GDAC_CnmfIntegratedPipeline Execution Log 1:09 PM Fri May 3, '13

Running as user: cgaadm_deadline

GDAC_TopgenesforCluster1 expfile file:/xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_MethylationPreprocess/SKCM-BRAF_Hotspot_Mutants/3155607/0.GDAC_MethylationPreprocess.Finished/SKCM-BRAF_Hotspot_Mutants.meth.for_clustering.filtered_data.txt
GDAC_TopgenesforCluster1 selectedgenes 10300
GDAC_NmfConsensusClustering2 k int 2
GDAC_NmfConsensusClustering2 k final 8
GDAC_CNMFselectcluster3 output SKCM-BRAF_Hotspot_Mutants
GDAC_CNMFselectcluster3 inputallexp file:/xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_MethylationPreprocess/SKCM-BRAF_Hotspot_Mutants/3155607/0.GDAC_MethylationPreprocess.Finished/SKCM-BRAF_Hotspot_Mutants.meth.for_clustering.filtered_data.txt
GDAC_CnmfReports4 report methylation
Execution Times:
Submitted: 13:09:31 03-05-13
Completed:
Elapsed: 02 hrs 28 mins 31 secs

step 1. GDAC_TopgenesforCluster [id: 398895] This module can be used to selecte top genes with most variation, convert file to gct format, as well as imput missing value

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00205:35
expfile file:/xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_MethylationPreprocess/SKCM-BRAF_Hotspot_Mutants/3155607/0.GDAC_MethylationPreprocess.Finished/SKCM-BRAF_Hotspot_Mutants.meth.for_clustering.filtered_data.txt
selectedgenes 10300
outputprefix outputprefix
Output Files:
 .lsf.out
 outputprefix.expclu.gct
 stdout.txt
Execution Times:
Submitted: 13:09:33 03-05-13
Completed: 13:23:03 03-05-13
Elapsed: 00 hrs 13 mins 29 secs

step 2. GDAC_NmfConsensusClustering [id: 398896] Non-negative Matrix Factorization (NMF) Consensus Clustering, http://www.broadinstitute.org/cgi-bin/cancer/publications/pub_paper.cgi?mode=view&paper_id=89

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00379:39
expfile outputprefix.expclu.gct
k int 2
k final 8
outputprefix cnmf
Output Files:
 cnmf.normalized.gct
 cnmf.params.txt
 cnmf.consensus.all.k.plot.png
 cnmf.consensus.plot.k2.png
 cnmf.consensus.plot.k3.png
 cnmf.consensus.plot.k4.png
 cnmf.consensus.plot.k5.png
 cnmf.consensus.plot.k6.png
 cnmf.consensus.plot.k7.png
 cnmf.cophenetic.coefficient.txt
 cnmf.membership.txt
 cnmf.cophenetic.coefficient.png
 cnmf.consensus.plot.k8.png
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 13:09:33 03-05-13
Completed: 14:54:45 03-05-13
Elapsed: 01 hrs 45 mins 11 secs

step 3. GDAC_CNMFselectcluster [id: 398897] selecte best cluster

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00226:39
measure Pearson
inputexp outputprefix.expclu.gct
clumembership cnmf.membership.txt
output SKCM-BRAF_Hotspot_Mutants
inputallexp file:/xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_MethylationPreprocess/SKCM-BRAF_Hotspot_Mutants/3155607/0.GDAC_MethylationPreprocess.Finished/SKCM-BRAF_Hotspot_Mutants.meth.for_clustering.filtered_data.txt
cophenetic cnmf.cophenetic.coefficient.txt
Output Files:
 SKCM-BRAF_Hotspot_Mutants.bestclus.txt
 SKCM-BRAF_Hotspot_Mutants.cormatrix.png
 SKCM-BRAF_Hotspot_Mutants.silfig.png
 SKCM-BRAF_Hotspot_Mutants.selectmarker.txt
 SKCM-BRAF_Hotspot_Mutants.subclassmarkers.txt
 SKCM-BRAF_Hotspot_Mutants.geneheatmap.png
 SKCM-BRAF_Hotspot_Mutants.geneheatmaptopgenes.png
 .lsf.out
 stdout.txt
Execution Times:
Submitted: 13:09:33 03-05-13
Completed: 15:37:45 03-05-13
Elapsed: 02 hrs 28 mins 11 secs

step 4. GDAC_CnmfReports [id: 398898]

    urn:lsid:broadinstitute.org:cancer.genome.analysis:00414:22