Clinical Features CN_CNMF METHLYATION_CNMF RPPA_CNMF RPPA_CHIERARCHICAL MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test Fisher's exact test Fisher's exact test Chi-square test Fisher's exact test Fisher's exact test Chi-square test Fisher's exact test TP53 17 (34%) 33 0.229 1 1 0.147 0.00103 0.699 0.0625 0.411 EGFR 10 (20%) 40 0.317 0.634 1 0.851 0.628 0.174 0.406 0.736 CDKN2A 5 (10%) 45 0.307 1 0.804 0.941 0.317 1 0.881 0.538 SMAD4 5 (10%) 45 0.697 0.516 0.586 0.839 1 1 0.509 0.39 KRAS 4 (8%) 46 0.321 0.492 0.586 0.158 0.16 0.0155 0.913 0.704 KEAP1 6 (12%) 44 0.215 1 0.125 0.163 0.363 0.00033 0.257 0.272 CSMD3 10 (20%) 40 0.0169 0.584 0.877 0.217 0.275 1 0.531 0.621 BRAF 5 (10%) 45 1 0.15 1 0.535 1 SPTA1 7 (14%) 43 0.473 1 0.139 0.335 0.183 0.0997 0.344 0.136 STK11 3 (6%) 47 0.406 0.15 0.699 0.722 0.00429 0.386 1 OR4A5 3 (6%) 47 0.406 1 5.24e-05 1 1 0.125 0.373 SETD2 5 (10%) 45 0.489 0.172 0.304 0.541 0.594 0.57 0.335 0.216 CDH10 4 (8%) 46 1 0.758 0.304 0.431 0.0436 0.56 0.532 1 MGAT4C 3 (6%) 47 1 0.586 0.23 0.494 1 0.874 1 U2AF2 3 (6%) 47 0.588 0.845 1 0.477 0.652