Replicate Samples
2017_07_28 Data Snapshot

In many instances there is more than one aliquot for a given combination of individual, platform, and data type. However, only one aliquot may be ingested into Firehose. Therefore, a set of precedence rules are applied to select the most scientifically advantageous one among them. Two filters are applied to achieve this aim: an Analyte Replicate Filter and a Sort Replicate Filter.

Analyte Replicate Filter

The following precedence rules are applied when the aliquots have differing analytes. For RNA aliquots, T analytes are dropped in preference to H and R analytes, since T is the inferior extraction protocol. If H and R are encountered, H is the chosen analyte. This is somewhat arbitrary and subject to change, since it is not clear at present whether H or R is the better protocol. If there are multiple aliquots associated with the chosen RNA analyte, the aliquot with the later plate number is chosen. For DNA aliquots, D analytes (native DNA) are preferred over G, W, or X (whole-genome amplified) analytes, unless the G, W, or X analyte sample has a higher plate number.

Sort Replicate Filter

The following precedence rules are applied when the analyte filter still produces more than one sample. The sort filter chooses the aliquot with the highest lexicographical sort value, to ensure that the barcode with the highest portion and/or plate number is selected when all other barcode fields are identical.

Table 1.  Get Full Table

Participant.Id Tumor.Type Annotation Filter.Reason Removed.Samples Chosen.Sample
TCGA-BL-A0C8 BLCA CNV__snp6 Analyte Replicate Filter TCGA-BL-A0C8-10A-01D-A10T-01 TCGA-BL-A0C8-10A-01D-A273-01
TCGA-BL-A0C8 BLCA CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-BL-A0C8-10A-01D-A10T-01 TCGA-BL-A0C8-10A-01D-A273-01
TCGA-BL-A0C8 BLCA CNV__snp6 Analyte Replicate Filter TCGA-BL-A0C8-01A-11D-A10T-01 TCGA-BL-A0C8-01A-11D-A273-01
TCGA-BL-A0C8 BLCA CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-BL-A0C8-01A-11D-A10T-01 TCGA-BL-A0C8-01A-11D-A273-01
TCGA-BL-A0C8 BLCA SNV__mutect Analyte Replicate Filter TCGA-BL-A0C8-01A-11D-A10S-08 TCGA-BL-A0C8-01A-11D-A271-08
TCGA-BL-A0C8 BLCA mRNA__counts__FPKM Analyte Replicate Filter TCGA-BL-A0C8-01A-11R-A10U-07 TCGA-BL-A0C8-01A-11R-A277-07
TCGA-BL-A0C8 BLCA mRNA__geneExpNormed__FPKM Analyte Replicate Filter TCGA-BL-A0C8-01A-11R-A10U-07 TCGA-BL-A0C8-01A-11R-A277-07
TCGA-BL-A0C8 BLCA mRNA__geneExp__FPKM Analyte Replicate Filter TCGA-BL-A0C8-01A-11R-A10U-07 TCGA-BL-A0C8-01A-11R-A277-07
TCGA-BL-A0C8 BLCA methylation__HM450 Analyte Replicate Filter TCGA-BL-A0C8-01A-11D-A10W-05 TCGA-BL-A0C8-01A-11D-A276-05
TCGA-BL-A0C8 BLCA miR__geneExp Analyte Replicate Filter TCGA-BL-A0C8-01A-11R-A10V-13 TCGA-BL-A0C8-01A-11R-A27D-13
TCGA-BL-A0C8 BLCA miR__isoformExp Analyte Replicate Filter TCGA-BL-A0C8-01A-11R-A10V-13 TCGA-BL-A0C8-01A-11R-A27D-13
TCGA-BL-A13I BLCA SNV__mutect Analyte Replicate Filter TCGA-BL-A13I-01A-11D-A13W-08 TCGA-BL-A13I-01A-11D-A271-08
TCGA-BL-A13I BLCA mRNA__counts__FPKM Analyte Replicate Filter TCGA-BL-A13I-01A-11R-A13Y-07 TCGA-BL-A13I-01A-11R-A277-07
TCGA-BL-A13I BLCA mRNA__geneExpNormed__FPKM Analyte Replicate Filter TCGA-BL-A13I-01A-11R-A13Y-07 TCGA-BL-A13I-01A-11R-A277-07
TCGA-BL-A13I BLCA mRNA__geneExp__FPKM Analyte Replicate Filter TCGA-BL-A13I-01A-11R-A13Y-07 TCGA-BL-A13I-01A-11R-A277-07
TCGA-BL-A13I BLCA methylation__HM450 Analyte Replicate Filter TCGA-BL-A13I-01A-11D-A13Z-05 TCGA-BL-A13I-01A-11D-A276-05
TCGA-BL-A13I BLCA miR__geneExp Analyte Replicate Filter TCGA-BL-A13I-01A-11R-A13X-13 TCGA-BL-A13I-01A-11R-A27D-13
TCGA-BL-A13I BLCA miR__isoformExp Analyte Replicate Filter TCGA-BL-A13I-01A-11R-A13X-13 TCGA-BL-A13I-01A-11R-A27D-13
TCGA-BL-A13J BLCA CNV__snp6 Analyte Replicate Filter TCGA-BL-A13J-10A-01D-A10T-01 TCGA-BL-A13J-10A-01D-A273-01
TCGA-BL-A13J BLCA CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-BL-A13J-10A-01D-A10T-01 TCGA-BL-A13J-10A-01D-A273-01
TCGA-BL-A13J BLCA CNV__snp6 Analyte Replicate Filter TCGA-BL-A13J-01A-11D-A10T-01 TCGA-BL-A13J-01A-11D-A273-01
TCGA-BL-A13J BLCA CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-BL-A13J-01A-11D-A10T-01 TCGA-BL-A13J-01A-11D-A273-01
TCGA-BL-A13J BLCA SNV__mutect Analyte Replicate Filter TCGA-BL-A13J-01A-11D-A10S-08 TCGA-BL-A13J-01A-11D-A271-08
TCGA-BL-A13J BLCA mRNA__counts__FPKM Analyte Replicate Filter TCGA-BL-A13J-01A-11R-A10U-07 TCGA-BL-A13J-01A-11R-A277-07
TCGA-BL-A13J BLCA mRNA__geneExpNormed__FPKM Analyte Replicate Filter TCGA-BL-A13J-01A-11R-A10U-07 TCGA-BL-A13J-01A-11R-A277-07
TCGA-BL-A13J BLCA mRNA__geneExp__FPKM Analyte Replicate Filter TCGA-BL-A13J-01A-11R-A10U-07 TCGA-BL-A13J-01A-11R-A277-07
TCGA-BL-A13J BLCA methylation__HM450 Analyte Replicate Filter TCGA-BL-A13J-01A-11D-A10W-05 TCGA-BL-A13J-01A-11D-A276-05
TCGA-BL-A13J BLCA miR__geneExp Analyte Replicate Filter TCGA-BL-A13J-01A-11R-A10V-13 TCGA-BL-A13J-01A-11R-A27D-13
TCGA-BL-A13J BLCA miR__isoformExp Analyte Replicate Filter TCGA-BL-A13J-01A-11R-A10V-13 TCGA-BL-A13J-01A-11R-A27D-13
TCGA-C4-A0F1 BLCA miR__geneExp Analyte Replicate Filter TCGA-C4-A0F1-01A-11R-A035-13 TCGA-C4-A0F1-01A-11R-A25G-13
TCGA-C4-A0F1 BLCA miR__isoformExp Analyte Replicate Filter TCGA-C4-A0F1-01A-11R-A035-13 TCGA-C4-A0F1-01A-11R-A25G-13
TCGA-C4-A0F7 BLCA miR__geneExp Analyte Replicate Filter TCGA-C4-A0F7-01A-11R-A085-13 TCGA-C4-A0F7-01A-11R-A25G-13
TCGA-C4-A0F7 BLCA miR__isoformExp Analyte Replicate Filter TCGA-C4-A0F7-01A-11R-A085-13 TCGA-C4-A0F7-01A-11R-A25G-13