Clinical Features	Time to Death		AGE		PRIMARY.SITE.OF.DISEASE		GENDER		DISTANT.METASTASIS		LYMPH.NODE.METASTASIS		TUMOR.STAGECODE		NEOPLASM.DISEASESTAGE	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Chi-square test_P	Chi-square test_Q	t-test_P	t-test_Q	Chi-square test_P	Chi-square test_Q
TP53	26 (16%)	135	0.68661	1	0.069992	1	0.22083	1	0.82765	1	0.59027	1	0.096394	1	NA	NA	0.46438	1
BRAF	82 (51%)	79	0.25616	1	0.096304	1	0.126	1	0.74631	1	0.56792	1	0.83492	1	NA	NA	0.63462	1
C15ORF23	11 (7%)	150	0.5792	1	0.66973	1	0.81862	1	0.74748	1	0.96985	1	0.48789	1	NA	NA	0.67913	1
CDKN2A	27 (17%)	134	0.57088	1	0.99489	1	0.67053	1	1	1	0.82555	1	0.7464	1	NA	NA	0.36564	1
NRAS	49 (30%)	112	0.6999	1	0.39373	1	0.45399	1	1	1	0.61802	1	0.90985	1	NA	NA	0.59141	1
OXA1L	5 (3%)	156	0.69515	1	0.61261	1	0.65638	1	1	1	0.99232	1	0.00011977	0.0914	NA	NA	0.47997	1
STK19	10 (6%)	151	0.41464	1	0.33549	1	1	1	0.49964	1	0.97548	1	0.96513	1	NA	NA	0.7597	1
PTEN	13 (8%)	148	0.70296	1	0.23429	1	0.47259	1	0.55116	1	0.00028	0.213	0.83522	1	NA	NA	0.032529	1
RAC1	12 (7%)	149	0.089782	1	0.41537	1	0.57889	1	1	1	0.96985	1	0.89535	1	NA	NA	0.30331	1
IDH1	8 (5%)	153	0.69727	1	0.0048264	1	1	1	0.4659	1	0.98055	1	0.98087	1	NA	NA	0.70329	1
ACSM2B	31 (19%)	130	0.35246	1	0.86125	1	0.087741	1	0.0018267	1	0.77132	1	0.35095	1	NA	NA	0.82163	1
PPP6C	15 (9%)	146	0.0041157	1	0.64684	1	0.64583	1	1	1	0.40178	1	0.048106	1	NA	NA	0.7553	1
LCE1B	9 (6%)	152	0.061943	1	0.74967	1	0.081719	1	0.72558	1	0.98055	1	0.9334	1	NA	NA	0.67445	1
MUC7	11 (7%)	150	0.35953	1	0.00022313	0.17	0.81862	1	0.74748	1	0.96367	1	0.82822	1	NA	NA	0.57643	1
OR51S1	17 (11%)	144	0.66768	1	0.42437	1	0.19695	1	1	1	0.93366	1	0.049636	1	NA	NA	0.20077	1
NAP1L2	17 (11%)	144	0.28971	1	0.051774	1	0.072207	1	0.42634	1	0.92489	1	0.060549	1	NA	NA	0.63527	1
PRB2	24 (15%)	137	0.52842	1	0.0038505	1	0.15819	1	0.037359	1	0.86246	1	0.41236	1	NA	NA	0.28695	1
TAF1A	10 (6%)	151	0.10725	1	0.56977	1	0.89291	1	0.49964	1	0.17903	1	0.73304	1	NA	NA	0.82341	1
HIST1H2AA	7 (4%)	154	0.73444	1	0.97517	1	0.04093	1	0.70763	1	0.98505	1	0.95535	1	NA	NA	0.75089	1
FRG2B	10 (6%)	151	0.63895	1	0.022378	1	0.80828	1	0.49964	1	0.96985	1	0.91574	1	NA	NA	0.56627	1
CDH9	27 (17%)	134	0.24544	1	0.38452	1	0.013227	1	1	1	0.8125	1	0.20433	1	NA	NA	0.090407	1
PRAMEF11	15 (9%)	146	0.034658	1	0.084844	1	0.75056	1	0.78414	1	0.94194	1	0.051333	1	NA	NA	0.85377	1
HBG2	7 (4%)	154	0.48616	1	0.15592	1	0.8542	1	1	1	0.98505	1	0.007215	1	NA	NA	0.75772	1
DDX3X	16 (10%)	145	0.5702	1	0.53819	1	0.54045	1	0.17164	1	0.0045641	1	0.9912	1	NA	NA	0.70414	1
PRB4	18 (11%)	143	0.055541	1	0.12316	1	0.30705	1	0.20518	1	0.43807	1	0.11958	1	NA	NA	0.87411	1
GRXCR1	15 (9%)	146	0.17778	1	0.028638	1	0.51652	1	1	1	0.94194	1	0.78021	1	NA	NA	0.31761	1
HHLA2	12 (7%)	149	0.72344	1	0.30143	1	0.13282	1	1	1	0.96367	1	0.024925	1	NA	NA	0.9079	1
RBM11	11 (7%)	150	0.52627	1	0.19361	1	0.67279	1	0.74748	1	0.22685	1	0.03286	1	NA	NA	0.36702	1
FUT9	17 (11%)	144	0.29143	1	0.035203	1	0.38946	1	0.60224	1	0.91563	1	0.15704	1	NA	NA	0.25562	1
TTN	127 (79%)	34	0.18586	1	0.83739	1	1	1	0.16616	1	0.49625	1	0.35318	1	NA	NA	0.37613	1
HBD	9 (6%)	152	0.088305	1	0.85624	1	0.37644	1	0.72558	1	0.97548	1	0.94547	1	NA	NA	0.34935	1
KIAA1257	7 (4%)	154	0.22013	1	0.33313	1	0.53842	1	0.42422	1	0.99232	1	0.88489	1	NA	NA	0.72925	1
USP17L2	16 (10%)	145	0.92994	1	0.66234	1	0.075878	1	0.17164	1	0.93366	1	0.1449	1	NA	NA	0.11304	1
CADM2	18 (11%)	143	0.43177	1	0.94353	1	0.6219	1	1	1	0.90589	1	0.13561	1	NA	NA	0.40869	1
GFRAL	24 (15%)	137	0.97142	1	0.82019	1	0.17695	1	0.8204	1	0.59027	1	0.12221	1	NA	NA	0.0761	1
OR4N2	19 (12%)	142	0.82364	1	0.36286	1	0.18855	1	0.011247	1	0.076907	1	0.27664	1	NA	NA	0.66258	1
UGT2B15	17 (11%)	144	0.64694	1	0.35961	1	0.77265	1	0.11187	1	0.11696	1	0.12559	1	NA	NA	0.14005	1
UNC119B	3 (2%)	158	0.99895	1	0.37538	1	1	1	1	1	0.99721	1	0.99	1	NA	NA	0.55453	1
RAPGEF5	8 (5%)	153	0.99683	1	0.35962	1	0.10035	1	0.25977	1	0.98898	1	0.00027873	0.212	NA	NA	0.33083	1
C8A	21 (13%)	140	0.49681	1	0.10621	1	1	1	0.090577	1	0.091387	1	0.37987	1	NA	NA	0.4257	1
ANKRD20A4	4 (2%)	157	0.44898	1	0.53122	1	0.77753	1	0.29745	1	0.99506	1	1.6179e-05	0.0124	NA	NA	0.56372	1
ELF5	4 (2%)	157	0.56222	1	0.77507	1	0.60025	1	1	1	0.99721	1	0.27999	1	NA	NA	0.96974	1
SPAG16	13 (8%)	148	0.50132	1	0.75288	1	0.84755	1	0.37667	1	0.96367	1	0.061495	1	NA	NA	0.5822	1
PHGDH	8 (5%)	153	0.7756	1	0.69544	1	0.58799	1	0.027315	1	0.98898	1	0.0021668	1	NA	NA	0.1427	1
COPG2	3 (2%)	158	0.45387	1	0.99708	1	0.72539	1	1	1	0.99721	1	0.99	1	NA	NA	0.044186	1
GML	8 (5%)	153	0.89829	1	0.11374	1	1	1	0.25977	1	0.98505	1	0.74647	1	NA	NA	0.96507	1
TBC1D3B	3 (2%)	158	0.0019848	1	0.40362	1	0.28548	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
TFEC	15 (9%)	146	0.3703	1	0.11087	1	1	1	1	1	0.94194	1	0.005615	1	NA	NA	0.57062	1
TRAT1	11 (7%)	150	0.036877	1	0.54513	1	0.064794	1	0.53329	1	0.96985	1	0.021791	1	NA	NA	0.8597	1
PRR23B	11 (7%)	150	0.20646	1	0.81349	1	0.082454	1	1	1	0.96985	1	0.041967	1	NA	NA	0.90731	1
C9ORF119	5 (3%)	156	0.33311	1	0.33968	1	1	1	0.15912	1	0.99232	1	5.9054e-05	0.0451	NA	NA	0.81709	1
LIN7A	9 (6%)	152	0.64689	1	0.58138	1	0.37644	1	0.48793	1	0.98505	1	0.0070851	1	NA	NA	0.57598	1
PARM1	14 (9%)	147	0.28755	1	0.23382	1	0.28344	1	0.57652	1	0.94971	1	0.0021178	1	NA	NA	0.16672	1
CCK	5 (3%)	156	0.11174	1	0.72453	1	0.65638	1	0.65302	1	0.99506	1	0.024047	1	NA	NA	0.79506	1
TCEB3C	23 (14%)	138	0.33368	1	0.4723	1	0.8645	1	0.15989	1	0.86246	1	0.53269	1	NA	NA	0.4576	1
DEFB118	7 (4%)	154	0.092402	1	0.64027	1	0.74233	1	1	1	0.98505	1	0.0094035	1	NA	NA	0.76191	1
VEGFC	16 (10%)	145	0.92991	1	0.89868	1	0.39439	1	0.58924	1	0.94194	1	0.014239	1	NA	NA	0.33106	1
MARCH11	8 (5%)	153	0.22614	1	0.78945	1	0.20838	1	0.71143	1	0.089504	1	0.015574	1	NA	NA	0.28944	1
ZFP106	6 (4%)	155	0.52423	1	0.00061539	0.466	0.49122	1	0.086413	1	0.98898	1	0.80957	1	NA	NA	0.38172	1
PDE1A	26 (16%)	135	0.66637	1	0.12962	1	0.018657	1	0.65731	1	0.83824	1	0.13649	1	NA	NA	0.70849	1
OR4F6	12 (7%)	149	0.31925	1	0.20241	1	0.9159	1	0.53789	1	0.22685	1	0.086623	1	NA	NA	0.58451	1
CD2	15 (9%)	146	0.3872	1	0.26137	1	0.040603	1	0.78414	1	0.089104	1	0.18156	1	NA	NA	0.4395	1
EIF3D	3 (2%)	158	0.044383	1	0.48065	1	0.72539	1	0.29915	1	0.99721	1	0.97855	1	NA	NA	0.62777	1
MKX	11 (7%)	150	0.37332	1	0.6837	1	0.059278	1	0.74748	1	0.98055	1	0.015574	1	NA	NA	0.042226	1
ARL16	5 (3%)	156	0.2116	1	0.02708	1	0.059171	1	0.65302	1	0.99232	1	0.88489	1	NA	NA	0.15676	1
OR2L3	13 (8%)	148	0.99891	1	0.92797	1	0.22151	1	1	1	0.018895	1	0.056978	1	NA	NA	0.06989	1
DEFB119	6 (4%)	155	0.19042	1	0.1877	1	0.15485	1	1	1	0.99232	1	0.94331	1	NA	NA	0.51298	1
KLHL4	16 (10%)	145	0.067786	1	0.90206	1	0.25235	1	0.58924	1	0.94971	1	0.12366	1	NA	NA	0.59049	1
NR1H4	10 (6%)	151	0.38078	1	0.4483	1	1	1	0.32766	1	0.97548	1	0.0042017	1	NA	NA	0.36341	1
IL32	7 (4%)	154	0.033469	1	0.70243	1	0.53842	1	0.70763	1	0.98505	1	0.83346	1	NA	NA	0.0083185	1
DGAT2L6	9 (6%)	152	0.36839	1	0.34937	1	0.031164	1	1	1	0.97548	1	0.011288	1	NA	NA	0.76212	1
OR8D4	9 (6%)	152	0.03503	1	0.62468	1	0.48242	1	1	1	0.98055	1	0.014006	1	NA	NA	0.96707	1
GRXCR2	12 (7%)	149	0.26782	1	0.95101	1	0.055025	1	1	1	0.96985	1	0.034186	1	NA	NA	0.68341	1
OR5H2	12 (7%)	149	0.29301	1	0.015806	1	1	1	0.76011	1	0.95696	1	0.022954	1	NA	NA	0.51472	1
SIGLEC14	8 (5%)	153	0.72354	1	0.042029	1	0.1179	1	0.027315	1	0.98505	1	0.0094035	1	NA	NA	0.42039	1
ZNF479	15 (9%)	146	0.31348	1	0.26742	1	0.8059	1	0.78414	1	0.36217	1	0.12528	1	NA	NA	0.78463	1
C2	7 (4%)	154	0.48493	1	0.88266	1	0.74233	1	1	1	0.98898	1	0.00017194	0.131	NA	NA	0.34948	1
GH2	10 (6%)	151	0.54715	1	0.48285	1	0.46625	1	0.74724	1	0.98055	1	0.0043173	1	NA	NA	0.05332	1
GK2	21 (13%)	140	0.20552	1	0.72732	1	0.10452	1	1	1	0.8957	1	0.082853	1	NA	NA	0.067863	1
C2ORF40	4 (2%)	157	0.8404	1	0.40361	1	0.063704	1	0.62431	1	0.99721	1	0.97855	1	NA	NA	NA	NA
CXCR2	11 (7%)	150	0.054602	1	0.675	1	0.60634	1	1	1	0.96367	1	0.047198	1	NA	NA	0.26903	1
RPTN	27 (17%)	134	0.25218	1	0.16477	1	0.061959	1	0.51312	1	0.83824	1	0.08462	1	NA	NA	0.045598	1
PRIM2	9 (6%)	152	0.27871	1	0.50008	1	0.29864	1	0.15648	1	0.13244	1	0.0067031	1	NA	NA	0.023865	1
MUM1L1	17 (11%)	144	0.40015	1	0.67451	1	0.4979	1	1	1	0.91563	1	0.080213	1	NA	NA	0.34863	1
TLL1	33 (20%)	128	0.94132	1	0.16852	1	0.2932	1	0.4262	1	0.67371	1	0.14587	1	NA	NA	0.40491	1
PRC1	9 (6%)	152	0.63525	1	0.44485	1	0.55147	1	0.48793	1	0.98055	1	0.71715	1	NA	NA	0.93064	1
GLRB	19 (12%)	142	0.6122	1	0.1891	1	0.03964	1	0.80092	1	0.8957	1	0.24078	1	NA	NA	0.81835	1
AREG	6 (4%)	155	0.49148	1	0.29433	1	0.84018	1	0.6697	1	0.99232	1	0.00034179	0.259	NA	NA	0.45376	1
SPINK13	6 (4%)	155	0.088625	1	0.16768	1	0.84018	1	0.41614	1	0.98898	1	3.8855e-05	0.0297	NA	NA	0.81709	1
ACD	7 (4%)	154	0.91218	1	0.56283	1	0.028581	1	0.42422	1	0.98505	1	0.0044235	1	NA	NA	0.38402	1
C2ORF39	8 (5%)	153	0.58256	1	0.22011	1	1	1	0.71143	1	0.053031	1	0.0070851	1	NA	NA	0.57573	1
RERG	9 (6%)	152	0.66867	1	0.096072	1	0.48242	1	0.48793	1	0.98505	1	0.0015994	1	NA	NA	0.43794	1
TUBB8	8 (5%)	153	0.69104	1	0.35164	1	1	1	0.71143	1	0.98898	1	0.0021668	1	NA	NA	0.69272	1
AGXT2	16 (10%)	145	0.35322	1	0.38601	1	0.2162	1	1	1	0.94194	1	0.11328	1	NA	NA	0.61088	1
C9	12 (7%)	149	0.70491	1	0.67903	1	0.8335	1	0.76011	1	0.96985	1	0.032075	1	NA	NA	0.90125	1
CX3CL1	3 (2%)	158	0.42697	1	0.93811	1	0.46944	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
DEFB112	6 (4%)	155	0.2364	1	0.4618	1	0.033177	1	1	1	0.98898	1	0.0015674	1	NA	NA	0.72685	1
FAM19A1	7 (4%)	154	0.43302	1	0.96406	1	1	1	0.70763	1	0.98898	1	0.75952	1	NA	NA	0.81296	1
LONRF2	13 (8%)	148	0.018196	1	0.88523	1	0.55794	1	0.76977	1	0.97548	1	0.29734	1	NA	NA	0.45789	1
NAP1L4	6 (4%)	155	0.32583	1	0.33969	1	0.84018	1	0.6697	1	0.98898	1	0.62797	1	NA	NA	0.60622	1
OR5J2	11 (7%)	150	0.67266	1	0.75666	1	0.67279	1	0.21301	1	0.97548	1	0.99572	1	NA	NA	0.83253	1
POM121	11 (7%)	150	0.25802	1	0.9838	1	0.33811	1	0.74748	1	0.96985	1	0.037068	1	NA	NA	0.014933	1
RBM22	4 (2%)	157	0.73262	1	0.32678	1	0.60025	1	0.29745	1	0.99506	1	0.98549	1	NA	NA	0.72116	1
SLC10A2	15 (9%)	146	0.4941	1	0.23833	1	0.15403	1	0.78414	1	0.94194	1	0.032034	1	NA	NA	0.08253	1
C4ORF22	8 (5%)	153	0.69303	1	0.54476	1	0.28149	1	0.71143	1	0.98505	1	0.99342	1	NA	NA	0.77078	1
CLEC14A	15 (9%)	146	0.18285	1	0.92602	1	1	1	0.25968	1	0.95696	1	0.030357	1	NA	NA	0.42177	1
GNAI2	4 (2%)	157	0.13271	1	0.53112	1	0.44035	1	0.62431	1	0.99721	1	3.345e-09	2.57e-06	NA	NA	0.57205	1
IGF2BP3	3 (2%)	158	0.85416	1	0.68747	1	0.46944	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
RBM46	11 (7%)	150	0.99844	1	0.13409	1	0.070331	1	0.53329	1	0.96367	1	0.065346	1	NA	NA	0.82881	1
SERPINB4	21 (13%)	140	0.92834	1	0.20859	1	0.3776	1	0.027775	1	0.1211	1	0.3484	1	NA	NA	0.90163	1
SORT1	5 (3%)	156	0.34028	1	0.5997	1	0.059171	1	0.65302	1	0.99232	1	0.6963	1	NA	NA	0.14748	1