amb2 Integrin signaling Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations alphaM/beta2 Integrin/proMMP-2 -0.029 0.139 -9999.0 0.0 -0.337 7.0 7.0 alphaM/beta2 Integrin/GPIbA -0.019 0.122 -9999.0 0.0 -0.332 5.0 5.0 alphaM/beta2 Integrin/proMMP-9 -0.124 0.197 -9999.0 0.0 -0.369 17.0 17.0 PLAUR 0.005 0.059 -9999.0 0.0 -0.192 4.0 4.0 HMGB1 0.007 0.032 -9999.0 0.0 -9999.0 0.0 0.0 alphaM/beta2 Integrin/Talin -0.008 0.108 -9999.0 0.0 -0.312 4.0 4.0 AGER -0.087 0.208 -9999.0 0.0 -0.43 11.0 11.0 RAP1A 0.027 0.0 -9999.0 0.0 -9999.0 0.0 0.0 SELPLG 0.022 0.031 -9999.0 0.0 -0.192 1.0 1.0 mol:LDL -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 alphaM/beta2 Integrin/RAGE/HMGB1 -0.076 0.213 -9999.0 0.0 -0.379 14.0 14.0 mol:GTP -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 MMP9 -0.169 0.256 -9999.0 0.0 -0.429 21.0 21.0 CYR61 -0.031 0.168 -9999.0 0.0 -0.448 6.0 6.0 TLN1 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Rap1/GTP -0.042 0.122 -9999.0 0.0 -0.479 2.0 2.0 RHOA 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 P-selectin oligomer -0.035 0.182 -9999.0 0.0 -0.575 5.0 5.0 MYH2 -0.057 0.164 0.272 2.0 -0.498 3.0 5.0 MST1R 0.002 0.119 -9999.0 0.0 -0.576 2.0 2.0 leukocyte activation during inflammatory response -0.018 0.117 -9999.0 0.0 -0.38 3.0 3.0 APOB -0.012 0.089 -9999.0 0.0 -0.384 2.0 2.0 mol:GDP -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 complement component iC3b receptor activity -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 MMP2 -0.01 0.144 -9999.0 0.0 -0.576 3.0 3.0 JAM3 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 GP1BA 0.005 0.09 -9999.0 0.0 -0.384 2.0 2.0 alphaM/beta2 Integrin/CTGF -0.022 0.133 -9999.0 0.0 -0.338 6.0 6.0 alphaM/beta2 Integrin -0.064 0.129 -9999.0 0.0 -0.436 3.0 3.0 JAM3 homodimer 0.025 0.006 -9999.0 0.0 -9999.0 0.0 0.0 ICAM2 0.023 0.009 -9999.0 0.0 -9999.0 0.0 0.0 ICAM1 -0.014 0.144 -9999.0 0.0 -0.576 3.0 3.0 phagocytosis triggered by activation of immune response cell surface activating receptor -0.058 0.131 -9999.0 0.0 -0.542 2.0 2.0 cell adhesion -0.019 0.121 -9999.0 0.0 -0.33 5.0 5.0 NFKB1 -0.155 0.247 -9999.0 0.0 -0.468 16.0 16.0 THY1 0.021 0.031 -9999.0 0.0 -0.192 1.0 1.0 RhoA/GDP 0.019 0.003 -9999.0 0.0 -9999.0 0.0 0.0 Lipoprotein(a) 0.006 0.067 -9999.0 0.0 -0.369 1.0 1.0 alphaM/beta2 Integrin/LRP/tPA -0.018 0.146 -9999.0 0.0 -0.339 7.0 7.0 IL6 -0.199 0.315 -9999.0 0.0 -0.669 12.0 12.0 ITGB2 -0.003 0.061 -9999.0 0.0 -0.211 3.0 3.0 elevation of cytosolic calcium ion concentration -0.009 0.123 -9999.0 0.0 -0.325 5.0 5.0 alphaM/beta2 Integrin/JAM2/JAM3 -0.004 0.125 -9999.0 0.0 -0.346 4.0 4.0 JAM2 0.001 0.119 -9999.0 0.0 -0.576 2.0 2.0 alphaM/beta2 Integrin/ICAM1 -0.015 0.159 -9999.0 0.0 -0.382 6.0 6.0 alphaM/beta2 Integrin/uPA/Plg -0.01 0.12 -9999.0 0.0 -0.361 3.0 3.0 RhoA/GTP -0.064 0.161 -9999.0 0.0 -0.34 9.0 9.0 positive regulation of phagocytosis -0.043 0.135 -9999.0 0.0 -0.377 4.0 4.0 Ron/MSP 0.017 0.094 -9999.0 0.0 -0.425 2.0 2.0 alphaM/beta2 Integrin/uPAR/uPA -0.008 0.124 -9999.0 0.0 -0.327 5.0 5.0 alphaM/beta2 Integrin/uPAR -0.013 0.118 -9999.0 0.0 -0.331 5.0 5.0 PLAU 0.009 0.09 -9999.0 0.0 -0.576 1.0 1.0 PLAT -0.01 0.144 -9999.0 0.0 -0.576 3.0 3.0 actin filament polymerization -0.035 0.188 0.368 4.0 -0.473 3.0 7.0 MST1 0.022 0.031 -9999.0 0.0 -0.192 1.0 1.0 alphaM/beta2 Integrin/lipoprotein(a) -0.014 0.12 -9999.0 0.0 -0.384 3.0 3.0 TNF -0.215 0.332 -9999.0 0.0 -0.695 13.0 13.0 RAP1B 0.027 0.0 -9999.0 0.0 -9999.0 0.0 0.0 alphaM/beta2 Integrin/uPA -0.016 0.121 -9999.0 0.0 -0.322 5.0 5.0 fibrinolysis -0.011 0.118 -9999.0 0.0 -0.359 3.0 3.0 HCK 0.008 0.06 -9999.0 0.0 -0.192 4.0 4.0 dendritic cell antigen processing and presentation -0.058 0.131 -9999.0 0.0 -0.542 2.0 2.0 VTN -0.029 0.133 -9999.0 0.0 -0.576 2.0 2.0 alphaM/beta2 Integrin/CYR61 -0.038 0.143 -9999.0 0.0 -0.324 8.0 8.0 LPA -0.022 0.054 -9999.0 0.0 -0.192 4.0 4.0 LRP1 0.015 0.085 -9999.0 0.0 -0.576 1.0 1.0 cell migration -0.131 0.208 -9999.0 0.0 -0.382 17.0 17.0 FN1 0.004 0.066 -9999.0 0.0 -0.192 5.0 5.0 alphaM/beta2 Integrin/Thy1 -0.013 0.11 -9999.0 0.0 -0.312 4.0 4.0 MPO -0.008 0.093 -9999.0 0.0 -0.32 3.0 3.0 KNG1 -0.028 0.108 -9999.0 0.0 -0.24 8.0 8.0 RAP1/GDP 0.036 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ROCK1 -0.048 0.162 0.257 2.0 -0.608 2.0 4.0 ELA2 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 PLG -0.021 0.038 -9999.0 0.0 -0.192 2.0 2.0 CTGF -0.002 0.122 -9999.0 0.0 -0.448 3.0 3.0 alphaM/beta2 Integrin/Hck -0.013 0.122 -9999.0 0.0 -0.331 5.0 5.0 ITGAM -0.03 0.132 -9999.0 0.0 -0.361 5.0 5.0 alphaM/beta2 Integrin/P-Selectin/PSGL1 -0.028 0.154 -9999.0 0.0 -0.346 8.0 8.0 HP -0.105 0.211 -9999.0 0.0 -0.35 17.0 17.0 leukocyte adhesion -0.08 0.18 -9999.0 0.0 -0.407 7.0 7.0 SELP -0.035 0.182 -9999.0 0.0 -0.576 5.0 5.0