Clinical feature	Statistical test	Significant genes	Associated with	&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;	Associated with	
AGE	Spearman correlation test	N=159	older	N=158	younger	N=1
GENDER	t test	N=11	male	N=5	female	N=6
HISTOLOGICAL TYPE	ANOVA test	N=1855	 	 	 	 
RADIATIONS RADIATION REGIMENINDICATION	t test	N=38	yes	N=23	no	N=15
RADIATIONEXPOSURE	t test	N=24	yes	N=11	no	N=13
DISTANT METASTASIS	ANOVA test	N=33	 	 	 	 
EXTRATHYROIDAL EXTENSION	ANOVA test	N=33	 	 	 	 
LYMPH NODE METASTASIS	ANOVA test	N=396	 	 	 	 
COMPLETENESS OF RESECTION	ANOVA test	N=20	 	 	 	 
NUMBER OF LYMPH NODES	Spearman correlation test	N=618	higher number.of.lymph.nodes	N=13	lower number.of.lymph.nodes	N=605
NEOPLASM DISEASESTAGE	ANOVA test	N=92	 	 	 	 
MULTIFOCALITY	t test	N=0	 	 	 	 
TUMOR SIZE	Spearman correlation test	N=3	higher tumor.size	N=3	lower tumor.size	N=0
