Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
FCGR3B	2215	broad.mit.edu	37	1	161600959	161600959	+	Missense_Mutation	SNP	G	A	A			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr1:161600959G>A	uc009wul.3	-	0	294	c.34C>T	c.(34-36)Ccc>Tcc	p.P12S	FCGR3B_uc021pdo.1_Intron	NM_001244753	NP_001231682	O75015	FCG3B_HUMAN	Homo sapiens Fc fragment of IgG, low affinity IIIb, receptor (CD16b) (FCGR3B), transcript variant 1, mRNA.	0					immune response	anchored to membrane|extracellular region|plasma membrane	IgG binding|receptor activity			central_nervous_system(1)|endometrium(2)|kidney(3)|large_intestine(1)|lung(9)|prostate(1)|urinary_tract(1)	18	all_cancers(52;4.89e-16)|all_hematologic(112;0.0207)		BRCA - Breast invasive adenocarcinoma(70;0.00376)		Abciximab(DB00054)|Adalimumab(DB00051)|Alefacept(DB00092)|Alemtuzumab(DB00087)|Basiliximab(DB00074)|Bevacizumab(DB00112)|Cetuximab(DB00002)|Daclizumab(DB00111)|Efalizumab(DB00095)|Etanercept(DB00005)|Gemtuzumab ozogamicin(DB00056)|Ibritumomab(DB00078)|Immune globulin(DB00028)|Muromonab(DB00075)|Natalizumab(DB00108)|Palivizumab(DB00110)|Rituximab(DB00073)|Tositumomab(DB00081)|Trastuzumab(DB00072)	AGACAGGAGGGAGTAAACAGC	0.517000														22			8		0	0	1.12685e-05	0	0
DNM1	1759	broad.mit.edu	37	9	130965819	130965819	+	Missense_Mutation	SNP	G	A	A			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr9:130965819G>A	uc022bob.1	+	0	157	c.70G>A	c.(70-72)Ggc>Agc	p.G24S	CIZ1_uc004btw.3_Intron|CIZ1_uc004btv.3_Intron|DNM1_uc022bnx.1_Missense_Mutation_p.G24S|DNM1_uc022bny.1_Missense_Mutation_p.G24S|DNM1_uc022bnz.1_Missense_Mutation_p.G24S|DNM1_uc022boa.1_Missense_Mutation_p.G24S	NM_004408	NP_004399	Q05193	DYN1_HUMAN	Homo sapiens dynamin 1 (DNM1), transcript variant 1, mRNA.	24					receptor-mediated endocytosis	microtubule	GTP binding|GTPase activity			breast(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(15)|lung(6)|ovary(2)|urinary_tract(2)	32						CTCTGCCATCGGCCAGAACGC	0.682000														11			9		0	0	3.86212e-05	0	0
FCGR2C	9103	broad.mit.edu	37	1	161569429	161569429	+	RNA	SNP	C	G	G			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr1:161569429C>G	uc021pdi.1	+	6		c.907C>G				NM_201563				Homo sapiens Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) (FCGR2C), mRNA.											lung(2)	2	all_cancers(52;4.89e-16)|all_hematologic(112;0.0207)		BRCA - Breast invasive adenocarcinoma(70;0.00376)			cccacctggacgtcaaatgat	0.438000														13			6		0	0	0.000157383	0	0
IGF1R	3480	broad.mit.edu	37	15	99440126	99440126	+	Missense_Mutation	SNP	G	C	C			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr15:99440126G>C	uc002bul.3	+	3	1144	c.1094G>C	c.(1093-1095)cGa>cCa	p.R365P	IGF1R_uc010urq.2_Missense_Mutation_p.R365P|IGF1R_uc010bon.3_Missense_Mutation_p.R365P|IGF1R_uc021sxi.1_5'Flank	NM_000875	NP_000866	P08069	IGF1R_HUMAN	Homo sapiens insulin-like growth factor 1 receptor (IGF1R), mRNA.	365					anti-apoptosis|immune response|insulin receptor signaling pathway|phosphatidylinositol-mediated signaling|positive regulation of DNA replication|positive regulation of cell migration|positive regulation of cell proliferation|protein autophosphorylation|protein tetramerization	microsome	ATP binding|identical protein binding|insulin binding|insulin receptor binding|insulin receptor substrate binding|insulin-like growth factor I binding|insulin-like growth factor receptor activity|metal ion binding|phosphatidylinositol 3-kinase binding	p.I364M(1)		NS(2)|breast(1)|central_nervous_system(1)|cervix(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(8)|large_intestine(13)|lung(20)|ovary(1)|prostate(3)|upper_aerodigestive_tract(3)|urinary_tract(1)	63	all_cancers(4;4.17e-14)|all_epithelial(3;4.34e-15)|Lung NSC(78;0.00175)|all_lung(78;0.00351)|Melanoma(26;0.00505)|Medulloblastoma(229;0.163)		Epithelial(2;1.94e-12)|all cancers(5;6.83e-11)|BRCA - Breast invasive adenocarcinoma(2;2.88e-09)|OV - Ovarian serous cystadenocarcinoma(32;0.00261)		Insulin Glargine recombinant(DB00047)|Insulin Lyspro recombinant(DB00046)|Insulin recombinant(DB00030)|Insulin, porcine(DB00071)|Mecasermin(DB01277)	ATTAACATCCGACGGGGGAGT	0.443000														31			15		0	0	7.07596e-05	0	0
DHX38	9785	broad.mit.edu	37	16	72130255	72130255	+	Missense_Mutation	SNP	G	A	A			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr16:72130255G>A	uc002fcb.3	+	1	554	c.199G>A	c.(199-201)Gat>Aat	p.D67N	TXNL4B_uc010cgl.2_5'Flank|TXNL4B_uc002fca.3_5'Flank|TXNL4B_uc010vmn.2_5'Flank|TXNL4B_uc010vmo.2_5'Flank|DHX38_uc010vmp.2_Missense_Mutation_p.D67N|DHX38_uc010cgn.1_5'Flank	NM_014003	NP_054722	Q92620	PRP16_HUMAN	Homo sapiens DEAH (Asp-Glu-Ala-His) box polypeptide 38 (DHX38), mRNA.	67					mRNA 3'-end processing|mRNA export from nucleus|nuclear mRNA splicing, via spliceosome|termination of RNA polymerase II transcription	catalytic step 2 spliceosome|nucleoplasm	ATP binding|ATP-dependent helicase activity|nucleic acid binding|protein binding			endometrium(5)|kidney(1)|large_intestine(16)|lung(15)|pancreas(1)|prostate(2)|skin(5)|stomach(2)|upper_aerodigestive_tract(1)	48		Ovarian(137;0.125)				GGAGAAGGACGATGGGGAGGA	0.572000														2			16		0	0	3.45872e-05	0	0
NBPF1	55672	broad.mit.edu	37	1	16918653	16918653	+	Splice_Site	SNP	C	T	T			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr1:16918653C>T	uc009vos.1	-	6	853	c.-35_splice	c.e6+1		NBPF1_uc010oce.1_Intron	NM_017940	NP_060410	Q3BBV0	NBPF1_HUMAN	Homo sapiens neuroblastoma breakpoint family, member 1 (NBPF1), mRNA.							cytoplasm									UCEC - Uterine corpus endometrioid carcinoma (279;0.00459)|BRCA - Breast invasive adenocarcinoma(304;7.52e-06)|COAD - Colon adenocarcinoma(227;1.05e-05)|Kidney(64;0.00016)|KIRC - Kidney renal clear cell carcinoma(64;0.00258)|STAD - Stomach adenocarcinoma(196;0.00644)|READ - Rectum adenocarcinoma(331;0.0649)|Lung(427;0.179)		TCTTAACTTACTGTTGTGAAA	0.418000														51			6		0	0	1.12685e-05	0	0
TBC1D3P2	440452	broad.mit.edu	37	17	60342280	60342280	+	RNA	SNP	C	T	T	rs80012429		TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr17:60342280C>T	uc010woz.2	-	13		c.1849G>A								Homo sapiens TBC1 domain family, member 3 pseudogene 2 (TBC1D3P2), non-coding RNA.											breast(2)|kidney(1)|lung(2)	5						TTAATACATTCTCATAAGTTT	0.488000														88			17		0	0	7.07596e-05	0	0
SCAP	22937	broad.mit.edu	37	3	47462468	47462468	+	Missense_Mutation	SNP	T	C	C			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr3:47462468T>C	uc003crh.1	-	10	1552	c.1297A>G	c.(1297-1299)Atg>Gtg	p.M433V	SCAP_uc011baz.1_Missense_Mutation_p.M178V|SCAP_uc003crg.2_Missense_Mutation_p.M41V	NM_012235	NP_036367	Q12770	SCAP_HUMAN	Homo sapiens SREBF chaperone (SCAP), mRNA.	433	SSD.				cholesterol metabolic process|negative regulation of cholesterol biosynthetic process|positive regulation of low-density lipoprotein particle receptor biosynthetic process|positive regulation of transcription via sterol regulatory element binding involved in ER-nuclear sterol response pathway	ER to Golgi transport vesicle membrane|Golgi membrane|endoplasmic reticulum membrane|integral to membrane	unfolded protein binding			endometrium(4)|kidney(1)|large_intestine(4)|liver(1)|lung(11)|ovary(1)|skin(2)|upper_aerodigestive_tract(2)	26				BRCA - Breast invasive adenocarcinoma(193;0.000278)|KIRC - Kidney renal clear cell carcinoma(197;0.00592)|Kidney(197;0.00679)		AAAAACAGCATCTGAAGGAAG	0.592000											OREG0015548	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)		32			47		0	0	0.000147903	0	0
KIAA1737	85457	broad.mit.edu	37	14	77572145	77572145	+	Missense_Mutation	SNP	G	T	T			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr14:77572145G>T	uc001xtd.3	+	1	273	c.94G>T	c.(94-96)Ggg>Tgg	p.G32W	KIAA1737_uc001xtc.1_5'UTR	NM_033426	NP_219494	Q9C0C6	K1737_HUMAN	Homo sapiens KIAA1737 (KIAA1737), mRNA.	32										endometrium(2)|lung(4)|prostate(3)	9			Kidney(204;0.164)	BRCA - Breast invasive adenocarcinoma(234;0.0284)		TCGTCAGCTTGGGATGGCTGC	0.453000														88			6		2.17888e-05	0.00105119	2.17888e-05	1	0
DNAH9	1770	broad.mit.edu	37	17	11554609	11554609	+	Missense_Mutation	SNP	C	T	T			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr17:11554609C>T	uc002gne.3	+	12	2389	c.2321C>T	c.(2320-2322)gCa>gTa	p.A774V	DNAH9_uc010coo.3_Missense_Mutation_p.A68V	NM_001372	NP_001363	Q9NYC9	DYH9_HUMAN	Homo sapiens dynein, axonemal, heavy chain 9 (DNAH9), transcript variant 2, mRNA.	774	Stem (By similarity).				cell projection organization|cellular component movement|microtubule-based movement|spermatogenesis	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity			NS(2)|autonomic_ganglia(1)|breast(15)|central_nervous_system(5)|endometrium(17)|haematopoietic_and_lymphoid_tissue(6)|kidney(17)|large_intestine(49)|liver(2)|lung(123)|ovary(6)|pancreas(1)|prostate(6)|skin(21)|stomach(2)|upper_aerodigestive_tract(13)|urinary_tract(4)	290		Breast(5;0.0122)|all_epithelial(5;0.131)		Colorectal(4;6.88e-05)|COAD - Colon adenocarcinoma(4;0.000813)|READ - Rectum adenocarcinoma(10;0.157)		CGCCTCAGAGCAGCAGAGGAG	0.423000														32			12		0	0	6.40141e-05	0	0
CLCA2	9635	broad.mit.edu	37	1	86896584	86896584	+	Missense_Mutation	SNP	G	T	T			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr1:86896584G>T	uc001dlr.4	+	3	677	c.515G>T	c.(514-516)gGt>gTt	p.G172V		NM_006536	NP_006527	Q9UQC9	CLCA2_HUMAN	Homo sapiens chloride channel accessory 2 (CLCA2), mRNA.	172					cell adhesion	basal plasma membrane|cell junction|extracellular region|integral to plasma membrane	chloride channel activity			NS(2)|breast(1)|endometrium(1)|kidney(3)|large_intestine(9)|lung(18)|ovary(2)|pancreas(1)|prostate(1)|skin(3)|stomach(1)	42		Lung NSC(277;0.238)		all cancers(265;0.0233)|Epithelial(280;0.0452)		CTCCGTTGGGGTGTGTTCGAT	0.388000														52			49		2.12129e-23	1.15133e-21	0.000147903	1	0
ZFX	7543	broad.mit.edu	37	X	24229387	24229387	+	Missense_Mutation	SNP	C	G	G			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chrX:24229387C>G	uc011mjv.2	+	9	2678	c.2429C>G	c.(2428-2430)aCg>aGg	p.T810R	ZFX_uc004dbd.2_Missense_Mutation_p.T771R|ZFX_uc004dbf.3_Missense_Mutation_p.T771R|ZFX_uc004dbe.3_3'UTR|ZFX_uc022bua.1_Missense_Mutation_p.T771R|ZFX_uc010nfx.2_Missense_Mutation_p.T542R|ZFX_uc010nfz.3_Missense_Mutation_p.T427R	NM_001178086	NP_001171557	P17010	ZFX_HUMAN	Homo sapiens zinc finger protein, X-linked (ZFX), transcript variant 4, mRNA.	771					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|transcription coactivator activity|zinc ion binding			cervix(1)|endometrium(4)|kidney(3)|large_intestine(7)|liver(2)|lung(4)|ovary(2)|prostate(1)	24						TCCATTCACACGAAAGACTAT	0.453000														4			34		0	0	0.000132358	0	0
DPYSL5	56896	broad.mit.edu	37	2	27157527	27157527	+	Missense_Mutation	SNP	C	T	T			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr2:27157527C>T	uc002rhu.4	+	7	1030	c.872C>T	c.(871-873)gCg>gTg	p.A291V	DPYSL5_uc002rhv.4_Missense_Mutation_p.A291V|DPYSL5_uc021vev.1_Missense_Mutation_p.A291V	NM_020134	NP_064519	Q9BPU6	DPYL5_HUMAN	Homo sapiens dihydropyrimidinase-like 5 (DPYSL5), transcript variant 1, mRNA.	291					axon guidance|pyrimidine base catabolic process|signal transduction	cytosol	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides			breast(1)|endometrium(5)|large_intestine(2)|lung(13)|ovary(2)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	27	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)					TGGTCCCACGCGGCTGCCTAT	0.582000														66			51		0	0	0.000147903	0	0
PTEN	5728	broad.mit.edu	37	10	89717727	89717727	+	Missense_Mutation	SNP	G	T	T			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr10:89717727G>T	uc001kfb.3	+	6	1784	c.752G>T	c.(751-753)gGt>gTt	p.G251V	PTEN_uc021pvw.1_Non-coding_Transcript	NM_000314	NP_000305	P60484	PTEN_HUMAN	Homo sapiens phosphatase and tensin homolog (PTEN), mRNA.	251	C2 tensin-type.		G -> C (loss of phosphatase activity towards Ins(1,3,4,5)P4; retains ability to bind phospholipid membranes).		T cell receptor signaling pathway|activation of mitotic anaphase-promoting complex activity|apoptosis|canonical Wnt receptor signaling pathway|cell proliferation|central nervous system development|induction of apoptosis|inositol phosphate dephosphorylation|negative regulation of G1/S transition of mitotic cell cycle|negative regulation of cell migration|negative regulation of cyclin-dependent protein kinase activity involved in G1/S|negative regulation of focal adhesion assembly|negative regulation of protein kinase B signaling cascade|negative regulation of protein phosphorylation|nerve growth factor receptor signaling pathway|phosphatidylinositol dephosphorylation|phosphatidylinositol-mediated signaling|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of sequence-specific DNA binding transcription factor activity|protein stabilization|regulation of neuron projection development	PML body|cytosol|internal side of plasma membrane	PDZ domain binding|anaphase-promoting complex binding|enzyme binding|inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity|lipid binding|magnesium ion binding|phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity|phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity|phosphatidylinositol-3-phosphatase activity|protein serine/threonine phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity	p.0?(37)|p.C250fs*2(6)|p.R55fs*1(5)|p.G251C(4)|p.G251D(4)|p.N212fs*1(2)|p.G251V(2)|p.Y27fs*1(2)|p.G251fs*6(2)|p.G165_*404del(1)|p.?(1)|p.G165_K342del(1)|p.C250*(1)|p.C250fs*10(1)		NS(28)|autonomic_ganglia(2)|biliary_tract(6)|bone(5)|breast(92)|central_nervous_system(676)|cervix(26)|endometrium(1068)|eye(8)|haematopoietic_and_lymphoid_tissue(137)|kidney(24)|large_intestine(98)|liver(20)|lung(91)|meninges(2)|oesophagus(2)|ovary(82)|pancreas(6)|prostate(129)|salivary_gland(5)|skin(127)|soft_tissue(19)|stomach(30)|testis(1)|thyroid(29)|upper_aerodigestive_tract(29)|urinary_tract(12)|vulva(17)	2771		all_cancers(4;3.61e-31)|all_epithelial(4;3.96e-23)|Prostate(4;8.12e-23)|Breast(4;0.000111)|Melanoma(5;0.00146)|all_hematologic(4;0.00227)|Colorectal(252;0.00494)|all_neural(4;0.00513)|Acute lymphoblastic leukemia(4;0.0116)|Glioma(4;0.0274)|all_lung(38;0.132)	KIRC - Kidney renal clear cell carcinoma(1;0.214)	UCEC - Uterine corpus endometrioid carcinoma (6;0.000228)|all cancers(1;4.16e-84)|GBM - Glioblastoma multiforme(1;7.77e-49)|Epithelial(1;7.67e-41)|OV - Ovarian serous cystadenocarcinoma(1;6.22e-15)|BRCA - Breast invasive adenocarcinoma(1;1.1e-06)|Lung(2;3.18e-06)|Colorectal(12;4.88e-06)|LUSC - Lung squamous cell carcinoma(2;4.97e-06)|COAD - Colon adenocarcinoma(12;1.13e-05)|Kidney(1;0.000288)|KIRC - Kidney renal clear cell carcinoma(1;0.00037)|STAD - Stomach adenocarcinoma(243;0.218)		CCTGTGTGTGGTGATATCAAA	0.398000		31	"""D, Mis, N, F, S"""		"""glioma,  prostate, endometrial"""	"""harmartoma, glioma,  prostate, endometrial"""			Proteus syndrome;Juvenile Polyposis;Hereditary Mixed Polyposis Syndrome type 1;Cowden syndrome;Bannayan-Riley-Ruvalcaba syndrome	HNSCC(9;0.0022)|TCGA GBM(2;<1E-08)|TSP Lung(26;0.18)				1			17		1.01871e-10	5.14331e-09	0.000132079	1	0
NBPF10	100132406	broad.mit.edu	37	1	144815968	144815968	+	Missense_Mutation	SNP	G	A	A			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr1:144815968G>A	uc009wig.1	+	10	1527	c.1333G>A	c.(1333-1335)Gtt>Att	p.V445I	NBPF10_uc010oxo.1_Missense_Mutation_p.V447I|NBPF10_uc010oxn.1_Intron|NBPF10_uc021oth.1_Intron|NBPF10_uc021otj.1_Intron|NBPF10_uc021oto.1_Intron|NBPF10_uc021otr.1_Intron|NBPF10_uc021ots.1_Intron|NBPF10_uc021otv.1_Intron|NBPF10_uc001ekk.1_Intron|NBPF10_uc010oyd.1_Intron|NBPF10_uc010oye.2_Intron|NBPF10_uc001eli.3_Non-coding_Transcript|NBPF10_uc009wii.1_Missense_Mutation_p.V176I|PDE4DIP_uc001elk.2_Intron|PDE4DIP_uc001ell.2_Intron|PDE4DIP_uc001elm.4_Intron|PDE4DIP_uc001eln.4_Intron|PDE4DIP_uc001elo.3_Intron|NBPF10_uc021ouf.1_Missense_Mutation_p.V107I	NM_001037675	NP_001032764	A6NDV3	A6NDV3_HUMAN	Homo sapiens neuroblastoma breakpoint family, member 9 (NBPF9), mRNA.	447								p.V189I(1)		NS(3)|breast(1)|central_nervous_system(3)|endometrium(12)|kidney(23)|lung(15)|ovary(1)|prostate(7)|skin(6)|urinary_tract(2)	73	all_hematologic(923;0.032)			Colorectal(1306;1.36e-07)|KIRC - Kidney renal clear cell carcinoma(1967;0.00258)		AGATGTTCAAGTTGAGGTGGC	0.423000														68			16		0	0	0.000229342	0	0
FMNL1	752	broad.mit.edu	37	17	43309817	43309817	+	Silent	SNP	G	A	A			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr17:43309817G>A	uc002iin.3	+	2	497	c.297G>A	c.(295-297)aaG>aaA	p.K99K	FMNL1_uc002iio.3_Splice_Site_p.K54_splice|FMNL1_uc002iip.1_5'Flank	NM_005892	NP_005883	O95466	FMNL_HUMAN	Homo sapiens formin-like 1 (FMNL1), mRNA.	99	GBD/FH3.				actin cytoskeleton organization		Rho GTPase binding|actin binding			biliary_tract(1)|breast(1)|central_nervous_system(1)|endometrium(4)|kidney(2)|large_intestine(8)|lung(12)|pancreas(1)|skin(1)|urinary_tract(2)	33						TCAGCCGAAAGGTAGCAGCTG	0.542000														16			10		0	0	6.40141e-05	0	0
MED22	6837	broad.mit.edu	37	9	136210997	136210997	+	Silent	SNP	C	T	T			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr9:136210997C>T	uc004cdc.3	-	3	630	c.396G>A	c.(394-396)gaG>gaA	p.E132E	MED22_uc004cdd.3_Silent_p.E132E	NM_133640	NP_598395	Q15528	MED22_HUMAN	Homo sapiens mediator complex subunit 22 (MED22), transcript variant b, mRNA.	132					regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	cytoplasm|mediator complex|soluble fraction	protein binding			endometrium(1)|large_intestine(1)|ovary(1)|urinary_tract(1)	4				OV - Ovarian serous cystadenocarcinoma(145;1.14e-06)|Epithelial(140;8.2e-06)|all cancers(34;6.94e-05)		AGTAATACTCCTCCTCCAGCT	0.607000														24			24		0	0	9.22233e-05	0	0
MLL3	58508	broad.mit.edu	37	7	151891141	151891141	+	Nonsense_Mutation	SNP	A	T	T			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr7:151891141A>T	uc003wla.3	-	30	4832	c.4613T>A	c.(4612-4614)tTg>tAg	p.L1538*	MLL3_uc003wkz.3_Nonsense_Mutation_p.L599*	NM_170606	NP_733751	Q8NEZ4	MLL3_HUMAN	Homo sapiens myeloid/lymphoid or mixed-lineage leukemia 3 (MLL3), mRNA.	1538					intracellular signal transduction|regulation of transcription, DNA-dependent|transcription, DNA-dependent		DNA binding|protein binding|zinc ion binding			NS(6)|biliary_tract(9)|breast(24)|central_nervous_system(18)|cervix(6)|endometrium(31)|haematopoietic_and_lymphoid_tissue(1)|kidney(26)|large_intestine(52)|liver(1)|lung(102)|ovary(10)|pancreas(17)|prostate(15)|skin(20)|soft_tissue(1)|stomach(3)|upper_aerodigestive_tract(8)|urinary_tract(15)	365	all_neural(206;0.187)	all_hematologic(28;0.0592)|Prostate(32;0.0906)	OV - Ovarian serous cystadenocarcinoma(82;0.00715)	UCEC - Uterine corpus endometrioid carcinoma (81;0.0597)|BRCA - Breast invasive adenocarcinoma(188;0.0462)		AGGCTGTGGCAATGGAGTTGG	0.393000			N		medulloblastoma									0			22		0	0	7.16444e-05	0	0
SLC6A13	6540	broad.mit.edu	37	12	330229	330229	+	Missense_Mutation	SNP	C	T	T	rs141229734		TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr12:330229C>T	uc001qic.2	-	14	1784	c.1694G>A	c.(1693-1695)cGt>cAt	p.R565H	SLC6A13_uc009zdj.2_Missense_Mutation_p.R555H|SLC6A13_uc010sdl.2_Missense_Mutation_p.R473H	NM_016615	NP_057699	Q9NSD5	S6A13_HUMAN	Homo sapiens solute carrier family 6 (neurotransmitter transporter, GABA), member 13 (SLC6A13), transcript variant 1, mRNA.	565					neurotransmitter secretion	integral to plasma membrane	gamma-aminobutyric acid:sodium symporter activity|neurotransmitter:sodium symporter activity	p.R565C(1)		NS(1)|autonomic_ganglia(1)|central_nervous_system(1)|endometrium(4)|kidney(1)|large_intestine(7)|lung(11)|prostate(1)|urinary_tract(1)	28	all_cancers(10;0.0416)|all_epithelial(11;0.0537)|all_lung(10;0.0989)|Lung NSC(10;0.139)|Ovarian(42;0.142)		OV - Ovarian serous cystadenocarcinoma(31;0.00153)|BRCA - Breast invasive adenocarcinoma(9;0.239)			CATGAGCTGACGGATTCTCTG	0.652000														17			8		0	0	2.17888e-05	0	0
TBC1D3P2	440452	broad.mit.edu	37	17	60342294	60342294	+	RNA	SNP	A	C	C	rs76100965		TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr17:60342294A>C	uc010woz.2	-	13		c.1835T>G								Homo sapiens TBC1 domain family, member 3 pseudogene 2 (TBC1D3P2), non-coding RNA.											breast(2)|kidney(1)|lung(2)	5						TAAGTTTAACAAAAAATAAAA	0.483000														86			17		0	0	9.7654e-05	0	0
NBPF10	100132406	broad.mit.edu	37	1	144815953	144815953	+	Missense_Mutation	SNP	A	G	G			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr1:144815953A>G	uc009wig.1	+	10	1512	c.1318A>G	c.(1318-1320)Aat>Gat	p.N440D	NBPF10_uc010oxo.1_Missense_Mutation_p.N442D|NBPF10_uc010oxn.1_Intron|NBPF10_uc021oth.1_Intron|NBPF10_uc021otj.1_Intron|NBPF10_uc021oto.1_Intron|NBPF10_uc021otr.1_Intron|NBPF10_uc021ots.1_Intron|NBPF10_uc021otv.1_Intron|NBPF10_uc001ekk.1_Intron|NBPF10_uc010oyd.1_Intron|NBPF10_uc010oye.2_Intron|NBPF10_uc001eli.3_Non-coding_Transcript|NBPF10_uc009wii.1_Missense_Mutation_p.N171D|PDE4DIP_uc001elk.2_Intron|PDE4DIP_uc001ell.2_Intron|PDE4DIP_uc001elm.4_Intron|PDE4DIP_uc001eln.4_Intron|PDE4DIP_uc001elo.3_Intron|NBPF10_uc021ouf.1_Missense_Mutation_p.N102D	NM_001037675	NP_001032764	A6NDV3	A6NDV3_HUMAN	Homo sapiens neuroblastoma breakpoint family, member 9 (NBPF9), mRNA.	442								p.N184D(2)		NS(3)|breast(1)|central_nervous_system(3)|endometrium(12)|kidney(23)|lung(15)|ovary(1)|prostate(7)|skin(6)|urinary_tract(2)	73	all_hematologic(923;0.032)			Colorectal(1306;1.36e-07)|KIRC - Kidney renal clear cell carcinoma(1967;0.00258)		CAACGATGACAATGAAGATGT	0.423000														72			15		0	0	2.31682e-05	0	0
CCDC160	347475	broad.mit.edu	37	X	133379086	133379086	+	Missense_Mutation	SNP	A	G	G			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chrX:133379086A>G	uc011mvj.2	+	1	577	c.256A>G	c.(256-258)Att>Gtt	p.I86V		NM_001101357	NP_001094827	A6NGH7	CC160_HUMAN	Homo sapiens coiled-coil domain containing 160 (CCDC160), mRNA.	86										endometrium(1)|kidney(2)|large_intestine(10)|lung(2)|prostate(1)|skin(1)	17						CAAGAGAAACATTTCAAAGAA	0.294000														1			7		0	0	8.12818e-05	0	0
SOHLH1	402381	broad.mit.edu	37	9	138590185	138590185	+	Missense_Mutation	SNP	T	A	A			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr9:138590185T>A	uc010nbe.3	-	2	396	c.335A>T	c.(334-336)gAg>gTg	p.E112V	SOHLH1_uc004cgl.3_Missense_Mutation_p.E112V	NM_001101677	NP_001095147	Q5JUK2	SOLH1_HUMAN	Homo sapiens spermatogenesis and oogenesis specific basic helix-loop-helix 1 (SOHLH1), transcript variant 1, mRNA.	112					cell differentiation|multicellular organismal development|oogenesis|regulation of transcription, DNA-dependent|spermatogenesis|transcription, DNA-dependent	cytoplasm|nucleus	DNA binding			breast(1)|central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(3)|large_intestine(1)|lung(5)|prostate(1)	12		Myeloproliferative disorder(178;0.0511)		OV - Ovarian serous cystadenocarcinoma(145;1.66e-07)|Epithelial(140;1.11e-06)|all cancers(34;6.45e-05)		AGCGTGCTGCTCCTGACTGGG	0.642000														32			27		0	0	0.000227799	0	0
SORCS3	22986	broad.mit.edu	37	10	107006985	107006985	+	Missense_Mutation	SNP	C	A	A			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr10:107006985C>A	uc001kyi.1	+	21	3228	c.3001C>A	c.(3001-3003)Cag>Aag	p.Q1001K	SORCS3_uc010qqz.1_Non-coding_Transcript	NM_014978	NP_055793	Q9UPU3	SORC3_HUMAN	Homo sapiens sortilin-related VPS10 domain containing receptor 3 (SORCS3), mRNA.	1001						integral to membrane	neuropeptide receptor activity			autonomic_ganglia(1)|breast(3)|central_nervous_system(1)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(6)|large_intestine(19)|lung(63)|ovary(6)|pancreas(1)|prostate(6)|skin(8)|stomach(3)|upper_aerodigestive_tract(3)|urinary_tract(2)	131		Colorectal(252;0.134)|Breast(234;0.142)|Lung NSC(174;0.191)		Epithelial(162;1.58e-07)|all cancers(201;1.02e-05)|BRCA - Breast invasive adenocarcinoma(275;0.0628)		AGAATATTTCCAGTCCCAGCT	0.468000														0			5		3.59834e-05	0.00169826	3.59834e-05	1	0
TRIM38	10475	broad.mit.edu	37	6	25983718	25983718	+	Missense_Mutation	SNP	A	G	G	rs139300929		TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr6:25983718A>G	uc003nfm.3	+	7	1636	c.1201A>G	c.(1201-1203)Act>Gct	p.T401A	TRIM38_uc010jqd.3_Missense_Mutation_p.T37A	NM_006355	NP_006346	O00635	TRI38_HUMAN	Homo sapiens tripartite motif containing 38 (TRIM38), mRNA.	401	B30.2/SPRY.				positive regulation of I-kappaB kinase/NF-kappaB cascade	intracellular	signal transducer activity|zinc ion binding			breast(3)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(5)|lung(8)|upper_aerodigestive_tract(2)	23						TTCTCCCCCAACTTCCCTTCA	0.507000														57			22		0	0	9.22233e-05	0	0
TAS2R31	259290	broad.mit.edu	37	12	11183406	11183406	+	Missense_Mutation	SNP	C	T	T			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr12:11183406C>T	uc001qzo.1	-	0	601	c.529G>A	c.(529-531)Gcg>Acg	p.A177T	PRH1_uc001qzb.4_Intron|TAS2R14_uc021qve.1_Intron|PRH1_uc021qvg.1_Intron|PRB4_uc001qzf.1_Intron|TAS2R14_uc001qzj.3_Intron	NM_176885	NP_795366	P59538	T2R31_HUMAN	Homo sapiens taste receptor, type 2, member 31 (TAS2R31), mRNA.	177					sensory perception of taste	integral to membrane	G-protein coupled receptor activity			kidney(1)|lung(6)	7						GTTACAGTCGCATCTGAAAGG	0.393000														58			6		0	0	2.17888e-05	0	0
TBC1D3P2	440452	broad.mit.edu	37	17	60342311	60342311	+	RNA	SNP	G	T	T			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr17:60342311G>T	uc010woz.2	-	13		c.1818C>A								Homo sapiens TBC1 domain family, member 3 pseudogene 2 (TBC1D3P2), non-coding RNA.											breast(2)|kidney(1)|lung(2)	5						AAAACGAGGAGGCGAAGCTTG	0.458000														87			17		3.99206e-14	2.06351e-12	9.7654e-05	1	0
GSG1L	146395	broad.mit.edu	37	16	27974490	27974490	+	Silent	SNP	C	T	T			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr16:27974490C>T	uc002doz.2	-	1	469	c.384G>A	c.(382-384)ccG>ccA	p.P128P	GSG1L_uc010bya.1_Silent_p.P128P	NM_001109763	NP_653276	Q6UXU4	GSG1L_HUMAN	Homo sapiens GSG1-like (GSG1L), transcript variant 1, mRNA.	128						integral to membrane		p.P128P(1)|p.G128W(1)		endometrium(2)|large_intestine(2)|lung(8)|ovary(1)|prostate(4)	17						TCTCCGATGCCGGGGCCAGGT	0.542000														17			8		0	0	2.17888e-05	0	0
NRK	203447	broad.mit.edu	37	X	105178259	105178259	+	Missense_Mutation	SNP	G	C	C			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chrX:105178259G>C	uc004emd.3	+	19	3625	c.3322G>C	c.(3322-3324)Ggt>Cgt	p.G1108R	NRK_uc010npc.1_Missense_Mutation_p.G776R	NM_198465	NP_940867	Q7Z2Y5	NRK_HUMAN	Homo sapiens Nik related kinase (NRK), mRNA.	1108							ATP binding|protein serine/threonine kinase activity|small GTPase regulator activity			breast(8)|central_nervous_system(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(14)|lung(36)|ovary(3)|prostate(1)|skin(2)	76						GGAGCCAGGTGGTGGAAATGA	0.418000										HNSCC(51;0.14)				23			3		0	0	1.23904e-05	0	0
ST6GALNAC3	256435	broad.mit.edu	37	1	76877888	76877888	+	Missense_Mutation	SNP	C	G	G			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr1:76877888C>G	uc001dhh.2	+	2	572	c.409C>G	c.(409-411)Cta>Gta	p.L137V	ST6GALNAC3_uc001dhg.4_Missense_Mutation_p.L137V|ST6GALNAC3_uc010orh.1_Missense_Mutation_p.L72V	NM_152996	NP_694541	Q8NDV1	SIA7C_HUMAN	Homo sapiens ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1, 3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 (ST6GALNAC3), transcript variant 1, mRNA.	137					protein glycosylation	integral to Golgi membrane	sialyltransferase activity			breast(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(5)|lung(20)|ovary(3)|prostate(1)|skin(2)	36						TCCTCTTTTGCTAAAAAACCC	0.418000														16			17		0	0	5.01169e-05	0	0
FRG1	2483	broad.mit.edu	37	4	190876268	190876268	+	Missense_Mutation	SNP	A	G	G	rs145193566	by1000genomes	TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr4:190876268A>G	uc003izs.3	+	4	585	c.394A>G	c.(394-396)Att>Gtt	p.I132V		NM_004477	NP_004468	Q14331	FRG1_HUMAN	Homo sapiens FSHD region gene 1 (FRG1), mRNA.	132					rRNA processing	Cajal body|catalytic step 2 spliceosome|nuclear speck|nucleolus		p.I132T(1)		NS(2)|breast(1)|central_nervous_system(1)|endometrium(2)|lung(11)|ovary(1)|pancreas(1)|prostate(5)|skin(7)|urinary_tract(1)	32		all_cancers(14;1.44e-58)|all_epithelial(14;6.32e-41)|all_lung(41;8.13e-17)|Lung NSC(41;2.13e-16)|Breast(6;2.54e-06)|Melanoma(20;0.000263)|Hepatocellular(41;0.00213)|Renal(120;0.0183)|all_hematologic(60;0.0358)|Prostate(90;0.0421)|all_neural(102;0.147)		all cancers(3;1.73e-30)|Epithelial(3;5.85e-30)|OV - Ovarian serous cystadenocarcinoma(60;5.56e-15)|BRCA - Breast invasive adenocarcinoma(30;9.14e-06)|Lung(3;3.54e-05)|STAD - Stomach adenocarcinoma(60;8.83e-05)|LUSC - Lung squamous cell carcinoma(40;0.000198)|GBM - Glioblastoma multiforme(59;0.00892)|READ - Rectum adenocarcinoma(43;0.161)		TTCAGATGCAATTGGACCAAG	0.358000														96			4		0	0	1.23904e-05	0	0
NBPF10	100132406	broad.mit.edu	37	1	144828683	144828683	+	Missense_Mutation	SNP	C	G	G			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr1:144828683C>G	uc009wig.1	+	21	2916	c.2722C>G	c.(2722-2724)Cag>Gag	p.Q908E	NBPF10_uc010oxo.1_Missense_Mutation_p.Q835E|NBPF10_uc010oxn.1_Missense_Mutation_p.Q808E|NBPF10_uc021oth.1_Missense_Mutation_p.Q570E|NBPF10_uc021otj.1_Missense_Mutation_p.Q937E|NBPF10_uc021oto.1_Missense_Mutation_p.Q725E|NBPF10_uc021otr.1_Missense_Mutation_p.Q237E|NBPF10_uc021ots.1_Intron|NBPF10_uc001ekk.1_Missense_Mutation_p.Q481E|NBPF10_uc010oyd.1_Missense_Mutation_p.Q237E|NBPF10_uc010oye.2_Intron|NBPF10_uc001eli.3_Non-coding_Transcript|PDE4DIP_uc001elk.2_Intron|PDE4DIP_uc001ell.2_Intron|PDE4DIP_uc001elm.4_Intron|PDE4DIP_uc001eln.4_Intron|PDE4DIP_uc001elo.3_Intron	NM_001037675	NP_001032764	A6NDV3	A6NDV3_HUMAN	Homo sapiens neuroblastoma breakpoint family, member 9 (NBPF9), mRNA.	910								p.Q577E(1)		NS(3)|breast(1)|central_nervous_system(3)|endometrium(12)|kidney(23)|lung(15)|ovary(1)|prostate(7)|skin(6)|urinary_tract(2)	73	all_hematologic(923;0.032)			Colorectal(1306;1.36e-07)|KIRC - Kidney renal clear cell carcinoma(1967;0.00258)		ATTTGAGGAACAGCACATCAG	0.438000														142			26		0	0	0.000227799	0	0
MAP3K6	9064	broad.mit.edu	37	1	27688678	27688678	+	Missense_Mutation	SNP	T	A	A			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr1:27688678T>A	uc001bny.1	-	8	1568	c.1319A>T	c.(1318-1320)gAt>gTt	p.D440V	MAP3K6_uc009vsw.1_Missense_Mutation_p.D432V|MAP3K6_uc001bnz.1_5'Flank	NM_004672	NP_004663	O95382	M3K6_HUMAN	Homo sapiens mitogen-activated protein kinase kinase kinase 6 (MAP3K6), mRNA.	440				MQYYWD -> ALWVPV (in Ref. 3; AAI29952).|MQYYWD -> HTWVPV (in Ref. 3; AAI29951).	activation of JUN kinase activity		ATP binding|MAP kinase kinase kinase activity|magnesium ion binding			breast(4)|central_nervous_system(2)|lung(3)|ovary(1)	10		all_lung(284;1.6e-05)|Lung NSC(340;2.92e-05)|Colorectal(325;3.46e-05)|Renal(390;0.0007)|Breast(348;0.0021)|Ovarian(437;0.0175)|Myeloproliferative disorder(586;0.0255)|all_neural(195;0.0381)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0416)|OV - Ovarian serous cystadenocarcinoma(117;1.69e-27)|Colorectal(126;1.24e-08)|COAD - Colon adenocarcinoma(152;1.7e-06)|BRCA - Breast invasive adenocarcinoma(304;0.00132)|KIRC - Kidney renal clear cell carcinoma(1967;0.00163)|STAD - Stomach adenocarcinoma(196;0.00303)|READ - Rectum adenocarcinoma(331;0.0419)		GAAACCCACATCCCAGTAATA	0.597000														8			13		0	0	0.000151284	0	0
PCNX	22990	broad.mit.edu	37	14	71540341	71540341	+	Silent	SNP	T	C	C			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr14:71540341T>C	uc001xmo.2	+	26	5378	c.4932T>C	c.(4930-4932)ccT>ccC	p.P1644P	PCNX_uc010are.1_Silent_p.P1533P|PCNX_uc010arf.1_Silent_p.P432P	NM_014982	NP_055797	Q96RV3	PCX1_HUMAN	Homo sapiens pecanex homolog (Drosophila) (PCNX), mRNA.	1644						integral to membrane				NS(2)|biliary_tract(1)|breast(3)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(14)|liver(2)|lung(40)|ovary(1)|prostate(7)|skin(2)|urinary_tract(1)	87			KIRC - Kidney renal clear cell carcinoma(12;0.206)	all cancers(60;0.00835)|BRCA - Breast invasive adenocarcinoma(234;0.00951)|OV - Ovarian serous cystadenocarcinoma(108;0.0417)		GTTGTGAACCTGGCCATATTC	0.453000														39			24		0	0	9.22233e-05	0	0
SNW1	22938	broad.mit.edu	37	14	78187103	78187103	+	Missense_Mutation	SNP	C	A	A			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr14:78187103C>A	uc010tvn.1	-	11	1226	c.1199G>T	c.(1198-1200)cGg>cTg	p.R400L	SNW1_uc001xuf.3_Missense_Mutation_p.R400L|SNW1_uc010tvm.2_Missense_Mutation_p.R325L			Q13573	SNW1_HUMAN	Homo sapiens SNW domain containing 1 (SNW1), mRNA.	400					negative regulation of transcription, DNA-dependent|nuclear mRNA splicing, via spliceosome|regulation of transcription from RNA polymerase II promoter	catalytic step 2 spliceosome|nucleoplasm	Notch binding			NS(1)|endometrium(3)|kidney(3)|large_intestine(6)|lung(6)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	24			Kidney(204;0.164)	BRCA - Breast invasive adenocarcinoma(234;0.0291)		ATTGGAAGTCCGAGGATTAGG	0.388000														53			36		2.75727e-19	1.46001e-17	0.000159656	1	0
NCOA3	8202	broad.mit.edu	37	20	46262905	46262905	+	Missense_Mutation	SNP	C	G	G			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr20:46262905C>G	uc002xtk.3	+	9	1339	c.1078C>G	c.(1078-1080)Cga>Gga	p.R360G	NCOA3_uc002xtl.3_Missense_Mutation_p.R360G|NCOA3_uc002xtn.3_Missense_Mutation_p.R360G|NCOA3_uc010ght.2_Missense_Mutation_p.R370G|NCOA3_uc002xtm.3_Missense_Mutation_p.R360G|NCOA3_uc010zyc.2_Missense_Mutation_p.R155G	NM_181659	NP_858045	Q9Y6Q9	NCOA3_HUMAN	Homo sapiens nuclear receptor coactivator 3 (NCOA3), transcript variant 1, mRNA.	360					androgen receptor signaling pathway|cellular lipid metabolic process|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	nucleoplasm	androgen receptor binding|histone acetyltransferase activity|ligand-dependent nuclear receptor binding|protein N-terminus binding|signal transducer activity|thyroid hormone receptor binding	p.D359V(1)		breast(3)|endometrium(3)|kidney(4)|large_intestine(12)|lung(19)|ovary(4)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	52						AACAAATGATCGACATGGCTT	0.388000														50			31		0	0	0.000159656	0	0
CCDC28B	79140	broad.mit.edu	37	1	32670247	32670248	+	Frame_Shift_Del	DEL	TG	-	-			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr1:32670247_32670248delTG	uc021okt.1	+	4	706_707	c.574_575delTG	c.(574-576)tgtfs	p.C192fs	CCDC28B_uc001bul.1_Intron|IQCC_uc001bum.2_5'Flank|IQCC_uc009vua.2_5'Flank|IQCC_uc010ogz.1_5'Flank	NM_024296	NP_077272	Q9BUN5	CC28B_HUMAN	Homo sapiens coiled-coil domain containing 28B (CCDC28B), mRNA.	0								p.A192V(1)		large_intestine(4)|lung(3)|ovary(1)|upper_aerodigestive_tract(2)	10		Myeloproliferative disorder(586;0.0255)|all_neural(195;0.0837)|Ovarian(437;0.101)|Breast(348;0.174)				AACCCGTCTATGTGTGTGTGTT	0.500													---	166	---	---	7	---					
FLG	2312	broad.mit.edu	37	1	152276467	152276468	+	In_Frame_Ins	INS	-	GGA	GGA			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr1:152276467_152276468insGGA	uc001ezu.1	-	2	10930_10931	c.10894_10895insTCC	c.(10894-10896)cag>cTCCag	p.3631_3632insL		NM_002016	NP_002007	P20930	FILA_HUMAN	Homo sapiens filaggrin (FLG), mRNA.	3631	Ser-rich.				keratinocyte differentiation	cytoplasmic membrane-bounded vesicle|intermediate filament	calcium ion binding|structural molecule activity			autonomic_ganglia(1)|breast(13)|central_nervous_system(5)|cervix(2)|endometrium(38)|haematopoietic_and_lymphoid_tissue(1)|kidney(16)|large_intestine(57)|lung(211)|ovary(13)|pancreas(1)|prostate(15)|skin(24)|stomach(5)|upper_aerodigestive_tract(10)|urinary_tract(12)	424	Hepatocellular(266;0.0877)|Melanoma(130;0.116)|all_hematologic(923;0.127)		LUSC - Lung squamous cell carcinoma(543;0.206)			GTCTGCTGACTGCTGGTGGTGG	0.554									Ichthyosis				---	643	---	---	8	---					
ITPKB	3707	broad.mit.edu	37	1	226924876	226924884	+	In_Frame_Del	DEL	CTGCCGCTG	-	-	rs11278152		TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr1:226924876_226924884delCTGCCGCTG	uc010pvo.2	-	1	616_624	c.276_284delCAGCGGCAG	c.(274-285)agcagcggcagt>agt	p.92_95SSGS>S	ITPKB_uc001hqh.3_In_Frame_Del_p.92_95SSGS>S	NM_002221	NP_002212	P27987	IP3KB_HUMAN	Homo sapiens inositol-trisphosphate 3-kinase B (ITPKB), mRNA.	92							ATP binding|calmodulin binding|inositol trisphosphate 3-kinase activity	p.A94P(1)|p.V95L(1)		central_nervous_system(1)|endometrium(2)|kidney(4)|large_intestine(4)|lung(13)|ovary(4)|prostate(1)|skin(1)	30		Prostate(94;0.0773)				GCTCACgctactgccgctgctgccgctgc	0.746													---	23	---	---	8	---					
KALRN	8997	broad.mit.edu	37	3	123953675	123953675	+	Splice_Site	DEL	G	-	-			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr3:123953675delG	uc003ehg.3	+	3	270	c.143_splice	c.e3-1	p.G48_splice	KALRN_uc010hrv.1_Splice_Site_p.G48_splice|KALRN_uc003ehf.1_Splice_Site_p.G48_splice|KALRN_uc011bjy.1_Splice_Site_p.G48_splice	NM_001024660	NP_001019831	O60229	KALRN_HUMAN	Homo sapiens kalirin, RhoGEF kinase (KALRN), transcript variant 1, mRNA.	48	CRAL-TRIO.				apoptosis|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|nervous system development|regulation of Rho protein signal transduction|small GTPase mediated signal transduction|vesicle-mediated transport	actin cytoskeleton|cytosol	ATP binding|GTPase activator activity|Rho guanyl-nucleotide exchange factor activity|metal ion binding|protein binding|protein serine/threonine kinase activity			NS(1)|breast(1)|central_nervous_system(1)|cervix(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(21)|lung(28)|ovary(4)|prostate(5)|skin(6)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	83						CCTTCTTGCAGGGGGTCGTGA	0.488													---	4	---	---	2	---					
POU4F2	5458	broad.mit.edu	37	4	147560457	147560458	+	In_Frame_Ins	INS	-	GGC	GGC	rs67907220		TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr4:147560457_147560458insGGC	uc003ikv.3	+	0	413_414	c.165_166insGGC	c.(163-168)insGGC	p.68_69insG		NM_004575	NP_004566	Q12837	PO4F2_HUMAN	Homo sapiens POU class 4 homeobox 2 (POU4F2), mRNA.	68	Poly-Gly.				MAPKKK cascade|estrogen receptor signaling pathway|negative regulation of transcription from RNA polymerase II promoter	nuclear speck	RNA polymerase II core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription			NS(1)|breast(1)|endometrium(7)|kidney(3)|large_intestine(11)|lung(8)|skin(1)|upper_aerodigestive_tract(1)	33	all_hematologic(180;0.151)					ACGCTggtggtggcggcggcgg	0.762													---	4	---	---	2	---					
PURA	5813	broad.mit.edu	37	5	139494456	139494458	+	In_Frame_Del	DEL	CTT	-	-			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr5:139494456_139494458delCTT	uc003lfa.3	+	0	749_751	c.690_692delCTT	c.(688-693)cgcttc>cgc	p.F233del		NM_005859	NP_005850	Q00577	PURA_HUMAN	Homo sapiens purine-rich element binding protein A (PURA), mRNA.	233					DNA unwinding involved in replication|DNA-dependent DNA replication initiation	DNA replication factor A complex	double-stranded telomeric DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|single-stranded DNA binding|transcription factor binding			central_nervous_system(1)|lung(2)|ovary(1)|prostate(1)	5			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			ACAACAAGCGCTTCTTCTTCGAT	0.596													---	4	---	---	21	---					
C6orf223	221416	broad.mit.edu	37	6	43970503	43970504	+	In_Frame_Ins	INS	-	GCG	GCG	rs72369323		TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr6:43970503_43970504insGCG	uc003own.3	+	3	389_390	c.369_370insGCG	c.(367-372)insGCG	p.132_133insA	AK024736_uc003owm.1_Intron|C6orf223_uc003owo.3_3'UTR	NM_153246	NP_694978	Q8N319	CF223_HUMAN	Homo sapiens chromosome 6 open reading frame 223 (C6orf223), transcript variant 1, mRNA.	132	Ala-rich.			A -> AA (in Ref. 2; AAH32706).						central_nervous_system(1)|lung(2)|pancreas(1)|prostate(1)|urinary_tract(1)	6	all_cancers(18;2.28e-07)|all_epithelial(2;1.62e-08)|Lung NSC(15;0.000172)|all_lung(25;0.000533)|Hepatocellular(11;0.00309)|Ovarian(13;0.0437)		all cancers(41;0.00141)|Colorectal(64;0.00337)|COAD - Colon adenocarcinoma(64;0.00536)|STAD - Stomach adenocarcinoma(11;0.217)			CGGTAGAGCGCgcggcggcggc	0.777													---	8	---	---	4	---					
CAMSAP1	157922	broad.mit.edu	37	9	138715799	138715800	+	Frame_Shift_Ins	INS	-	T	T	rs148250832	byFrequency	TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr9:138715799_138715800insT	uc004cgr.4	-	9	1396_1397	c.1396_1397insA	c.(1396-1398)accfs	p.T466fs	CAMSAP1_uc004cgq.4_Frame_Shift_Ins_p.T356fs|CAMSAP1_uc010nbg.3_Frame_Shift_Ins_p.T188fs	NM_015447	NP_056262	Q5T5Y3	CAMP1_HUMAN	Homo sapiens calmodulin regulated spectrin-associated protein 1 (CAMSAP1), mRNA.	466						cytoplasm|microtubule				breast(3)|central_nervous_system(2)|endometrium(6)|kidney(4)|large_intestine(11)|lung(16)|ovary(3)|pancreas(1)|skin(1)	47				OV - Ovarian serous cystadenocarcinoma(145;1.4e-06)|Epithelial(140;1.11e-05)		GACTCACCTGGTTTTTTTTTCT	0.460													---	4	---	---	3	---					
MLEC	9761	broad.mit.edu	37	12	121134166	121134168	+	In_Frame_Del	DEL	GAA	-	-			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr12:121134166_121134168delGAA	uc001tyy.1	+	4	848_850	c.697_699delGAA	c.(697-699)gaadel	p.E238del		NM_014730	NP_055545	Q14165	MLEC_HUMAN	Homo sapiens malectin (MLEC), mRNA.	238	Poly-Glu.				post-translational protein modification|protein N-linked glycosylation via asparagine|protein folding	endoplasmic reticulum membrane|integral to membrane	carbohydrate binding	p.E233E(1)		breast(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(8)|ovary(1)|prostate(1)	16						gaaagaagaggaagaagaagaag	0.458													---	313	---	---	8	---					
ASF1B	55723	broad.mit.edu	37	19	14232424	14232424	+	Frame_Shift_Del	DEL	G	-	-			TCGA-EE-A17Z-06A-11D-A196-08	TCGA-EE-A17Z-10A-01D-A198-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	0f421d6c-acb9-470b-b315-a1f1375a4d1c	0f5f5be4-90e5-4ed4-abd6-595b4fe4806e	g.chr19:14232424delG	uc002mye.3	-	2	494	c.322delC	c.(322-324)cgafs	p.R108fs		NM_018154	NP_060624	Q9NVP2	ASF1B_HUMAN	Homo sapiens ASF1 anti-silencing function 1 homolog B (S. cerevisiae) (ASF1B), mRNA.	108	Interaction with CHAF1B.|Interaction with histone H3 (By similarity).				cell differentiation|chromatin modification|multicellular organismal development|regulation of transcription, DNA-dependent|spermatogenesis|transcription, DNA-dependent	nucleus				endometrium(2)|large_intestine(2)|lung(2)|ovary(1)	7						TAGCCCACTCGGATGAACTCC	0.587													---	35	---	---	22	---					
