Dear TCGA Colleagues, Version 2012_02_17 of the Firehose stddata package has been uploaded and will be available in the tcga4yeo tree pending internal mirroring by the DCC. The highlights of this run are: 1) Methylation sample count increased by more than 1000 to 3290. 2) mRNAseq sample count increased by more than 300 to 2070. 3) Approximately 300 new BCR and clinical data samples. 4) With clinical data elements remaining stable since Sept 2011 for many tumor types, we've resumed execution of our Tier1 CDEs picker pipeline; this run includes CDEs for 14 tumor types (versus only 8 when Tier1 CDEs were last packaged in summer of 2011). Due to low sample differentials in early Feb we've performed only 1 stddata run this month. For more information please consult our dashboard at https://confluence.broadinstitute.org/display/GDAC/Dashboard-Stddata and note that to simplify data retrieval it now links directly to the DCC locations from which the corresponding archives may be downloaded. Comments and questions are welcome at gdac@broadinstitute.org. Regards, Michael S. Noble