Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.008 0.072 0.215 10.0 -9999.0 0.0 10.0 KIRREL 0.0 0.067 -9999.0 0.0 -0.375 3.0 3.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.008 0.073 -9999.0 0.0 -0.216 10.0 10.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.003 0.057 -9999.0 0.0 -0.218 4.0 4.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP 0.013 0.04 -9999.0 0.0 -0.203 2.0 2.0 FYN 0.001 0.046 -9999.0 0.0 -0.201 3.0 3.0 mol:Ca2+ 0.005 0.052 -9999.0 0.0 -0.212 3.0 3.0 mol:DAG 0.005 0.052 -9999.0 0.0 -0.213 3.0 3.0 NPHS2 -0.001 0.009 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.005 0.052 -9999.0 0.0 -0.213 3.0 3.0 regulation of endocytosis 0.011 0.045 -9999.0 0.0 -0.184 3.0 3.0 Nephrin/NEPH1/podocin/Cholesterol -0.003 0.051 -9999.0 0.0 -0.149 10.0 10.0 establishment of cell polarity -0.008 0.072 -9999.0 0.0 -0.215 10.0 10.0 Nephrin/NEPH1/podocin/NCK1-2 0.014 0.048 -9999.0 0.0 -0.189 3.0 3.0 Nephrin/NEPH1/beta Arrestin2 0.011 0.046 -9999.0 0.0 -0.186 3.0 3.0 NPHS1 -0.015 0.078 -9999.0 0.0 -0.276 8.0 8.0 Nephrin/NEPH1/podocin 0.002 0.047 -9999.0 0.0 -0.202 3.0 3.0 TJP1 0.009 0.042 -9999.0 0.0 -0.409 1.0 1.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.006 0.052 -9999.0 0.0 -0.214 3.0 3.0 CD2AP 0.009 0.042 -9999.0 0.0 -0.409 1.0 1.0 Nephrin/NEPH1/podocin/GRB2 0.006 0.052 -9999.0 0.0 -0.214 3.0 3.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.005 0.061 -9999.0 0.0 -0.196 6.0 6.0 cytoskeleton organization 0.014 0.044 -9999.0 0.0 -0.21 2.0 2.0 Nephrin/NEPH1 -0.003 0.049 -9999.0 0.0 -0.143 10.0 10.0 Nephrin/NEPH1/ZO-1 0.002 0.063 -9999.0 0.0 -0.24 4.0 4.0