Dear TCGA Colleagues,

Version 2012_12_21 of the Firehose stddata package has been released and will
be available in the protected data tree pending internal mirroring by the DCC.
Highlights of this run are given below, and in our dashboard release notes at

			http://gdac.broadinstitute.org

If you have any questions or comments please do not hesitate to send them to
our gdac@broadinstitute.org mailing list.


Regards,
Michael S. Noble
Broad Institute of MIT & Harvard

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* Sample Changes:
  BCR     +73  (7307 total)
  CN      +12  (6430 total)
  LowP    +100 (601 total)
  MAF     +617 (3798 total)
  mRNAseq +323 (4680 total)

* Added New MAFs:
  - SKCM (using latest version auto-submitted by GSC to DCC)
  - KIRP (using latest version auto-submitted by GSC to DCC)
  - LGG  (using latest version auto-submitted by GSC to DCC)
  - PAAD (using latest version auto-submitted by GSC to DCC)
  - HNSC (using AWG manually-curated version): please note that, per the AWG,
		 this MAF contains contaminated samples; a new MAF is currently under
		 construction by the AWG, and should be ready for inclusion in our
		 next stddata run.

* Removed old v1.3 KIRC MAF (current version is 1.4)
  - This accounts for the 110 fewer KIRC mutation samples
  - We are aware of a new v1.5 of the KIRC MAF posted to a non-standard
	location rather than the DCC. If appropriate, it will be added to our
	next standard data run, replacing v1.4 and bringing the KIRC MAF tumor
	sample count to 499.

* Recall that firehose_get 0.3.9 was released on Dec 22nd, to boost
  performance when querying which runs are available from our site.
  You are encouraged to upgrade at your earliest convenience.