Clinical Features	AGE		GENDER		HISTOLOGICAL.TYPE		RADIATIONS.RADIATION.REGIMENINDICATION		NEOADJUVANT.THERAPY	
	nMutated (%)	nWild-Type	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
BRAF	115 (57%)	86	0.44516	1	0.51698	1	4.7105e-18	4.47e-16	0.0144	1	0.57719	1
HRAS	10 (5%)	191	0.73233	1	0.72068	1	0.00015321	0.0142	1	1	1	1
NRAS	16 (8%)	185	0.81784	1	0.13216	1	9.5197e-06	0.000895	0.60408	1	1	1
POLDIP2	5 (2%)	196	0.91747	1	0.11022	1	0.6043	1	0.26728	1	1	1
EMG1	4 (2%)	197	0.68587	1	0.57432	1	1	1	1	1	1	1
EIF1AX	3 (1%)	198	0.4317	1	0.16476	1	0.036593	1	1	1	1	1
ZNF845	3 (1%)	198	0.096508	1	0.56998	1	0.55935	1	1	1	1	1
CCDC15	5 (2%)	196	0.13863	1	1	1	0.1214	1	1	1	1	1
TG	9 (4%)	192	0.35921	1	1	1	0.010858	0.999	1	1	0.12902	1
CHEK2	3 (1%)	198	0.53021	1	1	1	0.098461	1	1	1	1	1
PPM1D	5 (2%)	196	0.54456	1	1	1	0.84172	1	1	1	1	1
ZNF799	3 (1%)	198	0.94577	1	1	1	0.55935	1	1	1	1	1
SLC26A11	3 (1%)	198	0.39227	1	0.16476	1	0.72265	1	1	1	1	1
KRAS	3 (1%)	198	0.88814	1	0.56998	1	0.098461	1	1	1	1	1
ARID1B	5 (2%)	196	0.5196	1	1	1	0.21913	1	1	1	1	1
COL5A3	4 (2%)	197	0.66559	1	0.57432	1	0.28921	1	1	1	1	1
DNMT3A	4 (2%)	197	0.66477	1	1	1	0.62553	1	1	1	1	1
ARFGEF2	4 (2%)	197	0.044585	1	1	1	0.62553	1	1	1	1	1
ZFHX3	4 (2%)	197	0.70986	1	0.57432	1	0.28921	1	0.21976	1	0.058809	1