Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.017 0.165 -9999.0 0.0 -0.525 21.0 21.0 MAP3K8 -0.004 0.08 -9999.0 0.0 -0.363 13.0 13.0 FOS -0.028 0.168 -9999.0 0.0 -0.505 24.0 24.0 PRKCA -0.003 0.084 -9999.0 0.0 -0.398 12.0 12.0 PTPN7 -0.03 0.126 -9999.0 0.0 -0.379 32.0 32.0 HRAS 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB -0.048 0.146 -9999.0 0.0 -0.384 44.0 44.0 NRAS 0.014 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.027 0.01 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.028 0.16 -9999.0 0.0 -0.555 20.0 20.0 MAP2K1 -0.026 0.145 -9999.0 0.0 -0.38 37.0 37.0 ELK1 0.014 0.001 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.03 0.137 -9999.0 0.0 -0.365 38.0 38.0 mol:GTP 0.0 0.0 -9999.0 0.0 -0.003 6.0 6.0 MAPK1 -0.028 0.16 -9999.0 0.0 -0.555 20.0 20.0 RAF1 -0.027 0.135 -9999.0 0.0 -0.366 36.0 36.0 KRAS 0.012 0.019 -9999.0 0.0 -0.306 1.0 1.0