Dear TCGA Colleagues,

Version 2012_12_06 of the Firehose stddata package has been released and will
be available in the protected data tree pending internal mirroring by the DCC.
Highlights of this run are given below, and in our dashboard release notes at

			http://gdac.broadinstitute.org

If you have any questions or comments please do not hesitate to send them to
our gdac@broadinstitute.org mailing list.


Regards,
Michael S. Noble
Broad Institute of MIT & Harvard

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* Sample Changes:
   BCR         +111 (7234 total)
   Clinical    +111 (5909 total)
   CN          +206 (6418 total)
   MAF         -2   (3181 total)
   Methylation +58  (6522 total)
   miRseq      -17  (5627 total)
   mRNAseq     -14  (4357 total)

  Negative values reflect recent redactions - see the Samples Summary Report at
  http://gdac.broadinstitute.org/runs/stddata__2012_12_06/samples_report/index.html

* New curated MAF from the GBM AWG - contains 291 sample (+15 new samples)

* Level 3 Clinical Parameters updated:
  1. Addition of radiation exposure (corresponds to
     patient.personlifetimeriskradiationexposureindicator in Level 2
     Data)
  2. Deletion of neoadjuvanttherapy (corresponded to
     patient.drugs.drug.regimenindication in Level 2 Data)

* Reflects the following Level 2 clinical parameters related to
  smoking to the extent available (for BLCA, CESC, HNSC, LUAD, LUSC,
  and PANCAN8 cohorts)
  1. patient.numberpackyearssmoked
  2. patient.stoppedsmokingyear
  3. patient.tobaccosmokinghistoryindicator
  4. patient.yearoftobaccosmokingonset