Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name_WU	start_WU	stop_WU	reference_WU	variant_WU	type_WU	gene_name_WU	transcript_name_WU	transcript_species_WU	transcript_source_WU	transcript_version_WU	strand_WU	transcript_status_WU	trv_type_WU	c_position_WU	amino_acid_change_WU	ucsc_cons_WU	domain_WU	all_domains_WU	deletion_substructures_WU	transcript_error_WU	default_gene_name_WU	gene_name_source_WU	ensembl_gene_id	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumors_var_reads	tumor_vaf	EVS_EA	EVS_AA	EVS_All
MAP3K1	0	genome.wustl.edu	37	5	56155725	56155726	+	Frame_Shift_Del	DEL	AG	AG	-			TCGA-BH-A0DV-01A-21D-A12Q-09	TCGA-BH-A0DV-11A-22D-A12Q-09	AG	AG					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	24ee6b1d-3594-4d12-91b3-8ad1b3c98f28	6d183062-662c-4ecb-9a40-01da78c6e733	5	56155725	56155726	AG	-	DEL	MAP3K1	ENST00000399503	human	ensembl	69_37n	+1	novel	frame_shift_del	c.817_818	p.R273fs	0.959:0.996	NULL	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Znf_RING,pfscan_Znf_SWIM,pfscan_Prot_kinase_cat_dom	-	no_errors	MAP3K1	HGNC	ENSG00000095015	71	0	0.00	57	9	13.64	-	-	-
NUAK2	0	genome.wustl.edu	37	1	205274440	205274440	+	Missense_Mutation	SNP	C	C	A			TCGA-BH-A0DV-01A-21D-A12Q-09	TCGA-BH-A0DV-11A-22D-A12Q-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	24ee6b1d-3594-4d12-91b3-8ad1b3c98f28	6d183062-662c-4ecb-9a40-01da78c6e733	1	205274440	205274440	C	A	SNP	NUAK2	ENST00000367157	human	ensembl	69_37n	-1	known	missense	c.710	p.G237V	1.000	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom	pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_LipoPS_kinase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom	-	no_errors	NUAK2	HGNC	ENSG00000163545	81	0	0.00	80	11	12.09	-	-	-
PIK3CA	0	genome.wustl.edu	37	3	178936091	178936091	+	Missense_Mutation	SNP	G	G	A			TCGA-BH-A0DV-01A-21D-A12Q-09	TCGA-BH-A0DV-11A-22D-A12Q-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	24ee6b1d-3594-4d12-91b3-8ad1b3c98f28	6d183062-662c-4ecb-9a40-01da78c6e733	3	178936091	178936091	G	A	SNP	PIK3CA	ENST00000263967	human	ensembl	69_37n	+1	known	missense	c.1633	p.E545K	1.000	pfam_PInositide-3_kin_accessory_dom,superfamily_ARM-type_fold,smart_PInositide-3_kin_accessory_dom	pfam_PInositide-3_kin_accessory_dom,pfam_PI3/4_kinase_cat_dom,pfam_PI3K_Ras-bd_dom,pfam_PI3K_C2_dom,pfam_PI3K_adapt-bd_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_PI3K_adapt-bd_dom,smart_PI3K_Ras-bd_dom,smart_PI3K_C2_dom,smart_PInositide-3_kin_accessory_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom	-	no_errors	PIK3CA	HGNC	ENSG00000121879	266	0	0.00	124	31	20.00	-	-	-
RSAD1	0	genome.wustl.edu	37	17	48557115	48557115	+	Silent	SNP	G	G	A			TCGA-BH-A0DV-01A-21D-A12Q-09	TCGA-BH-A0DV-11A-22D-A12Q-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	24ee6b1d-3594-4d12-91b3-8ad1b3c98f28	6d183062-662c-4ecb-9a40-01da78c6e733	17	48557115	48557115	G	A	SNP	RSAD1	ENST00000258955	human	ensembl	69_37n	+1	known	silent	c.261	p.G87	1.000	pfam_rSAM,smart_Elp3/MiaB/NifB,tigrfam_Coprogen_oxidase_HemN-rel	pfam_HemN_C_dom,pfam_rSAM,smart_Elp3/MiaB/NifB,tigrfam_Coprogen_oxidase_HemN-rel	-	no_errors	RSAD1	HGNC	ENSG00000136444	57	0	0.00	50	11	18.03	-	-	-
SHANK1	0	genome.wustl.edu	37	19	51165616	51165616	+	Missense_Mutation	SNP	C	C	A			TCGA-BH-A0DV-01A-21D-A12Q-09	TCGA-BH-A0DV-11A-22D-A12Q-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none	1	dbGAP	Illumina GAIIx	24ee6b1d-3594-4d12-91b3-8ad1b3c98f28	6d183062-662c-4ecb-9a40-01da78c6e733	19	51165616	51165616	C	A	SNP	SHANK1	ENST00000391814	human	ensembl	69_37n	-1	known	missense	c.6116	p.G2039V	1.000	NULL	pfam_Ankyrin_rpt,pfam_SAM_type1,pfam_SH3_2,pfam_SAM_2,pfam_PDZ,pfam_SH3_domain,superfamily_Ankyrin_rpt-contain_dom,superfamily_PDZ,superfamily_SH3_domain,superfamily_SAM/pointed,smart_Ankyrin_rpt,smart_SH3_domain,smart_PDZ,smart_SAM,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_PDZ,pfscan_SAM,pfscan_SH3_domain	-	no_errors	SHANK1	HGNC	ENSG00000161681	76	0	0.00	49	11	18.33	-	-	-
