Clinical Features Time to Death AGE GENDER DISTANT.METASTASIS LYMPH.NODE.METASTASIS TUMOR.STAGECODE NEOPLASM.DISEASESTAGE nMutated (%) nWild-Type logrank test_P logrank test_Q t-test_P t-test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Chi-square test_P Chi-square test_Q t-test_P t-test_Q Chi-square test_P Chi-square test_Q BRAF 59 (56%) 46 0.43465 1 0.29839 1 1 1 1 1 0.56405 1 NA NA 0.81666 1 CDKN2A 16 (15%) 89 0.87147 1 0.91932 1 0.77317 1 1 1 0.87139 1 NA NA 0.68598 1 NRAS 29 (28%) 76 0.63476 1 0.26633 1 0.81581 1 0.74419 1 0.72012 1 NA NA 0.94888 1 STK19 7 (7%) 98 0.42429 1 0.59758 1 0.41859 1 1 1 0.997 1 NA NA 0.90889 1 TTN 83 (79%) 22 0.20835 1 0.88819 1 0.44031 1 0.17743 1 0.099661 1 NA NA 0.30085 1 TP53 18 (17%) 87 0.59043 1 0.0015891 0.682 0.39743 1 1 1 0.38611 1 NA NA 0.38292 1 PTEN 11 (10%) 94 0.16343 1 0.1626 1 0.29453 1 0.2293 1 0.9373 1 NA NA 0.15469 1 TPTE 29 (28%) 76 0.61199 1 0.22292 1 0.81581 1 1 1 0.85644 1 NA NA 0.48732 1 PRB4 15 (14%) 90 0.30508 1 0.051213 1 0.221 1 1 1 0.31904 1 NA NA 0.83914 1 CDH9 22 (21%) 83 0.73807 1 0.10223 1 1 1 1 1 0.51686 1 NA NA 0.30893 1 SERPINB4 17 (16%) 88 0.4121 1 0.41684 1 0.090383 1 1 1 0.22557 1 NA NA 0.76811 1 PRB2 19 (18%) 86 0.12446 1 0.0073601 1 0.17531 1 1 1 0.59456 1 NA NA 0.46573 1 TCEB3C 14 (13%) 91 0.46961 1 0.48075 1 0.22321 1 1 1 0.95566 1 NA NA 0.84526 1 ADH1C 17 (16%) 88 0.43777 1 0.038789 1 0.77253 1 1 1 0.063348 1 NA NA 0.23074 1 C15ORF23 7 (7%) 98 0.46869 1 0.77984 1 1 1 1 1 0.79811 1 NA NA 0.9035 1 CCNE2 10 (10%) 95 1.6024e-05 0.00697 0.80449 1 0.47667 1 1 1 0.93866 1 NA NA 0.34409 1 SDR16C5 16 (15%) 89 0.22051 1 0.11435 1 0.77317 1 0.5032 1 0.59724 1 NA NA 0.34219 1 PDE1A 19 (18%) 86 0.7141 1 0.14101 1 1 1 1 1 0.10935 1 NA NA 0.5218 1 TLL1 24 (23%) 81 0.74676 1 0.14353 1 0.7993 1 1 1 0.22354 1 NA NA 0.37328 1 RAC1 7 (7%) 98 0.82956 1 0.52153 1 0.6709 1 1 1 0.92203 1 NA NA 0.67866 1 RERG 8 (8%) 97 0.73446 1 0.030372 1 1 1 1 1 0.031142 1 NA NA 0.30389 1 OR52L1 12 (11%) 93 0.70417 1 0.84531 1 1 1 1 1 0.046855 1 NA NA 0.79944 1 HBD 8 (8%) 97 0.54592 1 0.8584 1 0.69105 1 1 1 0.99233 1 NA NA 0.56183 1 VEGFC 12 (11%) 93 0.50873 1 0.82259 1 1 1 1 1 0.23993 1 NA NA 0.33693 1 BAGE2 7 (7%) 98 0.47785 1 0.20306 1 0.41859 1 0.12603 1 0.00013804 0.0598 NA NA 0.069407 1 OR1N2 13 (12%) 92 0.89687 1 0.72639 1 0.33621 1 1 1 0.22252 1 NA NA 0.68524 1 PPP6C 10 (10%) 95 0.93384 1 0.84315 1 0.7196 1 0.20886 1 0.00023429 0.101 NA NA 0.57994 1 HNF4G 12 (11%) 93 NA NA 0.25877 1 0.10473 1 1 1 0.02306 1 NA NA 0.55926 1 TRAT1 6 (6%) 99 0.0068066 1 0.33127 1 1 1 1 1 0.034908 1 NA NA 0.72108 1 AREG 5 (5%) 100 NA NA 0.44539 1 0.6306 1 1 1 0.0033418 1 NA NA 0.52769 1 ST18 24 (23%) 81 0.6619 1 0.040053 1 0.62134 1 1 1 0.5847 1 NA NA 0.54537 1 TAF1A 8 (8%) 97 0.13486 1 0.8428 1 0.69105 1 0.30081 1 0.6784 1 NA NA 0.73493 1 GRXCR2 9 (9%) 96 0.5678 1 0.45512 1 0.72153 1 1 1 0.086261 1 NA NA 0.4735 1 OR9K2 11 (10%) 94 0.68697 1 0.058035 1 0.50081 1 1 1 0.18574 1 NA NA 0.45653 1 OXA1L 4 (4%) 101 NA NA 0.13559 1 1 1 1 1 0.00030259 0.13 NA NA 0.074789 1 A2BP1 14 (13%) 91 0.6599 1 0.29698 1 0.75362 1 1 1 0.31532 1 NA NA 0.21512 1 HIST1H2AA 5 (5%) 100 NA NA 0.78684 1 0.6306 1 1 1 0.97913 1 NA NA 0.99 1 LILRA1 21 (20%) 84 0.40725 1 0.61834 1 0.29373 1 0.597 1 0.31331 1 NA NA 0.97379 1 LIN7A 8 (8%) 97 0.00022391 0.0967 0.66197 1 1 1 1 1 0.051993 1 NA NA 0.71183 1 VGLL1 3 (3%) 102 NA NA 0.11103 1 0.55334 1 1 1 0.00012043 0.0523 NA NA 0.45148 1 GALNTL5 10 (10%) 95 0.38365 1 0.42834 1 0.27461 1 1 1 0.028032 1 NA NA 0.50297 1 HSD11B1 6 (6%) 99 0.49916 1 0.17674 1 0.35725 1 1 1 0.013101 1 NA NA 0.51386 1 ANKRD20A4 4 (4%) 101 0.2184 1 0.45493 1 0.31687 1 1 1 0.002579 1 NA NA 0.29691 1 GPR141 8 (8%) 97 0.04355 1 0.37457 1 1 1 1 1 0.079948 1 NA NA 0.45168 1 NAP1L2 10 (10%) 95 0.82887 1 0.091874 1 0.7196 1 1 1 0.058617 1 NA NA 0.85456 1 C18ORF26 13 (12%) 92 0.06 1 0.70419 1 0.33621 1 1 1 0.1803 1 NA NA 0.31239 1 DEFB110 5 (5%) 100 0.28015 1 0.96292 1 0.31843 1 1 1 0.002579 1 NA NA 0.37794 1 IDH1 6 (6%) 99 0.96309 1 0.020638 1 0.35725 1 1 1 0.98397 1 NA NA 0.378 1 SNAP91 15 (14%) 90 0.4531 1 0.23815 1 0.221 1 0.5032 1 0.5151 1 NA NA 0.20222 1 CA1 6 (6%) 99 NA NA 0.15209 1 0.66754 1 1 1 0.71246 1 NA NA 0.89115 1 SERPINB11 12 (11%) 93 0.87369 1 0.67491 1 0.016629 1 1 1 0.17713 1 NA NA 0.48811 1 UGT2B15 13 (12%) 92 0.887 1 0.35884 1 0.1021 1 0.39391 1 0.21113 1 NA NA 0.48379 1 ACSM2B 21 (20%) 84 0.50399 1 0.94999 1 0.0061094 1 1 1 0.61374 1 NA NA 0.94588 1 C16ORF78 8 (8%) 97 0.67098 1 0.38297 1 1 1 1 1 0.058535 1 NA NA 0.50665 1 TFEC 10 (10%) 95 0.12846 1 0.15776 1 0.7196 1 1 1 0.001844 0.789 NA NA 0.53254 1 TRHDE 24 (23%) 81 0.27603 1 0.087795 1 0.13424 1 1 1 0.4424 1 NA NA 0.48013 1 OR5AC2 13 (12%) 92 0.32187 1 0.78256 1 0.75092 1 1 1 0.83848 1 NA NA 0.39434 1 CCDC102B 11 (10%) 94 0.46482 1 0.92761 1 1 1 1 1 0.18663 1 NA NA 0.59965 1 GRXCR1 12 (11%) 93 0.50094 1 0.018996 1 1 1 1 1 0.9373 1 NA NA 0.42048 1 OR4M2 13 (12%) 92 0.85842 1 0.0019201 0.82 1 1 1 1 0.47488 1 NA NA 0.53652 1 PLAC8L1 3 (3%) 102 NA NA 0.22551 1 0.55334 1 1 1 0.991 1 NA NA 0.78312 1 POM121 10 (10%) 95 0.054309 1 0.92083 1 0.7196 1 1 1 0.098051 1 NA NA 0.047571 1 RBM11 9 (9%) 96 0.2376 1 0.02723 1 1 1 1 1 0.073277 1 NA NA 0.64441 1 RUNX1T1 16 (15%) 89 0.81421 1 0.12743 1 0.14061 1 1 1 0.3997 1 NA NA 0.98397 1 RGS7 17 (16%) 88 0.33923 1 0.012057 1 1 1 0.26978 1 0.091204 1 NA NA 0.8449 1 CLVS2 11 (10%) 94 0.49602 1 0.44152 1 0.50081 1 1 1 0.14658 1 NA NA 0.84475 1 DEFB118 6 (6%) 99 0.66033 1 0.7151 1 1 1 1 1 0.044637 1 NA NA 0.58872 1 OR52A5 12 (11%) 93 0.22124 1 0.2718 1 1 1 1 1 0.1803 1 NA NA 0.62291 1 SPTLC3 13 (12%) 92 0.68941 1 0.8745 1 1 1 1 1 0.31904 1 NA NA 0.28128 1 ACTL7B 7 (7%) 98 NA NA 0.84816 1 0.41859 1 1 1 1.4908e-05 0.0065 NA NA 0.087436 1 PHGDH 7 (7%) 98 0.58973 1 0.15574 1 0.10174 1 1 1 0.044637 1 NA NA 0.042375 1 RGPD3 18 (17%) 87 0.49374 1 0.0061151 1 0.020399 1 0.57492 1 0.15239 1 NA NA 0.77436 1 WDR12 7 (7%) 98 0.013475 1 0.55159 1 0.10174 1 1 1 0.96985 1 NA NA 0.96808 1 MPP7 13 (12%) 92 0.81635 1 0.1382 1 0.33621 1 0.24961 1 0.32347 1 NA NA 0.66991 1