Lissencephaly gene (LIS1) in neuronal migration and development Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations DYNC1H1 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 VLDLR 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 LRPAP1 0.027 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NUDC 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 RELN/LRP8 -0.049 0.161 -9999.0 0.0 -0.386 7.0 7.0 CaM/Ca2+ 0.019 0.004 -9999.0 0.0 -9999.0 0.0 0.0 KATNA1 0.027 0.0 -9999.0 0.0 -9999.0 0.0 0.0 GO:0030286 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ABL1 -0.064 0.135 -9999.0 0.0 -0.382 6.0 6.0 IQGAP1/CaM 0.038 0.008 -9999.0 0.0 -9999.0 0.0 0.0 DAB1 -0.003 0.021 -9999.0 0.0 -9999.0 0.0 0.0 IQGAP1 0.027 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PLA2G7 -0.06 0.199 -9999.0 0.0 -0.448 9.0 9.0 CALM1 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 DYNLT1 0.027 0.0 -9999.0 0.0 -9999.0 0.0 0.0 mol:Ca2+ -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 LRPAP1/LRP8 0.024 0.073 -9999.0 0.0 -0.425 1.0 1.0 UniProt:Q4QZ09 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CLIP1 0.027 0.0 -9999.0 0.0 -9999.0 0.0 0.0 CDK5R1 0.023 0.009 -9999.0 0.0 -9999.0 0.0 0.0 LIS1/Poliovirus Protein 3A 0.009 0.004 -9999.0 0.0 -9999.0 0.0 0.0 CDK5R2 -0.002 0.022 -9999.0 0.0 -9999.0 0.0 0.0 mol:PP1 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 RELN/VLDLR/DAB1 -0.045 0.137 -9999.0 0.0 -0.369 6.0 6.0 YWHAE 0.022 0.01 -9999.0 0.0 -9999.0 0.0 0.0 NDEL1/14-3-3 E -0.035 0.109 -9999.0 0.0 -0.508 1.0 1.0 MAP1B 0.0 0.044 -9999.0 0.0 -0.302 1.0 1.0 RAC1 0.014 0.006 -9999.0 0.0 -9999.0 0.0 0.0 p35/CDK5 -0.049 0.119 -9999.0 0.0 -0.353 5.0 5.0 RELN -0.106 0.197 -9999.0 0.0 -0.32 18.0 18.0 PAFAH/LIS1 -0.02 0.124 -9999.0 0.0 -0.365 5.0 5.0 LIS1/CLIP170 0.026 0.012 -9999.0 0.0 -9999.0 0.0 0.0 LIS1/NDEL1/Katanin 60/Dynein Light chain/Dynein heavy chain -0.024 0.097 -9999.0 0.0 -0.417 1.0 1.0 RELN/VLDLR/DAB1/LIS1/PAFAH1B2/PAFAH1B3 -0.027 0.087 -9999.0 0.0 -0.248 6.0 6.0 GO:0005869 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NDEL1 -0.047 0.108 -9999.0 0.0 -0.331 5.0 5.0 LIS1/IQGAP1 0.026 0.012 -9999.0 0.0 -9999.0 0.0 0.0 RHOA 0.013 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PAFAH1B1 0.013 0.006 -9999.0 0.0 -9999.0 0.0 0.0 PAFAH1B3 0.022 0.01 -9999.0 0.0 -9999.0 0.0 0.0 PAFAH1B2 0.013 0.085 -9999.0 0.0 -0.576 1.0 1.0 MAP1B/LIS1/Dynein heavy chain 0.026 0.013 -9999.0 0.0 -9999.0 0.0 0.0 NDEL1/Katanin 60/Dynein heavy chain -0.028 0.111 -9999.0 0.0 -0.493 1.0 1.0 LRP8 0.006 0.094 -9999.0 0.0 -0.32 3.0 3.0 NDEL1/Katanin 60 -0.036 0.109 -9999.0 0.0 -0.508 1.0 1.0 P39/CDK5 -0.058 0.124 -9999.0 0.0 -0.346 6.0 6.0 LIS1/NudC/Dynein intermediate chain/microtubule organizing center 0.025 0.012 -9999.0 0.0 -9999.0 0.0 0.0 CDK5 -0.067 0.124 -9999.0 0.0 -0.36 6.0 6.0 PPP2R5D 0.027 0.0 -9999.0 0.0 -9999.0 0.0 0.0 LIS1/CLIP170/Dynein Complex/Dynactin Complex 0.023 0.01 -9999.0 0.0 -9999.0 0.0 0.0 CSNK2A1 0.026 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RELN/VLDLR/DAB1/LIS1 -0.033 0.115 -9999.0 0.0 -0.319 5.0 5.0 RELN/VLDLR -0.038 0.153 -9999.0 0.0 -0.384 6.0 6.0 CDC42 0.013 0.006 -9999.0 0.0 -9999.0 0.0 0.0