Dear TCGA Colleagues, Version 2012_03_06 of the Firehose stddata package has been uploaded and will be available in the tcga4yeo tree pending internal mirroring by the DCC. The highlights of this run are: 1) Draft PANCANCER dataset included: 34 of 40 possible pipelines ran to completion, for an 85% success rate. At present this dataset is a simple aggregation of all tumor data, e.g. irrespective of hg18 versus hg19 alignment, but we will be advocating in followup TCGA discussions that these and other distinctions (like platform) will need to be considered more carefully in order to maximize scientific accuracy. 2) 1100 new methylation samples. 3) First samples of bladder cancer (BLCA) mutation data: 28 in all 4) To simplify access, all public archives from our stddata runs are now also hosted directly from Broad servers; no Level_1, Level_2, or PHI clinical data is included--credentialed download from the DCC remains the only way these protected data may be obtained. For more information please consult our dashboard at https://confluence.broadinstitute.org/display/GDAC/Dashboard-Stddata Comments and questions are welcome at gdac@broadinstitute.org. Regards, Michael S. Noble