Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 0.032 0.148 0.256 1.0 -0.436 2.0 3.0 MAP3K8 0.027 0.081 0.185 3.0 -0.346 1.0 4.0 FOS 0.016 0.146 -9999.0 0.0 -0.385 3.0 3.0 PRKCA 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 PTPN7 0.04 0.048 0.186 3.0 -9999.0 0.0 3.0 HRAS 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 PRKCB 0.003 0.117 0.186 2.0 -0.346 3.0 5.0 NRAS 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.049 0.016 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 0.004 0.159 -9999.0 0.0 -0.575 2.0 2.0 MAP2K1 -0.012 0.147 -9999.0 0.0 -0.372 4.0 4.0 ELK1 0.028 0.003 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.017 0.14 -9999.0 0.0 -0.428 3.0 3.0 mol:GTP 0.0 0.001 0.003 1.0 -9999.0 0.0 1.0 MAPK1 0.017 0.124 -9999.0 0.0 -0.581 1.0 1.0 RAF1 -0.007 0.103 -9999.0 0.0 -0.323 3.0 3.0 KRAS 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0