Clinical Features	Time to Death		AGE		GENDER		KARNOFSKY.PERFORMANCE.SCORE		RADIATIONS.RADIATION.REGIMENINDICATION	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q
EGFR	59 (21%)	217	0.59021	1	0.19569	1	0.095622	1	0.33955	1	0.64701	1
TP53	57 (21%)	219	0.28069	1	0.66631	1	1	1	0.10225	1	0.87647	1
PTEN	65 (24%)	211	0.51356	1	0.24	1	0.55688	1	0.24438	1	1	1
PIK3R1	30 (11%)	246	0.77468	1	0.50299	1	0.54786	1	0.56128	1	0.68589	1
RB1	18 (7%)	258	0.40731	1	0.31328	1	1	1	0.018936	1	0.61543	1
NF1	25 (9%)	251	0.81279	1	0.26333	1	1	1	0.44936	1	0.37882	1
IDH1	14 (5%)	262	0.0026053	1	7.9542e-05	0.0686	0.26881	1	0.031866	1	0.002875	1
PIK3CA	24 (9%)	252	0.92485	1	0.67632	1	1	1	0.92238	1	0.37243	1
SPTA1	26 (9%)	250	0.55974	1	0.2283	1	0.14107	1	0.57158	1	0.39559	1
FLG	23 (8%)	253	0.2618	1	0.32583	1	1	1	0.83545	1	0.49364	1
GABRA6	10 (4%)	266	0.8483	1	0.351	1	1	1	0.58042	1	1	1
RPL5	8 (3%)	268	0.89709	1	0.84582	1	0.46951	1	0.88126	1	0.71782	1
KEL	11 (4%)	265	0.79637	1	0.30374	1	1	1	0.15752	1	1	1
RBM47	8 (3%)	268	0.89322	1	0.52538	1	1	1	0.414	1	1	1
PCLO	22 (8%)	254	0.14328	1	0.96736	1	1	1	0.10369	1	0.35054	1
TCHH	14 (5%)	262	0.30684	1	0.27739	1	0.58424	1	0.32181	1	0.39194	1
SEMA3C	9 (3%)	267	0.06156	1	0.74524	1	0.49358	1	0.75066	1	0.28402	1
OR8K3	6 (2%)	270	0.7036	1	0.88202	1	0.42027	1	0.56555	1	0.66817	1
PRB2	5 (2%)	271	0.92833	1	0.17045	1	1	1	0.00075784	0.653	1	1
RYR2	20 (7%)	256	0.84514	1	0.64485	1	0.81094	1	0.086182	1	0.46616	1
TPTE2	7 (3%)	269	0.19091	1	0.9078	1	0.70917	1	0.035612	1	0.69718	1
LZTR1	8 (3%)	268	0.28422	1	0.49588	1	0.26504	1	0.57905	1	0.1313	1
DCAF12L2	6 (2%)	270	0.11738	1	0.97219	1	0.42027	1	0.6293	1	1	1
RIMS2	10 (4%)	266	0.37904	1	0.00133	1	0.098496	1	0.035612	1	1	1
PSPH	5 (2%)	271	0.21866	1	0.36165	1	0.65547	1	0.9145	1	0.6613	1
PDGFRA	9 (3%)	267	0.37758	1	0.063674	1	1	1	0.50698	1	0.28402	1
SPRYD5	5 (2%)	271	0.555	1	0.86228	1	1	1	0.83962	1	1	1
LRFN5	7 (3%)	269	0.02805	1	0.39877	1	0.26374	1	0.32275	1	0.0079747	1
MUC16	34 (12%)	242	0.16603	1	0.92547	1	1	1	0.93895	1	0.70187	1
CALN1	5 (2%)	271	0.15176	1	0.81711	1	1	1	0.66341	1	1	1
HCN1	7 (3%)	269	0.31789	1	0.89728	1	0.26374	1	0.66121	1	0.69718	1
KIF2B	7 (3%)	269	0.27095	1	0.87338	1	0.70917	1	0.2467	1	0.24168	1
AZGP1	4 (1%)	272	0.64355	1	0.84034	1	1	1	NA	NA	1	1
MUC17	16 (6%)	260	0.99695	1	0.8183	1	0.59679	1	0.72534	1	1	1
AFM	6 (2%)	270	0.27127	1	0.39828	1	0.67199	1	0.36272	1	1	1
OR5D13	5 (2%)	271	0.46082	1	0.43442	1	0.65547	1	NA	NA	0.6613	1
DRD5	6 (2%)	270	0.38855	1	0.42518	1	1	1	NA	NA	0.66817	1
SEMG1	6 (2%)	270	0.48669	1	0.09628	1	1	1	0.08863	1	0.18731	1
SULT1B1	5 (2%)	271	0.17393	1	0.63464	1	0.65547	1	0.98137	1	0.6613	1
OR5D18	5 (2%)	271	0.22477	1	0.76755	1	1	1	0.32275	1	0.6613	1
TRPV6	7 (3%)	269	0.70234	1	0.21727	1	0.70917	1	0.47872	1	0.10004	1
POM121L12	5 (2%)	271	0.34704	1	0.21568	1	0.35917	1	0.66121	1	1	1
COL1A2	8 (3%)	268	0.90659	1	0.52821	1	1	1	0.024093	1	0.1313	1
LRRC55	5 (2%)	271	0.074226	1	0.96298	1	0.35917	1	0.11297	1	0.6613	1
CNTNAP2	8 (3%)	268	0.68005	1	0.51591	1	0.054459	1	0.66121	1	0.71782	1
HEATR7B2	9 (3%)	267	0.65487	1	0.27983	1	1	1	0.82088	1	0.28402	1
OR4D5	5 (2%)	271	0.60107	1	0.14337	1	0.16201	1	0.37806	1	0.34577	1
WNT2	5 (2%)	271	0.37644	1	0.23728	1	0.061677	1	0.7165	1	1	1
GABRA1	4 (1%)	272	0.94702	1	0.18896	1	1	1	0.2467	1	1	1
OR5W2	4 (1%)	272	0.32369	1	0.073752	1	0.62515	1	NA	NA	0.30156	1
SLC1A6	6 (2%)	270	0.59496	1	0.80573	1	0.42027	1	0.027109	1	0.66817	1
DOCK5	10 (4%)	266	0.1746	1	0.96728	1	0.3346	1	0.8045	1	0.74268	1
HMCN1	15 (5%)	261	0.62021	1	0.024748	1	0.58332	1	0.63504	1	0.40385	1
STAG2	8 (3%)	268	0.00095345	0.814	0.86598	1	0.46951	1	0.072187	1	0.45514	1
UGT2A3	5 (2%)	271	0.73123	1	0.018598	1	0.65547	1	0.71628	1	0.16691	1
CDKN2C	3 (1%)	273	0.73114	1	0.57643	1	0.30138	1	NA	NA	1	1
REN	5 (2%)	271	0.56477	1	0.96933	1	0.65547	1	0.1464	1	1	1
CDC27	5 (2%)	271	0.20052	1	0.70101	1	0.35917	1	NA	NA	1	1
WBSCR17	5 (2%)	271	0.0013941	1	0.11732	1	0.061677	1	NA	NA	0.051215	1
GRM3	7 (3%)	269	0.72642	1	0.63758	1	0.70917	1	0.44668	1	0.42762	1
FOXG1	3 (1%)	273	0.12674	1	0.6974	1	0.55635	1	NA	NA	1	1
KLF17	5 (2%)	271	0.0021814	1	0.29974	1	0.16201	1	0.44602	1	1	1
SLCO6A1	6 (2%)	270	0.5133	1	0.90959	1	0.42027	1	0.048566	1	0.095233	1
UGT2B28	5 (2%)	271	0.77914	1	0.88914	1	0.65547	1	0.414	1	1	1
HIST1H2BE	3 (1%)	273	0.73175	1	0.19209	1	0.30138	1	0.49977	1	1	1
AP3S1	3 (1%)	273	0.24726	1	0.35093	1	0.30138	1	0.2467	1	0.5538	1
DSG3	7 (3%)	269	0.23257	1	0.96562	1	0.050054	1	0.34227	1	0.69718	1
PROKR2	5 (2%)	271	0.9567	1	0.049487	1	1	1	0.66341	1	0.16691	1
QKI	4 (1%)	272	0.69228	1	0.83615	1	0.62515	1	NA	NA	0.014043	1
TAS2R41	3 (1%)	273	0.87577	1	0.12993	1	0.55635	1	NA	NA	0.27803	1
PCDHA3	7 (3%)	269	0.24709	1	0.27513	1	0.10384	1	0.065878	1	0.69718	1
PAN3	6 (2%)	270	0.28412	1	0.47023	1	1	1	0.76296	1	0.66817	1
COL6A3	12 (4%)	264	0.95771	1	0.26365	1	0.36564	1	0.19232	1	0.35246	1
CYP3A5	5 (2%)	271	0.31342	1	0.69949	1	0.35917	1	0.36272	1	1	1
OR5D16	4 (1%)	272	0.065311	1	0.20464	1	0.62515	1	0.83677	1	1	1
PLCXD3	4 (1%)	272	0.0039007	1	0.72124	1	0.62515	1	NA	NA	0.6121	1
NOX4	5 (2%)	271	0.9956	1	0.4255	1	0.35917	1	0.56555	1	1	1
KLK6	3 (1%)	273	0.24827	1	0.22359	1	0.55635	1	NA	NA	0.5538	1
OR5AR1	3 (1%)	273	0.81744	1	0.075036	1	0.55635	1	0.28589	1	1	1
PODNL1	4 (1%)	272	0.10248	1	0.17449	1	0.62515	1	0.50581	1	0.12276	1
TMPRSS6	6 (2%)	270	0.82766	1	0.20741	1	0.67199	1	0.34227	1	0.66817	1
CALCR	5 (2%)	271	0.043183	1	0.082083	1	0.65547	1	0.66341	1	0.6613	1
PCDHA1	7 (3%)	269	0.60089	1	0.31144	1	0.10384	1	0.98137	1	0.24168	1
ADCY5	6 (2%)	270	0.9902	1	0.34638	1	0.42027	1	NA	NA	0.42227	1
TGFA	3 (1%)	273	0.50122	1	0.47652	1	0.55635	1	NA	NA	1	1
GABRB2	5 (2%)	271	0.52358	1	0.084101	1	0.35917	1	0.32275	1	0.34577	1
ADAMTS16	6 (2%)	270	0.48222	1	0.89446	1	0.42027	1	0.414	1	0.66817	1
POTEH	3 (1%)	273	0.022083	1	0.33422	1	1	1	0.00075836	0.653	0.5538	1
OR52M1	4 (1%)	272	0.96623	1	0.47271	1	1	1	0.74345	1	1	1
BCOR	6 (2%)	270	0.18294	1	0.58532	1	0.67199	1	NA	NA	0.18731	1
PSG1	3 (1%)	273	0.084212	1	0.28287	1	0.55635	1	NA	NA	1	1
TSHZ2	6 (2%)	270	0.44871	1	0.65587	1	0.67199	1	0.6293	1	0.42227	1
FGD5	7 (3%)	269	0.046687	1	0.96156	1	1	1	NA	NA	0.051897	1
CDH18	6 (2%)	270	0.050208	1	0.59152	1	0.42027	1	0.47872	1	0.66817	1
KDELC2	4 (1%)	272	0.55624	1	0.9041	1	0.62515	1	0.54754	1	1	1
TREML2	3 (1%)	273	0.41205	1	0.15769	1	1	1	0.54754	1	0.27803	1
FOXR2	4 (1%)	272	0.12443	1	0.81349	1	0.62515	1	0.71628	1	1	1
ADAM29	6 (2%)	270	0.73395	1	0.0081815	1	0.088966	1	0.00075784	0.653	0.66817	1
DPP10	6 (2%)	270	0.8511	1	0.73728	1	0.67199	1	0.16685	1	1	1
KPRP	5 (2%)	271	0.28106	1	0.95583	1	1	1	0.83962	1	1	1
OR13C5	4 (1%)	272	0.061175	1	0.66932	1	0.14054	1	0.54754	1	0.30156	1
OR5A1	4 (1%)	272	0.83701	1	0.21218	1	0.14054	1	0.9145	1	0.30156	1
SERPINB4	3 (1%)	273	0.50963	1	0.86934	1	0.55635	1	NA	NA	0.27803	1
LUM	4 (1%)	272	0.082607	1	0.85317	1	1	1	0.7649	1	0.6121	1
GNAT3	4 (1%)	272	0.68539	1	0.29501	1	0.30013	1	0.2467	1	0.30156	1
PCDH19	6 (2%)	270	0.61795	1	0.57905	1	0.19591	1	0.66121	1	0.42227	1
OR5M3	4 (1%)	272	0.65873	1	0.31523	1	1	1	0.66121	1	0.6121	1
ALPPL2	4 (1%)	272	0.325	1	0.14109	1	1	1	NA	NA	1	1
RELN	10 (4%)	266	0.47664	1	0.85102	1	1	1	0.83957	1	0.74268	1
MSL3	3 (1%)	273	0.89865	1	0.34235	1	1	1	NA	NA	1	1
GLT1D1	3 (1%)	273	0.41851	1	0.039714	1	1	1	NA	NA	1	1
ABCB1	7 (3%)	269	0.49346	1	0.043163	1	0.26374	1	0.065878	1	0.24168	1
ELTD1	5 (2%)	271	0.90849	1	0.83023	1	0.65547	1	0.11297	1	1	1
TRAT1	3 (1%)	273	0.011072	1	0.083968	1	1	1	NA	NA	0.27803	1
MAGEB4	4 (1%)	272	0.15246	1	0.11375	1	0.14054	1	0.16578	1	1	1
SLC5A7	4 (1%)	272	0.044469	1	0.89604	1	1	1	0.08863	1	1	1
BRAF	3 (1%)	273	0.87886	1	0.047421	1	1	1	0.00075836	0.653	0.27803	1
DAO	4 (1%)	272	0.93285	1	0.97534	1	1	1	0.7649	1	0.6121	1
KRT37	4 (1%)	272	0.94729	1	0.8133	1	1	1	NA	NA	0.12276	1
PRDM9	6 (2%)	270	0.95886	1	0.07092	1	0.67199	1	0.60392	1	1	1
ZNF181	4 (1%)	272	0.37825	1	0.49762	1	0.14054	1	0.2467	1	1	1
IL18RAP	4 (1%)	272	0.94536	1	0.17753	1	0.14054	1	0.28589	1	1	1
POTEG	4 (1%)	272	0.87377	1	0.6456	1	0.14054	1	NA	NA	0.6121	1
PCDH11Y	6 (2%)	270	0.28194	1	0.94849	1	0.088966	1	0.47872	1	0.42227	1
RSPO3	3 (1%)	273	0.39684	1	0.7659	1	0.55635	1	NA	NA	0.27803	1
SEMA3E	5 (2%)	271	0.4304	1	0.41599	1	0.65547	1	0.16578	1	0.16691	1
SLC27A2	5 (2%)	271	0.37407	1	0.29207	1	0.35917	1	0.66121	1	0.6613	1
CKMT1A	3 (1%)	273	0.49056	1	0.042842	1	0.30138	1	0.86148	1	1	1
CYP2D6	4 (1%)	272	0.06034	1	0.20073	1	0.62515	1	NA	NA	0.12276	1
GABRB3	4 (1%)	272	0.93859	1	0.71485	1	0.14054	1	NA	NA	1	1
TAF1L	8 (3%)	268	0.11974	1	0.13742	1	0.028864	1	0.13683	1	0.45514	1
TNFSF9	3 (1%)	273	0.816	1	0.6384	1	0.30138	1	0.54754	1	0.5538	1
ZDHHC4	3 (1%)	273	0.80244	1	0.76351	1	1	1	NA	NA	1	1
FBLN2	5 (2%)	271	0.77305	1	0.017804	1	1	1	0.3482	1	0.6613	1
SYT16	5 (2%)	271	0.36812	1	0.36714	1	0.16201	1	0.11565	1	0.34577	1
F9	4 (1%)	272	0.020273	1	0.55933	1	0.62515	1	NA	NA	1	1
CD33	4 (1%)	272	0.51981	1	0.032759	1	0.14054	1	NA	NA	1	1
CXORF22	6 (2%)	270	0.85618	1	0.49047	1	0.026028	1	0.66121	1	0.66817	1
CARD6	6 (2%)	270	0.029966	1	0.0083946	1	0.42027	1	0.11297	1	0.42227	1
PLEKHG4B	6 (2%)	270	0.36038	1	0.058962	1	0.19591	1	0.71628	1	0.42227	1
CPNE8	4 (1%)	272	0.90131	1	0.8701	1	1	1	NA	NA	0.6121	1
MRGPRE	3 (1%)	273	0.58501	1	0.44675	1	0.04808	1	0.2467	1	0.5538	1
RBMS3	4 (1%)	272	0.55631	1	0.84206	1	0.62515	1	0.85294	1	0.30156	1
NLRP12	6 (2%)	270	0.98547	1	0.47684	1	1	1	0.32275	1	0.18731	1
OR4P4	3 (1%)	273	0.74881	1	0.47675	1	1	1	NA	NA	1	1
SDK1	9 (3%)	267	0.50151	1	0.21542	1	0.49358	1	0.23115	1	0.029547	1
CFHR4	3 (1%)	273	0.57393	1	0.83814	1	0.55635	1	0.71628	1	1	1
DPPA4	3 (1%)	273	0.51483	1	0.55206	1	0.30138	1	0.71628	1	1	1
LPAR3	3 (1%)	273	0.12429	1	0.8475	1	1	1	NA	NA	0.041222	1
FBN3	10 (4%)	266	0.24554	1	0.39349	1	0.50523	1	0.4557	1	1	1
CD1D	3 (1%)	273	0.052685	1	0.23494	1	1	1	0.00075836	0.653	0.5538	1
POTEF	5 (2%)	271	0.97066	1	0.71796	1	1	1	NA	NA	1	1
ACSM2B	4 (1%)	272	0.27625	1	0.377	1	1	1	0.71628	1	0.30156	1
ZNF618	5 (2%)	271	0.066018	1	0.35558	1	1	1	0.50452	1	0.34577	1
FBXL12	3 (1%)	273	0.84405	1	0.71029	1	1	1	NA	NA	1	1
CHD8	7 (3%)	269	0.67752	1	0.424	1	0.26374	1	0.53945	1	0.24168	1
NLRP5	6 (2%)	270	0.98877	1	0.31849	1	0.42027	1	0.28325	1	1	1
OR5P2	3 (1%)	273	0.29475	1	0.32048	1	0.30138	1	0.00075836	0.653	1	1
CLYBL	3 (1%)	273	0.83299	1	0.35591	1	1	1	NA	NA	1	1
MMP13	4 (1%)	272	0.84727	1	0.30706	1	0.62515	1	0.11565	1	0.30156	1
SLCO5A1	4 (1%)	272	0.93118	1	0.72357	1	0.14054	1	NA	NA	0.6121	1
OR4C11	3 (1%)	273	0.48074	1	0.55392	1	1	1	NA	NA	0.27803	1
TRIML1	4 (1%)	272	0.065068	1	0.28267	1	0.14054	1	NA	NA	0.6121	1
FRMD7	5 (2%)	271	0.3548	1	0.52656	1	0.65547	1	0.92055	1	1	1
GRIN2A	7 (3%)	269	0.31937	1	0.61369	1	1	1	0.56555	1	1	1
KCNB2	4 (1%)	272	0.67397	1	0.80025	1	0.62515	1	NA	NA	0.12276	1
SCN9A	8 (3%)	268	0.26307	1	0.53751	1	0.71457	1	0.83962	1	0.1313	1
UGT2B10	4 (1%)	272	0.68483	1	0.26595	1	1	1	0.00075784	0.653	0.6121	1
KDR	6 (2%)	270	0.14001	1	0.79533	1	0.42027	1	0.49826	1	0.66817	1
NDST4	5 (2%)	271	0.93392	1	0.32739	1	0.35917	1	0.089902	1	0.16691	1
PIK3C2G	6 (2%)	270	0.54117	1	0.86909	1	0.67199	1	0.66121	1	0.42227	1
CDH9	5 (2%)	271	0.76349	1	0.87628	1	0.35917	1	NA	NA	0.34577	1
AHNAK2	14 (5%)	262	0.85884	1	0.4458	1	0.042864	1	0.73538	1	0.56916	1
ANO2	5 (2%)	271	4.7462e-09	4.1e-06	0.070217	1	0.061677	1	0.36272	1	0.051215	1
SH3RF2	5 (2%)	271	0.39158	1	0.26782	1	1	1	0.29206	1	0.16691	1
USH2A	14 (5%)	262	0.59847	1	0.64156	1	0.26881	1	0.91803	1	0.086618	1
PCDHB7	4 (1%)	272	0.68613	1	0.25972	1	0.30013	1	0.32018	1	1	1
TLR6	5 (2%)	271	0.74506	1	0.66739	1	0.65547	1	NA	NA	1	1
PAK4	3 (1%)	273	0.8526	1	0.33677	1	0.55635	1	0.7649	1	1	1
PTX4	4 (1%)	272	0.64346	1	0.9825	1	0.62515	1	0.36272	1	0.6121	1
SIGLEC8	3 (1%)	273	0.8614	1	0.15205	1	1	1	0.046894	1	0.27803	1