feature type start end label R G B shape direction protein Name=PTEN; Synonyms=MMAC1, TEP1; 1 403 Name=PTEN; Synonyms=MMAC1, TEP1; 0.7 0.9 0.9 - - domain Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN. 2 403 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN. 0.69 0.71 0.36 - - domain Required for interaction with NOP53. {ECO:0000269|PubMed:15355975}. 338 348 Required for interaction with NOP53. {ECO:0000269|PubMed:15355975}. 0.6 0.29 0.54 - - domain PDZ domain-binding. 401 403 PDZ domain-binding. 0.35 0.33 0.25 - - mutation Missense_Mutation 171 171 p.Q171E 1.0 1.0 0.0 circle up mutation Frame_Shift_Del 313 313 p.KEYLVLTLTKNDL313fs 1.0 0.0 0.0 square up mutation Splice_Site 70 70 p.L70R 0.6 0.0 0.6 inv_triangle up mutation Frame_Shift_Del 248 248 p.P248fs 1.0 0.0 0.0 square up mutation Frame_Shift_Del 317 317 p.VL317fs 1.0 0.0 0.0 square up mutation Missense_Mutation 75 75 p.H75P 1.0 1.0 0.0 circle up mutation Frame_Shift_Del 242 242 p.E242fs 1.0 0.0 0.0 square up mutation Missense_Mutation 130 130 p.R130Q 1.0 1.0 0.0 circle up