Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.015 0.094 0.283 13.0 -9999.0 0.0 13.0 KIRREL -0.002 0.12 -9999.0 0.0 -0.389 13.0 13.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.015 0.094 -9999.0 0.0 -0.283 13.0 13.0 PLCG1 0.028 0.035 -9999.0 0.0 -0.38 1.0 1.0 ARRB2 0.033 0.005 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.024 0.016 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.044 0.086 -9999.0 0.0 -0.214 13.0 13.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.004 0.056 -9999.0 0.0 -0.21 9.0 9.0 FYN -0.017 0.076 0.164 11.0 -0.204 13.0 24.0 mol:Ca2+ 0.039 0.09 -9999.0 0.0 -0.227 13.0 13.0 mol:DAG 0.04 0.091 -9999.0 0.0 -0.228 13.0 13.0 NPHS2 0.02 0.027 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.04 0.091 -9999.0 0.0 -0.228 13.0 13.0 regulation of endocytosis 0.031 0.075 -9999.0 0.0 -0.196 13.0 13.0 Nephrin/NEPH1/podocin/Cholesterol 0.029 0.078 -9999.0 0.0 -0.209 13.0 13.0 establishment of cell polarity 0.015 0.094 -9999.0 0.0 -0.283 13.0 13.0 Nephrin/NEPH1/podocin/NCK1-2 0.061 0.088 -9999.0 0.0 -0.199 13.0 13.0 Nephrin/NEPH1/beta Arrestin2 0.033 0.076 -9999.0 0.0 -0.198 13.0 13.0 NPHS1 0.021 0.027 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin 0.028 0.074 -9999.0 0.0 -0.205 13.0 13.0 TJP1 0.033 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.033 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.033 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.042 0.091 -9999.0 0.0 -0.229 13.0 13.0 CD2AP 0.033 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.048 0.084 -9999.0 0.0 -0.214 12.0 12.0 GRB2 0.033 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.031 0.093 0.168 12.0 -0.208 22.0 34.0 cytoskeleton organization -0.015 0.06 0.197 1.0 -0.233 8.0 9.0 Nephrin/NEPH1 0.017 0.066 -9999.0 0.0 -0.192 13.0 13.0 Nephrin/NEPH1/ZO-1 0.033 0.083 -9999.0 0.0 -0.226 13.0 13.0