Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_status	validation_method	validation_tumor_sample	validation_alt_allele	pox	qox	isArtifactMode	oxoGCut
APITD1	378708	broad.mit.edu	37	1	10494001	10494001	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr1:10494001G>A	uc001are.2	+	2	570	c.154G>A	c.(154-156)GAG>AAG	p.E52K	APITD1_uc001arf.2_Missense_Mutation_p.E52K|APITD1_uc001arg.2_Missense_Mutation_p.G131E|APITD1_uc001arh.2_Missense_Mutation_p.E13K	NM_199294	NP_954988	Q8N2Z9	CENPS_HUMAN	apoptosis-inducing, TAF9-like domain 1 isoform	52					DNA repair|mitotic prometaphase|transcription initiation, DNA-dependent	chromosome, centromeric region|cytosol|Fanconi anaemia nuclear complex	chromatin binding|DNA binding|protein binding			ovary(1)	1	Ovarian(185;0.203)	all_lung(284;1.31e-05)|Lung NSC(185;2.19e-05)|Renal(390;0.000147)|Breast(348;0.00093)|Colorectal(325;0.00205)|Hepatocellular(190;0.00913)|Ovarian(437;0.0228)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;3.31e-07)|COAD - Colon adenocarcinoma(227;7.32e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000297)|Kidney(185;0.000747)|KIRC - Kidney renal clear cell carcinoma(229;0.00258)|STAD - Stomach adenocarcinoma(132;0.0167)|READ - Rectum adenocarcinoma(331;0.0487)		GGCCATTTCGGAGCTGACTTT	0.522													43	125					0	0	0	0
TAS1R2	80834	broad.mit.edu	37	1	19166514	19166514	+	Missense_Mutation	SNP	G	A	A	rs149445409		TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr1:19166514G>A	uc001bba.1	-	6	2100	c.2099C>T	c.(2098-2100)ACG>ATG	p.T700M		NM_152232	NP_689418	Q8TE23	TS1R2_HUMAN	taste receptor, type 1, member 2 precursor	700	Helical; Name=4; (Potential).				detection of chemical stimulus involved in sensory perception of sweet taste	plasma membrane	protein heterodimerization activity|taste receptor activity			skin(2)|ovary(1)|central_nervous_system(1)	4		Colorectal(325;3.46e-05)|all_lung(284;0.000321)|Lung NSC(340;0.000398)|Renal(390;0.000518)|Breast(348;0.000812)|Ovarian(437;0.00764)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.00466)|BRCA - Breast invasive adenocarcinoma(304;3.56e-05)|Kidney(64;0.000177)|KIRC - Kidney renal clear cell carcinoma(64;0.00262)|STAD - Stomach adenocarcinoma(196;0.00644)|READ - Rectum adenocarcinoma(331;0.0649)	Aspartame(DB00168)	ACTGAGGCCCGTGGCCAGCAT	0.562													40	77					0	0	0	0
LPPR4	9890	broad.mit.edu	37	1	99771647	99771647	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr1:99771647G>A	uc001dse.2	+	7	1479	c.1373G>A	c.(1372-1374)CGA>CAA	p.R458Q	LPPR4_uc010oue.1_Missense_Mutation_p.R400Q	NM_014839	NP_055654	Q7Z2D5	LPPR4_HUMAN	plasticity related gene 1	458							phosphatidate phosphatase activity			ovary(3)	3		all_epithelial(167;3.54e-06)|all_lung(203;0.00139)|Lung NSC(277;0.00202)		Epithelial(280;0.0736)|all cancers(265;0.0975)|COAD - Colon adenocarcinoma(174;0.142)|Lung(183;0.201)|Colorectal(170;0.22)		AATGAAAGTCGAAAGTTGTCC	0.493													27	67					0	0	0	0
CDC14A	8556	broad.mit.edu	37	1	100819350	100819350	+	Missense_Mutation	SNP	C	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr1:100819350C>A	uc001dtg.3	+	2	570	c.82C>A	c.(82-84)CCA>ACA	p.P28T	CDC14A_uc009web.2_Intron|CDC14A_uc010oui.1_5'UTR|CDC14A_uc001dte.3_Missense_Mutation_p.P28T|CDC14A_uc001dtf.2_Missense_Mutation_p.P28T|CDC14A_uc009wed.1_5'UTR|CDC14A_uc009wee.2_Missense_Mutation_p.P28T|CDC14A_uc009wec.1_Missense_Mutation_p.P28T	NM_003672	NP_003663	Q9UNH5	CC14A_HUMAN	CDC14 homolog A isoform 1	28	A.				cell cycle|cell division|cell proliferation	centrosome|nucleus|spindle	protein binding|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity			large_intestine(1)	1		all_epithelial(167;3.71e-06)|all_lung(203;0.00097)|Lung NSC(277;0.001)		Epithelial(280;0.0676)|all cancers(265;0.127)|COAD - Colon adenocarcinoma(174;0.201)|Lung(183;0.227)|Colorectal(144;0.241)		AAGGAATAGACCAAAAAGCAC	0.358													7	23					0.000274275	0.00137138	1	0
C1orf125	126859	broad.mit.edu	37	1	179401427	179401427	+	Missense_Mutation	SNP	A	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr1:179401427A>C	uc001gmo.2	+	15	1640	c.1513A>C	c.(1513-1515)AAG>CAG	p.K505Q	C1orf125_uc009wxg.2_RNA|C1orf125_uc001gmn.1_Missense_Mutation_p.K293Q|C1orf125_uc010pnl.1_RNA|C1orf125_uc001gmp.2_Missense_Mutation_p.K505Q	NM_144696	NP_653297	Q5T1B0	AXDN1_HUMAN	hypothetical protein LOC126859 isoform 1	505											0						ATCCCCTAATAAGGGAAATAT	0.308													4	11					0	0	0	0
RGS2	5997	broad.mit.edu	37	1	192780144	192780144	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr1:192780144C>T	uc001gsl.2	+	4	341	c.308C>T	c.(307-309)TCG>TTG	p.S103L		NM_002923	NP_002914	P41220	RGS2_HUMAN	regulator of G-protein signaling 2	103	RGS.|Necessary to inhibit protein synthesis.				cell cycle|negative regulation of cardiac muscle hypertrophy|negative regulation of G-protein coupled receptor protein signaling pathway|negative regulation of MAP kinase activity|negative regulation of phospholipase activity|positive regulation of cardiac muscle contraction|regulation of adrenergic receptor signaling pathway|regulation of translation|relaxation of cardiac muscle	cytosol|internal side of plasma membrane|mitochondrion|nucleolus	calmodulin binding|GTPase activator activity|signal transducer activity				0						TTTTTAAAGTCGGAATTCTGT	0.398													36	88					0	0	0	0
PFKFB2	5208	broad.mit.edu	37	1	207240960	207240960	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr1:207240960G>A	uc001hfg.2	+	9	858	c.749G>A	c.(748-750)CGC>CAC	p.R250H	PFKFB2_uc010psc.1_Missense_Mutation_p.R152H|PFKFB2_uc001hfh.2_Missense_Mutation_p.R250H|PFKFB2_uc009xcc.2_Missense_Mutation_p.R208H|PFKFB2_uc010psd.1_Missense_Mutation_p.R64H	NM_006212	NP_006203	O60825	F262_HUMAN	6-phosphofructo-2-kinase/fructose-2,	250	Fructose-2,6-bisphosphatase.				fructose 2,6-bisphosphate metabolic process|glycolysis	cytosol	6-phosphofructo-2-kinase activity|ATP binding|fructose-2,6-bisphosphate 2-phosphatase activity			ovary(1)	1	Prostate(682;0.19)					GTCCAGCCTCGCACCATTTAC	0.507													50	114					0	0	0	0
KCNK2	3776	broad.mit.edu	37	1	215408401	215408401	+	Silent	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr1:215408401C>T	uc001hkq.2	+	7	1363	c.1194C>T	c.(1192-1194)CCC>CCT	p.P398P	KCNK2_uc001hko.2_Silent_p.P394P|KCNK2_uc009xdm.2_RNA|KCNK2_uc001hkp.2_RNA|KCNK2_uc001hkr.3_Silent_p.P383P	NM_001017425	NP_001017425	O95069	KCNK2_HUMAN	potassium channel, subfamily K, member 2 isoform	398	Cytoplasmic (Potential).|Essential for chloroform and halothane sensitivity (By similarity).|Required for basal channel activity (By similarity).						outward rectifier potassium channel activity				0				OV - Ovarian serous cystadenocarcinoma(81;0.0399)|all cancers(67;0.0556)|GBM - Glioblastoma multiforme(131;0.068)	Dofetilide(DB00204)	TCTTGCCTCCCTTACTGAAGA	0.493													17	37					0	0	0	0
DISC1	27185	broad.mit.edu	37	1	231830106	231830106	+	Missense_Mutation	SNP	G	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr1:231830106G>T	uc001huz.2	+	2	655	c.602G>T	c.(601-603)GGC>GTC	p.G201V	TSNAX-DISC1_uc010pwe.1_Missense_Mutation_p.G156V|TSNAX-DISC1_uc010pwf.1_Missense_Mutation_p.G156V|TSNAX-DISC1_uc010pwg.1_Missense_Mutation_p.G190V|TSNAX-DISC1_uc010pwh.1_Missense_Mutation_p.G156V|TSNAX-DISC1_uc010pwi.1_Missense_Mutation_p.G156V|TSNAX-DISC1_uc010pwj.1_Missense_Mutation_p.G190V|TSNAX-DISC1_uc010pwk.1_Missense_Mutation_p.G190V|TSNAX-DISC1_uc010pwl.1_RNA|DISC1_uc010pwo.1_Missense_Mutation_p.G201V|DISC1_uc010pwp.1_Missense_Mutation_p.G201V|DISC1_uc010pwq.1_Missense_Mutation_p.G201V|DISC1_uc010pwr.1_Missense_Mutation_p.G201V|DISC1_uc010pws.1_Missense_Mutation_p.G201V|DISC1_uc010pwt.1_Missense_Mutation_p.G201V|DISC1_uc010pwu.1_Intron|DISC1_uc010pwv.1_RNA|DISC1_uc010pww.1_Missense_Mutation_p.G201V|DISC1_uc010pwx.1_RNA|DISC1_uc010pwy.1_RNA|DISC1_uc010pwz.1_RNA|DISC1_uc010pxa.1_RNA|DISC1_uc001huy.2_Missense_Mutation_p.G201V|DISC1_uc010pxb.1_Missense_Mutation_p.G201V|DISC1_uc010pxc.1_Missense_Mutation_p.G201V|DISC1_uc010pxd.1_5'UTR|DISC1_uc010pxe.1_Missense_Mutation_p.G201V|DISC1_uc009xfr.2_Missense_Mutation_p.G156V|DISC1_uc010pxf.1_Missense_Mutation_p.G201V|DISC1_uc010pxg.1_Missense_Mutation_p.G201V|DISC1_uc010pxh.1_Missense_Mutation_p.G201V|DISC1_uc010pxi.1_RNA|DISC1_uc010pxj.1_5'UTR|DISC1_uc010pxk.1_RNA|DISC1_uc010pxl.1_RNA|DISC1_uc010pxm.1_Missense_Mutation_p.G201V|DISC1_uc010pxn.1_5'UTR|DISC1_uc001hva.2_Missense_Mutation_p.G201V|DISC1_uc010pwm.1_Missense_Mutation_p.G201V|DISC1_uc001hux.1_Missense_Mutation_p.G201V|DISC1_uc001hvc.3_Missense_Mutation_p.G201V|DISC1_uc010pwn.1_Missense_Mutation_p.G201V	NM_018662	NP_061132	Q9NRI5	DISC1_HUMAN	disrupted in schizophrenia 1 isoform L	201	Interaction with MAP1A.				microtubule cytoskeleton organization|neuron migration|positive regulation of neuroblast proliferation|positive regulation of Wnt receptor signaling pathway|Wnt receptor signaling pathway	centrosome|microtubule	protein binding			skin(1)	1		all_cancers(173;0.0208)|Prostate(94;0.0975)				ACCCCTCCTGGCTCTCACAGT	0.612													9	66					7.48243e-07	3.85125e-06	1	0
RGS7	6000	broad.mit.edu	37	1	240939491	240939491	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr1:240939491C>T	uc001hyv.2	-	18	1766	c.1436G>A	c.(1435-1437)AGG>AAG	p.R479K	RGS7_uc010pyh.1_Intron|RGS7_uc010pyj.1_3'UTR|RGS7_uc001hyu.2_3'UTR|RGS7_uc009xgn.1_3'UTR|RGS7_uc001hyw.2_Missense_Mutation_p.R461K|RGS7_uc010pyi.1_RNA|RGS7_uc001hyt.2_3'UTR	NM_002924	NP_002915	P49802	RGS7_HUMAN	regulator of G-protein signaling 7	Error:Variant_position_missing_in_P49802_after_alignment					G-protein coupled receptor protein signaling pathway|intracellular signal transduction|negative regulation of signal transduction|regulation of G-protein coupled receptor protein signaling pathway	cytoplasm|heterotrimeric G-protein complex	GTPase activator activity|protein binding|signal transducer activity			ovary(4)|skin(2)|kidney(1)	7		all_cancers(173;0.0131)	OV - Ovarian serous cystadenocarcinoma(106;0.027)			GCTTGTTAACCTCTTGGACGT	0.403													4	55					0	0	0	0
RASGEF1A	221002	broad.mit.edu	37	10	43692516	43692516	+	Missense_Mutation	SNP	T	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr10:43692516T>C	uc001jap.1	-	11	1337	c.1256A>G	c.(1255-1257)GAG>GGG	p.E419G	RASGEF1A_uc001jao.1_Missense_Mutation_p.E427G	NM_145313	NP_660356	Q8N9B8	RGF1A_HUMAN	RasGEF domain family, member 1A	419	Ras-GEF.				cell migration|regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	intracellular	Ras guanyl-nucleotide exchange factor activity				0						TGTCATGAACTCATGGATCTG	0.517													13	56					0	0	0	0
OR52M1	119772	broad.mit.edu	37	11	4566851	4566851	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:4566851G>A	uc010qyf.1	+	1	431	c.431G>A	c.(430-432)GGT>GAT	p.G144D		NM_001004137	NP_001004137	Q8NGK5	O52M1_HUMAN	olfactory receptor, family 52, subfamily M,	144	Helical; Name=4; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity				0		Medulloblastoma(188;0.0075)|Breast(177;0.0461)|all_neural(188;0.0577)		Epithelial(150;8.45e-12)|BRCA - Breast invasive adenocarcinoma(625;0.0285)|LUSC - Lung squamous cell carcinoma(625;0.19)		ACAGTGGTGGGTCGTTTGGGG	0.522													28	60					0	0	0	0
OR51A4	401666	broad.mit.edu	37	11	4967421	4967421	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:4967421C>T	uc010qys.1	-	1	910	c.910G>A	c.(910-912)GTT>ATT	p.V304I		NM_001005329	NP_001005329	Q8NGJ6	O51A4_HUMAN	olfactory receptor, family 51, subfamily A,	304	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(2)|skin(1)	3		Medulloblastoma(188;0.0075)|all_neural(188;0.0577)|Breast(177;0.086)		Epithelial(150;3.22e-11)|BRCA - Breast invasive adenocarcinoma(625;0.0284)|LUSC - Lung squamous cell carcinoma(625;0.19)		TTTGCTACAACTCTCACTCTA	0.353													28	254					0	0	0	0
NAV2	89797	broad.mit.edu	37	11	19735323	19735323	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:19735323C>T	uc010rdm.1	+	1	443	c.82C>T	c.(82-84)CCC>TCC	p.P28S	NAV2_uc001mpp.2_Intron|NAV2_uc001mpr.3_Missense_Mutation_p.P28S|LOC100126784_uc010rdl.1_3'UTR	NM_145117	NP_660093	Q8IVL1	NAV2_HUMAN	neuron navigator 2 isoform 2	28						nucleus	ATP binding|helicase activity			skin(4)|ovary(1)|pancreas(1)	6						CCTGCACGTgcccccggcccg	0.547													7	25					0	0	0	0
EHF	26298	broad.mit.edu	37	11	34673089	34673089	+	Missense_Mutation	SNP	A	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:34673089A>T	uc001mvr.1	+	5	518	c.407A>T	c.(406-408)GAG>GTG	p.E136V	EHF_uc009yke.1_Missense_Mutation_p.E136V|EHF_uc009ykf.1_Missense_Mutation_p.E139V	NM_012153	NP_036285	Q9NZC4	EHF_HUMAN	ets homologous factor	136					cell proliferation|epithelial cell differentiation|multicellular organismal development|positive regulation of transcription, DNA-dependent		protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity				0		all_hematologic(20;0.117)	Epithelial(1;0.055)|all cancers(1;0.137)|STAD - Stomach adenocarcinoma(6;0.235)			TTTTTTGTAGAGCCTTCCATC	0.423													20	41					0	0	0	0
SPI1	6688	broad.mit.edu	37	11	47381575	47381575	+	Missense_Mutation	SNP	G	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:47381575G>C	uc001nfc.1	-	3	382	c.159C>G	c.(157-159)TTC>TTG	p.F53L	SPI1_uc001nfb.1_Missense_Mutation_p.F54L|SLC39A13_uc001nfd.2_Intron|SPI1_uc009ylp.1_Missense_Mutation_p.F47L	NM_003120	NP_003111	P17947	SPI1_HUMAN	hematopoietic transcription factor PU.1 isoform	53					negative regulation of transcription from RNA polymerase II promoter|positive regulation of transcription, DNA-dependent|regulation of erythrocyte differentiation	nucleus	protein binding|RNA binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			lung(1)|central_nervous_system(1)	2				Lung(87;0.0967)		GGTGGGGGTGGAAGTCCCAGT	0.582													6	6					0	0	0	0
OR8J1	219477	broad.mit.edu	37	11	56128447	56128447	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:56128447C>T	uc010rjh.1	+	1	725	c.725C>T	c.(724-726)GCT>GTT	p.A242V		NM_001005205	NP_001005205	Q8NGP2	OR8J1_HUMAN	olfactory receptor, family 8, subfamily J,	242	Helical; Name=6; (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(2)	2	Esophageal squamous(21;0.00448)					TCTACCTGTGCTTCACATATG	0.348													35	69					0	0	0	0
SF3B2	10992	broad.mit.edu	37	11	65826722	65826722	+	Silent	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:65826722C>T	uc001ogy.1	+	11	1273	c.1233C>T	c.(1231-1233)GAC>GAT	p.D411D		NM_006842	NP_006833	Q13435	SF3B2_HUMAN	splicing factor 3B subunit 2	411					interspecies interaction between organisms	catalytic step 2 spliceosome|nucleoplasm|U12-type spliceosomal complex	nucleic acid binding|protein binding			ovary(2)|breast(1)	3						AGAAACTTGACAAACTGGAGA	0.532													10	27					0	0	0	0
INPPL1	3636	broad.mit.edu	37	11	71939892	71939892	+	Splice_Site	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:71939892G>A	uc001osf.2	+	4	665	c.518_splice	c.e4+1	p.S173_splice	INPPL1_uc001osg.2_Splice_Site	NM_001567	NP_001558	O15357	SHIP2_HUMAN	inositol polyphosphate phosphatase-like 1						actin filament organization|cell adhesion|endocytosis	actin cortical patch|cytosol	actin binding|SH2 domain binding|SH3 domain binding			skin(2)|ovary(1)|breast(1)	4						CTGCTGAGAGGTGAGACCCCC	0.627													21	44					0	0	0	0
USP35	57558	broad.mit.edu	37	11	77924730	77924730	+	Silent	SNP	C	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:77924730C>A	uc009yva.1	+	11	3174	c.2928C>A	c.(2926-2928)ATC>ATA	p.I976I	USP35_uc001ozc.2_Silent_p.I544I|USP35_uc010rsp.1_Silent_p.I408I|USP35_uc001ozd.2_Silent_p.I587I|USP35_uc001ozf.2_Silent_p.I707I	NM_020798	NP_065849	Q9P2H5	UBP35_HUMAN	ubiquitin specific protease 35	976					ubiquitin-dependent protein catabolic process		binding|cysteine-type peptidase activity|ubiquitin thiolesterase activity			lung(2)|ovary(1)	3	all_cancers(14;3.77e-18)|all_epithelial(13;6.16e-21)|Breast(9;5.6e-16)|Ovarian(111;0.152)		OV - Ovarian serous cystadenocarcinoma(8;1.04e-25)			CGGCCTACATCTCTGCACTCC	0.577													19	53					4.96729e-08	2.61436e-07	1	0
FAT3	120114	broad.mit.edu	37	11	92085482	92085482	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:92085482G>A	uc001pdj.3	+	1	221	c.204G>A	c.(202-204)ATG>ATA	p.M68I		NM_001008781	NP_001008781	Q8TDW7	FAT3_HUMAN	FAT tumor suppressor homolog 3	68	Cadherin 1.|Extracellular (Potential).				homophilic cell adhesion|multicellular organismal development	integral to membrane|plasma membrane	calcium ion binding			ovary(4)|pancreas(1)	5		Acute lymphoblastic leukemia(157;3.01e-05)|all_hematologic(158;0.00858)				AGAGTAGAATGGGCATCACCT	0.458										TCGA Ovarian(4;0.039)			16	48					0	0	0	0
SLC36A4	120103	broad.mit.edu	37	11	92901243	92901243	+	Missense_Mutation	SNP	T	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:92901243T>C	uc001pdn.2	-	7	732	c.635A>G	c.(634-636)TAT>TGT	p.Y212C	SLC36A4_uc001pdm.2_Missense_Mutation_p.Y77C	NM_152313	NP_689526	Q6YBV0	S36A4_HUMAN	solute carrier family 36 (proton/amino acid	212	Helical; (Potential).				L-alanine transport|proline transport|tryptophan transport	integral to membrane	symporter activity			ovary(2)|upper_aerodigestive_tract(1)	3		Acute lymphoblastic leukemia(157;2.26e-05)|all_hematologic(158;0.0123)				GCAAAGCATATATATCCTTAG	0.353													19	47					0	0	0	0
JRKL	8690	broad.mit.edu	37	11	96125222	96125222	+	Missense_Mutation	SNP	T	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:96125222T>G	uc009ywu.2	+	2	1661	c.1409T>G	c.(1408-1410)CTA>CGA	p.L470R	CCDC82_uc001pfx.3_5'Flank|CCDC82_uc009ywr.2_5'Flank|CCDC82_uc009ywt.1_5'Flank|JRKL_uc001pfy.2_Missense_Mutation_p.L470R	NM_003772	NP_003763	Q9Y4A0	JERKL_HUMAN	jerky homolog-like	470					central nervous system development|regulation of transcription, DNA-dependent	chromosome, centromeric region|nucleus	DNA binding				0		Acute lymphoblastic leukemia(157;2.31e-05)|all_hematologic(158;0.00824)		BRCA - Breast invasive adenocarcinoma(274;0.148)		GAAATAGAACTAATTCCAGAG	0.398													5	22					0	0	0	0
ROBO4	54538	broad.mit.edu	37	11	124756427	124756427	+	Silent	SNP	G	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr11:124756427G>T	uc001qbg.2	-	16	2867	c.2727C>A	c.(2725-2727)GCC>GCA	p.A909A	ROBO4_uc010sas.1_Silent_p.A764A|ROBO4_uc001qbh.2_3'UTR|ROBO4_uc001qbi.2_Silent_p.A467A	NM_019055	NP_061928	Q8WZ75	ROBO4_HUMAN	roundabout homolog 4, magic roundabout	909					angiogenesis|cell differentiation	integral to membrane	receptor activity			ovary(1)|skin(1)	2	all_hematologic(175;0.215)	Medulloblastoma(222;0.0523)|Lung NSC(97;0.118)|all_lung(97;0.126)|Breast(109;0.171)|all_neural(223;0.224)		BRCA - Breast invasive adenocarcinoma(274;1.5e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0301)		CCACTGCCAGGGCCCGGGCAA	0.602													8	39					5.18039e-06	2.62773e-05	1	0
FKBP4	2288	broad.mit.edu	37	12	2907902	2907902	+	Missense_Mutation	SNP	C	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr12:2907902C>A	uc001qkz.2	+	4	622	c.424C>A	c.(424-426)CTG>ATG	p.L142M		NM_002014	NP_002005	Q02790	FKBP4_HUMAN	FK506 binding protein 52	142					negative regulation of microtubule polymerization or depolymerization|negative regulation of neuron projection development|protein folding	axonal growth cone|cytosol|membrane|microtubule|nucleus	FK506 binding|heat shock protein binding|peptidyl-prolyl cis-trans isomerase activity|protein binding, bridging				0			OV - Ovarian serous cystadenocarcinoma(31;0.00105)		Dimethyl sulfoxide(DB01093)	GGGAGAAGATCTGACGGAAGA	0.463													49	148					5.57489e-27	3.25202e-26	1	0
GALNT8	26290	broad.mit.edu	37	12	4854675	4854675	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr12:4854675C>T	uc001qne.1	+	5	1033	c.941C>T	c.(940-942)ACC>ATC	p.T314I		NM_017417	NP_059113	Q9NY28	GALT8_HUMAN	polypeptide N-acetylgalactosaminyltransferase 8	314	Lumenal (Potential).					Golgi membrane|integral to membrane	polypeptide N-acetylgalactosaminyltransferase activity|sugar binding			ovary(2)|pancreas(1)|skin(1)	4						CGTTTTGACACCTTCAAACTG	0.488													23	69					0	0	0	0
KCNA1	3736	broad.mit.edu	37	12	5021157	5021157	+	Missense_Mutation	SNP	A	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr12:5021157A>T	uc001qnh.2	+	2	1718	c.613A>T	c.(613-615)ATC>TTC	p.I205F		NM_000217	NP_000208	Q09470	KCNA1_HUMAN	potassium voltage-gated channel subfamily A	205					synaptic transmission	juxtaparanode region of axon|voltage-gated potassium channel complex	delayed rectifier potassium channel activity|potassium ion transmembrane transporter activity			ovary(1)|skin(1)	2					Desflurane(DB01189)|Enflurane(DB00228)|Isoflurane(DB00753)|Methoxyflurane(DB01028)|Sevoflurane(DB01236)	CGTCCACCGCATCGACAACAC	0.537													19	48					0	0	0	0
LOC653113	653113	broad.mit.edu	37	12	8384397	8384397	+	RNA	SNP	C	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr12:8384397C>G	uc010sgk.1	-	5		c.1391G>C				NR_024254				Homo sapiens family with sequence similarity 86, member A pseudogene (LOC653113), non-coding RNA.												0						CCCCAGGGCCCCTGCTGTCCT	0.587													3	34					0	0	0	0
PRB1	5542	broad.mit.edu	37	12	11506558	11506558	+	Missense_Mutation	SNP	C	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr12:11506558C>A	uc001qzw.1	-	4	516	c.479G>T	c.(478-480)GGA>GTA	p.G160V	PRB1_uc001qzu.1_Intron|PRB1_uc001qzv.1_Intron	NM_005039	NP_005030	P04280	PRP1_HUMAN	proline-rich protein BstNI subfamily 1 isoform 1	221	9.|15 X 20 AA approximate tandem repeats of P-P-G-K-P-Q-G-P-P-[PAQ]-Q-[GE]-[GD]- [NKS]-[KSQRN]-[PRQS]-[QS] [GPS]-[PQAR]- [PSR].		Missing (in clone CP-4).|Missing (in clone CP-5).|Missing (in allele S).			extracellular region					0			OV - Ovarian serous cystadenocarcinoma(49;0.185)			TGGGGGTGGTCCTTGTGGCTT	0.602													15	45					7.38237e-10	3.97512e-09	1	0
PRB2	653247	broad.mit.edu	37	12	11546653	11546653	+	Missense_Mutation	SNP	C	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr12:11546653C>A	uc010shk.1	-	3	394	c.359G>T	c.(358-360)GGA>GTA	p.G120V		NM_006248	NP_006239			proline-rich protein BstNI subfamily 2												0		all_cancers(2;0.00558)|Acute lymphoblastic leukemia(2;3.94e-11)|all_hematologic(2;3.6e-09)	OV - Ovarian serous cystadenocarcinoma(49;0.185)			TGGGGGTGGTCCTTGTGGCTT	0.597													32	713					6.90743e-12	3.7775e-11	1	0
MRPS35	60488	broad.mit.edu	37	12	27888432	27888432	+	Missense_Mutation	SNP	A	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr12:27888432A>C	uc001rih.2	+	6	623	c.575A>C	c.(574-576)AAA>ACA	p.K192T	MRPS35_uc001rii.2_Intron	NM_021821	NP_068593	P82673	RT35_HUMAN	mitochondrial ribosomal protein S35 precursor	192					DNA damage response, detection of DNA damage	mitochondrial small ribosomal subunit					0	Lung SC(9;0.0873)					AAATTAATTAAACTTGTAGGA	0.323													22	54					0	0	0	0
KRT4	3851	broad.mit.edu	37	12	53201426	53201426	+	Splice_Site	SNP	A	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr12:53201426A>G	uc001saz.2	-	7	1839	c.1568_splice	c.e7+1	p.R523_splice		NM_002272	NP_002263	B4DRS2	B4DRS2_HUMAN	keratin 4							keratin filament	structural molecule activity			ovary(4)|skin(2)	6						CTAACCCCTCACCTGTACTCC	0.582													31	57					0	0	0	0
GALNT4	8693	broad.mit.edu	37	12	89917883	89917883	+	Missense_Mutation	SNP	C	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr12:89917883C>A	uc001tbd.2	-	1	653	c.444G>T	c.(442-444)TGG>TGT	p.W148C	POC1B_uc001tba.2_Intron|POC1B_uc001tbb.2_Intron|POC1B_uc001tbc.2_Intron|POC1B_uc010sun.1_Intron|GALNT4_uc001tbe.2_Missense_Mutation_p.W145C|GALNT4_uc010suo.1_Intron	NM_003774	NP_003765	Q8N4A0	GALT4_HUMAN	polypeptide N-acetylgalactosaminyltransferase 4	148	Lumenal (Potential).|Catalytic subdomain A.				carbohydrate metabolic process	Golgi membrane|integral to membrane|perinuclear region of cytoplasm	polypeptide N-acetylgalactosaminyltransferase activity|sugar binding				0						GCAAAGTCGACCAGGCTTCGT	0.398											OREG0022018	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	18	45					1.33834e-09	7.09724e-09	1	0
ACTR6	64431	broad.mit.edu	37	12	100604114	100604114	+	Missense_Mutation	SNP	A	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr12:100604114A>T	uc001thb.1	+	6	613	c.557A>T	c.(556-558)GAG>GTG	p.E186V	ACTR6_uc001thc.1_Missense_Mutation_p.E78V|ACTR6_uc001thd.1_Missense_Mutation_p.E186V|ACTR6_uc009ztu.1_5'UTR|ACTR6_uc001the.1_Missense_Mutation_p.E104V|ACTR6_uc001thf.1_Missense_Mutation_p.E104V|uc001thg.1_Intron	NM_022496	NP_071941	Q9GZN1	ARP6_HUMAN	ARP6 actin-related protein 6 homolog	186						cytoplasm|cytoskeleton				ovary(1)	1						CATCTAAAGGAGATCATATCT	0.358													33	75					0	0	0	0
NCOR2	9612	broad.mit.edu	37	12	124979778	124979778	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr12:124979778G>A	uc010tba.1	-	1	137	c.20C>T	c.(19-21)CCT>CTT	p.P7L	NCOR2_uc010tay.1_Missense_Mutation_p.P7L|NCOR2_uc010taz.1_Missense_Mutation_p.P7L|NCOR2_uc010tbb.1_Missense_Mutation_p.P7L|NCOR2_uc010tbc.1_Missense_Mutation_p.P7L|NCOR2_uc001ugj.1_Missense_Mutation_p.P7L|NCOR2_uc001ugk.1_Missense_Mutation_p.P7L	NM_001077261	NP_001070729	Q9Y618	NCOR2_HUMAN	nuclear receptor co-repressor 2 isoform 2	7				P -> L (in Ref. 2; AAD20946).	cellular lipid metabolic process|negative regulation of transcription from RNA polymerase II promoter|regulation of cellular ketone metabolic process by negative regulation of transcription from an RNA polymerase II promoter|transcription, DNA-dependent	nuclear body|nucleus|transcriptional repressor complex	DNA binding|histone deacetylase binding|Notch binding|protein N-terminus binding|transcription corepressor activity			skin(3)|ovary(1)	4	all_neural(191;0.0804)|Medulloblastoma(191;0.163)			Epithelial(86;3.99e-05)|OV - Ovarian serous cystadenocarcinoma(86;9.14e-05)|all cancers(50;0.000402)|BRCA - Breast invasive adenocarcinoma(302;0.0764)		CTGTGCCACAGGCTGTGTGGA	0.627													5	29					0	0	0	0
LOC374491	374491	broad.mit.edu	37	13	25161397	25161397	+	RNA	SNP	C	G	G	rs3874227	by1000genomes	TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr13:25161397C>G	uc001upm.2	+	8		c.921C>G			LOC374491_uc001upn.2_RNA|LOC374491_uc001upo.2_RNA					Homo sapiens mRNA; cDNA DKFZp434J0717 (from clone DKFZp434J0717).												0						TGAAACATCTCTACAACTGGA	0.343													6	23					0	0	0	0
KIAA1704	55425	broad.mit.edu	37	13	45580367	45580367	+	Silent	SNP	T	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr13:45580367T>C	uc001uzq.2	+	3	355	c.252T>C	c.(250-252)GAT>GAC	p.D84D	KIAA1704_uc010tfo.1_RNA|KIAA1704_uc001uzr.1_Silent_p.D84D|KIAA1704_uc001uzs.2_5'UTR|KIAA1704_uc001uzt.2_5'UTR	NM_018559	NP_061029	Q8IXQ4	K1704_HUMAN	hypothetical protein LOC55425	84	Poly-Asp.									pancreas(1)|skin(1)	2		Lung NSC(96;0.00143)|Prostate(109;0.0137)|Breast(139;0.0192)|Lung SC(185;0.0367)|Hepatocellular(98;0.133)	KIRC - Kidney renal clear cell carcinoma(16;0.234)	GBM - Glioblastoma multiforme(144;0.000313)|BRCA - Breast invasive adenocarcinoma(63;0.126)		atgatgacgatgatgatgatg	0.289													4	175					0	0	0	0
LCP1	3936	broad.mit.edu	37	13	46716466	46716466	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr13:46716466C>T	uc001vaz.3	-	13	1589	c.1463G>A	c.(1462-1464)CGC>CAC	p.R488H	LCP1_uc010ack.2_Missense_Mutation_p.R57H|LCP1_uc001vay.3_Missense_Mutation_p.R85H|LCP1_uc001vba.3_Missense_Mutation_p.R488H	NM_002298	NP_002289	P13796	PLSL_HUMAN	L-plastin	488	Actin-binding 2.|CH 3.				regulation of intracellular protein transport|T cell activation involved in immune response	cell junction|cytosol|ruffle membrane	calcium ion binding			lung(4)|ovary(3)	7		Lung NSC(96;1.27e-05)|Breast(56;8.04e-05)|Prostate(109;0.00217)|Hepatocellular(98;0.0207)|Lung SC(185;0.0262)	KIRC - Kidney renal clear cell carcinoma(16;0.234)	GBM - Glioblastoma multiforme(144;5.39e-05)		TGTGAGAGTGCGGTTTCCTTC	0.413			T	BCL6	NHL 								16	97					0	0	0	0
OR11H12	440153	broad.mit.edu	37	14	19378056	19378056	+	Missense_Mutation	SNP	C	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr14:19378056C>A	uc010tkp.1	+	1	463	c.463C>A	c.(463-465)CTC>ATC	p.L155I		NM_001013354	NP_001013372	B2RN74	O11HC_HUMAN	olfactory receptor, family 11, subfamily H,	155	Cytoplasmic (Potential).				sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			ovary(2)	2	all_cancers(95;0.00108)		Epithelial(56;9.96e-07)|all cancers(55;2.95e-06)	GBM - Glioblastoma multiforme(265;0.00327)		GACTGGGCATCTCTGTGCCAA	0.473													34	436					3.62531e-18	2.06318e-17	1	0
OXA1L	5018	broad.mit.edu	37	14	23240279	23240279	+	Missense_Mutation	SNP	C	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr14:23240279C>A	uc001wgn.2	+	8	1172	c.1172C>A	c.(1171-1173)TCC>TAC	p.S391Y	OXA1L_uc001wgo.2_RNA|OXA1L_uc010akc.2_Missense_Mutation_p.S391Y|OXA1L_uc001wgp.2_Missense_Mutation_p.S315Y|OXA1L_uc001wgq.2_Missense_Mutation_p.S95Y	NM_005015	NP_005006	Q15070	OXA1L_HUMAN	oxidase (cytochrome c) assembly 1-like	331	Mitochondrial matrix (Potential).				aerobic respiration|mitochondrial proton-transporting ATP synthase complex assembly|mitochondrial respiratory chain complex I assembly|negative regulation of ATPase activity|negative regulation of oxidoreductase activity|protein insertion into membrane|protein tetramerization	integral to mitochondrial membrane|mitochondrial respiratory chain|protein complex	protein homodimerization activity|ribosome binding			central_nervous_system(1)	1	all_cancers(95;8.44e-05)			GBM - Glioblastoma multiforme(265;0.0096)		GTCCAAGTATCCTGTCTCCGG	0.507													51	105					2.69953e-25	1.56171e-24	1	0
KIAA1737	85457	broad.mit.edu	37	14	77579969	77579969	+	Missense_Mutation	SNP	A	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr14:77579969A>G	uc001xtd.2	+	4	687	c.508A>G	c.(508-510)AGG>GGG	p.R170G	KIAA1737_uc001xtc.1_Missense_Mutation_p.R72G	NM_033426	NP_219494	Q9C0C6	K1737_HUMAN	KIAA1737 protein	170											0			Kidney(204;0.164)	BRCA - Breast invasive adenocarcinoma(234;0.0284)		TCCAGGCAAAAGGGGCCTTTC	0.488													3	105					0	0	0	0
Unknown	0	broad.mit.edu	37	15	20644856	20644856	+	Missense_Mutation	SNP	T	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr15:20644856T>G	uc001ytg.2	-	21	3111	c.2402A>C	c.(2401-2403)GAA>GCA	p.E801A	uc010tyx.1_RNA|uc001yth.3_Missense_Mutation_p.E801A|uc010tyy.1_Missense_Mutation_p.E801A					RecName: Full=Putative HERC2-like protein 3;																		CCTCGCCCTTTCGGTCTTGTC	0.448													6	27					0	0	0	0
FAM98B	283742	broad.mit.edu	37	15	38773633	38773633	+	Silent	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr15:38773633G>A	uc001zkb.1	+	7	905	c.870G>A	c.(868-870)CGG>CGA	p.R290R	FAM98B_uc001zkc.2_Silent_p.R290R	NM_001042429	NP_001035894	Q52LJ0	FA98B_HUMAN	family with sequence similarity 98, member B	290						tRNA-splicing ligase complex	protein binding			ovary(1)	1		all_cancers(109;3.11e-17)|all_epithelial(112;2.64e-15)|Lung NSC(122;2.11e-11)|all_lung(180;5.61e-10)|Melanoma(134;0.0574)		GBM - Glioblastoma multiforme(113;9e-08)|BRCA - Breast invasive adenocarcinoma(123;0.0209)		GCACCAGCCGGGAGAAGACCG	0.398													11	48					0	0	0	0
FBN1	2200	broad.mit.edu	37	15	48784730	48784730	+	Missense_Mutation	SNP	T	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr15:48784730T>G	uc001zwx.1	-	24	3110	c.2782A>C	c.(2782-2784)AAC>CAC	p.N928H		NM_000138	NP_000129	P35555	FBN1_HUMAN	fibrillin 1 precursor	928	EGF-like 14; calcium-binding.				heart development|negative regulation of BMP signaling pathway by extracellular sequestering of BMP|negative regulation of transforming growth factor beta receptor signaling pathway by extracellular sequestering of TGFbeta|skeletal system development	basement membrane|extracellular space|microfibril	calcium ion binding|extracellular matrix structural constituent|protein binding			ovary(2)|large_intestine(1)	3		all_lung(180;0.00279)		all cancers(107;4.24e-07)|GBM - Glioblastoma multiforme(94;1.41e-05)		CCCCTAGTGTTAACACACAGG	0.348													8	36					0	0	0	0
SNX33	257364	broad.mit.edu	37	15	75941779	75941779	+	Missense_Mutation	SNP	T	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr15:75941779T>G	uc002bau.2	+	1	432	c.336T>G	c.(334-336)GAT>GAG	p.D112E	IMP3_uc002bat.2_5'Flank|SNX33_uc002bav.2_5'Flank	NM_153271	NP_695003	Q8WV41	SNX33_HUMAN	sorting nexin 33	112	Poly-Asp.				cell communication		phosphatidylinositol binding|protein binding			ovary(1)	1						TTGAGGAGGATGATGATGATG	0.622													3	100					0	0	0	0
Unknown	0	broad.mit.edu	37	15	84909434	84909434	+	RNA	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr15:84909434G>A	uc010bmy.1	+	1		c.61G>A								Homo sapiens golgi autoantigen, golgin subfamily a, 9 pseudogene, mRNA (cDNA clone IMAGE:40024530).																		GAGAGGCTGCGGGAGCTGGAG	0.667													3	7					0	0	0	0
NTRK3	4916	broad.mit.edu	37	15	88678559	88678559	+	Missense_Mutation	SNP	C	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr15:88678559C>A	uc002bme.1	-	9	1139	c.977G>T	c.(976-978)CGT>CTT	p.R326L	NTRK3_uc002bmh.2_Missense_Mutation_p.R326L|NTRK3_uc002bmf.1_Missense_Mutation_p.R326L|NTRK3_uc010upl.1_Missense_Mutation_p.R228L|NTRK3_uc010bnh.1_Missense_Mutation_p.R326L|NTRK3_uc002bmg.2_Missense_Mutation_p.R326L	NM_001012338	NP_001012338	Q16288	NTRK3_HUMAN	neurotrophic tyrosine kinase, receptor, type 3	326	Ig-like C2-type 2.|Extracellular (Potential).				transmembrane receptor protein tyrosine kinase signaling pathway	integral to plasma membrane	ATP binding|transmembrane receptor protein tyrosine kinase activity		ETV6/NTRK3(234)	soft_tissue(85)|kidney(66)|breast(56)|salivary_gland(26)|lung(22)|large_intestine(6)|ovary(6)|stomach(5)|central_nervous_system(3)|pancreas(3)|haematopoietic_and_lymphoid_tissue(2)|skin(1)	281			BRCA - Breast invasive adenocarcinoma(143;0.211)			GGGGTTGCCACGCACCACAAA	0.592			T	ETV6	congenital fibrosarcoma|Secretory breast 					TSP Lung(13;0.10)			22	38					5.26018e-13	2.92232e-12	1	0
CDH8	1006	broad.mit.edu	37	16	61687669	61687669	+	Missense_Mutation	SNP	C	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr16:61687669C>A	uc002eog.1	-	12	2495	c.2243G>T	c.(2242-2244)GGC>GTC	p.G748V		NM_001796	NP_001787	P55286	CADH8_HUMAN	cadherin 8, type 2 preproprotein	748	Cytoplasmic (Potential).				adherens junction organization|cell junction assembly|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(6)|skin(2)|breast(1)	9		Ovarian(137;0.0799)|Melanoma(118;0.16)		UCEC - Uterine corpus endometrioid carcinoma (183;0.196)|Epithelial(162;0.0155)|all cancers(182;0.0305)|OV - Ovarian serous cystadenocarcinoma(108;0.0499)|BRCA - Breast invasive adenocarcinoma(181;0.249)		GCCTTCATAGCCATATATCTG	0.502													14	45					6.72482e-11	3.64913e-10	1	0
CDH16	1014	broad.mit.edu	37	16	66947070	66947070	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr16:66947070C>T	uc002eql.2	-	9	1091	c.1018G>A	c.(1018-1020)GAC>AAC	p.D340N	CDH16_uc010cdy.2_Missense_Mutation_p.D340N|CDH16_uc002eqm.2_Missense_Mutation_p.D243N	NM_004062	NP_004053	O75309	CAD16_HUMAN	cadherin 16 precursor	340	Extracellular (Potential).				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(2)|upper_aerodigestive_tract(1)	3		Ovarian(137;0.0563)		OV - Ovarian serous cystadenocarcinoma(108;0.0877)|Epithelial(162;0.203)		ACTGTGGGGTCACGGGGAGGG	0.587													33	118					0	0	0	0
CDH3	1001	broad.mit.edu	37	16	68732227	68732227	+	Missense_Mutation	SNP	A	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr16:68732227A>G	uc002ewf.2	+	16	3546	c.2414A>G	c.(2413-2415)GAT>GGT	p.D805G	CDH3_uc010vli.1_Missense_Mutation_p.D750G	NM_001793	NP_001784	P22223	CADH3_HUMAN	cadherin 3, type 1 preproprotein	805	Cytoplasmic (Potential).				adherens junction organization|cell junction assembly|homophilic cell adhesion|response to stimulus|visual perception	integral to membrane	calcium ion binding	p.?(1)		ovary(3)|breast(1)|skin(1)	5		Ovarian(137;0.0564)		OV - Ovarian serous cystadenocarcinoma(108;0.000782)|Epithelial(162;0.0054)|all cancers(182;0.0384)		CAAGACCAAGATTACGATTAT	0.642													34	112					0	0	0	0
PKD1L2	114780	broad.mit.edu	37	16	81145910	81145910	+	Missense_Mutation	SNP	A	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr16:81145910A>T	uc002fgh.1	-	42	6842	c.6842T>A	c.(6841-6843)CTC>CAC	p.L2281H	PKD1L2_uc002fgf.1_Missense_Mutation_p.L81H|PKD1L2_uc002fgg.1_RNA	NM_052892	NP_443124	Q7Z442	PK1L2_HUMAN	polycystin 1-like 2 isoform a	2281	Helical; (Potential).				neuropeptide signaling pathway	integral to membrane	calcium ion binding|ion channel activity|sugar binding			ovary(1)|central_nervous_system(1)|pancreas(1)	3						TGTGGACAGGAGTACCAGGAA	0.547													11	82					0	0	0	0
FXR2	9513	broad.mit.edu	37	17	7497597	7497597	+	Nonsense_Mutation	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr17:7497597G>A	uc002gia.1	-	10	1206	c.979C>T	c.(979-981)CGA>TGA	p.R327*	FXR2_uc010vud.1_Nonsense_Mutation_p.R327*	NM_004860	NP_004851	P51116	FXR2_HUMAN	fragile X mental retardation syndrome related	327						cytosolic large ribosomal subunit	protein binding|RNA binding				0				READ - Rectum adenocarcinoma(115;0.17)		CCTTCCACTCGAACCCTCACC	0.468													6	24					0	0	0	0
TP53	7157	broad.mit.edu	37	17	7578520	7578520	+	Missense_Mutation	SNP	A	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr17:7578520A>T	uc002gim.2	-	5	604	c.410T>A	c.(409-411)CTG>CAG	p.L137Q	TP53_uc002gig.1_Missense_Mutation_p.L137Q|TP53_uc002gih.2_Missense_Mutation_p.L137Q|TP53_uc010cne.1_5'Flank|TP53_uc010cnf.1_Missense_Mutation_p.L5Q|TP53_uc010cng.1_Missense_Mutation_p.L5Q|TP53_uc002gii.1_Missense_Mutation_p.L5Q|TP53_uc010cnh.1_Missense_Mutation_p.L137Q|TP53_uc010cni.1_Missense_Mutation_p.L137Q|TP53_uc002gij.2_Missense_Mutation_p.L137Q|TP53_uc010cnj.1_RNA|TP53_uc002gin.2_Missense_Mutation_p.L44Q|TP53_uc002gio.2_Missense_Mutation_p.L5Q|TP53_uc010vug.1_Missense_Mutation_p.L98Q	NM_001126112	NP_001119584	P04637	P53_HUMAN	tumor protein p53 isoform a	137	Required for interaction with FBXO42.||Interaction with HIPK1 (By similarity).|Interaction with AXIN1 (By similarity).		L -> M (in sporadic cancers; somatic mutation).|L -> V (in sporadic cancers; somatic mutation).|L -> P (in sporadic cancers; somatic mutation).|L -> Q (in sporadic cancers; somatic mutation).		activation of caspase activity by cytochrome c|base-excision repair|blood coagulation|cell cycle arrest|cell differentiation|cell proliferation|cellular protein localization|cellular response to drug|cellular response to glucose starvation|cellular response to hypoxia|cellular response to ionizing radiation|cellular response to UV|determination of adult lifespan|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|ER overload response|interspecies interaction between organisms|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of helicase activity|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|nucleotide-excision repair|oxidative stress-induced premature senescence|positive regulation of histone deacetylation|positive regulation of neuron apoptosis|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of reactive oxygen species metabolic process|positive regulation of thymocyte apoptosis|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase II promoter|protein localization|protein tetramerization|Ras protein signal transduction|regulation of mitochondrial membrane permeability|replicative senescence|response to antibiotic|response to gamma radiation|response to X-ray	cytoplasm|cytosol|endoplasmic reticulum|insoluble fraction|mitochondrion|nuclear chromatin|nuclear matrix|nucleolus|nucleus|PML body|protein complex|replication fork	ATP binding|chaperone binding|chromatin binding|copper ion binding|damaged DNA binding|DNA strand annealing activity|histone acetyltransferase binding|p53 binding|protease binding|protein binding|protein heterodimerization activity|protein kinase binding|protein N-terminus binding|protein phosphatase 2A binding|RNA polymerase II transcription factor binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|transcription regulatory region DNA binding|transcription repressor activity|ubiquitin protein ligase binding|zinc ion binding	p.0?(7)|p.L137L(6)|p.L137P(3)|p.N131fs*27(2)|p.L137Q(2)|p.L137M(2)|p.V73fs*9(1)|p.L137_W146del10(1)|p.C135_T140delCQLAKT(1)|p.L137_A138insX(1)|p.L137fs*12(1)|p.C135_A138delCQLA(1)|p.K132_A138delKMFCQLA(1)|p.F134_T140>S(1)|p.Q136_K139delQLAK(1)|p.L137fs*33(1)|p.L137V(1)		large_intestine(4656)|breast(2429)|upper_aerodigestive_tract(2212)|lung(2028)|ovary(1592)|oesophagus(1462)|haematopoietic_and_lymphoid_tissue(1228)|stomach(1136)|urinary_tract(1114)|central_nervous_system(1085)|liver(805)|skin(694)|pancreas(375)|biliary_tract(247)|soft_tissue(209)|prostate(194)|endometrium(150)|bone(102)|vulva(79)|kidney(79)|cervix(68)|thyroid(54)|salivary_gland(43)|adrenal_gland(37)|peritoneum(33)|eye(24)|thymus(21)|genital_tract(16)|autonomic_ganglia(16)|small_intestine(14)|testis(11)|penis(10)|vagina(6)|meninges(5)|pituitary(4)|pleura(3)|gastrointestinal_tract_(site_indeterminate)(1)|NS(1)|Fallopian tube(1)|placenta(1)	22245		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)		GBM - Glioblastoma multiforme(2;1.59e-06)|READ - Rectum adenocarcinoma(115;0.174)		GGTCTTGGCCAGTTGGCAAAA	0.562		111	Mis|N|F		breast|colorectal|lung|sarcoma|adrenocortical|glioma|multiple other tumour types	breast|sarcoma|adrenocortical carcinoma|glioma|multiple other tumour types		Other_conserved_DNA_damage_response_genes	Hereditary_Adrenocortical_Cancer|Endometrial_Cancer_Familial_Clustering_of|Hereditary_Breast-Ovarian_Cancer_non-BRCA1/2|Li-Fraumeni_syndrome|Osteosarcoma_Familial_Clustering_of	HNSCC(1;<9.43e-08)|TCGA GBM(1;<1E-08)|TSP Lung(2;<1E-08)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)			28	21					0	0	0	0
DHX58	79132	broad.mit.edu	37	17	40256842	40256842	+	Missense_Mutation	SNP	A	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr17:40256842A>C	uc002hyw.3	-	11	1728	c.1505T>G	c.(1504-1506)CTG>CGG	p.L502R	DHX58_uc002hyv.3_RNA|DHX58_uc010wgf.1_Missense_Mutation_p.L495R	NM_024119	NP_077024	Q96C10	DHX58_HUMAN	RNA helicase LGP2	502	Potential.|Helicase C-terminal.				innate immune response	cytoplasm	ATP binding|DNA binding|helicase activity|protein binding|RNA binding|zinc ion binding				0		all_cancers(22;9.73e-07)|all_epithelial(22;3.58e-05)|Breast(137;0.000143)		BRCA - Breast invasive adenocarcinoma(366;0.126)		CTGCTCCATCAGCGTCTCCAG	0.632													7	17					0	0	0	0
BRCA1	672	broad.mit.edu	37	17	41256883	41256883	+	Splice_Site	SNP	A	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr17:41256883A>C	uc002icq.2	-	5	533	c.301_splice	c.e5+1	p.Y101_splice	BRCA1_uc010whp.1_Splice_Site_p.Y54_splice|BRCA1_uc010whl.1_Splice_Site_p.Y101_splice|BRCA1_uc010whm.1_Intron|BRCA1_uc002icp.3_Splice_Site_p.Y31_splice|BRCA1_uc002icu.2_Splice_Site_p.Y101_splice|BRCA1_uc010cyx.2_Splice_Site_p.Y54_splice|BRCA1_uc002ict.2_Splice_Site_p.Y101_splice|BRCA1_uc010whn.1_Intron|BRCA1_uc010who.1_Intron|BRCA1_uc010whq.1_Intron|BRCA1_uc002idc.1_Splice_Site_p.Y101_splice|BRCA1_uc010whr.1_Splice_Site_p.Y54_splice|BRCA1_uc002idd.2_Splice_Site_p.Y101_splice|BRCA1_uc002ide.1_Intron|BRCA1_uc010cyy.1_Splice_Site_p.Y101_splice|BRCA1_uc010whs.1_Splice_Site_p.Y101_splice|BRCA1_uc010cyz.2_Splice_Site_p.Y54_splice|BRCA1_uc010cza.2_Splice_Site_p.Y75_splice|BRCA1_uc010wht.1_Intron	NM_007294	NP_009225	P38398	BRCA1_HUMAN	breast cancer 1, early onset isoform 1						androgen receptor signaling pathway|apoptosis|cellular response to indole-3-methanol|chromosome segregation|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|DNA damage response, signal transduction resulting in induction of apoptosis|double-strand break repair via homologous recombination|fatty acid biosynthetic process|G2/M transition DNA damage checkpoint|negative regulation of centriole replication|negative regulation of fatty acid biosynthetic process|negative regulation of histone H3-K9 methylation|negative regulation of transcription, DNA-dependent|positive regulation of cell cycle arrest|positive regulation of DNA repair|positive regulation of histone acetylation|positive regulation of histone H3-K4 methylation|positive regulation of histone H4-K20 methylation|positive regulation of protein ubiquitination|positive regulation of transcription from RNA polymerase II promoter|postreplication repair|protein autoubiquitination|protein K6-linked ubiquitination|regulation of cell motility|regulation of cell proliferation|regulation of transcription from RNA polymerase III promoter|response to estrogen stimulus|response to ionizing radiation|substrate adhesion-dependent cell spreading	BRCA1-A complex|BRCA1-BARD1 complex|gamma-tubulin ring complex|nucleoplasm|plasma membrane|ribonucleoprotein complex|ruffle	androgen receptor binding|identical protein binding|protein binding|RNA binding|transcription coactivator activity|transcription regulatory region DNA binding|tubulin binding|ubiquitin protein ligase binding|ubiquitin-protein ligase activity|zinc ion binding			ovary(24)|breast(21)|lung(4)|central_nervous_system(1)|endometrium(1)|urinary_tract(1)	52		Breast(137;0.000717)		BRCA - Breast invasive adenocarcinoma(366;0.126)		TTCAACACTTACACTCCAAAC	0.373			D|Mis|N|F|S		ovarian	breast|ovarian		Homologous_recombination	Hereditary_Breast-Ovarian_Cancer_BRCA1_type	TCGA Ovarian(2;0.000030)			28	47					0	0	0	0
UBTF	7343	broad.mit.edu	37	17	42284865	42284865	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr17:42284865G>A	uc002igb.2	-	19	2193	c.2126C>T	c.(2125-2127)TCC>TTC	p.S709F	UBTF_uc002igc.2_Missense_Mutation_p.S672F|UBTF_uc010czs.2_Missense_Mutation_p.S709F|UBTF_uc002igd.2_Missense_Mutation_p.S672F|UBTF_uc010czt.2_Missense_Mutation_p.S709F	NM_014233	NP_055048	P17480	UBF1_HUMAN	upstream binding transcription factor, RNA	709	Asp/Glu/Ser-rich (acidic).				positive regulation of transcription from RNA polymerase I promoter|termination of RNA polymerase I transcription|transcription elongation from RNA polymerase I promoter|transcription initiation from RNA polymerase I promoter	nucleolus|nucleoplasm	DNA binding|protein binding				0		Breast(137;0.00765)|Prostate(33;0.0181)		BRCA - Breast invasive adenocarcinoma(366;0.114)		GGACTCAGAGGAGTCGCCGCC	0.468													17	27					0	0	0	0
ITGB3	3690	broad.mit.edu	37	17	45360736	45360736	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr17:45360736C>T	uc002ilj.2	+	3	202	c.182C>T	c.(181-183)TCA>TTA	p.S61L	ITGB3_uc002ili.1_Missense_Mutation_p.S61L|ITGB3_uc010wkr.1_RNA	NM_000212	NP_000203	P05106	ITB3_HUMAN	integrin beta chain, beta 3 precursor	61	Extracellular (Potential).				activation of protein kinase activity|angiogenesis involved in wound healing|axon guidance|cell-matrix adhesion|integrin-mediated signaling pathway|interspecies interaction between organisms|leukocyte migration|negative regulation of lipid storage|negative regulation of lipid transport|negative regulation of lipoprotein metabolic process|negative regulation of low-density lipoprotein particle receptor biosynthetic process|negative regulation of macrophage derived foam cell differentiation|platelet activation|platelet degranulation|positive regulation of endothelial cell migration|positive regulation of endothelial cell proliferation|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of vascular endothelial growth factor receptor signaling pathway|regulation of bone resorption|smooth muscle cell migration|tube development	alphav-beta3 integrin-vitronectin complex|integrin complex|platelet alpha granule membrane	cell adhesion molecule binding|identical protein binding|platelet-derived growth factor receptor binding|receptor activity|vascular endothelial growth factor receptor 2 binding			central_nervous_system(5)|large_intestine(1)	6					Abciximab(DB00054)|Tirofiban(DB00775)	CCTCTGGGCTCACCTCGCTGT	0.567													21	38					0	0	0	0
IGF2BP1	10642	broad.mit.edu	37	17	47076479	47076479	+	Missense_Mutation	SNP	G	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr17:47076479G>C	uc002iom.2	+	2	518	c.184G>C	c.(184-186)GAA>CAA	p.E62Q	IGF2BP1_uc010dbj.2_Missense_Mutation_p.E62Q	NM_006546	NP_006537	Q9NZI8	IF2B1_HUMAN	insulin-like growth factor 2 mRNA binding	62	RRM 1.				CRD-mediated mRNA stabilization|negative regulation of translation|regulation of mRNA stability involved in response to stress	CRD-mediated mRNA stability complex|cytosol|dendritic spine|lamellipodium|nucleus|plasma membrane|stress granule	mRNA 3'-UTR binding|mRNA 5'-UTR binding|nucleotide binding|protein binding|translation regulator activity			kidney(1)	1						AGGGAAAGTAGAATTACAAGG	0.468													6	28					0	0	0	0
MKS1	54903	broad.mit.edu	37	17	56291137	56291137	+	Silent	SNP	T	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr17:56291137T>C	uc002ivr.1	-	7	813	c.738A>G	c.(736-738)AAA>AAG	p.K246K	MKS1_uc010wnq.1_Silent_p.K43K|MKS1_uc002ivs.1_Silent_p.K246K	NM_017777	NP_060247	Q9NXB0	MKS1_HUMAN	Meckel syndrome type 1 protein isoform 1	246					cilium assembly	centrosome|cilium|microtubule basal body	protein binding			ovary(1)	1						TGTAGGGTCCTTTGAGGCCCG	0.473													32	65					0	0	0	0
TTYH2	94015	broad.mit.edu	37	17	72246094	72246094	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr17:72246094G>A	uc002jkc.2	+	9	981	c.950G>A	c.(949-951)CGC>CAC	p.R317H	TTYH2_uc010wqw.1_Missense_Mutation_p.R296H|TTYH2_uc002jkd.2_5'UTR	NM_032646	NP_116035	Q9BSA4	TTYH2_HUMAN	tweety 2 isoform 1	317	Extracellular (Potential).					chloride channel complex|plasma membrane	chloride channel activity|protein binding			ovary(3)|large_intestine(1)	4						ACCTTCCAGCGCGCACTTACC	0.642													21	83					0	0	0	0
CETN1	1068	broad.mit.edu	37	18	580762	580762	+	Silent	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr18:580762C>T	uc002kko.1	+	1	396	c.354C>T	c.(352-354)ACC>ACT	p.T118T		NM_004066	NP_004057	Q12798	CETN1_HUMAN	centrin 1	118	EF-hand 3.				cell division|mitosis	spindle pole	ATP binding|ATP-dependent helicase activity|calcium ion binding|nucleic acid binding			upper_aerodigestive_tract(1)|ovary(1)	2						ACGATGAGACCGGGAAGATCT	0.537													23	39					0	0	0	0
C18orf1	753	broad.mit.edu	37	18	13621135	13621135	+	Missense_Mutation	SNP	A	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr18:13621135A>C	uc002ksa.2	+	5	869	c.201A>C	c.(199-201)CAA>CAC	p.Q67H	C18orf1_uc002ksb.2_Missense_Mutation_p.Q67H|C18orf1_uc002kse.2_Missense_Mutation_p.Q30H|C18orf1_uc002ksf.2_Missense_Mutation_p.Q30H|C18orf1_uc002ksg.1_5'UTR|C18orf1_uc002ksh.1_Missense_Mutation_p.Q9H|C18orf1_uc002ksi.1_Missense_Mutation_p.Q9H	NM_181481	NP_852146	O15165	CR001_HUMAN	hypothetical protein LOC753 isoform alpha 1	67	Helical; (Potential).					integral to membrane|plasma membrane				ovary(2)|skin(1)	3				READ - Rectum adenocarcinoma(73;0.0642)		AGTTCGCCCAAATCATCATCA	0.602													47	95					0	0	0	0
ZNF556	80032	broad.mit.edu	37	19	2877900	2877900	+	Missense_Mutation	SNP	A	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr19:2877900A>G	uc002lwp.1	+	4	1031	c.944A>G	c.(943-945)TAT>TGT	p.Y315C	ZNF556_uc002lwq.2_Missense_Mutation_p.Y314C	NM_024967	NP_079243	Q9HAH1	ZN556_HUMAN	zinc finger protein 556	315	C2H2-type 7.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			skin(3)	3				UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		GAGAAACCCTATAAGTGTGGA	0.527													6	36					0	0	0	0
TLE2	7089	broad.mit.edu	37	19	3002388	3002388	+	Missense_Mutation	SNP	G	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr19:3002388G>C	uc002lww.2	-	18	2273	c.2010C>G	c.(2008-2010)CAC>CAG	p.H670Q	TLE2_uc010xhb.1_Missense_Mutation_p.H337Q|TLE2_uc010dth.2_Missense_Mutation_p.H671Q|TLE2_uc010xhc.1_Missense_Mutation_p.H548Q|TLE2_uc010dti.2_Missense_Mutation_p.H684Q	NM_003260	NP_003251	Q04725	TLE2_HUMAN	transducin-like enhancer protein 2 isoform 1	670	WD 5.				negative regulation of canonical Wnt receptor signaling pathway|negative regulation of transcription, DNA-dependent|organ morphogenesis|transcription, DNA-dependent|Wnt receptor signaling pathway	nucleus	protein binding|transcription corepressor activity				0				UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		CGCAGCTCTCGTGGAGGTGCA	0.612													7	27					0	0	0	0
C3	718	broad.mit.edu	37	19	6697422	6697422	+	Missense_Mutation	SNP	A	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr19:6697422A>G	uc002mfm.2	-	21	2791	c.2729T>C	c.(2728-2730)GTG>GCG	p.V910A		NM_000064	NP_000055	P01024	CO3_HUMAN	complement component 3 precursor	910					complement activation, alternative pathway|complement activation, classical pathway|G-protein coupled receptor protein signaling pathway|inflammatory response|positive regulation vascular endothelial growth factor production	extracellular space	endopeptidase inhibitor activity|receptor binding			skin(3)|ovary(1)|pancreas(1)	5				GBM - Glioblastoma multiforme(1328;1.36e-05)|Lung(535;0.00661)		CTTGACTTCCACTTCCTGCAG	0.567													29	57					0	0	0	0
ADAMTS10	81794	broad.mit.edu	37	19	8662012	8662012	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr19:8662012G>A	uc002mkj.1	-	8	1173	c.899C>T	c.(898-900)ACT>ATT	p.T300I	ADAMTS10_uc002mkk.1_5'UTR	NM_030957	NP_112219	Q9H324	ATS10_HUMAN	ADAM metallopeptidase with thrombospondin type 1	300	Peptidase M12B.				proteolysis	proteinaceous extracellular matrix	metalloendopeptidase activity|zinc ion binding			pancreas(2)|skin(2)	4						GATCTCCAGAGTGGGCTGGGG	0.602													26	65					0	0	0	0
CHERP	10523	broad.mit.edu	37	19	16638963	16638963	+	Silent	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr19:16638963G>A	uc002nei.1	-	9	1307	c.1233C>T	c.(1231-1233)CAC>CAT	p.H411H	MED26_uc002nee.2_Intron|CHERP_uc010xpg.1_5'Flank	NM_006387	NP_006378	Q8IWX8	CHERP_HUMAN	calcium homeostasis endoplasmic reticulum	411	Pro-rich.				cellular calcium ion homeostasis|negative regulation of cell proliferation|nervous system development|RNA processing	endoplasmic reticulum|perinuclear region of cytoplasm	RNA binding			ovary(2)	2						GGATCTGGTCGTGTggcccgg	0.532													27	71					0	0	0	0
ZNF567	163081	broad.mit.edu	37	19	37210259	37210259	+	Silent	SNP	A	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr19:37210259A>G	uc010xtl.1	+	6	855	c.633A>G	c.(631-633)GGA>GGG	p.G211G	ZNF567_uc002oeo.1_Silent_p.G211G|ZNF567_uc010xtk.1_Silent_p.G211G|ZNF567_uc002oep.3_Silent_p.G180G|ZNF567_uc002oeq.1_Silent_p.G180G	NM_152603	NP_689816	Q8N184	ZN567_HUMAN	zinc finger protein 567	211	C2H2-type 1; degenerate.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0	Esophageal squamous(110;0.198)		COAD - Colon adenocarcinoma(19;0.0454)|Colorectal(19;0.065)			AGTCATTTGGATATAATGACT	0.368													16	29					0	0	0	0
LRFN1	57622	broad.mit.edu	37	19	39804929	39804929	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr19:39804929G>A	uc002okw.2	-	1	1048	c.1048C>T	c.(1048-1050)CGG>TGG	p.R350W		NM_020862	NP_065913	Q9P244	LRFN1_HUMAN	leucine rich repeat and fibronectin type III	350	Ig-like.|Extracellular (Potential).					cell junction|integral to membrane|postsynaptic density|postsynaptic membrane				ovary(2)	2	all_cancers(60;1.85e-07)|all_lung(34;4.03e-08)|Lung NSC(34;4.66e-08)|all_epithelial(25;6.4e-07)|Ovarian(47;0.0512)		Epithelial(26;1.96e-27)|all cancers(26;2.05e-24)|Lung(45;0.000278)|LUSC - Lung squamous cell carcinoma(53;0.000335)			CCGTCCCCCCGGACCCGGGTC	0.692													9	13					0	0	0	0
ZNF546	339327	broad.mit.edu	37	19	40520758	40520758	+	Silent	SNP	T	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr19:40520758T>C	uc002oms.2	+	7	1837	c.1581T>C	c.(1579-1581)TGT>TGC	p.C527C	ZNF546_uc002omt.2_Silent_p.C501C	NM_178544	NP_848639	Q86UE3	ZN546_HUMAN	zinc finger protein 546	527	C2H2-type 12.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			ovary(1)|breast(1)|skin(1)	3	all_cancers(60;9.55e-06)|all_lung(34;1.17e-07)|Lung NSC(34;1.41e-07)|Ovarian(47;0.0925)					CCTACATATGTAACGAATGTG	0.403													23	41					0	0	0	0
ZNF816A	125893	broad.mit.edu	37	19	53454451	53454451	+	Missense_Mutation	SNP	G	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr19:53454451G>C	uc002qal.1	-	5	878	c.577C>G	c.(577-579)CAA>GAA	p.Q193E	ZNF321_uc010eqj.2_Intron|ZNF321_uc002qak.1_Intron|ZNF816A_uc002qam.1_Missense_Mutation_p.Q177E	NM_001031665	NP_001026835	Q0VGE8	ZN816_HUMAN	zinc finger protein 816A	193					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0				GBM - Glioblastoma multiforme(134;0.0313)		GAAATTCTTTGGGATTCTGAA	0.378													31	64					0	0	0	0
MBOAT7	79143	broad.mit.edu	37	19	54692110	54692110	+	Missense_Mutation	SNP	G	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr19:54692110G>T	uc002qdq.2	-	4	433	c.167C>A	c.(166-168)ACC>AAC	p.T56N	MBOAT7_uc010erg.2_5'Flank|MBOAT7_uc010yem.1_Missense_Mutation_p.T38N|MBOAT7_uc002qdr.2_Missense_Mutation_p.T56N|MBOAT7_uc002qds.2_Missense_Mutation_p.H25Q|MBOAT7_uc010yen.1_Missense_Mutation_p.H25Q|MBOAT7_uc002qdt.3_Missense_Mutation_p.T56N|TSEN34_uc010yeo.1_5'Flank|TSEN34_uc002qdu.2_5'Flank|TSEN34_uc002qdv.2_5'Flank|TSEN34_uc002qdw.2_5'Flank	NM_024298	NP_077274	Q96N66	MBOA7_HUMAN	membrane bound O-acyltransferase domain	56	Helical; (Potential).				phospholipid biosynthetic process	integral to membrane	acyltransferase activity				0	all_cancers(19;0.0065)|all_epithelial(19;0.00348)|all_lung(19;0.0175)|Lung NSC(19;0.0325)|Ovarian(34;0.19)					CCCGAGGATGGTGACCAGAGA	0.642													21	37					8.04996e-18	4.54433e-17	1	0
CTNNA2	1496	broad.mit.edu	37	2	80782950	80782950	+	Missense_Mutation	SNP	T	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr2:80782950T>C	uc010ysh.1	+	11	1678	c.1673T>C	c.(1672-1674)ATG>ACG	p.M558T	CTNNA2_uc010yse.1_Missense_Mutation_p.M558T|CTNNA2_uc010ysf.1_Missense_Mutation_p.M558T|CTNNA2_uc010ysg.1_Missense_Mutation_p.M558T|CTNNA2_uc010ysi.1_Missense_Mutation_p.M190T	NM_004389	NP_004380	P26232	CTNA2_HUMAN	catenin, alpha 2 isoform 1	558					axonogenesis|brain morphogenesis|cell-cell adhesion|dendrite morphogenesis|muscle cell differentiation|positive regulation of muscle cell differentiation|prepulse inhibition|radial glia guided migration of Purkinje cell|regulation of synapse structural plasticity	actin cytoskeleton|axon|cytosol	cadherin binding|structural constituent of cytoskeleton			pancreas(4)|lung(3)|breast(1)|skin(1)	9						AATGCTGAGATGGAGAACTAT	0.512													10	79					0	0	0	0
GCG	2641	broad.mit.edu	37	2	163005678	163005678	+	Missense_Mutation	SNP	A	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr2:163005678A>G	uc002ucc.2	-	2	110	c.11T>C	c.(10-12)ATT>ACT	p.I4T		NM_002054	NP_002045	P01275	GLUC_HUMAN	glucagon preproprotein	4					cell proliferation|cellular response to glucagon stimulus|energy reserve metabolic process|feeding behavior|regulation of insulin secretion	plasma membrane|soluble fraction	hormone activity				0					Exenatide(DB01276)|Phentolamine(DB00692)	CACAAAGTAAATGCTTTTCAT	0.433													59	114					0	0	0	0
LRP2	4036	broad.mit.edu	37	2	170134277	170134277	+	Missense_Mutation	SNP	C	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr2:170134277C>A	uc002ues.2	-	13	1963	c.1750G>T	c.(1750-1752)GTA>TTA	p.V584L	LRP2_uc010zdf.1_Intron	NM_004525	NP_004516	P98164	LRP2_HUMAN	low density lipoprotein-related protein 2	584	LDL-receptor class B 4.|Extracellular (Potential).				hormone biosynthetic process|protein glycosylation|receptor-mediated endocytosis|vitamin D metabolic process	coated pit|integral to membrane|lysosome	calcium ion binding|receptor activity|SH3 domain binding			ovary(13)|skin(6)|central_nervous_system(4)|large_intestine(3)|kidney(2)|pancreas(1)	29				STAD - Stomach adenocarcinoma(1183;0.000766)|COAD - Colon adenocarcinoma(177;0.0101)	Gentamicin(DB00798)|Insulin Glargine recombinant(DB00047)|Insulin Lyspro recombinant(DB00046)|Insulin recombinant(DB00030)|Insulin, porcine(DB00071)|Urokinase(DB00013)	TCATAAGTTACAGTTTCAATG	0.388													25	43					4.26978e-12	2.35342e-11	1	0
ARPC2	10109	broad.mit.edu	37	2	219099116	219099116	+	Silent	SNP	A	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr2:219099116A>G	uc002vhd.2	+	5	376	c.264A>G	c.(262-264)GAA>GAG	p.E88E	ARPC2_uc002vhe.2_Silent_p.E88E|ARPC2_uc002vhf.2_5'Flank	NM_152862	NP_690601	O15144	ARPC2_HUMAN	actin related protein 2/3 complex subunit 2	88					cellular component movement	Arp2/3 protein complex|cell projection|Golgi apparatus	actin binding|structural constituent of cytoskeleton			ovary(1)	1		Renal(207;0.0474)		Epithelial(149;1.21e-06)|all cancers(144;0.000212)|LUSC - Lung squamous cell carcinoma(224;0.00829)|Lung(261;0.0103)		TAAATCCAGAATCAGGTATGT	0.328													19	45					0	0	0	0
ACSL3	2181	broad.mit.edu	37	2	223773571	223773571	+	Missense_Mutation	SNP	T	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr2:223773571T>A	uc002vni.2	+	4	532	c.81T>A	c.(79-81)CAT>CAA	p.H27Q	ACSL3_uc002vnj.2_Missense_Mutation_p.H27Q	NM_004457	NP_004448	O95573	ACSL3_HUMAN	acyl-CoA synthetase long-chain family member 3	27	Helical; Signal-anchor for type III membrane protein; (Potential).				long-chain fatty-acyl-CoA biosynthetic process|triglyceride biosynthetic process	endoplasmic reticulum membrane|integral to membrane|microsome|mitochondrial outer membrane|peroxisomal membrane	ATP binding|fatty-acyl-CoA synthase activity|long-chain fatty acid-CoA ligase activity|protein binding			ovary(2)	2		Renal(207;0.0183)		Epithelial(121;1.28e-10)|all cancers(144;8.06e-08)|Lung(261;0.00834)|LUSC - Lung squamous cell carcinoma(224;0.00864)	Icosapent(DB00159)	ATTTTATACATTTTCTAATAT	0.289			T	ETV1	prostate								19	39					0	0	0	0
DGKD	8527	broad.mit.edu	37	2	234346041	234346041	+	Nonsense_Mutation	SNP	G	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr2:234346041G>T	uc002vui.1	+	8	850	c.838G>T	c.(838-840)GAA>TAA	p.E280*	DGKD_uc002vuj.1_Nonsense_Mutation_p.E236*|DGKD_uc010fyh.1_Nonsense_Mutation_p.E147*|DGKD_uc010fyi.1_5'Flank|DGKD_uc002vuk.1_Nonsense_Mutation_p.E147*	NM_152879	NP_690618	Q16760	DGKD_HUMAN	diacylglycerol kinase, delta 130kDa isoform 2	280	Phorbol-ester/DAG-type 2.				activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway|cell growth|diacylglycerol metabolic process|endocytosis|epidermal growth factor receptor signaling pathway|multicellular organismal development|platelet activation|protein homooligomerization|protein transport|response to organic substance|second-messenger-mediated signaling	cytoplasm|cytoplasmic membrane-bounded vesicle|plasma membrane|plasma membrane	ATP binding|diacylglycerol binding|diacylglycerol kinase activity|metal ion binding|protein heterodimerization activity|protein homodimerization activity			central_nervous_system(2)|pancreas(1)|lung(1)|skin(1)	5		Breast(86;0.0013)|Renal(207;0.00339)|all_hematologic(139;0.0116)|all_lung(227;0.0179)|Acute lymphoblastic leukemia(138;0.0326)|Lung NSC(271;0.0538)		Epithelial(121;1.31e-16)|BRCA - Breast invasive adenocarcinoma(100;0.000416)|Lung(119;0.00285)|LUSC - Lung squamous cell carcinoma(224;0.00655)	Phosphatidylserine(DB00144)	ATCGTGTAAAGAATCCTTGCT	0.542													11	22					0.000978159	0.00478819	1	0
LRRFIP1	9208	broad.mit.edu	37	2	238672160	238672160	+	Missense_Mutation	SNP	T	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr2:238672160T>G	uc002vxe.2	+	11	2096	c.1804T>G	c.(1804-1806)TTA>GTA	p.L602V	LRRFIP1_uc002vxc.2_Intron|LRRFIP1_uc010znm.1_Intron|LRRFIP1_uc002vxd.2_Missense_Mutation_p.L578V|LRRFIP1_uc002vxf.2_Missense_Mutation_p.L546V	NM_001137552	NP_001131024	Q32MZ4	LRRF1_HUMAN	leucine rich repeat (in FLII) interacting	602					negative regulation of transcription, DNA-dependent|regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	cytoplasm|cytoskeleton|nucleus	DNA binding|double-stranded RNA binding|protein binding			breast(3)	3		Breast(86;0.00257)|Renal(207;0.00571)|Ovarian(221;0.17)|all_hematologic(139;0.182)		Epithelial(121;9.75e-23)|OV - Ovarian serous cystadenocarcinoma(60;1.01e-10)|Kidney(56;4.85e-09)|KIRC - Kidney renal clear cell carcinoma(57;1.31e-07)|BRCA - Breast invasive adenocarcinoma(100;0.000151)|Lung(119;0.0137)|LUSC - Lung squamous cell carcinoma(224;0.0325)|COAD - Colon adenocarcinoma(134;0.228)		GAACACAGATTTAAGTGAAAT	0.318													5	11					0	0	0	0
FAM182B	728882	broad.mit.edu	37	20	25848629	25848629	+	RNA	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr20:25848629C>T	uc002wvd.1	-	1		c.158G>A								Homo sapiens cDNA FLJ30282 fis, clone BRACE2002803.												0						gctgggatgccgtgctgcttc	0													3	10					0	0	0	0
CDH26	60437	broad.mit.edu	37	20	58560126	58560126	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr20:58560126C>T	uc002ybe.2	+	7	1079	c.779C>T	c.(778-780)ACC>ATC	p.T260I	CDH26_uc010zzy.1_RNA	NM_177980	NP_817089	Q8IXH8	CAD26_HUMAN	cadherin-like 26 isoform a	260	Cadherin 2.|Extracellular (Potential).				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			ovary(3)|central_nervous_system(1)	4	all_lung(29;0.00963)		BRCA - Breast invasive adenocarcinoma(7;5.58e-09)			TCCACGACCACCGTTCACGTG	0.547													8	42					0	0	0	0
BAGE2	85319	broad.mit.edu	37	21	11049596	11049596	+	Missense_Mutation	SNP	C	T	T	rs28571918		TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr21:11049596C>T	uc002yit.1	-	4	513	c.305G>A	c.(304-306)TGT>TAT	p.C102Y		NM_182482	NP_872288			B melanoma antigen family, member 2 precursor												0			Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		GGCTGTCGCACACTGCACAGT	0.373													27	110					0	0	0	0
KRTAP13-1	140258	broad.mit.edu	37	21	31768590	31768590	+	Missense_Mutation	SNP	G	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr21:31768590G>T	uc002yoa.2	+	1	199	c.186G>T	c.(184-186)GAG>GAT	p.E62D		NM_181599	NP_853630	Q8IUC0	KR131_HUMAN	keratin associated protein 13-1	62	5 X 10 AA approximate repeats.|2.					intermediate filament		p.E62D(1)		ovary(1)	1						CCTGCTGGGAGCCCACCAGCT	0.612													19	43					1.33834e-09	7.09724e-09	1	0
PRDM15	63977	broad.mit.edu	37	21	43279700	43279700	+	Splice_Site	SNP	C	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr21:43279700C>A	uc002yzq.1	-	9	1142	c.1031_splice	c.e9+1	p.R344_splice	PRDM15_uc002yzo.2_Splice_Site_p.R81_splice|PRDM15_uc002yzp.2_Splice_Site_p.R81_splice|PRDM15_uc002yzr.1_Splice_Site_p.R81_splice	NM_022115	NP_071398	P57071	PRD15_HUMAN	PR domain containing 15 isoform 1						regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding				0						CGGTCACTCACCTTGCCCTGC	0.612													10	12					3.86212e-05	0.000194495	1	0
TFIP11	24144	broad.mit.edu	37	22	26902303	26902303	+	Silent	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr22:26902303G>A	uc003acr.2	-	5	860	c.486C>T	c.(484-486)TAC>TAT	p.Y162Y	TFIP11_uc003acs.2_Silent_p.Y162Y|TFIP11_uc003act.2_Silent_p.Y162Y	NM_012143	NP_036275	Q9UBB9	TFP11_HUMAN	tuftelin interacting protein 11	162	G-patch.				biomineral tissue development	catalytic step 2 spliceosome|cytoplasm|nuclear speck	DNA binding|sequence-specific DNA binding transcription factor activity				0						GTCCAGGGACGTAGCCCATCT	0.527													14	86					0	0	0	0
FBLN1	2192	broad.mit.edu	37	22	45944530	45944530	+	Missense_Mutation	SNP	C	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr22:45944530C>G	uc003bgj.1	+	13	1626	c.1479C>G	c.(1477-1479)ATC>ATG	p.I493M	FBLN1_uc003bgg.1_Missense_Mutation_p.I493M|FBLN1_uc003bgh.2_Missense_Mutation_p.I493M|FBLN1_uc010gzz.2_Missense_Mutation_p.I531M|FBLN1_uc003bgi.1_Missense_Mutation_p.I493M	NM_006486	NP_006477	P23142	FBLN1_HUMAN	fibulin 1 isoform D	493	EGF-like 8; calcium-binding.				interspecies interaction between organisms	extracellular space|soluble fraction	calcium ion binding|extracellular matrix structural constituent|protein binding			ovary(1)|central_nervous_system(1)	2		Ovarian(80;0.00965)|all_neural(38;0.0416)		UCEC - Uterine corpus endometrioid carcinoma (28;0.0182)		GGGGCCACATCTGCTCCTACC	0.652													13	38					0	0	0	0
CCR8	1237	broad.mit.edu	37	3	39374725	39374725	+	Silent	SNP	T	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr3:39374725T>G	uc010hhr.2	+	2	1041	c.903T>G	c.(901-903)GCT>GCG	p.A301A	CCR8_uc003cjm.2_Silent_p.A218A	NM_005201	NP_005192	P51685	CCR8_HUMAN	chemokine (C-C motif) receptor 8	301	Helical; Name=7; (Potential).				cell adhesion|chemotaxis|elevation of cytosolic calcium ion concentration|immune response	integral to plasma membrane	coreceptor activity			ovary(1)|lung(1)	2				KIRC - Kidney renal clear cell carcinoma(284;0.0504)|Kidney(284;0.0635)		TTATCTATGCTTTTGTTGGGG	0.423													20	27					0	0	0	0
RBM6	10180	broad.mit.edu	37	3	50095370	50095370	+	Missense_Mutation	SNP	A	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr3:50095370A>T	uc003cyc.2	+	9	2036	c.1903A>T	c.(1903-1905)ACT>TCT	p.T635S	RBM6_uc011bdh.1_RNA|RBM6_uc010hlc.1_Missense_Mutation_p.T154S|RBM6_uc003cyd.2_Missense_Mutation_p.T113S|RBM6_uc003cye.2_Missense_Mutation_p.T113S|RBM6_uc011bdi.1_5'UTR|RBM6_uc010hld.1_RNA|RBM6_uc010hle.1_RNA|RBM6_uc010hlf.1_RNA	NM_005777	NP_005768	P78332	RBM6_HUMAN	RNA binding motif protein 6	635					RNA processing	nucleus	DNA binding|nucleotide binding|RNA binding|zinc ion binding			ovary(2)	2				BRCA - Breast invasive adenocarcinoma(193;6.81e-05)|KIRC - Kidney renal clear cell carcinoma(197;0.0084)|Kidney(197;0.00977)		GGAAGGGCCAACTTTCCGAAG	0.517													6	10					0	0	0	0
FOXP1	27086	broad.mit.edu	37	3	71026794	71026794	+	Missense_Mutation	SNP	C	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr3:71026794C>G	uc003dol.2	-	12	1751	c.1428G>C	c.(1426-1428)CAG>CAC	p.Q476H	FOXP1_uc003dom.2_Missense_Mutation_p.Q400H|FOXP1_uc003don.2_RNA|FOXP1_uc003doo.2_Missense_Mutation_p.Q475H|FOXP1_uc003dop.2_Missense_Mutation_p.Q476H|FOXP1_uc003doq.1_Missense_Mutation_p.Q475H|FOXP1_uc003doi.2_Missense_Mutation_p.Q376H|FOXP1_uc003doj.2_Missense_Mutation_p.Q376H|FOXP1_uc003dok.2_Missense_Mutation_p.Q289H|FOXP1_uc003dor.1_Missense_Mutation_p.Q253H	NM_032682	NP_116071	Q9H334	FOXP1_HUMAN	forkhead box P1 isoform 1	476	Fork-head.				cardiac muscle cell differentiation|embryo development|immunoglobulin V(D)J recombination|pattern specification process|positive regulation of epithelial cell proliferation involved in lung morphogenesis|positive regulation of immunoglobulin production|positive regulation of mesenchymal cell proliferation|pre-B cell differentiation|regulation of sequence-specific DNA binding transcription factor activity|skeletal muscle tissue development|smooth muscle tissue development	cytoplasm|transcription factor complex	chromatin binding|DNA bending activity|double-stranded DNA binding|promoter binding|protein heterodimerization activity|protein homodimerization activity|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding|zinc ion binding			ovary(1)|lung(1)	2		Lung NSC(201;4.62e-05)|Prostate(10;0.0181)|Hepatocellular(537;0.186)|Myeloproliferative disorder(1037;0.209)		BRCA - Breast invasive adenocarcinoma(55;1.17e-05)|Epithelial(33;1.39e-05)|LUSC - Lung squamous cell carcinoma(21;2.35e-05)|Lung(16;4.26e-05)		ATTTACTTACCTGCCTAATTA	0.323			T	PAX5	ALL								10	48					0	0	0	0
ALG1L2	644974	broad.mit.edu	37	3	129811047	129811047	+	Missense_Mutation	SNP	A	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr3:129811047A>T	uc011bld.1	+	3	421	c.235A>T	c.(235-237)AGC>TGC	p.S79C	ALG1L2_uc010hth.2_RNA	NM_001136152	NP_001129624	C9J202	AG1L2_HUMAN	asparagine-linked glycosylation 1-like 2	79					biosynthetic process		transferase activity, transferring glycosyl groups				0						CCTGCTGGTCAGCAGCACAAG	0.642													3	9					0	0	0	0
TXNDC6	347736	broad.mit.edu	37	3	138037035	138037035	+	Silent	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr3:138037035G>A	uc003esg.2	-	4	250	c.222C>T	c.(220-222)CTC>CTT	p.L74L	TXNDC6_uc003esd.1_RNA|TXNDC6_uc010huf.1_Intron|TXNDC6_uc003ese.1_Silent_p.L52L	NM_178130	NP_835231	Q86XW9	TXND6_HUMAN	thioredoxin domain containing 6	74	Thioredoxin.				cell redox homeostasis|CTP biosynthetic process|GTP biosynthetic process|UTP biosynthetic process	cytoplasm|cytoskeleton	ATP binding|nucleoside diphosphate kinase activity			breast(3)|ovary(1)|pancreas(1)	5						TGTACTTTTCGAGGACATCAA	0.458													46	32					0	0	0	0
MUC4	4585	broad.mit.edu	37	3	195498614	195498614	+	Missense_Mutation	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr3:195498614G>A	uc011bto.1	-	6	13227	c.12767C>T	c.(12766-12768)ACA>ATA	p.T4256I	MUC4_uc003fuz.2_Nonsense_Mutation_p.Q64*|MUC4_uc003fva.2_Intron|MUC4_uc003fvb.2_Intron|MUC4_uc003fvc.2_Intron|MUC4_uc003fvd.2_RNA|MUC4_uc003fve.2_5'UTR|MUC4_uc010hzr.2_RNA|MUC4_uc011btf.1_5'UTR|MUC4_uc011btg.1_RNA|MUC4_uc011bth.1_5'UTR|MUC4_uc011bti.1_Intron|MUC4_uc011btj.1_Missense_Mutation_p.T125I|MUC4_uc011btk.1_5'UTR|MUC4_uc011btl.1_Intron|MUC4_uc011btm.1_Missense_Mutation_p.T125I|MUC4_uc011btn.1_Intron|MUC4_uc003fvo.2_Missense_Mutation_p.T148I|MUC4_uc003fvp.2_Missense_Mutation_p.T97I|MUC4_uc010hzu.1_Missense_Mutation_p.T996I	NM_018406	NP_060876	Q99102	MUC4_HUMAN	mucin 4 isoform a	1141					cell-matrix adhesion	integral to plasma membrane|proteinaceous extracellular matrix	ErbB-2 class receptor binding|extracellular matrix constituent, lubricant activity				0	all_cancers(143;1.11e-08)|Ovarian(172;0.0634)|Breast(254;0.206)	Lung NSC(153;0.191)	Epithelial(36;3.72e-24)|all cancers(36;6.22e-22)|OV - Ovarian serous cystadenocarcinoma(49;1.1e-18)|Lung(62;4.65e-05)|LUSC - Lung squamous cell carcinoma(58;5.31e-05)	GBM - Glioblastoma multiforme(46;2.37e-05)		TGTGAAGCCTGTTGGGAGTGG	0.557													30	85					0	0	0	0
KIAA0232	9778	broad.mit.edu	37	4	6864910	6864910	+	Missense_Mutation	SNP	A	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr4:6864910A>G	uc003gjr.3	+	7	3264	c.2801A>G	c.(2800-2802)TAT>TGT	p.Y934C	KIAA0232_uc003gjq.3_Missense_Mutation_p.Y934C	NM_014743	NP_055558	Q92628	K0232_HUMAN	hypothetical protein LOC9778	934							ATP binding			ovary(2)	2						GGAGGAGTTTATGGAGAACTC	0.443													10	37					0	0	0	0
AGPAT9	84803	broad.mit.edu	37	4	84519214	84519214	+	Missense_Mutation	SNP	A	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr4:84519214A>T	uc003how.2	+	11	1225	c.1007A>T	c.(1006-1008)CAG>CTG	p.Q336L	AGPAT9_uc003hox.2_Missense_Mutation_p.Q336L|AGPAT9_uc003hoy.2_Missense_Mutation_p.Q336L	NM_032717	NP_116106	Q53EU6	GPAT3_HUMAN	1-acylglycerol-3-phosphate O-acyltransferase 9	336					phospholipid biosynthetic process|regulation of TOR signaling cascade|triglyceride biosynthetic process	endoplasmic reticulum membrane|integral to membrane	glycerol-3-phosphate O-acyltransferase activity			skin(1)	1		Hepatocellular(203;0.114)				TATAACCCTCAGTTCGGTGAT	0.433													16	53					0	0	0	0
UNC5C	8633	broad.mit.edu	37	4	96222757	96222757	+	Missense_Mutation	SNP	A	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr4:96222757A>T	uc003htp.1	-	3	644	c.490T>A	c.(490-492)TAT>AAT	p.Y164N	UNC5C_uc010ilc.1_Missense_Mutation_p.Y164N|UNC5C_uc003htq.2_Missense_Mutation_p.Y164N	NM_003728	NP_003719	O95185	UNC5C_HUMAN	unc5C precursor	164	Extracellular (Potential).|Ig-like C2-type.				apoptosis|axon guidance|brain development	integral to membrane	netrin receptor activity			ovary(3)|pancreas(1)	4		Hepatocellular(203;0.114)		OV - Ovarian serous cystadenocarcinoma(123;8.72e-10)		AATGACTCACATGCAATGCGC	0.483													13	60					0	0	0	0
C4orf31	79625	broad.mit.edu	37	4	121958534	121958534	+	Missense_Mutation	SNP	G	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr4:121958534G>T	uc003idq.1	-	4	1119	c.592C>A	c.(592-594)CCA>ACA	p.P198T		NM_024574	NP_078850	Q8TB73	CD031_HUMAN	hypothetical protein LOC79625 precursor	198											0						GTGGGGCTTGGTTTCCAGGCC	0.493													16	115					3.32936e-07	1.73922e-06	1	0
TNIP3	79931	broad.mit.edu	37	4	122063056	122063056	+	Missense_Mutation	SNP	G	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr4:122063056G>T	uc010ing.2	-	9	996	c.800C>A	c.(799-801)CCC>CAC	p.P267H	TNIP3_uc010inh.2_Missense_Mutation_p.P267H|TNIP3_uc011cgj.1_Missense_Mutation_p.P325H	NM_024873	NP_079149	Q96KP6	TNIP3_HUMAN	TNFAIP3 interacting protein 3	267										ovary(1)	1						GCAGTTACAGGGTGGGCAATA	0.507													7	40					7.48243e-07	3.85125e-06	1	0
PLK4	10733	broad.mit.edu	37	4	128814677	128814677	+	Missense_Mutation	SNP	A	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr4:128814677A>G	uc003ifo.2	+	12	2577	c.2332A>G	c.(2332-2334)ATT>GTT	p.I778V	PLK4_uc011cgs.1_Missense_Mutation_p.I746V|PLK4_uc011cgt.1_Missense_Mutation_p.I737V	NM_014264	NP_055079	O00444	PLK4_HUMAN	polo-like kinase 4	778					G2/M transition of mitotic cell cycle|positive regulation of centriole replication|trophoblast giant cell differentiation	centriole|cleavage furrow|cytosol|nucleolus	ATP binding|protein binding|protein serine/threonine kinase activity|protein tyrosine kinase activity				0						GGGTCATCGTATTTGTTTAGC	0.338													11	50					0	0	0	0
ROPN1L	83853	broad.mit.edu	37	5	10448390	10448390	+	Silent	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr5:10448390G>A	uc003jex.3	+	2	421	c.150G>A	c.(148-150)TCG>TCA	p.S50S		NM_031916	NP_114122	Q96C74	ROP1L_HUMAN	ropporin 1-like	50					ciliary or flagellar motility|signal transduction	cytoplasm|motile cilium	cAMP-dependent protein kinase regulator activity|protein binding			ovary(1)	1						CAGCTCTGTCGAGAGGAGATC	0.423													24	48					0	0	0	0
LIFR	3977	broad.mit.edu	37	5	38493875	38493875	+	Missense_Mutation	SNP	A	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr5:38493875A>G	uc010ive.1	-	14	2230	c.1898T>C	c.(1897-1899)ATA>ACA	p.I633T	LIFR_uc003jli.2_Missense_Mutation_p.I633T	NM_001127671	NP_001121143	P42702	LIFR_HUMAN	leukemia inhibitory factor receptor precursor	633	Fibronectin type-III 5.|Extracellular (Potential).				positive regulation of cell proliferation	extracellular region|integral to plasma membrane	ciliary neurotrophic factor receptor binding|growth factor binding|leukemia inhibitory factor receptor activity			ovary(3)|large_intestine(1)	4	all_lung(31;0.00021)					AACTTGTTCTATTTTGAGATC	0.383			T	PLAG1	salivary adenoma								20	34					0	0	0	0
PCDHB5	26167	broad.mit.edu	37	5	140517214	140517214	+	Missense_Mutation	SNP	G	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr5:140517214G>C	uc003liq.2	+	1	2415	c.2198G>C	c.(2197-2199)GGG>GCG	p.G733A		NM_015669	NP_056484	Q9Y5E4	PCDB5_HUMAN	protocadherin beta 5 precursor	733	Cytoplasmic (Potential).				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to membrane|plasma membrane	calcium ion binding|protein binding			skin(3)|ovary(2)	5			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			CCCTTTCCAGGGCATCTGGTG	0.652													56	79					0	0	0	0
JAKMIP2	9832	broad.mit.edu	37	5	147040903	147040903	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr5:147040903C>T	uc003loq.1	-	3	617	c.235G>A	c.(235-237)GAG>AAG	p.E79K	JAKMIP2_uc011dbx.1_Missense_Mutation_p.E37K|JAKMIP2_uc003lor.1_Missense_Mutation_p.E79K|uc003lop.1_3'UTR|JAKMIP2_uc010jgo.1_Missense_Mutation_p.E79K	NM_014790	NP_055605	Q96AA8	JKIP2_HUMAN	janus kinase and microtubule interacting protein	79	Potential.					Golgi apparatus				large_intestine(1)|ovary(1)	2			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			ATCTTCTCCTCATGGAGCTTG	0.517													64	65					0	0	0	0
C6orf10	10665	broad.mit.edu	37	6	32337718	32337718	+	Missense_Mutation	SNP	A	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr6:32337718A>C	uc011dpy.1	-	2	229	c.56T>G	c.(55-57)ATC>AGC	p.I19S	C6orf10_uc011dpz.1_Missense_Mutation_p.I19S	NM_006781	NP_006772	Q5SRN2	CF010_HUMAN	chromosome 6 open reading frame 10	19	Helical; (Potential).					integral to membrane				skin(1)	1						AATAGCCAGGATGGCAAGTCC	0.403													64	102					0	0	0	0
PHF3	23469	broad.mit.edu	37	6	64422440	64422440	+	Silent	SNP	T	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr6:64422440T>A	uc003pep.1	+	15	4982	c.4956T>A	c.(4954-4956)CCT>CCA	p.P1652P	PHF3_uc003pen.2_Silent_p.P1564P|PHF3_uc011dxs.1_Silent_p.P921P	NM_015153	NP_055968	Q92576	PHF3_HUMAN	PHD finger protein 3	1652					multicellular organismal development|transcription, DNA-dependent	nucleus	zinc ion binding			ovary(3)|lung(1)|skin(1)	5	all_cancers(3;0.0241)|all_epithelial(2;0.00306)|Lung NSC(77;0.121)		LUSC - Lung squamous cell carcinoma(74;0.0644)|Lung(124;0.148)			AAAGGGATCCTAGGCAAGCAG	0.453													10	27					0	0	0	0
SIM1	6492	broad.mit.edu	37	6	100838366	100838366	+	Missense_Mutation	SNP	G	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr6:100838366G>T	uc003pqj.3	-	11	2379	c.2172C>A	c.(2170-2172)AGC>AGA	p.S724R	SIM1_uc010kcu.2_Missense_Mutation_p.S724R	NM_005068	NP_005059	P81133	SIM1_HUMAN	single-minded homolog 1	724	Single-minded C-terminal.				cell differentiation|nervous system development	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|signal transducer activity			ovary(4)	4		all_cancers(76;9.88e-06)|Acute lymphoblastic leukemia(125;4.99e-11)|all_hematologic(75;5.82e-08)|all_epithelial(107;0.0248)|Colorectal(196;0.13)		BRCA - Breast invasive adenocarcinoma(108;0.0774)		TAATGGTTTCGCTGTCATATA	0.463													17	83					0.000566183	0.00281084	1	0
GPR126	57211	broad.mit.edu	37	6	142718817	142718817	+	Missense_Mutation	SNP	C	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr6:142718817C>G	uc010khc.2	+	10	1903	c.1492C>G	c.(1492-1494)CAG>GAG	p.Q498E	GPR126_uc010khd.2_Missense_Mutation_p.Q470E|GPR126_uc010khe.2_Missense_Mutation_p.Q498E|GPR126_uc010khf.2_Missense_Mutation_p.Q470E	NM_020455	NP_065188	Q86SQ4	GP126_HUMAN	G protein-coupled receptor 126 alpha 1	498	Extracellular (Potential).				neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			ovary(1)	1	Breast(32;0.176)			OV - Ovarian serous cystadenocarcinoma(155;9.33e-06)|GBM - Glioblastoma multiforme(68;0.00121)		AAAAATCATTCAGCAGAAGCT	0.373													5	36					0	0	0	0
SYNE1	23345	broad.mit.edu	37	6	152757214	152757214	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr6:152757214C>T	uc010kiw.2	-	33	4774	c.4172G>A	c.(4171-4173)AGT>AAT	p.S1391N	SYNE1_uc003qot.3_Missense_Mutation_p.S1398N|SYNE1_uc003qou.3_Missense_Mutation_p.S1391N|SYNE1_uc010kjb.1_Missense_Mutation_p.S1374N|SYNE1_uc003qow.2_Missense_Mutation_p.S686N|SYNE1_uc003qox.1_Missense_Mutation_p.S907N	NM_182961	NP_892006	Q8NF91	SYNE1_HUMAN	spectrin repeat containing, nuclear envelope 1	1391	Potential.|Cytoplasmic (Potential).				cell death|cytoskeletal anchoring at nuclear membrane|Golgi organization|muscle cell differentiation|nuclear matrix anchoring at nuclear membrane	cytoskeleton|Golgi apparatus|integral to membrane|nuclear outer membrane|postsynaptic membrane|sarcomere|SUN-KASH complex	actin binding|lamin binding			central_nervous_system(15)|upper_aerodigestive_tract(9)|ovary(8)|skin(6)|large_intestine(5)|pancreas(2)	45		Ovarian(120;0.0955)	BRCA - Breast invasive adenocarcinoma(37;0.243)	OV - Ovarian serous cystadenocarcinoma(155;2.24e-10)		GACTGCAATACTTTCTGTCCG	0.398										HNSCC(10;0.0054)			7	47					0	0	0	0
SYNJ2	8871	broad.mit.edu	37	6	158516842	158516842	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr6:158516842C>T	uc003qqx.1	+	27	4012	c.3937C>T	c.(3937-3939)CCT>TCT	p.P1313S	SYNJ2_uc003qqy.1_Missense_Mutation_p.P1026S|SYNJ2_uc003qqz.1_Missense_Mutation_p.P930S|SYNJ2_uc003qra.1_Missense_Mutation_p.P656S|SYNJ2_uc010kjp.1_Missense_Mutation_p.P196S	NM_003898	NP_003889	O15056	SYNJ2_HUMAN	synaptojanin 2	1313	Catalytic (By similarity).|Pro-rich.						nucleotide binding|phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity|RNA binding			skin(1)	1				OV - Ovarian serous cystadenocarcinoma(65;4.42e-18)|BRCA - Breast invasive adenocarcinoma(81;4.23e-05)		CGAAGCCCCTCCTGGGGCAGG	0.632													6	56					0	0	0	0
POM121	9883	broad.mit.edu	37	7	72413896	72413896	+	Missense_Mutation	SNP	A	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr7:72413896A>G	uc003twk.2	+	11	3364	c.3364A>G	c.(3364-3366)ACC>GCC	p.T1122A	POM121_uc003twj.2_Missense_Mutation_p.T857A|POM121_uc010lam.1_Missense_Mutation_p.T857A	NM_172020	NP_742017	Q96HA1	P121A_HUMAN	nuclear pore membrane protein 121	1122	Pore side (Potential).				carbohydrate metabolic process|glucose transport|mRNA transport|protein transport|regulation of glucose transport|transmembrane transport|viral reproduction	endoplasmic reticulum membrane|nuclear membrane|nuclear pore					0		Lung NSC(55;0.163)				AGGCTCCAGCACCACCACCGG	0.637													3	24					0	0	0	0
SEMA3E	9723	broad.mit.edu	37	7	83119474	83119474	+	Missense_Mutation	SNP	C	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr7:83119474C>G	uc003uhy.1	-	2	698	c.232G>C	c.(232-234)GTA>CTA	p.V78L		NM_012431	NP_036563	O15041	SEM3E_HUMAN	semaphorin 3E precursor	78	Sema.				axon guidance	extracellular space|membrane	receptor activity	p.V78V(1)		ovary(3)	3		Medulloblastoma(109;0.109)				AGGGAATATACAAGGTCCCTG	0.413													8	45					0	0	0	0
MUC17	140453	broad.mit.edu	37	7	100682562	100682562	+	Missense_Mutation	SNP	G	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr7:100682562G>T	uc003uxp.1	+	3	7918	c.7865G>T	c.(7864-7866)AGC>ATC	p.S2622I	MUC17_uc010lho.1_RNA	NM_001040105	NP_001035194	Q685J3	MUC17_HUMAN	mucin 17 precursor	2622	Extracellular (Potential).|59 X approximate tandem repeats.|42.|Ser-rich.					extracellular region|integral to membrane|plasma membrane	extracellular matrix constituent, lubricant activity			ovary(14)|skin(8)|breast(3)|lung(2)	27	Lung NSC(181;0.136)|all_lung(186;0.182)					AAAGATACCAGCATGCCAATC	0.453													75	310					1.79293e-35	1.05467e-34	1	0
C7orf60	154743	broad.mit.edu	37	7	112462082	112462082	+	Missense_Mutation	SNP	T	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr7:112462082T>C	uc003vgo.1	-	5	1062	c.935A>G	c.(934-936)CAT>CGT	p.H312R	C7orf60_uc011kms.1_Missense_Mutation_p.H338R	NM_152556	NP_689769	Q1RMZ1	CG060_HUMAN	hypothetical protein LOC154743	312										ovary(2)|skin(1)	3						CAGATGCATATGTGAAAATTT	0.388													10	32					0	0	0	0
RP1	6101	broad.mit.edu	37	8	55539875	55539875	+	Missense_Mutation	SNP	T	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr8:55539875T>C	uc003xsd.1	+	4	3581	c.3433T>C	c.(3433-3435)TTC>CTC	p.F1145L	RP1_uc011ldy.1_Intron	NM_006269	NP_006260	P56715	RP1_HUMAN	retinitis pigmentosa RP1 protein	1145					axoneme assembly|intracellular signal transduction|photoreceptor cell maintenance|photoreceptor cell outer segment organization|phototransduction, visible light|retinal cone cell development|retinal rod cell development	cilium axoneme|cytoplasm|microtubule|microtubule associated complex|photoreceptor connecting cilium|photoreceptor inner segment|photoreceptor outer segment	microtubule binding			skin(7)|ovary(4)|pancreas(1)	12		all_lung(136;0.0831)|Lung NSC(129;0.109)|all_epithelial(80;0.123)	OV - Ovarian serous cystadenocarcinoma(7;4.4e-07)|Epithelial(17;3.37e-05)|all cancers(17;0.000285)			TATGAATAGCTTCTGTCAAGT	0.408													4	84					0	0	0	0
KCNB2	9312	broad.mit.edu	37	8	73849904	73849904	+	Missense_Mutation	SNP	G	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr8:73849904G>C	uc003xzb.2	+	3	2902	c.2314G>C	c.(2314-2316)GAG>CAG	p.E772Q		NM_004770	NP_004761	Q92953	KCNB2_HUMAN	potassium voltage-gated channel, Shab-related	772	Cytoplasmic (Potential).				regulation of smooth muscle contraction	voltage-gated potassium channel complex	delayed rectifier potassium channel activity|protein binding			skin(3)|large_intestine(1)|pancreas(1)|ovary(1)|central_nervous_system(1)	7	Breast(64;0.137)		Epithelial(68;0.105)			GCTGGGCACTGAGGTTTCAGC	0.552													23	113					0	0	0	0
TRHR	7201	broad.mit.edu	37	8	110131311	110131311	+	Missense_Mutation	SNP	T	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr8:110131311T>G	uc003ymz.3	+	2	840	c.824T>G	c.(823-825)TTT>TGT	p.F275C		NM_003301	NP_003292	P34981	TRFR_HUMAN	thyrotropin-releasing hormone receptor	275	Helical; Name=6; (Potential).					integral to plasma membrane	thyrotropin-releasing hormone receptor activity			skin(2)|lung(1)	3			OV - Ovarian serous cystadenocarcinoma(57;2.3e-11)			GTAATTCTGTTTGCCCTTTTA	0.408													38	375					0	0	0	0
CSMD3	114788	broad.mit.edu	37	8	113842012	113842012	+	Missense_Mutation	SNP	G	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr8:113842012G>T	uc003ynu.2	-	12	1921	c.1762C>A	c.(1762-1764)CAG>AAG	p.Q588K	CSMD3_uc003ynt.2_Missense_Mutation_p.Q548K|CSMD3_uc011lhx.1_Missense_Mutation_p.Q484K	NM_198123	NP_937756	Q7Z407	CSMD3_HUMAN	CUB and Sushi multiple domains 3 isoform 1	588	Extracellular (Potential).|CUB 3.					integral to membrane|plasma membrane				ovary(21)|lung(11)|skin(11)|kidney(8)|large_intestine(6)|upper_aerodigestive_tract(2)|central_nervous_system(2)|urinary_tract(1)|breast(1)	63						AAATTTATCTGGATAACCTAG	0.388										HNSCC(6;0.00088)|TCGA Ovarian(7;0.080)			5	29					0.000602214	0.00296866	1	0
ZNF572	137209	broad.mit.edu	37	8	125989980	125989980	+	Silent	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr8:125989980C>T	uc003yrr.2	+	3	1625	c.1470C>T	c.(1468-1470)CAC>CAT	p.H490H		NM_152412	NP_689625	Q7Z3I7	ZN572_HUMAN	zinc finger protein 572	490	C2H2-type 12.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			large_intestine(1)|ovary(1)	2	Ovarian(258;0.0028)|all_neural(195;0.00294)|Hepatocellular(40;0.108)		STAD - Stomach adenocarcinoma(47;0.000918)|COAD - Colon adenocarcinoma(160;0.205)			GGAAAATTCACGTAGAAAAGC	0.473										HNSCC(60;0.17)			18	183					0	0	0	0
LOC442421	442421	broad.mit.edu	37	9	66500871	66500871	+	RNA	SNP	T	C	C	rs11262348		TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr9:66500871T>C	uc004aed.1	+	3		c.964T>C								Homo sapiens similar to prostaglandin E receptor 4, subtype EP4; PGE receptor, EP4 subtype; prostaglandin E2 receptor, mRNA (cDNA clone IMAGE:5288780).												0						TACACGGAACTGCTGTTGGTC	0.597													3	20					0	0	0	0
CBWD6	644019	broad.mit.edu	37	9	69238242	69238242	+	Missense_Mutation	SNP	C	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr9:69238242C>T	uc004afj.3	-	8	756	c.650G>A	c.(649-651)AGA>AAA	p.R217K	CBWD6_uc004afk.3_Intron|CBWD6_uc011lrf.1_Intron	NM_001085457	NP_001078926	Q4V339	CBWD6_HUMAN	COBW domain containing 6	217							ATP binding				0						AAGTGTCGTTCTTAATTTCTT	0.333													36	53					0	0	0	0
FRMD3	257019	broad.mit.edu	37	9	85863354	85863354	+	Missense_Mutation	SNP	C	G	G			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr9:85863354C>G	uc004ams.1	-	14	1475	c.1273G>C	c.(1273-1275)GAA>CAA	p.E425Q	FRMD3_uc004amr.1_Missense_Mutation_p.E411Q|FRMD3_uc004amq.1_Missense_Mutation_p.E82Q	NM_174938	NP_777598	A2A2Y4	FRMD3_HUMAN	FERM domain containing 3	425						cytoplasm|cytoskeleton|extrinsic to membrane|integral to membrane	cytoskeletal protein binding			ovary(1)|central_nervous_system(1)	2						GGGGGATCTTCATACTCCCGG	0.468													12	37					0	0	0	0
IL1RAPL1	11141	broad.mit.edu	37	X	29973844	29973844	+	Silent	SNP	G	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chrX:29973844G>A	uc004dby.2	+	11	2506	c.1998G>A	c.(1996-1998)TCG>TCA	p.S666S		NM_014271	NP_055086	Q9NZN1	IRPL1_HUMAN	interleukin 1 receptor accessory protein-like 1	666	Cytoplasmic (Potential).				innate immune response|negative regulation of calcium ion transport via voltage-gated calcium channel activity|negative regulation of exocytosis|regulation of neuron projection development	cytoplasm|integral to membrane|plasma membrane	protein binding|transmembrane receptor activity			ovary(3)|lung(1)|pancreas(1)	5						AGACAAAATCGAGCAGGGAGC	0.527													7	7					0	0	0	0
LPAR3	23566	broad.mit.edu	37	1	85331609	85331609	+	Frame_Shift_Del	DEL	G	-	-			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr1:85331609delG	uc001dkl.2	-	1	234	c.195delC	c.(193-195)TTCfs	p.F65fs	LPAR3_uc009wcj.1_Frame_Shift_Del_p.F65fs	NM_012152	NP_036284	Q9UBY5	LPAR3_HUMAN	lysophosphatidic acid receptor 3	65	Cytoplasmic (Potential).				G-protein signaling, coupled to cyclic nucleotide second messenger|synaptic transmission	integral to plasma membrane|intracellular membrane-bounded organelle				lung(3)|ovary(2)	5						ACAGGTAGTAGAAGGGGAAAT	0.393													---	---	---							
Unknown	0	broad.mit.edu	37	1	113433615	113433616	+	IGR	INS	-	T	T			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr1:113433615_113433616insT								FAM19A3 (163761 upstream) : SLC16A1 (20856 downstream)																							ttattcacttattttttttttt	0.208													---	---	---							
Unknown	0	broad.mit.edu	37	12	69594093	69594102	+	IGR	DEL	AGAAAGAGAT	-	-	rs80081772		TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr12:69594093_69594102delAGAAAGAGAT								CPM (237073 upstream) : CPSF6 (39215 downstream)																							ataagagataagaaagagataagagataag	0.024													---	---	---							
MUDENG	55745	broad.mit.edu	37	14	57741158	57741159	+	Frame_Shift_Ins	INS	-	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr14:57741158_57741159insA	uc001xcv.2	+	2	698_699	c.271_272insA	c.(271-273)GAAfs	p.E91fs	MUDENG_uc001xcu.3_Frame_Shift_Ins_p.E91fs|MUDENG_uc010tri.1_Intron|MUDENG_uc010trj.1_5'UTR	NM_018229	NP_060699	Q9H0R1	MUDEN_HUMAN	Mu-2 related death-inducing protein	91					intracellular protein transport|vesicle-mediated transport	clathrin adaptor complex				ovary(1)	1						GATAGGAGGTGAAGAACTCTGG	0.406													---	---	---							
MAP3K9	4293	broad.mit.edu	37	14	71275774	71275776	+	In_Frame_Del	DEL	CCT	-	-	rs3832971		TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr14:71275774_71275776delCCT	uc001xmm.2	-	1	113_115	c.113_115delAGG	c.(112-117)GAGGCG>GCG	p.E38del	MAP3K9_uc001xml.2_In_Frame_Del_p.E38del	NM_033141	NP_149132	P80192	M3K9_HUMAN	mitogen-activated protein kinase kinase kinase	38	Ala-rich.|Poly-Glu.				activation of JUN kinase activity|protein autophosphorylation		ATP binding|JUN kinase kinase kinase activity|MAP kinase kinase activity|protein homodimerization activity			stomach(2)|lung(1)|central_nervous_system(1)|skin(1)	5				all cancers(60;0.00779)|BRCA - Breast invasive adenocarcinoma(234;0.00884)|OV - Ovarian serous cystadenocarcinoma(108;0.08)		GCCGCCGCCGcctcctcctcctc	0.680													---	---	---							
JAG2	3714	broad.mit.edu	37	14	105613864	105613864	+	Frame_Shift_Del	DEL	T	-	-			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr14:105613864delT	uc001yqg.2	-	19	2770	c.2366delA	c.(2365-2367)AATfs	p.N789fs	JAG2_uc010axf.2_5'Flank|JAG2_uc001yqf.2_Frame_Shift_Del_p.N193fs|JAG2_uc001yqh.2_Frame_Shift_Del_p.N751fs	NM_002226	NP_002217	Q9Y219	JAG2_HUMAN	jagged 2 isoform a precursor	789	Extracellular (Potential).|EGF-like 15; calcium-binding (Potential).				auditory receptor cell fate commitment|cell communication|cell cycle|Notch receptor processing|Notch signaling pathway|regulation of cell migration|regulation of cell proliferation|spermatogenesis|thymic T cell selection	integral to plasma membrane	calcium ion binding|growth factor activity|Notch binding			lung(3)|breast(2)	5		all_cancers(154;0.0336)|all_epithelial(191;0.0729)|Melanoma(154;0.155)	OV - Ovarian serous cystadenocarcinoma(23;0.00989)|all cancers(16;0.0114)|Epithelial(46;0.0272)	Epithelial(152;0.047)|OV - Ovarian serous cystadenocarcinoma(161;0.148)|all cancers(159;0.208)		GTCGTTGGTATCTGGTTTGGG	0.652													---	---	---							
Unknown	0	broad.mit.edu	37	15	20148696	20148697	+	IGR	INS	-	A	A			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr15:20148696_20148697insA								None (None upstream) : GOLGA6L6 (588397 downstream)																							ATTTTGTCCGCCGCCGCCGCGG	0.574													---	---	---							
CGB	1082	broad.mit.edu	37	19	49528886	49528886	+	5'Flank	DEL	C	-	-	rs36051701		TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr19:49528886delC	uc002plv.1	-						CGB_uc010yad.1_Intron|CGB_uc002plu.1_5'Flank	NM_000737	NP_000728	P01233	CGHB_HUMAN	chorionic gonadotropin beta 3 subunit precursor						apoptosis|cell-cell signaling|cellular nitrogen compound metabolic process|female gamete generation|hormone biosynthetic process|peptide hormone processing|signal transduction	extracellular region|soluble fraction	hormone activity				0		all_epithelial(76;9.62e-07)|all_lung(116;1.7e-06)|Lung NSC(112;3.55e-06)|all_neural(266;0.0189)|Ovarian(192;0.0261)		all cancers(93;0.000371)|OV - Ovarian serous cystadenocarcinoma(262;0.000503)|GBM - Glioblastoma multiforme(486;0.00518)|Epithelial(262;0.0427)	Choriogonadotropin alfa(DB00097)	CCGGCGGCAGCCCCCTCCACC	0.657													---	---	---							
MZF1	7593	broad.mit.edu	37	19	59073795	59073796	+	Frame_Shift_Ins	INS	-	C	C			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr19:59073795_59073796insC	uc002qto.2	-	6	2409_2410	c.1848_1849insG	c.(1846-1851)CAGAGGfs	p.Q616fs	LOC100131691_uc002qtm.2_Intron|MZF1_uc002qtn.2_Frame_Shift_Ins_p.Q616fs	NM_198055	NP_932172	P28698	MZF1_HUMAN	zinc finger protein 42 isoform 2	616_617	C2H2-type 9.				viral reproduction	nucleus	protein homodimerization activity|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|zinc ion binding			ovary(1)	1		all_cancers(17;4.4e-22)|all_epithelial(17;2.15e-16)|Lung NSC(17;1.24e-06)|all_lung(17;5.41e-06)|Colorectal(82;3.46e-05)|Renal(17;0.00179)|all_neural(62;0.00607)|Ovarian(87;0.0443)|Breast(46;0.0928)|Medulloblastoma(540;0.184)		UCEC - Uterine corpus endometrioid carcinoma (67;0.0443)|all cancers(4;7.92e-14)|Epithelial(4;5.57e-11)|OV - Ovarian serous cystadenocarcinoma(4;1.13e-09)|GBM - Glioblastoma multiforme(193;0.0108)|Lung(386;0.182)		GTGTGTGTCCTCTGATGACGCG	0.663													---	---	---							
SCARF2	91179	broad.mit.edu	37	22	20781751	20781752	+	Frame_Shift_Ins	INS	-	GGACC	GGACC			TCGA-D6-6823-01A-11D-1912-08	TCGA-D6-6823-10A-01D-1912-08									Somatic	Phase_I	Capture				Illumina GAIIx	e1f4d8ef-f24a-417b-bf22-c03cdb6b5275	be1499ee-5b0d-4f5e-bac3-c6f6c552f4a6	g.chr22:20781751_20781752insGGACC	uc002zsj.1	-	10	1746_1747	c.1641_1642insGGTCC	c.(1639-1644)TCCTCTfs	p.S547fs	SCARF2_uc002zsk.1_Frame_Shift_Ins_p.S542fs	NM_153334	NP_699165	Q96GP6	SREC2_HUMAN	scavenger receptor class F, member 2 isoform 1	542_543	Cytoplasmic (Potential).				cell adhesion	integral to membrane	protein binding|receptor activity			breast(1)	1	Melanoma(16;0.000465)|Ovarian(15;0.00167)|Colorectal(54;0.0221)|all_neural(72;0.219)	Lung SC(17;0.0262)	LUSC - Lung squamous cell carcinoma(15;0.00102)|Lung(15;0.0173)			GAGGCCCGAGAGGACCAGGATG	0.599													---	---	---							
