 5.36 0.00 0.00 0.00 0.00 263_DM # 1 OK 129 1 0.008 0.153 0.153 0.161 0.186 3 2 0 2 0 1 0 1 2 2 1 2 1 1 0 2 1 1 2 1 0 0 1 1 0 0 0 0 0 3 0 3 1 1 1 1 1 0 0 0 4 2 3 3 1 1 1 0 0 1 1 1 1 1 1 0 1 1 1 1 0 0 0 0 3 3 3 2 1 2 1 1 4 2 2 4 0 2 0 0 1 3 1 3 1 0 1 1 4 5 9 3 0 1 2 1 263_DM mutations/Mb 1 OK 129 1 0.008 0.153 0.153 0.161 0.186 2.57 1.64 0.00 1.85 0.00 1.02 0.00 1.26 1.78 2.11 1.17 1.96 1.86 1.03 0.00 2.79 0.93 0.75 2.12 0.98 0.00 0.00 0.96 0.90 0.00 0.00 0.00 0.00 0.00 1.87 0.00 2.74 0.86 0.82 1.28 0.93 1.98 0.00 0.00 0.00 3.56 2.11 3.50 2.94 1.86 1.03 1.48 0.00 0.00 0.75 1.06 0.98 2.17 1.08 0.96 0.00 2.95 2.13 3.10 2.68 0.00 0.00 0.00 0.00 2.57 2.46 3.85 1.85 1.98 2.05 1.36 1.26 3.56 2.11 2.33 3.91 0.00 2.05 0.00 0.00 0.93 2.26 1.06 2.93 2.17 0.00 0.96 0.90 11.82 10.65 27.87 8.05 0.00 0.62 1.82 0.91 264_DM # 1 OK 24 0 0.000 0.149 NaN 0.191 0.119 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 0 1 0 2 0 1 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 0 1 1 0 0 0 0 0 2 0 0 0 2 1 0 0 0 0 0 0 3 2 0 0 0 1 0 0 264_DM mutations/Mb 1 OK 24 0 0.000 0.149 NaN 0.191 0.119 0.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.91 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.33 0.00 0.00 0.00 0.00 1.39 0.00 1.51 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.62 0.00 0.00 0.86 0.00 0.00 0.00 0.00 1.02 1.36 0.00 0.00 0.00 0.00 0.00 3.72 0.00 0.00 0.00 1.86 0.75 0.00 0.00 0.00 0.00 0.00 0.00 8.86 4.26 0.00 0.00 0.00 0.62 0.00 0.00 26_DM # 1 OK 74 1 0.014 0.140 0.126 0.165 0.176 1 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 2 0 1 0 0 0 0 0 0 1 1 0 0 0 0 0 2 1 0 0 0 0 0 0 1 2 0 1 0 1 0 3 0 3 0 2 0 0 1 0 0 1 0 1 0 0 0 2 7 0 1 1 2 1 0 0 7 0 0 0 1 0 0 0 9 0 2 0 0 0 0 0 3 5 4 2 0 0 0 1 26_DM mutations/Mb 1 OK 74 1 0.014 0.140 0.126 0.165 0.176 0.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.89 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.86 0.00 1.06 0.00 0.00 0.00 0.00 0.00 0.00 2.13 3.10 0.00 0.00 0.00 0.00 0.00 1.71 0.82 0.00 0.00 0.00 0.00 0.00 0.00 0.89 2.11 0.00 0.98 0.00 1.03 0.00 4.18 0.00 2.26 0.00 1.95 0.00 0.00 0.96 0.00 0.00 2.13 0.00 2.68 0.00 0.00 0.00 1.83 6.00 0.00 1.28 0.93 3.96 1.02 0.00 0.00 6.22 0.00 0.00 0.00 1.86 0.00 0.00 0.00 8.38 0.00 2.12 0.00 0.00 0.00 0.00 0.00 8.86 10.65 12.39 5.36 0.00 0.00 0.00 0.91 27_DM # 1 OK 155 0 0.000 0.097 NaN 0.102 0.112 7 2 1 0 1 0 0 0 6 0 1 1 1 0 0 0 6 1 1 0 0 0 0 0 1 0 1 0 0 1 1 0 6 3 1 3 0 0 1 0 2 0 4 3 2 7 3 9 6 0 2 3 0 0 0 0 3 0 0 0 0 4 3 0 8 0 1 2 0 1 1 0 6 1 1 2 1 0 1 0 7 1 1 0 0 0 1 1 8 2 3 5 1 2 1 0 27_DM mutations/Mb 1 OK 155 0 0.000 0.097 NaN 0.102 0.112 6.00 1.64 1.28 0.00 1.98 0.00 0.00 0.00 5.33 0.00 1.17 0.98 1.86 0.00 0.00 0.00 5.59 0.75 1.06 0.00 0.00 0.00 0.00 0.00 2.95 0.00 3.10 0.00 0.00 0.62 0.91 0.00 5.14 2.46 1.28 2.78 0.00 0.00 1.36 0.00 1.78 0.00 4.67 2.94 3.72 7.18 4.44 12.55 5.59 0.00 2.12 2.93 0.00 0.00 0.00 0.00 8.86 0.00 0.00 0.00 0.00 2.50 2.72 0.00 6.86 0.00 1.28 1.85 0.00 1.02 1.36 0.00 5.33 1.06 1.17 1.96 1.86 0.00 1.48 0.00 6.52 0.75 1.06 0.00 0.00 0.00 0.96 0.90 23.64 4.26 9.29 13.41 2.21 1.25 0.91 0.00 28_DM # 1 OK 348 2 0.006 0.199 0.190 0.214 0.241 40 7 5 6 0 0 0 2 31 3 3 2 0 0 0 2 22 3 2 3 1 0 1 1 4 2 0 3 1 3 3 2 7 5 2 2 0 3 1 0 11 6 4 2 3 4 3 3 5 5 5 4 1 0 0 3 0 2 4 2 0 8 2 2 10 2 3 4 2 2 2 0 14 1 2 5 1 3 1 0 10 0 2 2 1 0 0 2 4 8 5 4 0 2 3 2 28_DM mutations/Mb 1 OK 348 2 0.006 0.199 0.190 0.214 0.241 34.29 5.75 6.42 5.56 0.00 0.00 0.00 2.52 27.56 3.17 3.50 1.96 0.00 0.00 0.00 2.79 20.48 2.26 2.12 2.93 2.17 0.00 0.96 0.90 11.82 4.26 0.00 8.05 2.21 1.87 2.72 1.83 6.00 4.10 2.57 1.85 0.00 3.07 1.36 0.00 9.78 6.34 4.67 1.96 5.59 4.10 4.44 4.18 4.66 3.77 5.30 3.90 2.17 0.00 0.00 2.70 0.00 4.26 12.39 5.36 0.00 5.00 1.82 1.83 8.57 1.64 3.85 3.70 3.96 2.05 2.73 0.00 12.44 1.06 2.33 4.89 1.86 3.08 1.48 0.00 9.31 0.00 2.12 1.95 2.17 0.00 0.00 1.80 11.82 17.03 15.48 10.73 0.00 1.25 2.72 1.83 295_DM # 1 OK 84 1 0.012 0.045 0.025 0.228 0.255 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 3 3 3 10 0 0 0 0 0 2 5 6 0 1 1 0 5 0 7 4 0 0 0 0 1 1 1 3 0 0 0 0 1 1 1 1 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 1 0 0 0 2 2 3 3 5 0 0 1 1 295_DM mutations/Mb 1 OK 84 1 0.012 0.045 0.025 0.228 0.255 0.00 0.82 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.13 0.00 0.00 0.00 0.00 0.00 0.00 2.57 2.46 3.85 9.26 0.00 0.00 0.00 0.00 0.00 2.11 5.84 5.87 0.00 1.03 1.48 0.00 4.66 0.00 7.42 3.90 0.00 0.00 0.00 0.00 2.95 2.13 3.10 8.05 0.00 0.00 0.00 0.00 0.86 0.82 1.28 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.39 0.93 0.75 1.06 0.98 0.00 0.00 0.00 1.80 5.91 6.39 9.29 13.41 0.00 0.00 0.91 0.91 296_DM # 1 OK 536 2 0.004 0.064 0.066 0.068 0.099 89 0 0 0 0 0 0 0 25 0 0 0 0 0 0 0 68 3 1 0 0 0 0 1 6 0 0 0 0 0 1 0 12 0 2 6 0 0 0 0 12 1 2 4 0 0 0 1 12 4 6 4 0 2 0 0 5 2 1 1 1 0 0 0 55 5 2 3 0 0 1 1 23 1 1 4 0 0 1 0 90 9 1 4 2 1 0 0 43 5 3 8 0 1 0 0 296_DM mutations/Mb 1 OK 536 2 0.004 0.064 0.066 0.068 0.099 76.30 0.00 0.00 0.00 0.00 0.00 0.00 0.00 22.22 0.00 0.00 0.00 0.00 0.00 0.00 0.00 63.32 2.26 1.06 0.00 0.00 0.00 0.00 0.90 17.73 0.00 0.00 0.00 0.00 0.00 0.91 0.00 10.29 0.00 2.57 5.56 0.00 0.00 0.00 0.00 10.67 1.06 2.33 3.91 0.00 0.00 0.00 1.39 11.17 3.02 6.36 3.90 0.00 2.15 0.00 0.00 14.77 4.26 3.10 2.68 2.21 0.00 0.00 0.00 47.15 4.10 2.57 2.78 0.00 0.00 1.36 1.26 20.45 1.06 1.17 3.91 0.00 0.00 1.48 0.00 83.80 6.79 1.06 3.90 4.33 1.08 0.00 0.00 127.04 10.65 9.29 21.46 0.00 0.62 0.00 0.00 297_DM # 1 OK 93 0 0.000 0.040 NaN 0.197 0.199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3 5 5 7 0 0 0 0 5 3 3 8 0 0 0 0 4 6 7 7 0 1 0 0 2 0 1 7 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 1 1 1 0 0 0 1 0 1 0 0 0 0 1 2 2 4 0 0 0 1 297_DM mutations/Mb 1 OK 93 0 0.000 0.040 NaN 0.197 0.199 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.39 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.57 4.10 6.42 6.48 0.00 0.00 0.00 0.00 4.44 3.17 3.50 7.83 0.00 0.00 0.00 0.00 3.72 4.52 7.42 6.83 0.00 1.08 0.00 0.00 5.91 0.00 3.10 18.78 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.85 0.00 0.00 1.36 0.00 0.00 0.00 0.00 0.98 1.86 1.03 0.00 0.00 0.00 0.75 0.00 0.98 0.00 0.00 0.00 0.00 2.95 4.26 6.19 10.73 0.00 0.00 0.00 0.91 298_DM # 1 OK 178 1 0.006 0.228 0.030 0.252 0.277 8 7 1 1 0 0 1 0 1 1 0 2 1 1 1 0 4 2 0 2 0 1 2 1 0 0 2 2 2 1 3 0 3 5 5 7 0 1 2 0 2 2 3 10 0 3 0 1 3 2 4 4 0 0 0 0 1 1 1 4 1 0 0 1 4 3 0 1 1 2 0 0 4 0 0 4 0 3 1 2 6 5 2 5 0 0 1 1 6 4 3 4 1 1 1 0 298_DM mutations/Mb 1 OK 178 1 0.006 0.228 0.030 0.252 0.277 6.86 5.75 1.28 0.93 0.00 0.00 1.36 0.00 0.89 1.06 0.00 1.96 1.86 1.03 1.48 0.00 3.72 1.51 0.00 1.95 0.00 1.08 1.92 0.90 0.00 0.00 6.19 5.36 4.42 0.62 2.72 0.00 2.57 4.10 6.42 6.48 0.00 1.02 2.73 0.00 1.78 2.11 3.50 9.78 0.00 3.08 0.00 1.39 2.79 1.51 4.24 3.90 0.00 0.00 0.00 0.00 2.95 2.13 3.10 10.73 2.21 0.00 0.00 0.91 3.43 2.46 0.00 0.93 1.98 2.05 0.00 0.00 3.56 0.00 0.00 3.91 0.00 3.08 1.48 2.79 5.59 3.77 2.12 4.88 0.00 0.00 0.96 0.90 17.73 8.52 9.29 10.73 2.21 0.62 0.91 0.00 29_DM # 1 OK 14 0 0.000 0.068 NaN 0.110 NaN 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 1 1 1 0 2 1 0 1 0 2 0 0 0 0 0 0 0 1 2 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29_DM mutations/Mb 1 OK 14 0 0.000 0.068 NaN 0.110 NaN 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 1.06 1.17 0.98 0.00 2.05 1.48 0.00 0.93 0.00 2.12 0.00 0.00 0.00 0.00 0.00 0.00 0.00 3.10 5.36 0.00 0.00 0.00 0.00 0.00 0.82 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 30_DM # 1 OK 235 1 0.004 0.073 0.035 0.079 0.132 10 4 3 3 0 0 1 0 4 1 1 1 1 1 0 1 11 0 1 0 0 0 0 1 2 1 2 0 0 2 0 1 2 1 5 5 1 1 0 0 6 7 9 8 1 4 2 10 3 8 3 2 0 2 1 1 0 1 1 2 1 4 1 5 3 3 1 1 3 1 2 2 4 1 4 2 1 0 2 1 7 5 1 3 0 1 3 0 8 10 5 9 0 1 1 1 30_DM mutations/Mb 1 OK 235 1 0.004 0.073 0.035 0.079 0.132 8.57 3.28 3.85 2.78 0.00 0.00 1.36 0.00 3.56 1.06 1.17 0.98 1.86 1.03 0.00 1.39 10.24 0.00 1.06 0.00 0.00 0.00 0.00 0.90 5.91 2.13 6.19 0.00 0.00 1.25 0.00 0.91 1.71 0.82 6.42 4.63 1.98 1.02 0.00 0.00 5.33 7.39 10.51 7.83 1.86 4.10 2.96 13.95 2.79 6.03 3.18 1.95 0.00 2.15 0.96 0.90 0.00 2.13 3.10 5.36 2.21 2.50 0.91 4.57 2.57 2.46 1.28 0.93 5.95 1.02 2.73 2.52 3.56 1.06 4.67 1.96 1.86 0.00 2.96 1.39 6.52 3.77 1.06 2.93 0.00 1.08 2.88 0.00 23.64 21.29 15.48 24.14 0.00 0.62 0.91 0.91 327_DM # 1 OK 51 1 0.020 0.153 0.029 0.179 0.181 0 1 2 0 0 0 0 0 0 0 0 1 0 0 0 0 2 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 1 1 2 0 0 0 0 0 2 1 0 0 0 0 0 0 2 2 1 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 2 1 0 1 0 0 1 0 0 6 1 0 1 0 0 0 0 4 3 5 3 0 1 0 0 327_DM mutations/Mb 1 OK 51 1 0.020 0.153 0.029 0.179 0.181 0.00 0.82 2.57 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.98 0.00 0.00 0.00 0.00 1.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.13 0.00 0.00 0.00 0.00 0.00 0.00 0.86 0.82 1.28 1.85 0.00 0.00 0.00 0.00 0.00 2.11 1.17 0.00 0.00 0.00 0.00 0.00 0.00 1.51 2.12 0.98 0.00 0.00 0.00 0.00 0.00 2.13 0.00 0.00 0.00 0.00 0.91 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.52 0.89 0.00 1.17 0.00 0.00 1.03 0.00 0.00 5.59 0.75 0.00 0.98 0.00 0.00 0.00 0.00 11.82 6.39 15.48 8.05 0.00 0.62 0.00 0.00 328_DM # 1 OK 111 1 0.009 0.290 0.354 0.290 0.282 9 2 1 5 0 1 0 0 3 3 1 0 0 1 0 1 3 0 1 0 0 0 1 0 2 1 1 0 0 0 2 1 1 2 0 2 0 1 0 0 3 3 1 2 1 0 0 0 1 1 1 0 1 1 1 0 0 1 0 1 0 2 0 1 3 0 2 0 0 1 1 0 4 1 2 1 1 0 1 0 4 0 0 2 1 0 3 0 1 6 2 5 0 0 0 4 328_DM mutations/Mb 1 OK 111 1 0.009 0.290 0.354 0.290 0.282 7.72 1.64 1.28 4.63 0.00 1.02 0.00 0.00 2.67 3.17 1.17 0.00 0.00 1.03 0.00 1.39 2.79 0.00 1.06 0.00 0.00 0.00 0.96 0.00 5.91 2.13 3.10 0.00 0.00 0.00 1.82 0.91 0.86 1.64 0.00 1.85 0.00 1.02 0.00 0.00 2.67 3.17 1.17 1.96 1.86 0.00 0.00 0.00 0.93 0.75 1.06 0.00 2.17 1.08 0.96 0.00 0.00 2.13 0.00 2.68 0.00 1.25 0.00 0.91 2.57 0.00 2.57 0.00 0.00 1.02 1.36 0.00 3.56 1.06 2.33 0.98 1.86 0.00 1.48 0.00 3.72 0.00 0.00 1.95 2.17 0.00 2.88 0.00 2.95 12.78 6.19 13.41 0.00 0.00 0.00 3.66 329_DM # 1 OK 13331 7 0.001 0.255 0.280 0.255 0.259 7 14 2 2 1 0 7 7 6 9 4 2 6 1 3 4 3 2 2 0 1 4 28 15 1 2 0 0 5 4 24 19 20 42 5 3 0 1 1 3 21 10 11 4 3 1 1 2 11 10 5 2 1 2 4 11 3 7 1 1 1 1 13 9 1193 1913 150 315 1 6 1 1 2196 1804 369 422 1 1 5 1 1278 881 3 2 2 3 8 3 1655 634 7 9 7 12 48 5 329_DM mutations/Mb 1 OK 13331 7 0.001 0.255 0.280 0.255 0.259 6.00 11.49 2.57 1.85 1.98 0.00 9.54 8.81 5.33 9.50 4.67 1.96 11.17 1.03 4.44 5.58 2.79 1.51 2.12 0.00 2.17 4.30 26.90 13.51 2.95 4.26 0.00 0.00 11.04 2.50 21.78 17.37 17.15 34.48 6.42 2.78 0.00 1.02 1.36 3.78 18.67 10.56 12.84 3.91 5.59 1.03 1.48 2.79 10.24 7.54 5.30 1.95 2.17 2.15 3.84 9.91 8.86 14.91 3.10 2.68 2.21 0.62 11.80 8.23 1022.72 1570.50 192.55 291.74 1.98 6.14 1.36 1.26 1952.05 1905.19 430.75 412.88 1.86 1.03 7.41 1.39 1189.98 664.31 3.18 1.95 4.33 3.23 7.69 2.70 4889.71 1349.99 21.68 24.14 15.46 7.50 43.56 4.57 330_DM # 1 OK 149 3 0.020 0.214 0.040 0.235 0.246 0 1 1 1 0 0 1 1 2 4 0 1 0 2 0 1 0 2 2 2 0 0 0 1 2 1 2 1 0 3 0 1 2 1 1 1 0 2 1 0 3 3 5 4 0 2 3 2 2 3 4 2 0 1 0 1 1 3 2 1 0 1 1 0 1 2 4 3 0 1 0 1 1 2 1 4 2 1 1 0 3 3 2 1 2 0 2 2 1 5 5 8 2 2 1 2 330_DM mutations/Mb 1 OK 149 3 0.020 0.214 0.040 0.235 0.246 0.00 0.82 1.28 0.93 0.00 0.00 1.36 1.26 1.78 4.22 0.00 0.98 0.00 2.05 0.00 1.39 0.00 1.51 2.12 1.95 0.00 0.00 0.00 0.90 5.91 2.13 6.19 2.68 0.00 1.87 0.00 0.91 1.71 0.82 1.28 0.93 0.00 2.05 1.36 0.00 2.67 3.17 5.84 3.91 0.00 2.05 4.44 2.79 1.86 2.26 4.24 1.95 0.00 1.08 0.00 0.90 2.95 6.39 6.19 2.68 0.00 0.62 0.91 0.00 0.86 1.64 5.13 2.78 0.00 1.02 0.00 1.26 0.89 2.11 1.17 3.91 3.72 1.03 1.48 0.00 2.79 2.26 2.12 0.98 4.33 0.00 1.92 1.80 2.95 10.65 15.48 21.46 4.42 1.25 0.91 1.83 331_DM # 1 OK 176 3 0.017 0.198 0.255 0.200 0.231 5 4 3 2 0 1 0 1 6 0 3 2 0 0 0 0 2 4 5 3 1 2 2 2 2 4 0 2 0 0 0 3 0 5 2 1 0 0 0 2 3 1 0 6 0 0 2 0 2 3 2 5 0 1 1 1 2 3 1 2 0 2 0 0 5 3 0 3 0 2 0 0 4 4 4 3 2 1 3 1 2 3 1 1 0 0 2 3 3 8 5 3 1 1 2 0 331_DM mutations/Mb 1 OK 176 3 0.017 0.198 0.255 0.200 0.231 4.29 3.28 3.85 1.85 0.00 1.02 0.00 1.26 5.33 0.00 3.50 1.96 0.00 0.00 0.00 0.00 1.86 3.02 5.30 2.93 2.17 2.15 1.92 1.80 5.91 8.52 0.00 5.36 0.00 0.00 0.00 2.74 0.00 4.10 2.57 0.93 0.00 0.00 0.00 2.52 2.67 1.06 0.00 5.87 0.00 0.00 2.96 0.00 1.86 2.26 2.12 4.88 0.00 1.08 0.96 0.90 5.91 6.39 3.10 5.36 0.00 1.25 0.00 0.00 4.29 2.46 0.00 2.78 0.00 2.05 0.00 0.00 3.56 4.22 4.67 2.94 3.72 1.03 4.44 1.39 1.86 2.26 1.06 0.98 0.00 0.00 1.92 2.70 8.86 17.03 15.48 8.05 2.21 0.62 1.82 0.00 332_DM # 1 OK 66 1 0.015 0.152 0.178 0.141 0.123 1 2 1 1 1 0 0 0 1 0 1 0 0 0 0 2 0 0 1 1 1 0 0 0 0 2 1 0 0 1 0 0 1 1 1 1 0 0 0 0 0 0 1 1 0 0 0 0 1 1 2 0 0 0 0 1 2 1 0 1 0 1 1 0 0 1 0 0 0 1 0 0 4 1 2 0 0 1 0 0 1 1 1 1 0 0 0 2 3 3 2 2 2 4 0 0 332_DM mutations/Mb 1 OK 66 1 0.015 0.152 0.178 0.141 0.123 0.86 1.64 1.28 0.93 1.98 0.00 0.00 0.00 0.89 0.00 1.17 0.00 0.00 0.00 0.00 2.79 0.00 0.00 1.06 0.98 2.17 0.00 0.00 0.00 0.00 4.26 3.10 0.00 0.00 0.62 0.00 0.00 0.86 0.82 1.28 0.93 0.00 0.00 0.00 0.00 0.00 0.00 1.17 0.98 0.00 0.00 0.00 0.00 0.93 0.75 2.12 0.00 0.00 0.00 0.00 0.90 5.91 2.13 0.00 2.68 0.00 0.62 0.91 0.00 0.00 0.82 0.00 0.00 0.00 1.02 0.00 0.00 3.56 1.06 2.33 0.00 0.00 1.03 0.00 0.00 0.93 0.75 1.06 0.98 0.00 0.00 0.00 1.80 8.86 6.39 6.19 5.36 4.42 2.50 0.00 0.00 333_DM # 1 OK 87 3 0.034 0.304 0.251 0.333 0.397 2 1 1 2 0 0 0 0 1 0 0 1 0 1 1 1 3 1 0 1 0 0 0 0 2 1 1 2 0 1 0 0 1 1 0 0 0 0 0 0 1 4 2 1 0 0 1 0 0 1 0 1 0 0 0 0 1 3 0 1 1 2 1 0 0 4 1 1 1 1 1 0 2 1 0 0 0 1 1 0 2 1 0 5 0 1 1 0 2 5 5 5 0 1 0 0 333_DM mutations/Mb 1 OK 87 3 0.034 0.304 0.251 0.333 0.397 1.71 0.82 1.28 1.85 0.00 0.00 0.00 0.00 0.89 0.00 0.00 0.98 0.00 1.03 1.48 1.39 2.79 0.75 0.00 0.98 0.00 0.00 0.00 0.00 5.91 2.13 3.10 5.36 0.00 0.62 0.00 0.00 0.86 0.82 0.00 0.00 0.00 0.00 0.00 0.00 0.89 4.22 2.33 0.98 0.00 0.00 1.48 0.00 0.00 0.75 0.00 0.98 0.00 0.00 0.00 0.00 2.95 6.39 0.00 2.68 2.21 1.25 0.91 0.00 0.00 3.28 1.28 0.93 1.98 1.02 1.36 0.00 1.78 1.06 0.00 0.00 0.00 1.03 1.48 0.00 1.86 0.75 0.00 4.88 0.00 1.08 0.96 0.00 5.91 10.65 15.48 13.41 0.00 0.62 0.00 0.00 334_DM # 1 OK 105 1 0.010 0.245 0.328 0.265 0.310 10 1 0 1 0 0 0 0 2 1 1 0 0 0 0 0 5 0 0 0 0 0 1 0 1 0 1 0 1 0 0 0 3 2 2 1 0 0 0 0 1 0 1 2 0 1 0 1 3 2 0 1 0 0 0 0 0 1 0 0 0 0 0 0 8 1 1 2 0 0 0 0 8 1 2 0 0 0 0 1 10 1 0 2 0 0 0 0 4 7 2 7 0 1 1 0 334_DM mutations/Mb 1 OK 105 1 0.010 0.245 0.328 0.265 0.310 8.57 0.82 0.00 0.93 0.00 0.00 0.00 0.00 1.78 1.06 1.17 0.00 0.00 0.00 0.00 0.00 4.66 0.00 0.00 0.00 0.00 0.00 0.96 0.00 2.95 0.00 3.10 0.00 2.21 0.00 0.00 0.00 2.57 1.64 2.57 0.93 0.00 0.00 0.00 0.00 0.89 0.00 1.17 1.96 0.00 1.03 0.00 1.39 2.79 1.51 0.00 0.98 0.00 0.00 0.00 0.00 0.00 2.13 0.00 0.00 0.00 0.00 0.00 0.00 6.86 0.82 1.28 1.85 0.00 0.00 0.00 0.00 7.11 1.06 2.33 0.00 0.00 0.00 0.00 1.39 9.31 0.75 0.00 1.95 0.00 0.00 0.00 0.00 11.82 14.91 6.19 18.78 0.00 0.62 0.91 0.00 340_DM # 1 OK 99 2 0.020 0.184 0.196 0.184 0.181 5 1 0 0 0 0 0 0 0 2 1 0 2 2 0 0 3 0 1 0 0 0 0 1 0 0 0 0 0 2 0 0 1 1 1 0 1 0 0 0 2 1 1 1 1 2 0 0 0 1 4 1 0 0 2 0 0 2 0 0 0 1 0 0 2 2 1 3 2 1 0 0 1 0 1 1 1 1 1 2 6 3 0 4 0 1 0 3 4 3 6 5 0 0 1 1 340_DM mutations/Mb 1 OK 99 2 0.020 0.184 0.196 0.184 0.181 4.29 0.82 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.11 1.17 0.00 3.72 2.05 0.00 0.00 2.79 0.00 1.06 0.00 0.00 0.00 0.00 0.90 0.00 0.00 0.00 0.00 0.00 1.25 0.00 0.00 0.86 0.82 1.28 0.00 1.98 0.00 0.00 0.00 1.78 1.06 1.17 0.98 1.86 2.05 0.00 0.00 0.00 0.75 4.24 0.98 0.00 0.00 1.92 0.00 0.00 4.26 0.00 0.00 0.00 0.62 0.00 0.00 1.71 1.64 1.28 2.78 3.96 1.02 0.00 0.00 0.89 0.00 1.17 0.98 1.86 1.03 1.48 2.79 5.59 2.26 0.00 3.90 0.00 1.08 0.00 2.70 11.82 6.39 18.58 13.41 0.00 0.00 0.91 0.91 345-DM # 1 OK 152 2 0.013 0.144 0.072 0.232 0.294 5 4 2 2 0 1 1 0 6 1 1 0 0 2 1 1 6 1 1 3 0 0 2 0 2 2 0 1 0 2 0 0 2 5 2 6 0 1 0 0 4 1 1 4 1 1 1 0 3 3 1 3 1 1 0 1 2 2 1 1 1 0 2 0 4 2 1 3 0 2 2 0 5 2 2 2 1 1 1 1 5 2 2 2 0 0 0 0 5 3 2 1 0 1 0 2 345-DM mutations/Mb 1 OK 152 2 0.013 0.144 0.072 0.232 0.294 4.29 3.28 2.57 1.85 0.00 1.02 1.36 0.00 5.33 1.06 1.17 0.00 0.00 2.05 1.48 1.39 5.59 0.75 1.06 2.93 0.00 0.00 1.92 0.00 5.91 4.26 0.00 2.68 0.00 1.25 0.00 0.00 1.71 4.10 2.57 5.56 0.00 1.02 0.00 0.00 3.56 1.06 1.17 3.91 1.86 1.03 1.48 0.00 2.79 2.26 1.06 2.93 2.17 1.08 0.00 0.90 5.91 4.26 3.10 2.68 2.21 0.00 1.82 0.00 3.43 1.64 1.28 2.78 0.00 2.05 2.73 0.00 4.44 2.11 2.33 1.96 1.86 1.03 1.48 1.39 4.66 1.51 2.12 1.95 0.00 0.00 0.00 0.00 14.77 6.39 6.19 2.68 0.00 0.62 0.00 1.83 346-DM # 1 OK 77 1 0.013 0.127 0.025 0.258 0.280 5 0 0 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 4 0 0 0 0 2 1 2 3 0 0 0 0 1 1 2 4 0 0 0 0 1 1 1 3 0 0 0 1 4 0 0 1 0 0 0 1 4 1 1 0 0 2 1 0 5 0 0 2 0 0 0 1 3 3 4 4 0 1 0 1 346-DM mutations/Mb 1 OK 77 1 0.013 0.127 0.025 0.258 0.280 4.29 0.00 0.00 0.93 0.00 0.00 0.00 0.00 1.78 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.64 1.28 3.70 0.00 0.00 0.00 0.00 1.78 1.06 2.33 2.94 0.00 0.00 0.00 0.00 0.93 0.75 2.12 3.90 0.00 0.00 0.00 0.00 2.95 2.13 3.10 8.05 0.00 0.00 0.00 0.91 3.43 0.00 0.00 0.93 0.00 0.00 0.00 1.26 3.56 1.06 1.17 0.00 0.00 2.05 1.48 0.00 4.66 0.00 0.00 1.95 0.00 0.00 0.00 0.90 8.86 6.39 12.39 10.73 0.00 0.62 0.00 0.91 347-DM # 1 OK 110 0 0.000 0.080 NaN 0.214 0.294 7 0 0 0 0 0 0 0 6 1 2 0 0 0 0 0 4 1 0 0 0 0 0 1 0 3 1 0 1 0 0 1 2 2 2 3 0 0 0 0 5 1 6 5 0 0 0 0 3 2 0 3 0 0 0 0 2 0 1 1 0 1 0 0 4 0 2 2 0 2 0 0 6 0 0 1 0 0 0 1 3 1 1 0 0 0 0 0 3 7 5 4 0 0 0 1 347-DM mutations/Mb 1 OK 110 0 0.000 0.080 NaN 0.214 0.294 6.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 5.33 1.06 2.33 0.00 0.00 0.00 0.00 0.00 3.72 0.75 0.00 0.00 0.00 0.00 0.00 0.90 0.00 6.39 3.10 0.00 2.21 0.00 0.00 0.91 1.71 1.64 2.57 2.78 0.00 0.00 0.00 0.00 4.44 1.06 7.00 4.89 0.00 0.00 0.00 0.00 2.79 1.51 0.00 2.93 0.00 0.00 0.00 0.00 5.91 0.00 3.10 2.68 0.00 0.62 0.00 0.00 3.43 0.00 2.57 1.85 0.00 2.05 0.00 0.00 5.33 0.00 0.00 0.98 0.00 0.00 0.00 1.39 2.79 0.75 1.06 0.00 0.00 0.00 0.00 0.00 8.86 14.91 15.48 10.73 0.00 0.00 0.00 0.91 348-DM # 1 OK 356 3 0.008 0.114 0.189 0.120 0.115 27 0 1 1 0 1 1 0 22 1 1 2 0 0 1 0 18 1 1 2 0 0 0 1 4 1 0 1 0 1 0 0 7 2 3 9 0 0 0 0 6 1 1 5 0 0 0 0 10 2 5 4 0 0 0 0 1 3 1 5 1 1 0 1 23 1 0 1 1 1 2 1 17 1 1 3 0 0 1 2 38 4 2 5 0 0 3 0 30 15 19 27 1 0 1 0 348-DM mutations/Mb 1 OK 356 3 0.008 0.114 0.189 0.120 0.115 23.15 0.00 1.28 0.93 0.00 1.02 1.36 0.00 19.56 1.06 1.17 1.96 0.00 0.00 1.48 0.00 16.76 0.75 1.06 1.95 0.00 0.00 0.00 0.90 11.82 2.13 0.00 2.68 0.00 0.62 0.00 0.00 6.00 1.64 3.85 8.34 0.00 0.00 0.00 0.00 5.33 1.06 1.17 4.89 0.00 0.00 0.00 0.00 9.31 1.51 5.30 3.90 0.00 0.00 0.00 0.00 2.95 6.39 3.10 13.41 2.21 0.62 0.00 0.91 19.72 0.82 0.00 0.93 1.98 1.02 2.73 1.26 15.11 1.06 1.17 2.94 0.00 0.00 1.48 2.79 35.38 3.02 2.12 4.88 0.00 0.00 2.88 0.00 88.64 31.94 58.84 72.42 2.21 0.00 0.91 0.00 349-DM # 1 OK 105 2 0.019 0.045 0.033 0.102 0.102 3 2 1 0 1 0 0 1 2 2 2 0 0 1 0 0 1 2 0 0 0 0 0 1 1 0 0 0 0 0 0 0 4 2 1 8 0 1 0 0 6 5 5 7 0 0 0 0 3 3 5 7 0 0 0 0 2 2 2 0 0 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 1 1 0 1 0 2 1 0 0 1 0 1 2 6 2 0 0 1 0 349-DM mutations/Mb 1 OK 105 2 0.019 0.045 0.033 0.102 0.102 2.57 1.64 1.28 0.00 1.98 0.00 0.00 1.26 1.78 2.11 2.33 0.00 0.00 1.03 0.00 0.00 0.93 1.51 0.00 0.00 0.00 0.00 0.00 0.90 2.95 0.00 0.00 0.00 0.00 0.00 0.00 0.00 3.43 1.64 1.28 7.41 0.00 1.02 0.00 0.00 5.33 5.28 5.84 6.85 0.00 0.00 0.00 0.00 2.79 2.26 5.30 6.83 0.00 0.00 0.00 0.00 5.91 4.26 6.19 0.00 0.00 0.00 0.91 0.00 0.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.89 0.00 0.00 0.00 0.00 1.03 1.48 0.00 0.93 0.00 2.12 0.98 0.00 0.00 0.96 0.00 2.95 4.26 18.58 5.36 0.00 0.00 0.91 0.00 350-DM # 1 OK 166 1 0.006 0.052 0.014 0.084 0.095 14 0 0 0 0 0 1 0 4 1 0 0 0 0 0 0 9 0 0 0 0 0 0 0 2 0 0 0 0 0 0 0 3 3 7 15 0 0 0 0 9 1 9 7 0 0 0 0 3 4 5 7 0 0 0 0 2 1 2 2 0 0 0 0 6 0 0 1 2 0 0 1 6 0 0 0 1 0 0 0 14 0 1 1 1 0 0 0 6 8 3 3 0 0 0 1 350-DM mutations/Mb 1 OK 166 1 0.006 0.052 0.014 0.084 0.095 12.00 0.00 0.00 0.00 0.00 0.00 1.36 0.00 3.56 1.06 0.00 0.00 0.00 0.00 0.00 0.00 8.38 0.00 0.00 0.00 0.00 0.00 0.00 0.00 5.91 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.57 2.46 8.99 13.89 0.00 0.00 0.00 0.00 8.00 1.06 10.51 6.85 0.00 0.00 0.00 0.00 2.79 3.02 5.30 6.83 0.00 0.00 0.00 0.00 5.91 2.13 6.19 5.36 0.00 0.00 0.00 0.00 5.14 0.00 0.00 0.93 3.96 0.00 0.00 1.26 5.33 0.00 0.00 0.00 1.86 0.00 0.00 0.00 13.04 0.00 1.06 0.98 2.17 0.00 0.00 0.00 17.73 17.03 9.29 8.05 0.00 0.00 0.00 0.91 351-DM # 1 OK 99 0 0.000 0.064 NaN 0.083 0.084 6 1 0 0 0 0 0 0 1 0 1 0 0 0 0 0 5 0 1 0 0 1 1 1 0 0 0 0 0 0 0 0 1 1 1 6 0 0 1 0 6 1 4 3 0 0 0 1 1 1 3 4 0 0 1 0 0 0 0 2 0 0 0 1 2 1 0 1 2 0 0 0 1 2 0 2 0 0 0 0 5 0 0 0 1 0 2 1 5 7 3 6 0 2 0 0 351-DM mutations/Mb 1 OK 99 0 0.000 0.064 NaN 0.083 0.084 5.14 0.82 0.00 0.00 0.00 0.00 0.00 0.00 0.89 0.00 1.17 0.00 0.00 0.00 0.00 0.00 4.66 0.00 1.06 0.00 0.00 1.08 0.96 0.90 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.86 0.82 1.28 5.56 0.00 0.00 1.36 0.00 5.33 1.06 4.67 2.94 0.00 0.00 0.00 1.39 0.93 0.75 3.18 3.90 0.00 0.00 0.96 0.00 0.00 0.00 0.00 5.36 0.00 0.00 0.00 0.91 1.71 0.82 0.00 0.93 3.96 0.00 0.00 0.00 0.89 2.11 0.00 1.96 0.00 0.00 0.00 0.00 4.66 0.00 0.00 0.00 2.17 0.00 1.92 0.90 14.77 14.91 9.29 16.09 0.00 1.25 0.00 0.00 352-DM # 1 OK 52 1 0.019 0.232 0.440 0.233 0.260 0 1 0 0 0 1 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 4 0 0 1 0 0 1 2 0 0 0 0 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 1 1 0 1 0 2 0 2 0 0 1 2 0 1 0 1 0 0 2 0 0 0 0 0 0 0 2 5 5 5 0 0 0 0 352-DM mutations/Mb 1 OK 52 1 0.019 0.232 0.440 0.233 0.260 0.00 0.82 0.00 0.00 0.00 1.02 0.00 1.26 0.00 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.13 12.39 0.00 0.00 0.62 0.00 0.00 0.86 1.64 0.00 0.00 0.00 0.00 0.00 0.00 0.89 0.00 1.17 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.13 6.19 5.36 0.00 0.00 0.91 0.91 0.00 0.82 0.00 1.85 0.00 2.05 0.00 0.00 0.89 2.11 0.00 0.98 0.00 1.03 0.00 0.00 1.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 5.91 10.65 15.48 13.41 0.00 0.00 0.00 0.00 353-DM # 1 OK 50 0 0.000 0.046 NaN 0.256 0.227 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 4 1 1 2 0 0 0 0 2 2 2 3 0 0 0 0 1 3 1 2 0 0 0 0 0 0 1 4 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 1 0 0 0 0 1 1 0 1 0 0 0 0 3 3 2 3 0 0 0 0 353-DM mutations/Mb 1 OK 50 0 0.000 0.046 NaN 0.256 0.227 0.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.39 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.95 2.13 0.00 0.00 0.00 0.00 0.00 0.00 3.43 0.82 1.28 1.85 0.00 0.00 0.00 0.00 1.78 2.11 2.33 2.94 0.00 0.00 0.00 0.00 0.93 2.26 1.06 1.95 0.00 0.00 0.00 0.00 0.00 0.00 3.10 10.73 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.36 0.00 0.00 1.06 0.00 0.98 0.00 0.00 0.00 0.00 0.93 0.75 0.00 0.98 0.00 0.00 0.00 0.00 8.86 6.39 6.19 8.05 0.00 0.00 0.00 0.00 354-DM # 1 OK 70 0 0.000 0.188 NaN 0.212 0.205 1 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 2 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 3 1 1 1 0 0 1 0 0 0 2 1 0 0 0 0 0 0 1 0 0 1 0 1 2 0 1 1 0 0 0 0 1 2 0 0 1 0 0 0 1 1 1 1 1 1 1 0 0 1 1 2 0 0 0 1 6 10 4 8 1 0 1 0 354-DM mutations/Mb 1 OK 70 0 0.000 0.188 NaN 0.212 0.205 0.86 0.00 0.00 0.00 0.00 1.02 0.00 0.00 0.00 0.00 0.00 0.00 1.86 0.00 0.00 0.00 1.86 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.95 2.13 0.00 0.00 0.00 0.00 0.00 0.00 2.57 0.82 1.28 0.93 0.00 0.00 1.36 0.00 0.00 0.00 2.33 0.98 0.00 0.00 0.00 0.00 0.00 0.00 1.06 0.00 0.00 1.08 0.00 0.90 5.91 0.00 3.10 2.68 0.00 0.00 0.00 0.00 0.86 1.64 0.00 0.00 1.98 0.00 0.00 0.00 0.89 1.06 1.17 0.98 1.86 1.03 1.48 0.00 0.00 0.75 1.06 1.95 0.00 0.00 0.00 0.90 17.73 21.29 12.39 21.46 2.21 0.00 0.91 0.00 355-DM # 1 OK 64 1 0.016 0.196 0.385 0.200 0.203 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 1 3 1 0 0 0 0 0 1 1 2 0 1 0 0 1 2 0 2 0 0 0 0 0 1 1 1 0 1 0 0 2 2 0 1 0 0 0 0 1 0 1 3 0 1 0 0 0 1 2 2 1 0 1 0 5 9 5 3 0 1 1 0 355-DM mutations/Mb 1 OK 64 1 0.016 0.196 0.385 0.200 0.203 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.62 0.00 0.00 0.86 0.82 3.85 0.93 0.00 0.00 0.00 0.00 0.00 1.06 1.17 1.96 0.00 1.03 0.00 0.00 0.93 1.51 0.00 1.95 0.00 0.00 0.00 0.00 0.00 2.13 3.10 2.68 0.00 0.62 0.00 0.00 1.71 1.64 0.00 0.93 0.00 0.00 0.00 0.00 0.89 0.00 1.17 2.94 0.00 1.03 0.00 0.00 0.00 0.75 2.12 1.95 2.17 0.00 0.96 0.00 14.77 19.16 15.48 8.05 0.00 0.62 0.91 0.00 356-DM # 1 OK 61 0 0.000 0.126 NaN 0.227 0.229 0 1 0 0 0 1 0 0 1 1 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 1 0 0 2 0 0 0 0 1 1 3 2 0 0 0 0 2 0 4 4 0 1 0 0 2 0 0 5 0 0 1 0 2 0 0 1 1 2 0 0 0 1 0 0 0 0 0 0 1 2 1 0 0 1 0 0 3 3 4 2 0 0 0 0 356-DM mutations/Mb 1 OK 61 0 0.000 0.126 NaN 0.227 0.229 0.00 0.82 0.00 0.00 0.00 1.02 0.00 0.00 0.89 1.06 0.00 0.98 0.00 0.00 1.48 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 3.10 0.00 0.00 0.00 0.00 0.91 0.86 0.00 0.00 1.85 0.00 0.00 0.00 0.00 0.89 1.06 3.50 1.96 0.00 0.00 0.00 0.00 1.86 0.00 4.24 3.90 0.00 1.08 0.00 0.00 5.91 0.00 0.00 13.41 0.00 0.00 0.91 0.00 1.71 0.00 0.00 0.93 1.98 2.05 0.00 0.00 0.00 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.93 1.51 1.06 0.00 0.00 1.08 0.00 0.00 8.86 6.39 12.39 5.36 0.00 0.00 0.00 0.00 40_DM # 1 OK 39 0 0.000 0.068 NaN 0.426 0.429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 5 0 0 0 0 0 5 3 4 0 2 2 0 0 1 0 8 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 2 0 0 0 1 0 0 40_DM mutations/Mb 1 OK 39 0 0.000 0.068 NaN 0.426 0.429 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.82 0.00 4.63 0.00 0.00 0.00 0.00 0.00 5.28 3.50 3.91 0.00 2.05 2.96 0.00 0.00 0.75 0.00 7.81 0.00 0.00 0.00 0.00 2.95 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.02 1.36 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.75 0.00 0.00 0.00 0.00 0.00 0.00 2.95 4.26 0.00 0.00 0.00 0.62 0.00 0.00 41_DM # 1 OK 63 0 0.000 0.066 NaN 0.069 0.073 2 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 1 0 0 0 0 0 1 0 1 0 0 0 1 0 0 1 0 1 1 0 0 0 0 2 1 6 2 0 3 3 2 2 0 2 1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 0 0 0 0 2 2 0 0 0 0 1 0 2 0 0 1 0 0 1 1 1 3 2 8 0 0 0 0 41_DM mutations/Mb 1 OK 63 0 0.000 0.066 NaN 0.069 0.073 1.71 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.89 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.75 0.00 0.00 0.00 0.00 0.00 0.90 0.00 2.13 0.00 0.00 0.00 0.62 0.00 0.00 0.86 0.00 1.28 0.93 0.00 0.00 0.00 0.00 1.78 1.06 7.00 1.96 0.00 3.08 4.44 2.79 1.86 0.00 2.12 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.86 0.82 1.28 0.93 0.00 0.00 0.00 0.00 1.78 2.11 0.00 0.00 0.00 0.00 1.48 0.00 1.86 0.00 0.00 0.98 0.00 0.00 0.96 0.90 2.95 6.39 6.19 21.46 0.00 0.00 0.00 0.00 42_DM # 1 OK 15 0 0.000 0.087 NaN 0.095 NaN 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 0 0 0 0 0 1 1 1 0 2 2 0 0 1 1 0 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42_DM mutations/Mb 1 OK 15 0 0.000 0.087 NaN 0.095 NaN 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.64 1.28 0.93 0.00 0.00 0.00 0.00 0.00 1.06 1.17 0.98 0.00 2.05 2.96 0.00 0.00 0.75 1.06 0.00 0.00 0.00 0.00 1.80 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 43_DM # 1 OK 64 1 0.016 0.274 0.034 0.349 0.417 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 2 0 0 0 1 3 0 0 0 0 0 0 0 4 0 3 2 4 5 1 0 1 0 1 0 1 0 1 1 1 0 2 1 0 2 0 1 1 1 0 1 0 2 2 1 0 0 0 0 0 3 0 1 0 0 0 0 0 3 3 2 4 0 0 0 0 43_DM mutations/Mb 1 OK 64 1 0.016 0.274 0.034 0.349 0.417 0.86 0.00 0.00 0.00 0.00 0.00 0.00 1.26 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.75 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.82 0.00 0.00 0.00 1.28 2.78 0.00 0.00 0.00 0.00 0.00 0.00 0.00 3.91 0.00 3.08 2.96 5.58 4.66 0.75 0.00 0.98 0.00 1.08 0.00 0.90 0.00 2.13 3.10 2.68 0.00 1.25 0.91 0.00 1.71 0.00 1.28 0.93 1.98 0.00 1.36 0.00 1.78 2.11 1.17 0.00 0.00 0.00 0.00 0.00 2.79 0.00 1.06 0.00 0.00 0.00 0.00 0.00 8.86 6.39 6.19 10.73 0.00 0.00 0.00 0.00 48_DM # 1 MAYBE 40 3 0.075 0.070 0.073 0.070 NaN 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4 2 2 0 0 0 0 3 2 4 1 0 1 0 2 0 5 3 2 0 0 1 0 0 3 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 48_DM mutations/Mb 1 MAYBE 40 3 0.075 0.070 0.073 0.070 NaN 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 3.28 2.57 1.85 0.00 0.00 0.00 0.00 2.67 2.11 4.67 0.98 0.00 1.03 0.00 2.79 0.00 3.77 3.18 1.95 0.00 0.00 0.96 0.00 0.00 6.39 6.19 5.36 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.75 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 49_DM # 1 OK 80 1 0.013 0.058 0.058 0.181 0.207 1 1 0 0 0 1 1 0 0 0 1 0 0 0 1 0 1 0 0 1 0 0 0 0 0 0 0 0 1 0 1 0 6 1 2 7 0 0 0 1 1 3 0 3 0 4 2 2 1 4 1 5 0 1 0 0 0 1 1 3 1 0 1 2 0 1 0 0 0 0 0 0 0 0 0 0 1 0 2 0 0 2 0 1 0 0 0 0 4 2 2 1 0 0 0 1 49_DM mutations/Mb 1 OK 80 1 0.013 0.058 0.058 0.181 0.207 0.86 0.82 0.00 0.00 0.00 1.02 1.36 0.00 0.00 0.00 1.17 0.00 0.00 0.00 1.48 0.00 0.93 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.21 0.00 0.91 0.00 5.14 0.82 2.57 6.48 0.00 0.00 0.00 1.26 0.89 3.17 0.00 2.94 0.00 4.10 2.96 2.79 0.93 3.02 1.06 4.88 0.00 1.08 0.00 0.00 0.00 2.13 3.10 8.05 2.21 0.00 0.91 1.83 0.00 0.82 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.86 0.00 2.96 0.00 0.00 1.51 0.00 0.98 0.00 0.00 0.00 0.00 11.82 4.26 6.19 2.68 0.00 0.00 0.00 0.91 50_DM # 1 OK 130 0 0.000 0.073 NaN 0.095 0.113 0 1 0 0 0 1 0 1 3 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 0 2 2 3 3 9 0 0 0 0 2 5 3 2 0 3 2 4 3 2 2 7 0 1 0 1 2 0 4 2 0 2 0 1 3 2 1 0 0 0 0 0 5 0 1 0 1 0 0 0 9 2 1 0 0 2 1 1 4 6 6 7 1 0 1 0 50_DM mutations/Mb 1 OK 130 0 0.000 0.073 NaN 0.095 0.113 0.00 0.82 0.00 0.00 0.00 1.02 0.00 1.26 2.67 0.00 0.00 0.00 0.00 1.03 0.00 0.00 0.00 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 2.13 0.00 0.00 0.00 0.00 0.00 1.83 1.71 2.46 3.85 8.34 0.00 0.00 0.00 0.00 1.78 5.28 3.50 1.96 0.00 3.08 2.96 5.58 2.79 1.51 2.12 6.83 0.00 1.08 0.00 0.90 5.91 0.00 12.39 5.36 0.00 1.25 0.00 0.91 2.57 1.64 1.28 0.00 0.00 0.00 0.00 0.00 4.44 0.00 1.17 0.00 1.86 0.00 0.00 0.00 8.38 1.51 1.06 0.00 0.00 2.15 0.96 0.90 11.82 12.78 18.58 18.78 2.21 0.00 0.91 0.00 51_DM # 1 OK 102 1 0.010 0.070 0.040 0.193 0.282 1 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2 1 1 4 0 2 0 0 3 4 1 6 0 6 0 2 4 2 3 5 0 1 0 0 1 1 1 1 0 6 0 0 1 0 0 3 0 0 0 0 0 2 0 5 0 0 1 0 0 3 1 1 1 1 0 0 3 4 4 7 0 2 1 0 51_DM mutations/Mb 1 OK 102 1 0.010 0.070 0.040 0.193 0.282 0.86 0.00 0.00 0.00 1.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.03 0.00 0.00 0.00 1.51 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.71 0.82 1.28 3.70 0.00 2.05 0.00 0.00 2.67 4.22 1.17 5.87 0.00 6.15 0.00 2.79 3.72 1.51 3.18 4.88 0.00 1.08 0.00 0.00 2.95 2.13 3.10 2.68 0.00 3.75 0.00 0.00 0.86 0.00 0.00 2.78 0.00 0.00 0.00 0.00 0.00 2.11 0.00 4.89 0.00 0.00 1.48 0.00 0.00 2.26 1.06 0.98 2.17 1.08 0.00 0.00 8.86 8.52 12.39 18.78 0.00 1.25 0.91 0.00 58_DM_R # 1 OK 149 1 0.007 0.059 0.058 0.161 0.100 0 1 1 0 1 0 0 2 1 1 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 4 5 3 8 0 0 0 0 2 2 10 14 1 2 1 0 5 6 4 15 0 0 0 0 1 1 1 4 0 0 0 0 1 2 1 4 0 0 3 1 2 0 2 0 0 2 0 0 1 1 0 2 0 1 1 1 3 8 9 4 0 2 0 0 58_DM_R mutations/Mb 1 OK 149 1 0.007 0.059 0.058 0.161 0.100 0.00 0.82 1.28 0.00 1.98 0.00 0.00 2.52 0.89 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.13 0.00 0.00 0.00 0.00 0.00 0.00 3.43 4.10 3.85 7.41 0.00 0.00 0.00 0.00 1.78 2.11 11.67 13.70 1.86 2.05 1.48 0.00 4.66 4.52 4.24 14.64 0.00 0.00 0.00 0.00 2.95 2.13 3.10 10.73 0.00 0.00 0.00 0.00 0.86 1.64 1.28 3.70 0.00 0.00 4.09 1.26 1.78 0.00 2.33 0.00 0.00 2.05 0.00 0.00 0.93 0.75 0.00 1.95 0.00 1.08 0.96 0.90 8.86 17.03 27.87 10.73 0.00 1.25 0.00 0.00 59_DM # 1 OK 74 0 0.000 0.095 NaN 0.129 0.403 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 1 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 1 0 2 1 0 1 0 0 1 4 4 1 0 12 1 2 1 2 1 4 0 0 0 0 0 0 0 2 0 8 0 3 0 1 1 0 1 1 0 0 1 0 2 0 2 1 0 0 0 1 1 0 0 0 0 1 2 1 1 0 1 0 0 0 59_DM mutations/Mb 1 OK 74 0 0.000 0.095 NaN 0.129 0.403 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.89 0.00 0.00 0.00 1.86 0.00 0.00 1.39 0.00 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.62 0.00 0.00 0.86 0.00 2.57 0.93 0.00 1.02 0.00 0.00 0.89 4.22 4.67 0.98 0.00 12.30 1.48 2.79 0.93 1.51 1.06 3.90 0.00 0.00 0.00 0.00 0.00 0.00 0.00 5.36 0.00 5.00 0.00 2.74 0.00 0.82 1.28 0.00 1.98 1.02 0.00 0.00 0.89 0.00 2.33 0.00 3.72 1.03 0.00 0.00 0.00 0.75 1.06 0.00 0.00 0.00 0.00 0.90 5.91 2.13 3.10 0.00 2.21 0.00 0.00 0.00 60_DM # 1 OK 135 1 0.007 0.063 0.045 0.081 0.059 2 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 2 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 2 2 0 7 0 1 0 0 1 1 1 8 0 24 2 4 2 6 3 3 0 0 0 1 1 1 0 1 0 16 1 1 5 3 0 1 1 0 1 0 3 0 0 1 0 0 0 0 3 1 1 0 0 0 0 1 7 1 5 2 0 2 0 0 60_DM mutations/Mb 1 OK 135 1 0.007 0.063 0.045 0.081 0.059 1.71 0.00 1.28 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.86 0.75 0.00 0.00 0.00 0.00 0.00 0.90 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.71 1.64 0.00 6.48 0.00 1.02 0.00 0.00 0.89 1.06 1.17 7.83 0.00 24.61 2.96 5.58 1.86 4.52 3.18 2.93 0.00 0.00 0.00 0.90 2.95 2.13 0.00 2.68 0.00 10.00 0.91 0.91 4.29 2.46 0.00 0.93 1.98 0.00 1.36 0.00 2.67 0.00 0.00 0.98 0.00 0.00 0.00 0.00 2.79 0.75 1.06 0.00 0.00 0.00 0.00 0.90 20.68 2.13 15.48 5.36 0.00 1.25 0.00 0.00 66_DM_R # 1 OK 995 17 0.017 0.179 0.221 0.187 0.200 0 0 0 1 0 1 3 3 0 0 1 2 1 3 1 4 0 0 1 0 1 0 0 0 0 0 0 0 3 5 4 0 4 35 5 12 0 3 3 0 3 9 8 17 1 27 12 5 6 9 12 6 1 2 0 0 4 17 4 3 0 16 4 3 6 6 12 46 6 25 8 14 5 8 7 55 26 33 24 11 6 7 16 25 6 8 3 15 30 82 57 127 10 35 8 3 66_DM_R mutations/Mb 1 OK 995 17 0.017 0.179 0.221 0.187 0.200 0.00 0.00 0.00 0.93 0.00 1.02 4.09 3.78 0.00 0.00 1.17 1.96 1.86 3.08 1.48 5.58 0.00 0.00 1.06 0.00 2.17 0.00 0.00 0.00 0.00 0.00 0.00 0.00 6.62 3.12 3.63 0.00 3.43 28.73 6.42 11.11 0.00 3.07 4.09 0.00 2.67 9.50 9.34 16.63 1.86 27.68 17.78 6.97 5.59 6.79 12.72 5.86 2.17 2.15 0.00 0.00 11.82 36.20 12.39 8.05 0.00 10.00 3.63 2.74 5.14 4.93 15.40 42.60 11.89 25.60 10.91 17.62 4.44 8.45 8.17 53.81 48.41 33.84 35.56 15.34 5.59 5.28 16.96 24.40 12.99 8.61 2.88 13.51 88.64 174.60 176.52 340.65 22.08 21.86 7.26 2.74 67_DM # 1 OK 153 1 0.007 0.279 0.282 0.317 0.389 5 4 1 2 1 1 1 0 2 0 1 0 2 0 1 1 4 0 2 0 0 0 2 0 0 1 1 0 0 0 1 3 4 4 2 4 0 0 1 0 1 3 5 7 0 8 1 1 6 5 1 1 0 1 0 0 2 1 1 1 1 2 0 1 6 2 1 1 0 2 0 1 5 0 3 3 0 0 2 0 3 2 3 2 0 0 1 0 3 4 2 3 1 1 0 2 67_DM mutations/Mb 1 OK 153 1 0.007 0.279 0.282 0.317 0.389 4.29 3.28 1.28 1.85 1.98 1.02 1.36 0.00 1.78 0.00 1.17 0.00 3.72 0.00 1.48 1.39 3.72 0.00 2.12 0.00 0.00 0.00 1.92 0.00 0.00 2.13 3.10 0.00 0.00 0.00 0.91 2.74 3.43 3.28 2.57 3.70 0.00 0.00 1.36 0.00 0.89 3.17 5.84 6.85 0.00 8.20 1.48 1.39 5.59 3.77 1.06 0.98 0.00 1.08 0.00 0.00 5.91 2.13 3.10 2.68 2.21 1.25 0.00 0.91 5.14 1.64 1.28 0.93 0.00 2.05 0.00 1.26 4.44 0.00 3.50 2.94 0.00 0.00 2.96 0.00 2.79 1.51 3.18 1.95 0.00 0.00 0.96 0.00 8.86 8.52 6.19 8.05 2.21 0.62 0.00 1.83 73_DM # 1 OK 89 0 0.000 0.062 NaN 0.084 0.087 1 0 0 0 0 0 1 1 0 0 0 1 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 4 4 0 0 0 0 4 1 1 1 0 0 0 1 1 2 3 1 0 1 0 0 0 0 1 3 0 1 0 3 1 2 0 0 0 0 0 2 0 1 1 1 2 1 0 0 0 1 1 0 0 0 1 0 5 7 6 16 0 0 1 0 73_DM mutations/Mb 1 OK 89 0 0.000 0.062 NaN 0.084 0.087 0.86 0.00 0.00 0.00 0.00 0.00 1.36 1.26 0.00 0.00 0.00 0.98 0.00 1.03 0.00 0.00 0.00 0.00 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.62 0.00 0.00 0.86 0.00 5.13 3.70 0.00 0.00 0.00 0.00 3.56 1.06 1.17 0.98 0.00 0.00 0.00 1.39 0.93 1.51 3.18 0.98 0.00 1.08 0.00 0.00 0.00 0.00 3.10 8.05 0.00 0.62 0.00 2.74 0.86 1.64 0.00 0.00 0.00 0.00 0.00 2.52 0.00 1.06 1.17 0.98 3.72 1.03 0.00 0.00 0.00 0.75 1.06 0.00 0.00 0.00 0.96 0.00 14.77 14.91 18.58 42.92 0.00 0.00 0.91 0.00 74_DM # 1 OK 65 1 0.015 0.363 0.257 0.332 0.328 2 1 1 2 0 0 0 0 0 2 0 3 0 0 1 1 0 0 1 0 0 0 0 0 0 0 1 0 0 0 0 1 2 1 0 0 1 0 0 1 1 1 2 0 0 0 0 0 1 1 0 3 0 1 1 1 0 1 1 0 0 1 0 0 1 1 1 2 0 1 0 0 0 0 0 1 0 0 1 0 1 0 0 2 0 0 1 1 3 4 2 6 0 1 0 0 74_DM mutations/Mb 1 OK 65 1 0.015 0.363 0.257 0.332 0.328 1.71 0.82 1.28 1.85 0.00 0.00 0.00 0.00 0.00 2.11 0.00 2.94 0.00 0.00 1.48 1.39 0.00 0.00 1.06 0.00 0.00 0.00 0.00 0.00 0.00 0.00 3.10 0.00 0.00 0.00 0.00 0.91 1.71 0.82 0.00 0.00 1.98 0.00 0.00 1.26 0.89 1.06 2.33 0.00 0.00 0.00 0.00 0.00 0.93 0.75 0.00 2.93 0.00 1.08 0.96 0.90 0.00 2.13 3.10 0.00 0.00 0.62 0.00 0.00 0.86 0.82 1.28 1.85 0.00 1.02 0.00 0.00 0.00 0.00 0.00 0.98 0.00 0.00 1.48 0.00 0.93 0.00 0.00 1.95 0.00 0.00 0.96 0.90 8.86 8.52 6.19 16.09 0.00 0.62 0.00 0.00 75_DM # 1 OK 42 0 0.000 0.369 NaN 0.352 0.369 0 1 0 0 1 0 0 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 0 1 0 1 0 1 0 0 0 0 0 0 0 0 1 0 0 1 1 0 0 0 0 0 1 0 1 0 0 0 0 0 2 0 1 2 0 1 0 0 2 0 2 2 1 0 0 0 0 0 2 5 3 4 0 1 0 0 75_DM mutations/Mb 1 OK 42 0 0.000 0.369 NaN 0.352 0.369 0.00 0.82 0.00 0.00 1.98 0.00 0.00 0.00 0.89 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.86 0.00 0.00 0.00 0.00 1.02 0.00 1.26 0.00 1.06 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.17 0.00 0.00 0.90 2.95 0.00 0.00 0.00 0.00 0.00 0.91 0.00 0.86 0.00 0.00 0.00 0.00 0.00 2.73 0.00 0.89 2.11 0.00 0.98 0.00 0.00 2.96 0.00 1.86 1.51 1.06 0.00 0.00 0.00 0.00 0.00 5.91 10.65 9.29 10.73 0.00 0.62 0.00 0.00 83_DM # 1 OK 49 0 0.000 0.135 NaN 0.148 0.142 2 0 1 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 1 1 2 0 0 0 0 0 1 0 1 3 1 0 0 0 0 0 0 0 0 0 0 0 2 0 0 1 0 0 0 0 0 0 0 1 0 0 0 1 0 0 1 2 0 0 0 0 4 6 7 6 0 0 0 1 83_DM mutations/Mb 1 OK 49 0 0.000 0.135 NaN 0.148 0.142 1.71 0.00 1.28 0.00 0.00 1.02 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.62 0.91 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.89 1.06 2.33 0.00 0.00 0.00 0.00 0.00 0.93 0.00 1.06 2.93 2.17 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.71 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.98 0.00 0.00 0.00 1.39 0.00 0.00 1.06 1.95 0.00 0.00 0.00 0.00 11.82 12.78 21.68 16.09 0.00 0.00 0.00 0.91 91_DM # 1 OK 48 0 0.000 0.070 NaN 0.181 0.089 0 0 0 1 0 2 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 2 1 1 4 0 0 0 0 3 1 2 7 0 0 0 0 2 1 0 2 0 0 0 0 1 0 1 0 0 1 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 1 0 1 1 1 1 0 0 1 0 1 2 1 3 0 0 0 0 91_DM mutations/Mb 1 OK 48 0 0.000 0.070 NaN 0.181 0.089 0.00 0.00 0.00 0.93 0.00 2.05 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.68 0.00 0.00 0.00 0.00 1.71 0.82 1.28 3.70 0.00 0.00 0.00 0.00 2.67 1.06 2.33 6.85 0.00 0.00 0.00 0.00 1.86 0.75 0.00 1.95 0.00 0.00 0.00 0.00 2.95 0.00 3.10 0.00 0.00 0.62 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.26 0.00 0.00 0.00 0.00 0.00 0.00 1.48 0.00 0.93 0.75 1.06 0.98 0.00 0.00 0.96 0.00 2.95 4.26 3.10 8.05 0.00 0.00 0.00 0.00 92_DM # 1 OK 129 0 0.000 0.161 NaN 0.177 0.177 1 0 2 0 0 1 1 1 0 0 0 1 1 0 0 0 1 2 1 1 0 0 1 0 1 1 0 0 0 2 2 2 3 3 3 3 1 0 0 0 1 1 2 1 0 1 0 1 0 2 5 1 1 0 0 0 0 0 0 2 0 0 0 0 2 1 1 3 0 3 3 0 1 1 1 3 1 0 0 0 2 1 1 2 0 1 0 2 6 12 13 14 0 0 1 1 92_DM mutations/Mb 1 OK 129 0 0.000 0.161 NaN 0.177 0.177 0.86 0.00 2.57 0.00 0.00 1.02 1.36 1.26 0.00 0.00 0.00 0.98 1.86 0.00 0.00 0.00 0.93 1.51 1.06 0.98 0.00 0.00 0.96 0.00 2.95 2.13 0.00 0.00 0.00 1.25 1.82 1.83 2.57 2.46 3.85 2.78 1.98 0.00 0.00 0.00 0.89 1.06 2.33 0.98 0.00 1.03 0.00 1.39 0.00 1.51 5.30 0.98 2.17 0.00 0.00 0.00 0.00 0.00 0.00 5.36 0.00 0.00 0.00 0.00 1.71 0.82 1.28 2.78 0.00 3.07 4.09 0.00 0.89 1.06 1.17 2.94 1.86 0.00 0.00 0.00 1.86 0.75 1.06 1.95 0.00 1.08 0.00 1.80 17.73 25.55 40.26 37.55 0.00 0.00 0.91 0.91 93_DM # 1 OK 85 0 0.000 0.258 NaN 0.315 0.260 4 2 0 0 0 0 0 1 1 0 2 0 0 1 0 0 2 0 1 1 0 0 1 0 0 0 0 0 0 0 0 0 1 0 1 1 0 0 0 0 1 0 0 1 0 0 0 0 1 1 0 2 0 0 0 0 2 0 0 1 0 0 0 0 4 1 1 0 0 1 0 1 4 0 0 1 0 0 0 0 7 1 2 1 0 0 0 1 10 9 4 7 0 0 1 1 93_DM mutations/Mb 1 OK 85 0 0.000 0.258 NaN 0.315 0.260 3.43 1.64 0.00 0.00 0.00 0.00 0.00 1.26 0.89 0.00 2.33 0.00 0.00 1.03 0.00 0.00 1.86 0.00 1.06 0.98 0.00 0.00 0.96 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.86 0.00 1.28 0.93 0.00 0.00 0.00 0.00 0.89 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.93 0.75 0.00 1.95 0.00 0.00 0.00 0.00 5.91 0.00 0.00 2.68 0.00 0.00 0.00 0.00 3.43 0.82 1.28 0.00 0.00 1.02 0.00 1.26 3.56 0.00 0.00 0.98 0.00 0.00 0.00 0.00 6.52 0.75 2.12 0.98 0.00 0.00 0.00 0.90 29.55 19.16 12.39 18.78 0.00 0.00 0.91 0.91 94_DM # 1 OK 93 0 0.000 0.094 NaN 0.099 0.213 2 0 0 0 1 0 0 0 1 1 0 0 0 0 1 0 0 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 1 0 3 1 1 0 0 1 2 1 0 2 0 3 2 16 0 1 0 2 0 0 1 1 1 0 0 0 2 5 2 16 1 1 0 1 0 0 0 0 1 2 1 0 0 0 0 0 2 0 0 1 0 0 0 0 4 2 2 3 0 0 0 0 94_DM mutations/Mb 1 OK 93 0 0.000 0.094 NaN 0.099 0.213 1.71 0.00 0.00 0.00 1.98 0.00 0.00 0.00 0.89 1.06 0.00 0.00 0.00 0.00 1.48 0.00 0.00 0.00 0.00 0.00 0.00 1.08 0.00 0.00 0.00 0.00 0.00 2.68 0.00 0.00 0.00 0.00 0.86 0.00 3.85 0.93 1.98 0.00 0.00 1.26 1.78 1.06 0.00 1.96 0.00 3.08 2.96 22.31 0.00 0.75 0.00 1.95 0.00 0.00 0.96 0.90 2.95 0.00 0.00 0.00 4.42 3.12 1.82 14.63 0.86 0.82 0.00 0.93 0.00 0.00 0.00 0.00 0.89 2.11 1.17 0.00 0.00 0.00 0.00 0.00 1.86 0.00 0.00 0.98 0.00 0.00 0.00 0.00 11.82 4.26 6.19 8.05 0.00 0.00 0.00 0.00 95_DM # 1 OK 39 0 0.000 0.330 NaN 0.425 0.377 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 1 3 0 0 0 0 1 1 2 1 0 0 0 0 1 0 1 0 0 0 0 1 1 0 0 1 0 1 0 0 0 0 1 2 0 0 0 0 0 0 1 0 0 1 0 0 4 4 4 1 0 0 0 1 95_DM mutations/Mb 1 OK 39 0 0.000 0.330 NaN 0.425 0.377 0.86 0.00 0.00 0.00 0.00 1.02 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.82 1.28 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.17 2.94 0.00 0.00 0.00 0.00 0.93 0.75 2.12 0.98 0.00 0.00 0.00 0.00 2.95 0.00 3.10 0.00 0.00 0.00 0.00 0.91 0.86 0.00 0.00 0.93 0.00 1.02 0.00 0.00 0.00 0.00 1.17 1.96 0.00 0.00 0.00 0.00 0.00 0.00 1.06 0.00 0.00 1.08 0.00 0.00 11.82 8.52 12.39 2.68 0.00 0.00 0.00 0.91 96_DM # 1 OK 88 2 0.023 0.181 0.138 0.206 0.264 2 1 1 1 0 0 1 0 1 0 1 0 0 0 0 0 4 0 0 1 0 0 0 0 0 0 0 1 0 1 0 0 0 0 4 4 0 0 0 0 1 1 2 4 0 1 0 1 0 4 3 1 1 0 2 0 1 2 1 1 1 0 0 0 0 2 1 1 0 2 0 1 2 1 0 1 0 1 1 0 1 4 1 1 1 0 0 1 2 6 1 4 0 1 1 1 96_DM mutations/Mb 1 OK 88 2 0.023 0.181 0.138 0.206 0.264 1.71 0.82 1.28 0.93 0.00 0.00 1.36 0.00 0.89 0.00 1.17 0.00 0.00 0.00 0.00 0.00 3.72 0.00 0.00 0.98 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.68 0.00 0.62 0.00 0.00 0.00 0.00 5.13 3.70 0.00 0.00 0.00 0.00 0.89 1.06 2.33 3.91 0.00 1.03 0.00 1.39 0.00 3.02 3.18 0.98 2.17 0.00 1.92 0.00 2.95 4.26 3.10 2.68 2.21 0.00 0.00 0.00 0.00 1.64 1.28 0.93 0.00 2.05 0.00 1.26 1.78 1.06 0.00 0.98 0.00 1.03 1.48 0.00 0.93 3.02 1.06 0.98 2.17 0.00 0.00 0.90 5.91 12.78 3.10 10.73 0.00 0.62 0.91 0.91 97_DM # 1 OK 74 0 0.000 0.083 NaN 0.107 0.089 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 1 2 0 0 1 0 0 0 0 0 2 5 0 0 0 0 1 0 2 4 0 0 0 0 0 0 0 3 0 0 0 0 5 1 0 1 0 1 0 0 3 1 1 3 0 0 0 1 2 2 2 1 0 0 0 0 4 6 7 7 0 1 0 0 97_DM mutations/Mb 1 OK 74 0 0.000 0.083 NaN 0.107 0.089 0.00 0.00 0.00 0.00 0.00 1.02 0.00 0.00 0.00 0.00 1.17 0.00 0.00 0.00 0.00 0.00 0.93 0.00 0.00 0.00 0.00 1.08 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.86 1.64 0.00 0.00 1.98 0.00 0.00 0.00 0.00 0.00 2.33 4.89 0.00 0.00 0.00 0.00 0.93 0.00 2.12 3.90 0.00 0.00 0.00 0.00 0.00 0.00 0.00 8.05 0.00 0.00 0.00 0.00 4.29 0.82 0.00 0.93 0.00 1.02 0.00 0.00 2.67 1.06 1.17 2.94 0.00 0.00 0.00 1.39 1.86 1.51 2.12 0.98 0.00 0.00 0.00 0.00 11.82 12.78 21.68 18.78 0.00 0.62 0.00 0.00 98_DM # 1 OK 105 1 0.010 0.086 0.111 0.094 0.128 9 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 9 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 2 0 0 0 0 2 0 0 5 0 0 0 0 1 1 1 2 0 0 0 0 0 1 0 0 0 0 0 0 12 1 0 2 0 1 0 0 9 0 0 0 0 1 0 1 14 1 0 1 0 0 0 2 12 4 4 4 0 0 0 0 98_DM mutations/Mb 1 OK 105 1 0.010 0.086 0.111 0.094 0.128 7.72 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.06 0.00 0.00 0.00 0.00 0.00 0.00 8.38 0.00 0.00 0.00 0.00 0.00 0.00 0.00 2.95 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 1.28 1.85 0.00 0.00 0.00 0.00 1.78 0.00 0.00 4.89 0.00 0.00 0.00 0.00 0.93 0.75 1.06 1.95 0.00 0.00 0.00 0.00 0.00 2.13 0.00 0.00 0.00 0.00 0.00 0.00 10.29 0.82 0.00 1.85 0.00 1.02 0.00 0.00 8.00 0.00 0.00 0.00 0.00 1.03 0.00 1.39 13.04 0.75 0.00 0.98 0.00 0.00 0.00 1.80 35.45 8.52 12.39 10.73 0.00 0.00 0.00 0.00 99_DM # 1 OK 117 0 0.000 0.069 NaN 0.087 0.080 3 1 0 0 0 1 0 0 1 1 1 0 1 2 0 1 1 1 2 1 0 0 0 1 0 0 0 0 0 3 1 1 3 0 5 5 1 1 1 1 0 1 7 2 0 0 0 0 3 3 2 6 0 0 0 0 2 0 3 1 0 0 0 0 0 1 2 1 0 3 0 0 3 2 2 1 0 0 0 0 1 0 2 6 0 0 0 1 3 4 4 6 0 2 1 2 99_DM mutations/Mb 1 OK 117 0 0.000 0.069 NaN 0.087 0.080 2.57 0.82 0.00 0.00 0.00 1.02 0.00 0.00 0.89 1.06 1.17 0.00 1.86 2.05 0.00 1.39 0.93 0.75 2.12 0.98 0.00 0.00 0.00 0.90 0.00 0.00 0.00 0.00 0.00 1.87 0.91 0.91 2.57 0.00 6.42 4.63 1.98 1.02 1.36 1.26 0.00 1.06 8.17 1.96 0.00 0.00 0.00 0.00 2.79 2.26 2.12 5.86 0.00 0.00 0.00 0.00 5.91 0.00 9.29 2.68 0.00 0.00 0.00 0.00 0.00 0.82 2.57 0.93 0.00 3.07 0.00 0.00 2.67 2.11 2.33 0.98 0.00 0.00 0.00 0.00 0.93 0.00 2.12 5.86 0.00 0.00 0.00 0.90 8.86 8.52 12.39 16.09 0.00 1.25 0.91 1.83