Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.009 0.067 0.178 31.0 -9999.0 0.0 31.0 KIRREL 0.004 0.055 -9999.0 0.0 -0.413 4.0 4.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.009 0.067 -9999.0 0.0 -0.179 31.0 31.0 PLCG1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.003 0.052 -9999.0 0.0 -0.21 6.0 6.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.014 0.035 -9999.0 0.0 -0.203 4.0 4.0 FYN 0.0 0.042 -9999.0 0.0 -0.197 4.0 4.0 mol:Ca2+ 0.005 0.047 -9999.0 0.0 -0.2 4.0 4.0 mol:DAG 0.005 0.048 -9999.0 0.0 -0.201 4.0 4.0 NPHS2 -0.001 0.009 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.005 0.048 -9999.0 0.0 -0.201 4.0 4.0 regulation of endocytosis 0.01 0.041 -9999.0 0.0 -0.18 4.0 4.0 Nephrin/NEPH1/podocin/Cholesterol -0.003 0.047 -9999.0 0.0 -0.207 4.0 4.0 establishment of cell polarity -0.009 0.067 -9999.0 0.0 -0.178 31.0 31.0 Nephrin/NEPH1/podocin/NCK1-2 0.014 0.044 -9999.0 0.0 -0.177 4.0 4.0 Nephrin/NEPH1/beta Arrestin2 0.011 0.042 -9999.0 0.0 -0.181 4.0 4.0 NPHS1 -0.022 0.083 -9999.0 0.0 -0.255 27.0 27.0 Nephrin/NEPH1/podocin 0.002 0.042 -9999.0 0.0 -0.197 4.0 4.0 TJP1 0.005 0.06 -9999.0 0.0 -0.41 5.0 5.0 NCK1 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.005 0.048 -9999.0 0.0 -0.202 4.0 4.0 CD2AP 0.01 0.038 -9999.0 0.0 -0.41 2.0 2.0 Nephrin/NEPH1/podocin/GRB2 0.005 0.048 -9999.0 0.0 -0.202 4.0 4.0 GRB2 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.005 0.053 -9999.0 0.0 -0.197 8.0 8.0 cytoskeleton organization 0.015 0.039 -9999.0 0.0 -0.21 4.0 4.0 Nephrin/NEPH1 -0.004 0.045 -9999.0 0.0 -0.198 4.0 4.0 Nephrin/NEPH1/ZO-1 -0.002 0.069 -9999.0 0.0 -0.279 8.0 8.0