Stabilization and expansion of the E-cadherin adherens junction
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
adherens junction organization	-0.001	0.085	-9999.0	0.0	-0.212	55.0	55.0
epithelial cell differentiation	0.063	0.053	-9999.0	0.0	-0.133	26.0	26.0
CYFIP2	0.032	0.013	-9999.0	0.0	0.0	76.0	76.0
ENAH	-0.042	0.072	0.257	11.0	-0.274	6.0	17.0
EGFR	0.01	0.017	-9999.0	0.0	0.0	373.0	373.0
EPHA2	0.034	0.012	-9999.0	0.0	0.0	56.0	56.0
MYO6	-0.03	0.049	0.184	9.0	-0.211	12.0	21.0
CTNNB1	0.036	0.007	-9999.0	0.0	0.0	17.0	17.0
ABI1/Sra1/Nap1	0.033	0.066	-9999.0	0.0	-0.126	57.0	57.0
AQP5	-0.018	0.079	0.248	1.0	-0.358	20.0	21.0
CTNND1	0.035	0.01	-9999.0	0.0	0.0	36.0	36.0
mol:PI-4-5-P2	-0.032	0.045	0.174	7.0	-0.199	14.0	21.0
regulation of calcium-dependent cell-cell adhesion	-0.028	0.045	0.183	9.0	-0.189	8.0	17.0
EGF	0.036	0.008	-9999.0	0.0	0.0	25.0	25.0
NCKAP1	0.038	0.003	-9999.0	0.0	0.0	3.0	3.0
AQP3	-0.033	0.093	-9999.0	0.0	-0.334	39.0	39.0
cortical microtubule organization	0.063	0.053	-9999.0	0.0	-0.133	26.0	26.0
GO:0000145	-0.031	0.041	0.157	7.0	-0.19	14.0	21.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin	0.07	0.055	-9999.0	0.0	-0.134	26.0	26.0
MLLT4	0.035	0.01	-9999.0	0.0	0.0	36.0	36.0
ARF6/GDP	-0.053	0.039	-9999.0	0.0	-0.218	12.0	12.0
ARF6	0.035	0.009	-9999.0	0.0	0.0	31.0	31.0
Ephrin A1/EPHA2/NCK1/GIT1	0.075	0.055	-9999.0	0.0	-0.126	25.0	25.0
mol:Ca2+	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
VASP	-0.03	0.083	0.16	1.0	-0.309	32.0	33.0
PVRL2	0.035	0.009	-9999.0	0.0	0.0	31.0	31.0
ZYX	-0.024	0.045	0.178	4.0	-0.212	17.0	21.0
ARF6/GTP	0.078	0.062	-9999.0	0.0	-0.126	24.0	24.0
CDH1	0.035	0.01	-9999.0	0.0	0.0	39.0	39.0
EGFR/EGFR/EGF/EGF	0.0	0.061	-9999.0	0.0	-0.128	67.0	67.0
RhoA/GDP	0.064	0.058	-9999.0	0.0	-0.137	30.0	30.0
actin cytoskeleton organization	-0.027	0.046	0.167	6.0	-0.219	13.0	19.0
IGF-1R heterotetramer	0.034	0.011	-9999.0	0.0	0.0	51.0	51.0
GIT1	0.037	0.004	-9999.0	0.0	0.0	7.0	7.0
IGF1R	0.034	0.011	-9999.0	0.0	0.0	51.0	51.0
IGF1	0.036	0.008	-9999.0	0.0	0.0	25.0	25.0
DIAPH1	-0.113	0.272	-9999.0	0.0	-0.51	142.0	142.0
Wnt receptor signaling pathway	-0.063	0.053	0.133	26.0	-9999.0	0.0	26.0
RHOA	0.036	0.007	-9999.0	0.0	0.0	20.0	20.0
RhoA/GTP	-0.054	0.041	-9999.0	0.0	-0.226	13.0	13.0
CTNNA1	0.036	0.007	-9999.0	0.0	0.0	19.0	19.0
VCL	-0.027	0.047	0.169	6.0	-0.223	13.0	19.0
EFNA1	0.034	0.012	-9999.0	0.0	0.0	53.0	53.0
LPP	-0.031	0.049	0.178	5.0	-0.219	16.0	21.0
Ephrin A1/EPHA2	0.046	0.063	-9999.0	0.0	-0.135	41.0	41.0
SEC6/SEC8	-0.045	0.028	-9999.0	0.0	-0.144	24.0	24.0
MGAT3	-0.029	0.046	0.184	9.0	-0.191	8.0	17.0
HGF/MET	0.036	0.052	-9999.0	0.0	-0.137	19.0	19.0
HGF	0.026	0.018	-9999.0	0.0	0.0	163.0	163.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN	-0.001	0.085	-9999.0	0.0	-0.213	55.0	55.0
actin cable formation	-0.039	0.11	0.346	11.0	-0.307	33.0	44.0
KIAA1543	-0.026	0.035	0.162	6.0	-0.176	8.0	14.0
KIFC3	-0.032	0.042	0.193	5.0	-0.191	8.0	13.0
NCK1	0.036	0.009	-9999.0	0.0	0.0	28.0	28.0
EXOC3	0.036	0.007	-9999.0	0.0	0.0	20.0	20.0
ACTN1	-0.027	0.051	0.187	7.0	-0.21	18.0	25.0
NCK1/GIT1	0.051	0.024	-9999.0	0.0	-0.14	6.0	6.0
mol:GDP	0.063	0.053	-9999.0	0.0	-0.133	26.0	26.0
EXOC4	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
STX4	-0.032	0.047	0.187	7.0	-0.215	11.0	18.0
PIP5K1C	-0.032	0.046	0.176	7.0	-0.201	14.0	21.0
LIMA1	0.032	0.013	-9999.0	0.0	0.0	72.0	72.0
ABI1	0.028	0.017	-9999.0	0.0	0.0	136.0	136.0
ROCK1	-0.034	0.091	0.327	16.0	-0.287	5.0	21.0
adherens junction assembly	-0.024	0.067	0.234	6.0	-0.305	14.0	20.0
IGF-1R heterotetramer/IGF1	0.049	0.063	-9999.0	0.0	-0.144	39.0	39.0
nectin-2(dimer)/I-afadin/I-afadin/nectin-2(dimer/I-afadin/I-afadin	0.049	0.023	-9999.0	0.0	-0.14	3.0	3.0
MET	0.024	0.018	-9999.0	0.0	0.0	184.0	184.0
PLEKHA7	-0.029	0.03	0.055	20.0	-0.127	26.0	46.0
mol:GTP	0.072	0.054	-9999.0	0.0	-0.126	25.0	25.0
establishment of epithelial cell apical/basal polarity	-0.039	0.058	0.194	4.0	-0.235	7.0	11.0
cortical actin cytoskeleton stabilization	-0.001	0.085	-9999.0	0.0	-0.212	55.0	55.0
regulation of cell-cell adhesion	-0.027	0.046	0.167	6.0	-0.219	13.0	19.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN/cortical actin cytoskeleton	-0.001	0.085	-9999.0	0.0	-0.213	55.0	55.0