Signaling events mediated by the Hedgehog family
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
TGFB2	0.023	0.126	0.253	4.0	-0.463	14.0	18.0
IHH	0.033	0.052	0.18	4.0	-0.131	19.0	23.0
SHH Np/Cholesterol/GAS1	0.016	0.029	-9999.0	0.0	-0.17	5.0	5.0
LRPAP1	0.027	0.006	-9999.0	0.0	-9999.0	0.0	0.0
dorsoventral neural tube patterning	-0.016	0.028	0.169	5.0	-9999.0	0.0	5.0
SMO/beta Arrestin2	0.014	0.134	-9999.0	0.0	-0.391	12.0	12.0
SMO	-0.014	0.122	-9999.0	0.0	-0.389	15.0	15.0
AKT1	-0.004	0.106	-9999.0	0.0	-0.363	13.0	13.0
ARRB2	0.027	0.007	-9999.0	0.0	-9999.0	0.0	0.0
BOC	0.02	0.069	0.149	11.0	-0.318	10.0	21.0
ADRBK1	0.026	0.021	-9999.0	0.0	-0.318	1.0	1.0
heart looping	-0.014	0.121	-9999.0	0.0	-0.384	15.0	15.0
STIL	0.026	0.089	0.188	38.0	-0.247	11.0	49.0
DHH N/PTCH2	0.032	0.08	0.216	3.0	-0.231	20.0	23.0
DHH N/PTCH1	0.026	0.11	0.207	1.0	-0.325	18.0	19.0
PIK3CA	0.023	0.041	-9999.0	0.0	-0.318	4.0	4.0
DHH	0.022	0.089	0.149	30.0	-0.318	15.0	45.0
PTHLH	0.003	0.178	-9999.0	0.0	-0.628	18.0	18.0
determination of left/right symmetry	-0.014	0.121	-9999.0	0.0	-0.384	15.0	15.0
PIK3R1	0.025	0.029	-9999.0	0.0	-0.318	2.0	2.0
skeletal system development	0.003	0.176	-9999.0	0.0	-0.622	18.0	18.0
IHH N/Hhip	0.046	0.045	0.18	7.0	-9999.0	0.0	7.0
DHH N/Hhip	0.04	0.073	0.216	4.0	-0.222	15.0	19.0
mol:Cholesterol	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
heart development	-0.014	0.121	-9999.0	0.0	-0.384	15.0	15.0
pancreas development	0.033	0.032	0.148	20.0	-9999.0	0.0	20.0
HHAT	0.021	0.041	-9999.0	0.0	-0.318	4.0	4.0
PI3K	0.034	0.042	-9999.0	0.0	-0.258	5.0	5.0
EntrezGene:84976	0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
GAS1	0.023	0.037	0.149	1.0	-0.318	3.0	4.0
somite specification	-0.014	0.121	-9999.0	0.0	-0.384	15.0	15.0
SHH Np/Cholesterol/PTCH1	0.012	0.069	0.177	1.0	-0.235	15.0	16.0
SHH Np/Cholesterol/PTCH2	0.017	0.039	0.179	2.0	-0.171	8.0	10.0
SHH Np/Cholesterol/Megalin	-0.002	0.11	0.166	22.0	-0.172	69.0	91.0
SHH	-0.012	0.027	-9999.0	0.0	-0.225	3.0	3.0
catabolic process	0.015	0.1	0.226	1.0	-0.345	18.0	19.0
SMO/Vitamin D3	0.007	0.099	0.251	5.0	-0.282	16.0	21.0
SHH Np/Cholesterol/Hhip	0.017	0.042	0.151	12.0	-0.166	3.0	15.0
LRP2	-0.038	0.186	0.149	81.0	-0.318	82.0	163.0
receptor-mediated endocytosis	-0.031	0.121	0.222	3.0	-0.353	17.0	20.0
SHH Np/Cholesterol/BOC	0.016	0.043	-9999.0	0.0	-0.187	9.0	9.0
SHH Np/Cholesterol/CDO	0.015	0.03	-9999.0	0.0	-0.17	6.0	6.0
mesenchymal cell differentiation	-0.017	0.042	0.165	3.0	-0.149	12.0	15.0
mol:Vitamin D3	0.04	0.098	0.211	40.0	-0.236	15.0	55.0
IHH N/PTCH2	0.038	0.057	0.245	1.0	-0.241	6.0	7.0
CDON	0.022	0.036	-9999.0	0.0	-0.318	3.0	3.0
IHH N/PTCH1	0.026	0.106	0.283	1.0	-0.347	18.0	19.0
Megalin/LRPAP1	-0.012	0.138	-9999.0	0.0	-0.221	81.0	81.0
PTCH2	0.023	0.054	0.149	7.0	-0.318	6.0	13.0
SHH Np/Cholesterol	0.01	0.019	-9999.0	0.0	-0.167	3.0	3.0
PTCH1	0.015	0.1	0.227	1.0	-0.346	18.0	19.0
HHIP	0.033	0.032	0.149	20.0	-9999.0	0.0	20.0