Dear TCGA Colleagues,


The December 2011 Firehose analysis run has been uploaded and will be
available in the tcga4yeo tree pending internal mirroring by the DCC.
This analysis run was based upon version 2011_12_30 of the Firehose
stddata package, and is described in more detail on our dashboard at

    https://confluence.broadinstitute.org/display/GDAC/Status-Analysis+Runs

As our release notes indicate, mutation significance results for LUSC and
LUAD have been removed from this analysis run, due to discrepancies observed
between the set of genes identified as most significant by MutSig v1.5
(currently installed in Firehose) versus the set manually curated by the
TCGA lung AWG.  Our aim is to address this discrepancy by installing MutSig
v2 as soon as possible.

If you have any questions or comments please do not hesitate to send them
to our gdac@broadinstitute.org mailing list.


Regards,
Michael S. Noble