Stabilization and expansion of the E-cadherin adherens junction
Entity	Mean	Std Dev	Mean of Up Perturbations	Number of Up Perturbations	Mean of Down Perturbations	Number of Down Perturbations	Number of Total Perturbations
adherens junction organization	-0.031	0.092	-9999.0	0.0	-0.182	75.0	75.0
epithelial cell differentiation	0.0	0.098	-9999.0	0.0	-0.159	74.0	74.0
CYFIP2	0.013	0.071	0.149	3.0	-0.318	12.0	15.0
ENAH	-0.045	0.068	0.276	2.0	-0.228	5.0	7.0
EGFR	0.025	0.068	0.149	23.0	-0.318	8.0	31.0
EPHA2	0.016	0.065	0.149	2.0	-0.318	10.0	12.0
MYO6	-0.047	0.078	0.199	7.0	-0.158	75.0	82.0
CTNNB1	0.028	0.004	-9999.0	0.0	-9999.0	0.0	0.0
ABI1/Sra1/Nap1	0.041	0.052	-9999.0	0.0	-0.184	12.0	12.0
AQP5	-0.025	0.1	0.439	1.0	-0.401	8.0	9.0
CTNND1	0.028	0.003	-9999.0	0.0	-9999.0	0.0	0.0
mol:PI-4-5-P2	-0.044	0.074	0.198	7.0	-0.154	71.0	78.0
regulation of calcium-dependent cell-cell adhesion	-0.044	0.077	0.221	5.0	-0.158	67.0	72.0
EGF	-0.027	0.142	0.149	21.0	-0.318	52.0	73.0
NCKAP1	0.028	0.002	-9999.0	0.0	-9999.0	0.0	0.0
AQP3	-0.047	0.118	0.383	1.0	-0.336	26.0	27.0
cortical microtubule organization	0.0	0.098	-9999.0	0.0	-0.159	74.0	74.0
GO:0000145	-0.043	0.07	0.186	7.0	-0.147	71.0	78.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin	0.004	0.101	-9999.0	0.0	-0.16	74.0	74.0
MLLT4	0.02	0.042	-9999.0	0.0	-0.318	4.0	4.0
ARF6/GDP	-0.055	0.058	-9999.0	0.0	-0.152	69.0	69.0
ARF6	0.028	0.005	-9999.0	0.0	-9999.0	0.0	0.0
Ephrin A1/EPHA2/NCK1/GIT1	0.052	0.052	-9999.0	0.0	-0.17	10.0	10.0
mol:Ca2+	-0.0	0.0	-9999.0	0.0	-9999.0	0.0	0.0
VASP	-0.034	0.066	0.207	4.0	-0.158	1.0	5.0
PVRL2	0.028	0.003	-9999.0	0.0	-9999.0	0.0	0.0
ZYX	-0.042	0.072	0.207	5.0	-0.156	65.0	70.0
ARF6/GTP	0.056	0.053	-9999.0	0.0	-0.161	10.0	10.0
CDH1	-0.059	0.157	0.149	12.0	-0.318	74.0	86.0
EGFR/EGFR/EGF/EGF	-0.037	0.114	-9999.0	0.0	-0.172	108.0	108.0
RhoA/GDP	0.002	0.096	-9999.0	0.0	-0.154	74.0	74.0
actin cytoskeleton organization	-0.051	0.077	0.183	7.0	-0.162	65.0	72.0
IGF-1R heterotetramer	0.025	0.029	-9999.0	0.0	-0.317	2.0	2.0
GIT1	0.028	0.005	-9999.0	0.0	-9999.0	0.0	0.0
IGF1R	0.025	0.029	-9999.0	0.0	-0.318	2.0	2.0
IGF1	0.012	0.08	0.149	6.0	-0.318	15.0	21.0
DIAPH1	-0.036	0.217	-9999.0	0.0	-0.541	38.0	38.0
Wnt receptor signaling pathway	-0.0	0.098	0.159	74.0	-9999.0	0.0	74.0
RHOA	0.028	0.004	-9999.0	0.0	-9999.0	0.0	0.0
RhoA/GTP	-0.055	0.059	-9999.0	0.0	-0.153	69.0	69.0
CTNNA1	0.027	0.007	-9999.0	0.0	-9999.0	0.0	0.0
VCL	-0.052	0.078	0.185	7.0	-0.165	65.0	72.0
EFNA1	0.026	0.009	-9999.0	0.0	-9999.0	0.0	0.0
LPP	-0.049	0.07	0.199	5.0	-0.153	74.0	79.0
Ephrin A1/EPHA2	-0.009	0.09	-9999.0	0.0	-0.155	73.0	73.0
SEC6/SEC8	-0.048	0.06	-9999.0	0.0	-0.153	66.0	66.0
MGAT3	-0.044	0.078	0.223	5.0	-0.16	67.0	72.0
HGF/MET	-0.024	0.108	-9999.0	0.0	-0.173	88.0	88.0
HGF	0.018	0.073	0.149	14.0	-0.318	11.0	25.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN	-0.032	0.092	-9999.0	0.0	-0.183	75.0	75.0
actin cable formation	-0.018	0.108	0.263	17.0	-0.243	8.0	25.0
KIAA1543	-0.046	0.073	0.188	7.0	-0.151	72.0	79.0
KIFC3	-0.047	0.072	0.217	4.0	-0.156	72.0	76.0
NCK1	0.027	0.006	-9999.0	0.0	-9999.0	0.0	0.0
EXOC3	0.026	0.008	-9999.0	0.0	-9999.0	0.0	0.0
ACTN1	-0.046	0.075	0.202	6.0	-0.156	74.0	80.0
NCK1/GIT1	0.04	0.01	-9999.0	0.0	-9999.0	0.0	0.0
mol:GDP	0.0	0.098	-9999.0	0.0	-0.159	74.0	74.0
EXOC4	0.025	0.01	-9999.0	0.0	-9999.0	0.0	0.0
STX4	-0.045	0.075	0.199	7.0	-0.156	72.0	79.0
PIP5K1C	-0.044	0.075	0.199	7.0	-0.156	71.0	78.0
LIMA1	0.028	0.004	-9999.0	0.0	-9999.0	0.0	0.0
ABI1	0.026	0.009	-9999.0	0.0	-9999.0	0.0	0.0
ROCK1	-0.034	0.098	0.355	6.0	-0.244	2.0	8.0
adherens junction assembly	-0.045	0.084	0.274	3.0	-0.308	6.0	9.0
IGF-1R heterotetramer/IGF1	-0.013	0.099	-9999.0	0.0	-0.16	84.0	84.0
nectin-2(dimer)/I-afadin/I-afadin/nectin-2(dimer/I-afadin/I-afadin	0.033	0.034	-9999.0	0.0	-0.222	4.0	4.0
MET	-0.006	0.106	0.149	8.0	-0.318	28.0	36.0
PLEKHA7	-0.046	0.078	0.199	7.0	-0.158	72.0	79.0
mol:GTP	0.05	0.051	-9999.0	0.0	-0.169	10.0	10.0
establishment of epithelial cell apical/basal polarity	-0.015	0.112	0.237	20.0	-0.271	1.0	21.0
cortical actin cytoskeleton stabilization	-0.031	0.092	-9999.0	0.0	-0.182	75.0	75.0
regulation of cell-cell adhesion	-0.051	0.077	0.183	7.0	-0.162	65.0	72.0
E-cadherin/Ca2+/beta catenin/alpha catenin/p120 catenin/EPLIN/cortical actin cytoskeleton	-0.032	0.092	-9999.0	0.0	-0.183	75.0	75.0