Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.005 0.18 0.276 1.0 -0.515 20.0 21.0 MAP3K8 0.023 0.047 0.125 4.0 -0.316 4.0 8.0 FOS -0.013 0.179 0.25 1.0 -0.521 21.0 22.0 PRKCA 0.018 0.063 0.125 3.0 -0.316 8.0 11.0 PTPN7 0.01 0.087 0.125 11.0 -0.316 15.0 26.0 HRAS 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.002 0.109 -9999.0 0.0 -0.316 25.0 25.0 NRAS 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.051 0.017 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.017 0.179 -9999.0 0.0 -0.553 21.0 21.0 MAP2K1 -0.016 0.142 -9999.0 0.0 -0.362 30.0 30.0 ELK1 0.03 0.003 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.018 0.122 -9999.0 0.0 -0.347 26.0 26.0 mol:GTP 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 MAPK1 -0.017 0.181 -9999.0 0.0 -0.542 22.0 22.0 RAF1 -0.021 0.126 -9999.0 0.0 -0.341 29.0 29.0 KRAS 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0