Replicate Samples
2017_07_24 Data Snapshot

In many instances there is more than one aliquot for a given combination of individual, platform, and data type. However, only one aliquot may be ingested into Firehose. Therefore, a set of precedence rules are applied to select the most scientifically advantageous one among them. Two filters are applied to achieve this aim: an Analyte Replicate Filter and a Sort Replicate Filter.

Analyte Replicate Filter

The following precedence rules are applied when the aliquots have differing analytes. For RNA aliquots, T analytes are dropped in preference to H and R analytes, since T is the inferior extraction protocol. If H and R are encountered, H is the chosen analyte. This is somewhat arbitrary and subject to change, since it is not clear at present whether H or R is the better protocol. If there are multiple aliquots associated with the chosen RNA analyte, the aliquot with the later plate number is chosen. For DNA aliquots, D analytes (native DNA) are preferred over G, W, or X (whole-genome amplified) analytes, unless the G, W, or X analyte sample has a higher plate number.

Sort Replicate Filter

The following precedence rules are applied when the analyte filter still produces more than one sample. The sort filter chooses the aliquot with the highest lexicographical sort value, to ensure that the barcode with the highest portion and/or plate number is selected when all other barcode fields are identical.

Table 1.  Get Full Table

Participant.Id Tumor.Type Annotation Filter.Reason Removed.Samples Chosen.Sample
TCGA-BK-A0CA UCEC CNV__snp6 Analyte Replicate Filter TCGA-BK-A0CA-10A-01D-A120-01 TCGA-BK-A0CA-10A-02D-A275-01
TCGA-BK-A0CA UCEC CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-BK-A0CA-10A-01D-A120-01 TCGA-BK-A0CA-10A-02D-A275-01
TCGA-BK-A0CA UCEC CNV__snp6 Analyte Replicate Filter TCGA-BK-A0CA-01A-21D-A120-01 TCGA-BK-A0CA-01A-21D-A275-01
TCGA-BK-A0CA UCEC CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-BK-A0CA-01A-21D-A120-01 TCGA-BK-A0CA-01A-21D-A275-01
TCGA-BK-A0CA UCEC SNV__mutect Analyte Replicate Filter TCGA-BK-A0CA-01A-21D-A122-09 TCGA-BK-A0CA-01A-21D-A272-09
TCGA-BK-A0CA UCEC mRNA__counts__FPKM Analyte Replicate Filter TCGA-BK-A0CA-01A-21R-A118-07 TCGA-BK-A0CA-01A-21R-A277-07
TCGA-BK-A0CA UCEC mRNA__geneExpNormed__FPKM Analyte Replicate Filter TCGA-BK-A0CA-01A-21R-A118-07 TCGA-BK-A0CA-01A-21R-A277-07
TCGA-BK-A0CA UCEC mRNA__geneExp__FPKM Analyte Replicate Filter TCGA-BK-A0CA-01A-21R-A118-07 TCGA-BK-A0CA-01A-21R-A277-07
TCGA-BK-A0CA UCEC methylation__HM450 Analyte Replicate Filter TCGA-BK-A0CA-01A-21D-A123-05 TCGA-BK-A0CA-01A-21D-A27B-05
TCGA-BK-A0CA UCEC miR__geneExp Analyte Replicate Filter TCGA-BK-A0CA-01A-21R-A119-13 TCGA-BK-A0CA-01A-21R-A27D-13
TCGA-BK-A0CA UCEC miR__isoformExp Analyte Replicate Filter TCGA-BK-A0CA-01A-21R-A119-13 TCGA-BK-A0CA-01A-21R-A27D-13
TCGA-BK-A0CC UCEC CNV__snp6 Analyte Replicate Filter TCGA-BK-A0CC-01A-21D-A00X-01 TCGA-BK-A0CC-01A-21D-A275-01
TCGA-BK-A0CC UCEC CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-BK-A0CC-01A-21D-A00X-01 TCGA-BK-A0CC-01A-21D-A275-01
TCGA-BK-A0CC UCEC SNV__mutect Analyte Replicate Filter TCGA-BK-A0CC-01A-21W-A027-09 TCGA-BK-A0CC-01A-21D-A272-09
TCGA-BK-A0CC UCEC mRNA__counts__FPKM Analyte Replicate Filter TCGA-BK-A0CC-01A-21R-A16W-07 TCGA-BK-A0CC-01A-21R-A277-07
TCGA-BK-A0CC UCEC mRNA__geneExpNormed__FPKM Analyte Replicate Filter TCGA-BK-A0CC-01A-21R-A16W-07 TCGA-BK-A0CC-01A-21R-A277-07
TCGA-BK-A0CC UCEC mRNA__geneExp__FPKM Analyte Replicate Filter TCGA-BK-A0CC-01A-21R-A16W-07 TCGA-BK-A0CC-01A-21R-A277-07
TCGA-BK-A0CC UCEC miR__geneExp Analyte Replicate Filter TCGA-BK-A0CC-01A-21R-A00W-13 TCGA-BK-A0CC-01A-21R-A27D-13
TCGA-BK-A0CC UCEC miR__isoformExp Analyte Replicate Filter TCGA-BK-A0CC-01A-21R-A00W-13 TCGA-BK-A0CC-01A-21R-A27D-13
TCGA-BK-A139 UCEC CNV__snp6 Analyte Replicate Filter TCGA-BK-A139-10A-01D-A120-01 TCGA-BK-A139-10A-01D-A275-01
TCGA-BK-A139 UCEC CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-BK-A139-10A-01D-A120-01 TCGA-BK-A139-10A-01D-A275-01
TCGA-BK-A139 UCEC CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-BK-A139-01A-11D-A120-01 TCGA-BK-A139-01A-11D-A275-01
TCGA-BK-A139 UCEC SNV__mutect Analyte Replicate Filter TCGA-BK-A139-01A-11D-A122-09 TCGA-BK-A139-01A-11D-A272-09
TCGA-BK-A139 UCEC mRNA__counts__FPKM Analyte Replicate Filter TCGA-BK-A139-01A-11R-A118-07 TCGA-BK-A139-01A-11R-A277-07
TCGA-BK-A139 UCEC mRNA__geneExpNormed__FPKM Analyte Replicate Filter TCGA-BK-A139-01A-11R-A118-07 TCGA-BK-A139-01A-11R-A277-07
TCGA-BK-A139 UCEC mRNA__geneExp__FPKM Analyte Replicate Filter TCGA-BK-A139-01A-11R-A118-07 TCGA-BK-A139-01A-11R-A277-07
TCGA-BK-A139 UCEC methylation__HM450 Analyte Replicate Filter TCGA-BK-A139-01A-11D-A123-05 TCGA-BK-A139-01A-11D-A27B-05
TCGA-BK-A139 UCEC miR__geneExp Analyte Replicate Filter TCGA-BK-A139-01A-11R-A119-13 TCGA-BK-A139-01A-11R-A27D-13
TCGA-BK-A139 UCEC miR__isoformExp Analyte Replicate Filter TCGA-BK-A139-01A-11R-A119-13 TCGA-BK-A139-01A-11R-A27D-13
TCGA-BK-A26L UCEC CNV__snp6 Analyte Replicate Filter TCGA-BK-A26L-10A-01D-A16C-01 TCGA-BK-A26L-10A-01D-A275-01
TCGA-BK-A26L UCEC CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-BK-A26L-10A-01D-A16C-01 TCGA-BK-A26L-10A-01D-A275-01
TCGA-BK-A26L UCEC CNV__snp6 Analyte Replicate Filter TCGA-BK-A26L-01A-11D-A16C-01 TCGA-BK-A26L-01A-11D-A275-01
TCGA-BK-A26L UCEC CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-BK-A26L-01A-11D-A16C-01 TCGA-BK-A26L-01A-11D-A275-01
TCGA-BK-A26L UCEC SNV__mutect Analyte Replicate Filter TCGA-BK-A26L-01A-11D-A16D-09 TCGA-BK-A26L-01A-11D-A272-09
TCGA-BK-A26L UCEC mRNA__counts__FPKM Analyte Replicate Filter TCGA-BK-A26L-01A-11R-A16F-07 TCGA-BK-A26L-01A-11R-A277-07
TCGA-BK-A26L UCEC mRNA__geneExpNormed__FPKM Analyte Replicate Filter TCGA-BK-A26L-01A-11R-A16F-07 TCGA-BK-A26L-01A-11R-A277-07
TCGA-BK-A26L UCEC mRNA__geneExp__FPKM Analyte Replicate Filter TCGA-BK-A26L-01A-11R-A16F-07 TCGA-BK-A26L-01A-11R-A277-07
TCGA-BK-A26L UCEC methylation__HM450 Analyte Replicate Filter TCGA-BK-A26L-01A-11D-A16G-05 TCGA-BK-A26L-01A-11D-A27B-05
TCGA-BK-A26L UCEC miR__geneExp Analyte Replicate Filter TCGA-BK-A26L-01A-11R-A16E-13 TCGA-BK-A26L-01A-11R-A27D-13
TCGA-BK-A26L UCEC miR__isoformExp Analyte Replicate Filter TCGA-BK-A26L-01A-11R-A16E-13 TCGA-BK-A26L-01A-11R-A27D-13