Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.01 0.167 0.297 1.0 -0.468 23.0 24.0 MAP3K8 0.022 0.049 0.149 5.0 -0.318 5.0 10.0 FOS -0.007 0.166 0.263 1.0 -0.485 23.0 24.0 PRKCA 0.018 0.062 0.149 3.0 -0.318 9.0 12.0 PTPN7 0.013 0.083 0.15 12.0 -0.318 15.0 27.0 HRAS 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.001 0.109 0.149 16.0 -0.318 28.0 44.0 NRAS 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.051 0.016 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.009 0.161 -9999.0 0.0 -0.513 22.0 22.0 MAP2K1 -0.013 0.137 -9999.0 0.0 -0.345 36.0 36.0 ELK1 0.029 0.003 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.015 0.117 0.171 2.0 -0.343 28.0 30.0 mol:GTP 0.0 0.0 0.002 1.0 -9999.0 0.0 1.0 MAPK1 -0.011 0.168 -9999.0 0.0 -0.522 23.0 23.0 RAF1 -0.019 0.122 -9999.0 0.0 -0.337 33.0 33.0 KRAS 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0