Replicate Samples
2017_08_30 Data Snapshot

In many instances there is more than one aliquot for a given combination of individual, platform, and data type. However, only one aliquot may be ingested into Firehose. Therefore, a set of precedence rules are applied to select the most scientifically advantageous one among them. Two filters are applied to achieve this aim: an Analyte Replicate Filter and a Sort Replicate Filter.

Analyte Replicate Filter

The following precedence rules are applied when the aliquots have differing analytes. For RNA aliquots, T analytes are dropped in preference to H and R analytes, since T is the inferior extraction protocol. If H and R are encountered, H is the chosen analyte. This is somewhat arbitrary and subject to change, since it is not clear at present whether H or R is the better protocol. If there are multiple aliquots associated with the chosen RNA analyte, the aliquot with the later plate number is chosen. For DNA aliquots, D analytes (native DNA) are preferred over G, W, or X (whole-genome amplified) analytes, unless the G, W, or X analyte sample has a higher plate number.

Sort Replicate Filter

The following precedence rules are applied when the analyte filter still produces more than one sample. The sort filter chooses the aliquot with the highest lexicographical sort value, to ensure that the barcode with the highest portion and/or plate number is selected when all other barcode fields are identical.

Table 1.  Get Full Table

Participant.Id Tumor.Type Annotation Filter.Reason Removed.Samples Chosen.Sample
TCGA-AL-3466 KIRP CNV__snp6 Analyte Replicate Filter TCGA-AL-3466-01A-01D-1190-01 TCGA-AL-3466-01A-02D-1348-01
TCGA-AL-3466 KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-AL-3466-01A-01D-1190-01 TCGA-AL-3466-01A-02D-1348-01
TCGA-AL-3467 KIRP CNV__snp6 Analyte Replicate Filter TCGA-AL-3467-01A-01D-1190-01 TCGA-AL-3467-01A-02D-1348-01
TCGA-AL-3467 KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-AL-3467-01A-01D-1190-01 TCGA-AL-3467-01A-02D-1348-01
TCGA-AL-3468 KIRP CNV__snp6 Analyte Replicate Filter TCGA-AL-3468-01A-01D-1190-01 TCGA-AL-3468-01A-02D-1348-01
TCGA-AL-3468 KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-AL-3468-01A-01D-1190-01 TCGA-AL-3468-01A-02D-1348-01
TCGA-AL-3471 KIRP CNV__snp6 Analyte Replicate Filter TCGA-AL-3471-01A-01D-1190-01 TCGA-AL-3471-01A-02D-1348-01
TCGA-AL-3471 KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-AL-3471-01A-01D-1190-01 TCGA-AL-3471-01A-02D-1348-01
TCGA-B3-3925 KIRP CNV__snp6 Analyte Replicate Filter TCGA-B3-3925-01A-01D-1190-01 TCGA-B3-3925-01A-02D-1348-01
TCGA-B3-3925 KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-B3-3925-01A-01D-1190-01 TCGA-B3-3925-01A-02D-1348-01
TCGA-B3-3925 KIRP SNV__mutect Analyte Replicate Filter TCGA-B3-3925-01A-01D-1252-08 TCGA-B3-3925-01A-01D-1458-08
TCGA-B3-3926 KIRP CNV__snp6 Analyte Replicate Filter TCGA-B3-3926-01A-01D-1190-01 TCGA-B3-3926-01A-02D-1348-01
TCGA-B3-3926 KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-B3-3926-01A-01D-1190-01 TCGA-B3-3926-01A-02D-1348-01
TCGA-B3-4103 KIRP CNV__snp6 Analyte Replicate Filter TCGA-B3-4103-01A-01D-1190-01 TCGA-B3-4103-01A-02D-1348-01
TCGA-B3-4103 KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-B3-4103-01A-01D-1190-01 TCGA-B3-4103-01A-02D-1348-01
TCGA-B3-4103 KIRP SNV__mutect Analyte Replicate Filter TCGA-B3-4103-01A-01D-1252-08 TCGA-B3-4103-01A-01D-1458-08
TCGA-B3-4104 KIRP CNV__snp6 Analyte Replicate Filter TCGA-B3-4104-01A-01D-1190-01 TCGA-B3-4104-01A-02D-1348-01
TCGA-B3-4104 KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-B3-4104-01A-01D-1190-01 TCGA-B3-4104-01A-02D-1348-01
TCGA-B3-4104 KIRP SNV__mutect Analyte Replicate Filter TCGA-B3-4104-01A-01D-1252-08 TCGA-B3-4104-01A-01D-1458-08
TCGA-B9-4115 KIRP CNV__snp6 Analyte Replicate Filter TCGA-B9-4115-01A-01D-1190-01 TCGA-B9-4115-01A-01D-1549-01
TCGA-B9-4115 KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-B9-4115-01A-01D-1190-01 TCGA-B9-4115-01A-01D-1549-01
TCGA-B9-4115 KIRP SNV__mutect Analyte Replicate Filter TCGA-B9-4115-01A-01D-1252-08 TCGA-B9-4115-01A-01D-1553-08
TCGA-B9-4116 KIRP CNV__snp6 Analyte Replicate Filter TCGA-B9-4116-01A-01D-1190-01 TCGA-B9-4116-01A-02D-1348-01
TCGA-B9-4116 KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-B9-4116-01A-01D-1190-01 TCGA-B9-4116-01A-02D-1348-01
TCGA-B9-4117 KIRP CNV__snp6 Analyte Replicate Filter TCGA-B9-4117-01A-01D-1190-01 TCGA-B9-4117-01A-02D-1348-01
TCGA-B9-4117 KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-B9-4117-01A-01D-1190-01 TCGA-B9-4117-01A-02D-1348-01
TCGA-F9-A8NY KIRP CNV__snp6 Analyte Replicate Filter TCGA-F9-A8NY-01A-11D-A35Y-01 TCGA-F9-A8NY-01A-11D-A40C-01
TCGA-F9-A8NY KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-F9-A8NY-01A-11D-A35Y-01 TCGA-F9-A8NY-01A-11D-A40C-01
TCGA-G7-A8LB KIRP CNV__snp6 Analyte Replicate Filter TCGA-G7-A8LB-01A-11D-A35Y-01 TCGA-G7-A8LB-01A-11D-A40C-01
TCGA-G7-A8LB KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-G7-A8LB-01A-11D-A35Y-01 TCGA-G7-A8LB-01A-11D-A40C-01
TCGA-G7-A8LE KIRP CNV__snp6 Analyte Replicate Filter TCGA-G7-A8LE-01A-11D-A35Y-01 TCGA-G7-A8LE-01A-11D-A40C-01
TCGA-G7-A8LE KIRP CNV__unfiltered__snp6 Analyte Replicate Filter TCGA-G7-A8LE-01A-11D-A35Y-01 TCGA-G7-A8LE-01A-11D-A40C-01