Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.12 0.262 0.606 16.0 -9999.0 0.0 16.0 KIRREL -0.044 0.189 -9999.0 0.0 -0.777 5.0 5.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.12 0.263 -9999.0 0.0 -0.608 16.0 16.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.092 0.207 -9999.0 0.0 -0.571 10.0 10.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.047 0.173 -9999.0 0.0 -0.462 10.0 10.0 FYN -0.072 0.201 -9999.0 0.0 -0.541 10.0 10.0 mol:Ca2+ -0.091 0.204 -9999.0 0.0 -0.564 10.0 10.0 mol:DAG -0.092 0.206 -9999.0 0.0 -0.567 10.0 10.0 NPHS2 -0.011 0.029 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 -0.092 0.206 -9999.0 0.0 -0.567 10.0 10.0 regulation of endocytosis -0.08 0.183 -9999.0 0.0 -0.507 10.0 10.0 Nephrin/NEPH1/podocin/Cholesterol -0.094 0.21 -9999.0 0.0 -0.474 16.0 16.0 establishment of cell polarity -0.12 0.262 -9999.0 0.0 -0.606 16.0 16.0 Nephrin/NEPH1/podocin/NCK1-2 -0.084 0.191 -9999.0 0.0 -0.758 4.0 4.0 Nephrin/NEPH1/beta Arrestin2 -0.062 0.195 -9999.0 0.0 -0.515 10.0 10.0 NPHS1 -0.119 0.271 -9999.0 0.0 -0.68 15.0 15.0 Nephrin/NEPH1/podocin -0.084 0.198 -9999.0 0.0 -0.545 10.0 10.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.092 0.207 -9999.0 0.0 -0.571 10.0 10.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.092 0.207 -9999.0 0.0 -0.571 10.0 10.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.108 0.234 -9999.0 0.0 -0.551 13.0 13.0 cytoskeleton organization -0.06 0.22 -9999.0 0.0 -0.587 10.0 10.0 Nephrin/NEPH1 -0.091 0.204 -9999.0 0.0 -0.459 16.0 16.0 Nephrin/NEPH1/ZO-1 -0.099 0.22 -9999.0 0.0 -0.608 10.0 10.0