Dear TCGA Colleagues,

The March 2012 Firehose analysis run has been uploaded and will be available in
the protected data tree pending internal mirroring by the DCC.  This analysis
run was based upon version 2012_03_21 of the Firehose stddata package, and is
described in more detail on our site at

			http://gdac.broadinstitute.org

The highlights of this run are given below and in the dashboard release notes.
If you have any questions or comments please do not hesitate to send them to
our gdac@broadinstitute.org mailing list.


Regards,
Michael S. Noble
Broad Institute of MIT & Harvard

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    . Over 2000 new methylation samples ingested: with caveat that we do not yet
      merge multiple platforms (e.g. humanMethylation27 and 450), so methylation
      analyses will still reflect only 1 platform and thus lower counts

    . New MAFs:   BLCA (28 samples),  CESC (36), and STAD (133)

    . Initial MutSig analyses and Mutation_Assessor annotations for CESC & STAD

    . Mutation assessor module updated to reflect newer web service version and
      correct Mutation_Status column etc in outputs

    . Reflect individual RNA-Seq expression clustering reports in top-level
      aggregate report

    . A new firehose_get utility has been posted to

            http://gdac.broadinstitute.org

	  which has the potential to radically simplify retrieval of public
	  results & reports.