Clinical Features Time to Death AGE GENDER KARNOFSKY.PERFORMANCE.SCORE HISTOLOGICAL.TYPE PATHOLOGY.T PATHOLOGY.N PATHOLOGICSPREAD(M) TUMOR.STAGE RADIATIONS.RADIATION.REGIMENINDICATION NEOADJUVANT.THERAPY NUMBERPACKYEARSSMOKED STOPPEDSMOKINGYEAR TOBACCOSMOKINGHISTORYINDICATOR YEAROFTOBACCOSMOKINGONSET nCNV (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q Chi-square test_P Chi-square test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q t-test_P t-test_Q Amp Peak 1(1p22.3) 65 (29%) 158 0.19444 1 0.00054709 0.546 0.88315 1 0.55333 1 0.40933 1 0.66455 1 0.47109 1 0.8055 1 0.66416 1 0.38065 1 0.10754 1 0.7327 1 0.9197 1 0.76734 1 0.92546 1 Amp Peak 2(1q21.3) 167 (75%) 56 0.76323 1 0.056051 1 0.044023 1 0.34358 1 0.075665 1 0.4101 1 0.3147 1 0.56433 1 0.94655 1 0.3668 1 0.29328 1 0.46543 1 0.35401 1 0.10353 1 0.32572 1 Amp Peak 3(3p11.1) 27 (12%) 196 0.80498 1 0.82486 1 0.21866 1 NA NA 0.66098 1 0.027072 1 0.18918 1 1 1 0.16703 1 1 1 0.77997 1 0.035066 1 0.27092 1 0.07767 1 0.29571 1 Amp Peak 4(3q26.2) 69 (31%) 154 0.44469 1 0.092205 1 0.5602 1 0.73592 1 0.88754 1 0.41778 1 0.97788 1 0.65742 1 0.71944 1 0.40335 1 1 1 0.19952 1 0.29583 1 0.10968 1 0.22637 1 Amp Peak 5(5p15.33) 145 (65%) 78 0.42004 1 0.0065058 1 0.034097 1 0.016809 1 0.39853 1 0.054994 1 0.94014 1 1 1 0.83382 1 0.26915 1 0.70305 1 0.238 1 0.14186 1 0.35716 1 0.41189 1 Amp Peak 6(5p13.2) 132 (59%) 91 0.0507 1 0.022362 1 0.029283 1 0.48818 1 0.63769 1 0.037804 1 0.68994 1 0.45886 1 0.44427 1 0.28905 1 0.58241 1 0.15357 1 0.091073 1 0.57278 1 0.67825 1 Amp Peak 7(6p21.1) 78 (35%) 145 0.92198 1 0.29085 1 0.39715 1 0.65121 1 0.82231 1 0.08549 1 0.55812 1 0.12457 1 0.82043 1 1 1 0.44544 1 0.8344 1 0.7334 1 0.0080999 1 0.28923 1 Amp Peak 8(7p21.1) 124 (56%) 99 0.39828 1 0.068578 1 0.41533 1 0.96737 1 0.71861 1 0.46374 1 0.0097942 1 0.89911 1 0.44298 1 0.7932 1 0.19936 1 0.509 1 0.92308 1 0.11404 1 0.23261 1 Amp Peak 9(7p11.2) 117 (52%) 106 0.19025 1 0.047077 1 0.58915 1 0.67085 1 0.64367 1 0.30093 1 0.0019157 1 0.62692 1 0.22724 1 0.7903 1 0.71882 1 0.48591 1 0.97867 1 0.25915 1 0.041991 1 Amp Peak 10(7q31.2) 88 (39%) 135 0.66054 1 0.029842 1 0.68027 1 0.70551 1 0.29616 1 0.4835 1 0.085982 1 0.29827 1 0.32137 1 0.5916 1 0.8527 1 0.61413 1 0.75044 1 0.45535 1 0.78483 1 Amp Peak 11(8p11.21) 63 (28%) 160 0.61024 1 0.10814 1 0.5496 1 NA NA 0.43677 1 0.40662 1 0.26147 1 0.62077 1 0.2527 1 0.3723 1 0.69145 1 0.68938 1 0.15794 1 0.17483 1 0.99532 1 Amp Peak 12(8p11.21) 68 (30%) 155 0.27647 1 0.013514 1 0.56016 1 NA NA 0.43501 1 0.73391 1 0.2651 1 1 1 0.48675 1 0.39813 1 0.32304 1 0.61002 1 0.45897 1 0.023581 1 0.67261 1 Amp Peak 13(8q11.1) 95 (43%) 128 0.54364 1 0.015641 1 0.8918 1 0.62958 1 0.24749 1 0.39022 1 0.28599 1 0.80237 1 0.43072 1 0.42575 1 0.026353 1 0.80335 1 0.32647 1 0.0024763 1 0.12917 1 Amp Peak 14(8q24.21) 146 (65%) 77 0.14831 1 0.039619 1 0.57209 1 0.99471 1 0.036506 1 0.38381 1 0.51267 1 0.88969 1 0.68111 1 0.093501 1 0.5693 1 0.60959 1 0.11677 1 0.042464 1 0.82485 1 Amp Peak 15(11q13.3) 74 (33%) 149 0.49671 1 0.00020403 0.204 0.56675 1 0.41268 1 0.47369 1 0.95471 1 0.72189 1 0.78286 1 0.48811 1 0.77812 1 1 1 0.84296 1 0.13932 1 0.0084541 1 0.82614 1 Amp Peak 16(12p12.1) 74 (33%) 149 0.0082416 1 0.7048 1 0.39008 1 0.56002 1 0.7788 1 0.28523 1 0.42074 1 0.20952 1 0.84318 1 0.77812 1 1 1 0.70013 1 0.57759 1 0.57614 1 0.24728 1 Amp Peak 17(12q14.1) 67 (30%) 156 0.011926 1 0.52532 1 0.46549 1 0.29219 1 0.82794 1 0.12262 1 0.1617 1 0.95933 1 0.24329 1 1 1 0.84403 1 0.55302 1 0.010165 1 0.15541 1 0.0043114 1 Amp Peak 18(12q15) 68 (30%) 155 0.18808 1 0.70472 1 0.77085 1 0.1986 1 0.81127 1 0.147 1 0.20862 1 1 1 0.48019 1 0.77787 1 0.69559 1 0.13064 1 0.14902 1 0.020327 1 0.0057382 1 Amp Peak 19(14q13.3) 96 (43%) 127 0.58924 1 0.59654 1 0.27748 1 0.6892 1 0.37644 1 0.18974 1 0.98082 1 0.42994 1 0.72964 1 1 1 0.58701 1 0.98983 1 0.3551 1 0.72416 1 0.070087 1 Amp Peak 20(17q12) 99 (44%) 124 0.97077 1 0.43884 1 1 1 0.18705 1 0.46815 1 0.702 1 0.76415 1 0.076621 1 0.5258 1 0.10483 1 0.14803 1 0.30341 1 0.20763 1 0.33474 1 0.97881 1 Amp Peak 21(17q25.3) 110 (49%) 113 0.40995 1 0.043245 1 0.41867 1 0.61866 1 0.62726 1 0.75272 1 0.65785 1 0.024505 1 0.91347 1 0.79453 1 0.27673 1 0.69155 1 0.13493 1 0.33441 1 0.2098 1 Amp Peak 22(18q11.2) 48 (22%) 175 0.22366 1 0.68806 1 0.25053 1 0.81769 1 0.28838 1 1 1 0.61008 1 0.95201 1 0.94078 1 0.534 1 1 1 0.69962 1 0.61544 1 0.43397 1 0.42432 1 Amp Peak 23(19q13.11) 58 (26%) 165 0.49119 1 0.90892 1 0.1706 1 NA NA 0.5513 1 0.87524 1 0.44581 1 0.79709 1 0.679 1 1 1 0.21379 1 0.32377 1 0.11847 1 0.43109 1 0.24555 1 Amp Peak 24(20p11.21) 82 (37%) 141 0.52758 1 0.55126 1 0.40546 1 0.11146 1 0.47794 1 0.23534 1 0.056501 1 0.76307 1 0.1332 1 1 1 0.058922 1 0.98299 1 0.98605 1 0.15325 1 0.36337 1 Amp Peak 25(20q13.2) 96 (43%) 127 0.95954 1 0.44315 1 0.6832 1 0.011635 1 0.19817 1 0.29401 1 0.29777 1 0.21816 1 0.079669 1 0.5911 1 0.26998 1 0.54666 1 0.25127 1 0.067015 1 0.90429 1 Amp Peak 26(20q13.33) 104 (47%) 119 0.5223 1 0.64969 1 0.68605 1 0.071813 1 0.50366 1 0.1843 1 0.22821 1 0.016749 1 0.0039549 1 0.42252 1 0.20265 1 0.75504 1 0.32086 1 0.46116 1 0.6648 1 Amp Peak 27(Xq28) 68 (30%) 155 0.40104 1 0.069635 1 0.14496 1 0.089852 1 0.46787 1 0.24217 1 0.23319 1 0.84306 1 0.2639 1 0.77787 1 0.24077 1 0.013385 1 0.51711 1 0.018373 1 0.78004 1 Del Peak 1(1p36.13) 54 (24%) 169 0.056806 1 0.96304 1 0.027387 1 0.55314 1 0.90194 1 0.06284 1 0.07018 1 0.95305 1 0.29159 1 0.76219 1 0.29382 1 0.57436 1 0.8742 1 0.80058 1 0.95873 1 Del Peak 2(1p12) 65 (29%) 158 0.75801 1 0.12729 1 0.65921 1 0.56082 1 0.16639 1 0.86174 1 1 1 0.62276 1 0.6251 1 1 1 0.84296 1 0.041157 1 0.36331 1 0.84202 1 0.24555 1 Del Peak 3(2q22.1) 21 (9%) 202 0.45072 1 0.51872 1 1 1 NA NA 0.038454 1 0.26785 1 0.50195 1 0.4641 1 0.47401 1 0.63895 1 0.75475 1 0.73688 1 0.095162 1 0.12823 1 0.91846 1 Del Peak 4(2q37.3) 35 (16%) 188 0.84861 1 0.82183 1 0.26629 1 0.52536 1 0.16923 1 0.89887 1 0.33737 1 0.33017 1 0.5945 1 0.4761 1 0.61631 1 0.94985 1 0.43845 1 0.29254 1 0.5448 1 Del Peak 5(3q11.1) 68 (30%) 155 0.51441 1 0.61142 1 1 1 0.06092 1 0.66084 1 0.91484 1 0.80188 1 0.84645 1 0.80367 1 1 1 0.84375 1 0.067541 1 0.50186 1 0.68281 1 0.027132 1 Del Peak 6(3q28) 67 (30%) 156 0.43472 1 0.05195 1 0.30679 1 0.20969 1 0.87579 1 0.88371 1 0.31428 1 0.29509 1 0.15815 1 0.56155 1 0.42864 1 0.76004 1 0.86933 1 0.87737 1 0.36128 1 Del Peak 7(4p15.31) 45 (20%) 178 0.62901 1 0.09004 1 0.40251 1 0.61163 1 0.26633 1 0.81718 1 0.7838 1 0.94921 1 0.6193 1 0.19167 1 0.65595 1 0.18969 1 0.0027725 1 0.098877 1 0.14032 1 Del Peak 8(4q35.2) 76 (34%) 147 0.24057 1 0.60274 1 0.32202 1 0.17411 1 0.43768 1 0.27177 1 0.47434 1 0.13329 1 0.48265 1 0.3974 1 0.25176 1 0.41362 1 0.16677 1 0.27607 1 0.44067 1 Del Peak 9(5q11.1) 58 (26%) 165 0.62712 1 0.070465 1 0.75861 1 0.22896 1 0.25583 1 0.61283 1 0.4959 1 1 1 0.48249 1 0.36438 1 0.83632 1 0.14681 1 0.0042722 1 0.13226 1 0.90212 1 Del Peak 10(5q11.2) 76 (34%) 147 0.74238 1 0.035799 1 1 1 0.3381 1 0.6725 1 0.71922 1 0.10562 1 0.67274 1 0.42735 1 0.77865 1 0.56574 1 0.18324 1 0.0033225 1 0.14653 1 0.27163 1 Del Peak 11(5q31.1) 89 (40%) 134 0.51034 1 0.0021755 1 0.67964 1 0.3381 1 0.39995 1 0.63994 1 0.062263 1 0.86216 1 0.061511 1 0.41396 1 1 1 0.084334 1 0.0056735 1 0.0029728 1 0.12216 1 Del Peak 12(6q11.1) 62 (28%) 161 0.061868 1 0.49119 1 0.22971 1 0.26452 1 0.45652 1 0.93119 1 0.096988 1 0.1366 1 0.018874 1 0.56717 1 1 1 0.091075 1 0.52661 1 0.0371 1 0.11581 1 Del Peak 13(6q22.31) 117 (52%) 106 0.95515 1 0.47845 1 0.89327 1 0.13747 1 0.69703 1 0.6962 1 0.81106 1 0.89794 1 0.41257 1 1 1 0.85573 1 0.72972 1 0.028575 1 0.13755 1 0.35737 1 Del Peak 14(6q26) 116 (52%) 107 0.96273 1 0.42538 1 0.18039 1 0.18738 1 0.39398 1 0.85446 1 0.54347 1 0.83677 1 0.4276 1 1 1 0.36479 1 0.35059 1 0.14098 1 0.23853 1 0.44094 1 Del Peak 15(8p23.2) 104 (47%) 119 0.24073 1 0.49297 1 0.079463 1 0.027709 1 0.070358 1 0.40334 1 0.63167 1 0.72352 1 0.85145 1 0.60459 1 0.36353 1 0.39844 1 0.69063 1 0.22132 1 0.45007 1 Del Peak 16(8p21.3) 112 (50%) 111 0.055749 1 0.9479 1 0.031106 1 0.033002 1 0.050309 1 0.58042 1 0.2945 1 0.2625 1 0.76726 1 0.59439 1 0.85588 1 0.020943 1 0.18406 1 0.79628 1 0.66314 1 Del Peak 17(8p11.21) 46 (21%) 177 0.83719 1 0.76625 1 0.019372 1 0.10359 1 0.81425 1 0.26698 1 0.63903 1 0.80186 1 0.70223 1 0.090172 1 0.26353 1 0.63247 1 0.98309 1 0.79838 1 0.5053 1 Del Peak 18(9p23) 128 (57%) 95 0.09457 1 0.097815 1 0.8918 1 0.78612 1 0.41849 1 0.81225 1 0.011421 1 0.10772 1 0.11466 1 1 1 0.58345 1 0.87692 1 0.041976 1 0.077298 1 0.037369 1 Del Peak 19(9p21.3) 134 (60%) 89 0.22939 1 0.059588 1 0.17065 1 0.67052 1 0.82462 1 0.90616 1 0.0058307 1 0.16496 1 0.060469 1 1 1 0.85369 1 0.84216 1 0.0081379 1 0.16736 1 0.10949 1 Del Peak 20(9q21.11) 112 (50%) 111 0.18108 1 0.4874 1 0.78795 1 0.96741 1 0.10696 1 0.49135 1 0.18661 1 0.92997 1 0.14783 1 0.4374 1 0.070964 1 0.20032 1 0.94472 1 0.7687 1 0.89681 1 Del Peak 21(10p15.3) 54 (24%) 169 0.15604 1 0.69428 1 0.0008553 0.853 0.63824 1 0.16031 1 0.13748 1 0.79133 1 0.70149 1 0.97785 1 0.5319 1 0.83488 1 0.32106 1 0.90119 1 0.0065029 1 0.29484 1 Del Peak 22(10q26.3) 62 (28%) 161 0.82656 1 0.92866 1 0.071095 1 0.071813 1 0.8267 1 0.21489 1 0.26276 1 0.70566 1 0.066651 1 0.073444 1 0.54285 1 0.0594 1 0.55664 1 0.15746 1 0.043591 1 Del Peak 23(11q25) 50 (22%) 173 0.21803 1 0.95543 1 0.749 1 0.72178 1 0.74812 1 0.75929 1 0.72238 1 0.48275 1 0.85591 1 0.5302 1 0.27394 1 0.80992 1 0.92457 1 0.29175 1 0.12556 1 Del Peak 24(12p12.3) 60 (27%) 163 0.56962 1 0.55659 1 0.067623 1 0.94023 1 0.50912 1 0.45382 1 0.080665 1 0.25019 1 0.31835 1 0.12646 1 1 1 0.010402 1 0.47164 1 0.1719 1 0.31473 1 Del Peak 25(12q24.33) 62 (28%) 161 0.78988 1 0.81736 1 0.54856 1 0.8486 1 0.013985 1 0.16773 1 0.97673 1 0.30534 1 0.87968 1 0.24545 1 1 1 0.28205 1 0.87931 1 0.14864 1 0.69417 1 Del Peak 26(13q12.11) 115 (52%) 108 0.76032 1 0.097725 1 0.41807 1 0.024623 1 0.13487 1 0.39886 1 0.8921 1 0.21432 1 0.47588 1 0.42748 1 1 1 0.06315 1 0.13939 1 0.24637 1 0.10081 1 Del Peak 27(14q32.33) 64 (29%) 159 0.25002 1 0.97963 1 0.65493 1 0.88977 1 0.35646 1 0.57428 1 0.10992 1 0.8381 1 0.25699 1 0.76848 1 0.16032 1 0.59513 1 0.89466 1 0.43529 1 0.33288 1 Del Peak 28(15q11.2) 122 (55%) 101 0.60903 1 0.17497 1 0.079478 1 0.12489 1 0.028312 1 0.57414 1 0.84206 1 0.60529 1 0.95185 1 0.79103 1 0.46643 1 0.5818 1 0.33301 1 0.11572 1 0.17466 1 Del Peak 29(15q15.2) 122 (55%) 101 0.94133 1 0.28512 1 0.079478 1 0.12489 1 0.0076896 1 0.63063 1 0.75061 1 0.89962 1 1 1 0.42517 1 0.71596 1 0.64882 1 0.71506 1 0.21229 1 0.34228 1 Del Peak 30(16q23.1) 73 (33%) 150 0.76787 1 0.6098 1 0.47245 1 0.48384 1 0.72318 1 0.84712 1 0.67657 1 0.85219 1 0.75603 1 0.5739 1 0.56393 1 0.49442 1 0.29906 1 0.14725 1 0.75112 1 Del Peak 31(17p13.3) 129 (58%) 94 0.12848 1 0.045666 1 0.076512 1 0.58548 1 0.14372 1 0.74315 1 0.98067 1 0.53466 1 0.95935 1 0.42227 1 0.14271 1 0.38503 1 0.34376 1 0.30834 1 0.010533 1 Del Peak 32(17p11.2) 107 (48%) 116 0.086938 1 0.0071512 1 0.18039 1 0.2537 1 0.34893 1 0.1398 1 0.49453 1 0.32784 1 0.87748 1 0.11057 1 0.36479 1 0.85666 1 0.5062 1 0.65014 1 0.066461 1 Del Peak 33(18q21.1) 113 (51%) 110 0.35817 1 0.20574 1 0.22646 1 0.50604 1 0.1388 1 0.23393 1 0.75246 1 0.31835 1 0.55146 1 1 1 1 1 0.76557 1 0.77575 1 0.46064 1 0.28146 1 Del Peak 34(18q21.32) 115 (52%) 108 0.15064 1 0.16776 1 0.14044 1 0.50604 1 0.2527 1 0.22426 1 0.59823 1 0.65225 1 0.79126 1 0.59728 1 1 1 0.74221 1 0.78283 1 0.29271 1 0.32491 1 Del Peak 35(19p13.3) 117 (52%) 106 0.25058 1 0.67822 1 0.00026884 0.269 0.58548 1 0.38994 1 0.11807 1 0.38497 1 0.16477 1 0.21654 1 0.60158 1 0.10033 1 0.79503 1 0.84442 1 0.20582 1 0.56192 1 Del Peak 36(19q13.33) 80 (36%) 143 0.25452 1 0.24569 1 0.1219 1 0.64122 1 0.55972 1 0.28918 1 0.46813 1 0.16985 1 0.26579 1 0.40895 1 0.13218 1 0.76861 1 0.54492 1 0.50421 1 0.38452 1 Del Peak 37(21q11.2) 75 (34%) 148 0.87333 1 0.43484 1 0.15652 1 0.2685 1 0.55016 1 0.48068 1 0.77583 1 0.92519 1 0.26574 1 0.58229 1 0.055083 1 0.0034101 1 0.091476 1 0.16848 1 0.68291 1 Del Peak 38(21q21.3) 72 (32%) 151 0.92766 1 0.65345 1 0.043188 1 0.7098 1 0.80252 1 0.36755 1 0.67657 1 0.88818 1 0.3882 1 0.57046 1 0.081607 1 0.0073196 1 0.049664 1 0.029121 1 0.85913 1 Del Peak 39(22q13.32) 107 (48%) 116 0.35805 1 0.39135 1 0.34458 1 0.26776 1 0.70374 1 0.79821 1 0.3577 1 0.86754 1 0.23991 1 1 1 0.71706 1 0.97424 1 0.88031 1 0.078854 1 0.20886 1 Del Peak 40(Xp22.2) 58 (26%) 165 0.30249 1 0.22403 1 0.093846 1 0.41899 1 0.56671 1 0.76376 1 0.60141 1 0.86678 1 0.47621 1 0.76457 1 0.53532 1 0.54887 1 0.54869 1 0.66248 1 0.5144 1