Circadian rhythm pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations chromatin modification 0.007 0.101 -9999.0 0.0 -9999.0 0.0 0.0 CLOCK -0.054 0.202 -9999.0 0.0 -0.536 7.0 7.0 TIMELESS/CRY2 -0.0 0.098 -9999.0 0.0 -9999.0 0.0 0.0 DEC1/BMAL1 0.014 0.071 -9999.0 0.0 -0.43 1.0 1.0 ATR 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NR1D1 -0.073 0.308 -9999.0 0.0 -1.269 3.0 3.0 ARNTL 0.006 0.091 -9999.0 0.0 -0.381 2.0 2.0 TIMELESS -0.015 0.102 -9999.0 0.0 -9999.0 0.0 0.0 NPAS2 0.012 0.086 -9999.0 0.0 -0.572 1.0 1.0 CRY2 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 mol:CO 0.001 0.034 0.129 3.0 -9999.0 0.0 3.0 CHEK1 0.021 0.031 -9999.0 0.0 -9999.0 0.0 0.0 mol:HEME -0.001 0.034 -9999.0 0.0 -0.129 3.0 3.0 PER1 0.023 0.009 -9999.0 0.0 -9999.0 0.0 0.0 BMAL/CLOCK/NPAS2 -0.022 0.178 -9999.0 0.0 -0.4 8.0 8.0 BMAL1/CLOCK -0.071 0.278 -9999.0 0.0 -0.908 4.0 4.0 S phase of mitotic cell cycle 0.007 0.101 -9999.0 0.0 -9999.0 0.0 0.0 TIMELESS/CHEK1/ATR 0.007 0.102 -9999.0 0.0 -9999.0 0.0 0.0 mol:NADPH -0.001 0.034 -9999.0 0.0 -0.129 3.0 3.0 PER1/TIMELESS -0.002 0.098 -9999.0 0.0 -9999.0 0.0 0.0 PER1-2 / CRY1-2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 DEC1 -0.014 0.011 -9999.0 0.0 -9999.0 0.0 0.0