Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
PRDM8	56978	broad.mit.edu	37	4	81123252	81123252	+	Missense_Mutation	SNP	G	G	C			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr4:81123252G>C	ENST00000339711.4	+	10	1867	c.636G>C	c.(634-636)caG>caC	p.Q212H	PRDM8_ENST00000415738.2_Missense_Mutation_p.Q212H|PRDM8_ENST00000504452.1_Missense_Mutation_p.Q212H	NM_020226.3	NP_064611.3	Q9NQV8	PRDM8_HUMAN	PR domain containing 8	212	Gly-rich.|Poly-Gln.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(2)|central_nervous_system(1)|endometrium(1)|large_intestine(2)|lung(2)|skin(2)	10						gcaaagaccagcagcagcagc	0.652000											OREG0016246	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	6	59					0	0	1	0	0
SPATA18	132671	broad.mit.edu	37	4	52927028	52927028	+	Missense_Mutation	SNP	G	G	A			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr4:52927028G>A	ENST00000295213.4	+	3	648	c.274G>A	c.(274-276)Gga>Aga	p.G92R	SPATA18_ENST00000419395.2_Missense_Mutation_p.G92R|SPATA18_ENST00000506829.1_Intron	NM_145263.2	NP_660306.1	Q8TC71	MIEAP_HUMAN	spermatogenesis associated 18	92					mitochondrial protein catabolic process|mitochondrion degradation by induced vacuole formation|response to DNA damage stimulus	mitochondrial outer membrane	protein binding			breast(1)|endometrium(3)|kidney(2)|large_intestine(8)|lung(20)|ovary(2)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)	41			GBM - Glioblastoma multiforme(4;1.77e-13)|LUSC - Lung squamous cell carcinoma(32;0.00204)			TGCTTCCCTGGGAAAATCTGT	0.468000													3	56					0	0	1	0	0
CROCCP2	0	broad.mit.edu	37	1	16953672	16953672	+	RNA	SNP	C	C	T	rs3738597	by1000genomes	TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr1:16953672C>T	ENST00000412962.1	-	0	589																											TCGGTCTTCTCGGCCTGCAGC	0.652000													9	46					0	0	1	0	0
PPP1R16B	26051	broad.mit.edu	37	20	37536550	37536550	+	Missense_Mutation	SNP	C	C	T			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr20:37536550C>T	ENST00000299824.1	+	9	1189	c.1000C>T	c.(1000-1002)Cgg>Tgg	p.R334W	PPP1R16B_ENST00000373331.2_Missense_Mutation_p.R292W	NM_015568.2	NP_056383.1	Q96T49	PP16B_HUMAN	protein phosphatase 1, regulatory subunit 16B	334					regulation of filopodium assembly|signal transduction	nucleus|plasma membrane	protein phosphatase binding			biliary_tract(1)|endometrium(4)|kidney(3)|large_intestine(10)|lung(23)|prostate(2)|skin(4)|upper_aerodigestive_tract(2)	49		Myeloproliferative disorder(115;0.00878)				ATCCTTGAGCCGGAGGACCTC	0.607000													4	47					0	0	1	0	0
KCNH2	3757	broad.mit.edu	37	7	150647430	150647430	+	Missense_Mutation	SNP	G	G	C			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr7:150647430G>C	ENST00000392968.2	-	7	3056	c.1936C>G	c.(1936-1938)Ccc>Gcc	p.P646A	KCNH2_ENST00000330883.4_Missense_Mutation_p.P402A|KCNH2_ENST00000262186.5_Missense_Mutation_p.P742A|KCNH2_ENST00000430723.3_Missense_Mutation_p.P742A			Q12809	KCNH2_HUMAN	potassium voltage-gated channel, subfamily H (eag-related), member 2	742					blood circulation|muscle contraction|regulation of heart contraction|regulation of transcription, DNA-dependent	voltage-gated potassium channel complex	delayed rectifier potassium channel activity|two-component sensor activity			NS(1)|cervix(1)|endometrium(10)|kidney(1)|large_intestine(5)|lung(14)|ovary(1)|prostate(2)|skin(6)|upper_aerodigestive_tract(1)	42	all_neural(206;0.219)		OV - Ovarian serous cystadenocarcinoma(82;0.0121)	UCEC - Uterine corpus endometrioid carcinoma (81;0.168)	Amiodarone(DB01118)|Amsacrine(DB00276)|Astemizole(DB00637)|Carvedilol(DB01136)|Cisapride(DB00604)|Dofetilide(DB00204)|Halofantrine(DB01218)|Ibutilide(DB00308)|Pimozide(DB01100)|Propafenone(DB01182)|Quinidine(DB00908)|Sertindole(DB06144)|Sotalol(DB00489)|Terfenadine(DB00342)|Verapamil(DB00661)	CCTCGGAAGGGTTTGCAGTGC	0.652000													4	87					0	0	1	0	0
ZNF207	7756	broad.mit.edu	37	17	30685544	30685544	+	Missense_Mutation	SNP	C	C	T			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr17:30685544C>T	ENST00000394670.4	+	3	360	c.191C>T	c.(190-192)gCc>gTc	p.A64V	ZNF207_ENST00000342555.6_Missense_Mutation_p.A67V|ZNF207_ENST00000394673.2_Missense_Mutation_p.A64V|ZNF207_ENST00000577908.1_Missense_Mutation_p.A64V|RP11-227G15.3_ENST00000581915.1_RNA|ZNF207_ENST00000321233.6_Missense_Mutation_p.A64V|ZNF207_ENST00000341711.6_Intron	NM_001098507.1	NP_001091977.1	O43670	ZN207_HUMAN	zinc finger protein 207	64						nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding	p.A64G(1)		breast(1)|endometrium(2)|kidney(2)|lung(3)|urinary_tract(2)	10		Breast(31;0.116)|Ovarian(249;0.182)	BRCA - Breast invasive adenocarcinoma(9;0.239)			ACAATAGATGCCGTACCAAAT	0.323000													4	76					0	0	1	0	0
PRKG1	5592	broad.mit.edu	37	10	54042040	54042040	+	Missense_Mutation	SNP	C	C	T			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr10:54042040C>T	ENST00000373980.4	+	14	2090	c.1673C>T	c.(1672-1674)tCa>tTa	p.S558L	PRKG1_ENST00000401604.2_Missense_Mutation_p.S543L|PRKG1_ENST00000373985.1_Missense_Mutation_p.S531L|PRKG1-AS1_ENST00000452247.2_RNA|PRKG1_ENST00000373975.2_Missense_Mutation_p.S261L|PRKG1-AS1_ENST00000426785.2_RNA	NM_006258.3	NP_006249.1	Q13976	KGP1_HUMAN	protein kinase, cGMP-dependent, type I	543	Protein kinase.				actin cytoskeleton organization|platelet activation|signal transduction	cytosol	ATP binding|cGMP binding|cGMP-dependent protein kinase activity			autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(11)|lung(23)|ovary(1)|prostate(1)|skin(5)|stomach(1)|upper_aerodigestive_tract(2)	53		all_cancers(4;2.13e-08)|all_epithelial(4;2.44e-08)|all_lung(4;0.000173)		all cancers(4;1.18e-05)|GBM - Glioblastoma multiforme(4;0.000359)|Epithelial(53;0.00532)|Lung(62;0.0606)		GACTACTGGTCACTGGGAATC	0.453000													4	68					0	0	1	0	0
TUBBP5	0	broad.mit.edu	37	9	141070915	141070915	+	RNA	SNP	C	C	T			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr9:141070915C>T	ENST00000503395.1	+	0	1690																		p.T178T(1)									TGTCAGACACCGTGGTGGAGC	0.522000													3	62					0	0	1	0	0
TAP1	6890	broad.mit.edu	37	6	32813387	32813387	+	Missense_Mutation	SNP	A	A	G			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr6:32813387A>G	ENST00000354258.4	-	11	2557	c.2396T>C	c.(2395-2397)aTg>aCg	p.M799T	TAPSAR1_ENST00000453426.1_lincRNA|PSMB9_ENST00000395330.1_Intron|TAP1_ENST00000425148.2_Missense_Mutation_p.M538T	NM_000593.5	NP_000584.2	Q03518	TAP1_HUMAN	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	799	ABC transporter.				antigen processing and presentation of endogenous peptide antigen via MHC class I|cytosol to ER transport|intracellular transport of viral proteins in host cell|positive regulation of T cell mediated cytotoxicity	cytosol|plasma membrane|TAP complex	ADP binding|ATP binding|MHC class I protein binding|oligopeptide-transporting ATPase activity|peptide antigen binding|protein homodimerization activity|TAP1 binding|TAP2 binding|tapasin binding			breast(2)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(10)|lung(4)|prostate(1)|skin(1)	21						AGCCTGCACCATGGCCCAGTA	0.582000													3	37					0	0	1	0	0
KANK1	23189	broad.mit.edu	37	9	732477	732477	+	Silent	SNP	G	G	A			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr9:732477G>A	ENST00000382303.1	+	10	3757	c.3105G>A	c.(3103-3105)gaG>gaA	p.E1035E	KANK1_ENST00000489369.1_3'UTR|KANK1_ENST00000382297.2_Silent_p.E1035E|KANK1_ENST00000382293.3_Silent_p.E877E	NM_001256876.1	NP_001243805.1	Q14678	KANK1_HUMAN	KN motif and ankyrin repeat domains 1	1035					negative regulation of actin filament polymerization	cytoplasm				autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(7)|kidney(3)|large_intestine(9)|lung(8)|ovary(3)|pancreas(1)|prostate(3)|stomach(4)|upper_aerodigestive_tract(1)	43		Lung NSC(10;9.84e-12)|all_lung(10;1.02e-11)|Breast(48;0.128)		Epithelial(6;0.000153)|OV - Ovarian serous cystadenocarcinoma(1;0.000358)|Lung(218;0.0222)		TTGAAGAAGAGGAGGAGGAGG	0.468000													4	95					0	0	1	0	0
ATAD3B	83858	broad.mit.edu	37	1	1425747	1425747	+	Missense_Mutation	SNP	G	G	A			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr1:1425747G>A	ENST00000308647.7	+	14	1564	c.1448G>A	c.(1447-1449)cGc>cAc	p.R483H		NM_031921.4	NP_114127.3	Q5T9A4	ATD3B_HUMAN	ATPase family, AAA domain containing 3B	483							ATP binding|nucleoside-triphosphatase activity			endometrium(2)|large_intestine(1)|lung(3)|ovary(1)|skin(2)|urinary_tract(1)	10	all_cancers(77;0.00164)|all_epithelial(69;0.000959)|all_lung(157;0.00963)|Lung NSC(156;0.0232)|Ovarian(185;0.0634)	all_epithelial(116;9.48e-15)|all_lung(118;9.67e-07)|Lung NSC(185;5.59e-05)|Renal(390;0.00571)|Breast(487;0.0183)|Hepatocellular(190;0.0268)|Myeloproliferative disorder(586;0.028)|Ovarian(437;0.127)|Lung SC(97;0.217)		Epithelial(90;1.79e-36)|OV - Ovarian serous cystadenocarcinoma(86;3.94e-22)|Colorectal(212;0.000155)|COAD - Colon adenocarcinoma(227;0.000193)|Kidney(185;0.00227)|BRCA - Breast invasive adenocarcinoma(365;0.00461)|STAD - Stomach adenocarcinoma(132;0.00644)|KIRC - Kidney renal clear cell carcinoma(229;0.0339)|Lung(427;0.145)		GAGCGGGAGCGCCTGGTGAGA	0.592000													3	55					0	0	1	0	0
KLHL41	10324	broad.mit.edu	37	2	170367317	170367317	+	Missense_Mutation	SNP	G	G	C			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr2:170367317G>C	ENST00000284669.1	+	1	1106	c.1029G>C	c.(1027-1029)caG>caC	p.Q343H	BBS5_ENST00000554017.1_Intron|RP11-724O16.1_ENST00000513963.1_Intron	NM_006063.2	NP_006054.2			kelch-like family member 41																		TTGTTACCCAGCAAAATCAGA	0.423000													3	69					0	0	1	0	0
RP11-423O2.5	0	broad.mit.edu	37	1	142803646	142803646	+	RNA	SNP	G	G	A			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr1:142803646G>A	ENST00000423385.1	-	0	1319																											gttgtattctgggctagacat	0.299000													10	54					0	0	1	0	0
NRXN1	9378	broad.mit.edu	37	2	50765424	50765424	+	Nonsense_Mutation	SNP	C	C	A			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr2:50765424C>A	ENST00000404971.1	-	11	3569	c.2230G>T	c.(2230-2232)Gga>Tga	p.G744*	NRXN1_ENST00000406859.3_Nonsense_Mutation_p.G704*|NRXN1_ENST00000402717.3_Nonsense_Mutation_p.G696*|NRXN1_ENST00000401669.2_Nonsense_Mutation_p.G704*|NRXN1_ENST00000406316.2_Nonsense_Mutation_p.G704*|NRXN1_ENST00000331040.5_5'UTR|NRXN1_ENST00000405472.3_Nonsense_Mutation_p.G696*	NM_001135659.1	NP_001129131.1	Q9ULB1	NRX1A_HUMAN	neurexin 1	704	Laminin G-like 4.				adult behavior|axon guidance|cell adhesion|grooming behavior|learning|neuromuscular process controlling balance|positive regulation of excitatory postsynaptic membrane potential|prepulse inhibition	cell surface|integral to plasma membrane	metal ion binding|protein binding|receptor activity			breast(1)|endometrium(3)|kidney(3)|large_intestine(10)|lung(33)|ovary(3)|prostate(1)|skin(2)|upper_aerodigestive_tract(2)	58		all_hematologic(82;0.152)|Acute lymphoblastic leukemia(82;0.192)	Lung(47;0.0813)|LUSC - Lung squamous cell carcinoma(58;0.116)			TAGCCTGTTCCGGAACAATCA	0.463000													4	176					2.56e-06	2.98667e-06	1	1	0
BBS4	585	broad.mit.edu	37	15	73004613	73004613	+	Missense_Mutation	SNP	C	C	A			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr15:73004613C>A	ENST00000268057.4	+	4	226	c.185C>A	c.(184-186)aCt>aAt	p.T62N	BBS4_ENST00000564239.1_3'UTR|BBS4_ENST00000395205.2_Missense_Mutation_p.T70N|BBS4_ENST00000539603.1_Missense_Mutation_p.T50N|BBS4_ENST00000542334.1_5'UTR	NM_033028.4	NP_149017.2	Q96RK4	BBS4_HUMAN	Bardet-Biedl syndrome 4	62	Required for localization to centrosomes.				adult behavior|brain morphogenesis|cell cycle cytokinesis|centrosome organization|cerebral cortex development|convergent extension involved in gastrulation|dendrite development|fat cell differentiation|heart looping|hippocampus development|intracellular transport|maintenance of protein location in nucleus|melanosome transport|microtubule anchoring at centrosome|neural tube closure|nonmotile primary cilium assembly|photoreceptor cell maintenance|pigment granule aggregation in cell center|positive regulation of flagellum assembly|regulation of cilium beat frequency involved in ciliary motility|regulation of cytokinesis|regulation of lipid metabolic process|retina homeostasis|retinal rod cell development|sensory perception of smell|sensory processing|spermatid development|striatum development	BBSome|centriolar satellite|centriole|cilium membrane|microtubule basal body|motile cilium|nonmotile primary cilium|nucleus|pericentriolar material	alpha-tubulin binding|beta-tubulin binding|dynactin binding|microtubule motor activity			autonomic_ganglia(1)|biliary_tract(1)|breast(1)|endometrium(1)|kidney(1)|large_intestine(4)|lung(7)|prostate(2)|urinary_tract(1)	19						CTTCAAGAGACTCAGGGATTG	0.378000									Bardet-Biedl syndrome				3	54					0.004672	0.00511	1	1	0
IGKV1D-16	0	broad.mit.edu	37	2	90139477	90139477	+	RNA	SNP	G	G	A	rs2848291	by1000genomes	TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr2:90139477G>A	ENST00000492446.1	+	0	275																											GTCCCATCAAGGTTCAGCGGC	0.483000													4	186					0	0	1	0	0
ABHD8	79575	broad.mit.edu	37	19	17412031	17412031	+	Missense_Mutation	SNP	G	G	A			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr19:17412031G>A	ENST00000247706.3	-	2	634	c.395C>T	c.(394-396)gCc>gTc	p.A132V	MRPL34_ENST00000600434.1_Intron|MRPL34_ENST00000595444.1_Intron	NM_024527.4	NP_078803.4	Q96I13	ABHD8_HUMAN	abhydrolase domain containing 8	132							hydrolase activity			central_nervous_system(1)|endometrium(1)|kidney(1)|lung(5)|urinary_tract(1)	9						gctgccgGGGGCCAAGCGGCC	0.726000													3	42					0	0	1	0	0
RP11-337C18.8	0	broad.mit.edu	37	1	146651056	146651056	+	RNA	SNP	C	C	G			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr1:146651056C>G	ENST00000607149.1	+	0	350				RP11-337C18.8_ENST00000606757.1_RNA|RP11-337C18.10_ENST00000606856.1_RNA																							CCATATACTTCTCTCCAGCCA	0.418000													5	77					0	0	1	0	0
CACNA1E	777	broad.mit.edu	37	1	181745336	181745336	+	Missense_Mutation	SNP	G	G	A			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr1:181745336G>A	ENST00000526775.1	+	37	5347	c.5182G>A	c.(5182-5184)Gtc>Atc	p.V1728I	CACNA1E_ENST00000360108.3_Missense_Mutation_p.V1728I|CACNA1E_ENST00000358338.5_Missense_Mutation_p.V1679I|CACNA1E_ENST00000367567.4_Missense_Mutation_p.V1354I|CACNA1E_ENST00000367573.2_Missense_Mutation_p.V1747I|CACNA1E_ENST00000367570.1_Missense_Mutation_p.V1747I|CACNA1E_ENST00000357570.5_Missense_Mutation_p.V1698I	NM_001205294.1	NP_001192223.1	Q15878	CAC1E_HUMAN	calcium channel, voltage-dependent, R type, alpha 1E subunit	1747					energy reserve metabolic process|membrane depolarization|synaptic transmission	voltage-gated calcium channel complex	voltage-gated calcium channel activity			NS(2)|breast(9)|central_nervous_system(3)|cervix(1)|endometrium(22)|haematopoietic_and_lymphoid_tissue(6)|kidney(4)|large_intestine(34)|lung(99)|ovary(6)|pancreas(1)|prostate(9)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	204						GTTTGTCCGCGTCTGGGCAGA	0.612000													5	156					0	0	1	0	0
SKIL	6498	broad.mit.edu	37	3	170078822	170078822	+	Silent	SNP	C	C	A			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr3:170078822C>A	ENST00000458537.3	+	1	1412	c.703C>A	c.(703-705)Cgg>Agg	p.R235R	SKIL_ENST00000259119.4_Silent_p.R235R|SKIL_ENST00000413427.2_Silent_p.R235R|SKIL_ENST00000426052.2_Silent_p.R215R	NM_001145097.2|NM_001248008.1|NM_005414.4	NP_001138569.1|NP_001234937.1|NP_005405.2	P12757	SKIL_HUMAN	SKI-like oncogene	235					cell cycle arrest|negative regulation of cell differentiation|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transforming growth factor beta receptor signaling pathway|positive regulation of axonogenesis|protein heterotrimerization|protein homotrimerization|regulation of apoptosis|response to antibiotic|response to growth factor stimulus|skeletal muscle tissue development	cytoplasm|PML body	chromatin binding|nucleotide binding|protein complex binding|protein domain specific binding|SMAD binding|transcription corepressor activity|transcription repressor activity			cervix(1)|endometrium(2)|kidney(2)|large_intestine(1)|lung(12)|ovary(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	25	all_cancers(22;7.13e-23)|all_epithelial(15;9.95e-28)|all_lung(20;1.23e-16)|Lung NSC(18;5.15e-16)|Ovarian(172;0.000337)|Breast(254;0.137)		Lung(28;2.71e-13)|STAD - Stomach adenocarcinoma(35;0.197)			TGCTTTATTGCGGCCACGAAC	0.433000													4	145					0.00909568	0.0093632	1	1	0
CTC-228N24.1	0	broad.mit.edu	37	5	127122030	127122030	+	RNA	DEL	A	A	-			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr5:127122030delA	ENST00000514853.2	+	0	278																											TCTGTGACAGAAAAAAAAAAG	0.388													7	70	---	---	---	---					
BTN2A3P	0	broad.mit.edu	37	6	26428450	26428451	+	RNA	INS	-	-	A	rs139821417		TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr6:26428450_26428451insA	ENST00000466808.2	+	0	1304																											tgtgtctaattaaaaaaaaaaa	0.450													3	5	---	---	---	---					
XKR5	389610	broad.mit.edu	37	8	6673270	6673270	+	RNA	DEL	A	A	-			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr8:6673270delA	ENST00000518724.1	-	0	1071							Q6UX68	XKR5_HUMAN	XK, Kell blood group complex subunit-related family, member 5							integral to membrane				endometrium(1)|large_intestine(1)|lung(1)	3			STAD - Stomach adenocarcinoma(24;0.0984)	READ - Rectum adenocarcinoma(644;0.137)|COAD - Colon adenocarcinoma(149;0.166)		AGCCCATTGTAAAAAAAAAAA	0.502											OREG0018511	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	4	---	---	---	---					
LINC00539	0	broad.mit.edu	37	13	21894829	21894831	+	RNA	DEL	TGG	TGG	-			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr13:21894829_21894831delTGG	ENST00000434601.3	-	0	473																											CAGAAGGGGATGGTGGAGACTGA	0.591													6	9	---	---	---	---					
RTL1	388015	broad.mit.edu	37	14	101350670	101350671	+	In_Frame_Ins	INS	-	-	TCT	rs55755518	by1000genomes	TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr14:101350670_101350671insTCT	ENST00000534062.1	-	1	513_514	c.455_456insAGA	c.(454-456)gag>gaAGAg	p.152_152E>EE		NM_001134888.2	NP_001128360.1	E9PKS8	E9PKS8_HUMAN	retrotransposon-like 1	152										breast(1)|endometrium(5)|kidney(4)|large_intestine(1)|lung(5)|pancreas(1)|prostate(2)|skin(2)	21						TCTGGTTTTGCTCTTGAGGAGT	0.520													5	3	---	---	---	---					
SNX29P2	0	broad.mit.edu	37	16	29372348	29372348	+	RNA	DEL	T	T	-			TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr16:29372348delT	ENST00000398878.3	+	0	1186				SNX29P2_ENST00000507381.1_RNA																							TGGGAGGttgttttttttttt	0.478													7	9	---	---	---	---					
GALR2	8811	broad.mit.edu	37	17	74073448	74073457	+	Frame_Shift_Del	DEL	GTCCTGGCCC	GTCCTGGCCC	-	rs67693166		TCGA-EJ-A8FP-01A-21D-A364-08	TCGA-EJ-A8FP-10A-01D-A362-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	ac97df1b-05e5-4a00-a8b6-62d758397f3b	2f1be801-cd94-47b5-90b7-e2aea915e66b	g.chr17:74073448_74073457delGTCCTGGCCC	ENST00000329003.3	+	2	1190_1199	c.1100_1109delGTCCTGGCCC	c.(1099-1110)tgtcctggcccgfs	p.CPGP367fs		NM_003857.2	NP_003848.1	O43603	GALR2_HUMAN	galanin receptor 2	367					digestion|elevation of cytosolic calcium ion concentration|feeding behavior|learning or memory|muscle contraction	integral to membrane|plasma membrane	galanin receptor activity			cervix(1)|lung(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	8						CTCGAGCCCTGTCCTGGCCCGTCCTGGCAG	0.657													4	7	---	---	---	---					
