Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
FHL1	2273	broad.mit.edu	37	X	135290740	135290740	+	Missense_Mutation	SNP	G	G	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chrX:135290740G>A	ENST00000543669.1	+	5	1339	c.628G>A	c.(628-630)Gtg>Atg	p.V210M	FHL1_ENST00000370676.3_Intron|FHL1_ENST00000535737.1_Missense_Mutation_p.V210M|FHL1_ENST00000370690.3_Missense_Mutation_p.V210M|FHL1_ENST00000370683.1_Missense_Mutation_p.V226M|FHL1_ENST00000394153.2_Missense_Mutation_p.V210M|FHL1_ENST00000539015.1_Missense_Mutation_p.V239M|FHL1_ENST00000394155.2_Missense_Mutation_p.V210M|FHL1_ENST00000345434.3_Missense_Mutation_p.V210M	NM_001159704.1	NP_001153176.1	Q13642	FHL1_HUMAN	four and a half LIM domains 1	210	LIM zinc-binding 3.				cell differentiation|cell growth|muscle organ development|organ morphogenesis	cytosol|nucleus|plasma membrane	protein binding|zinc ion binding			endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|large_intestine(3)|lung(10)|prostate(1)|upper_aerodigestive_tract(1)	19	Acute lymphoblastic leukemia(192;0.000127)					GTATTACTGCGTGGATTGCTA	0.527000													115	42					0	0	1	0	0
UGDH	7358	broad.mit.edu	37	4	39522980	39522980	+	Silent	SNP	A	A	G			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr4:39522980A>G	ENST00000316423.6	-	2	495	c.153T>C	c.(151-153)ccT>ccC	p.P51P	UGDH_ENST00000507089.1_Intron|UGDH_ENST00000515398.1_Intron|UGDH_ENST00000506179.1_Silent_p.P51P|UGDH_ENST00000501493.2_Silent_p.P51P	NM_001184701.1|NM_003359.3	NP_001171630.1|NP_003350.1	O60701	UGDH_HUMAN	UDP-glucose 6-dehydrogenase	51					glycosaminoglycan biosynthetic process|UDP-glucose metabolic process|UDP-glucuronate biosynthetic process|xenobiotic metabolic process	cytosol	electron carrier activity|NAD binding|UDP-glucose 6-dehydrogenase activity			breast(1)|central_nervous_system(1)|cervix(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(6)|lung(10)|ovary(3)|skin(1)|urinary_tract(2)	27					NADH(DB00157)	CCTCATAAATAGGAAGTGTAG	0.303000													13	84					0	0	1	0	0
PALM	5064	broad.mit.edu	37	19	726159	726159	+	Silent	SNP	G	G	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr19:726159G>A	ENST00000264560.7	+	2	221	c.27G>A	c.(25-27)acG>acA	p.T9T	PALM_ENST00000338448.5_Silent_p.T9T	NM_001040134.1	NP_001035224.1	O75781	PALM_HUMAN	paralemmin	9					cellular component movement|negative regulation of adenylate cyclase activity|negative regulation of dopamine receptor signaling pathway|positive regulation of filopodium assembly|regulation of cell shape	cytoplasmic membrane-bounded vesicle|filopodium membrane|integral to plasma membrane				endometrium(2)|large_intestine(1)|lung(4)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	11		all_epithelial(18;2.19e-21)|Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;3.55e-06)|all_lung(49;5.41e-06)|Breast(49;4.08e-05)|Hepatocellular(1079;0.137)|Renal(1328;0.228)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)|Lung(535;0.201)		CAGAGACCACGTCCCAGCAGG	0.672000													33	79					0	0	1	0	0
RP11-204M4.2	0	broad.mit.edu	37	9	41962602	41962602	+	RNA	SNP	G	G	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr9:41962602G>T	ENST00000454645.1	-	0	902					NR_003670.1																						TTCTTTCTTTGTTTTTTTTCC	0.373000													5	49					0.184627	0.188178	1	1	0
NCAPH	23397	broad.mit.edu	37	2	97019969	97019969	+	Missense_Mutation	SNP	G	G	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr2:97019969G>T	ENST00000455200.1	+	9	1313	c.1018G>T	c.(1018-1020)Gac>Tac	p.D340Y	NCAPH_ENST00000240423.4_Missense_Mutation_p.D351Y|NCAPH_ENST00000427946.1_Missense_Mutation_p.D215Y			Q15003	CND2_HUMAN	non-SMC condensin I complex, subunit H	351					cell division|mitotic chromosome condensation	condensin complex|cytoplasm|microtubule cytoskeleton|nucleus				haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(7)|lung(11)|ovary(1)|prostate(1)|skin(2)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	28		Ovarian(717;0.0221)				CCAGGTATTTGACATCAATGC	0.493000													56	147					1.72845e-40	1.99147e-40	1	1	0
MAML3	55534	broad.mit.edu	37	4	140811099	140811099	+	Splice_Site	SNP	C	C	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr4:140811099C>T	ENST00000398940.1	-	1	107	c.108G>A	c.(106-108)caG>caA	p.Q36Q	MAML3_ENST00000327122.5_Silent_p.Q341Q|MAML3_ENST00000509479.2_Silent_p.Q497Q			Q96JK9	MAML3_HUMAN	mastermind-like 3 (Drosophila)	497					Notch signaling pathway|positive regulation of transcription from RNA polymerase II promoter|transcription, DNA-dependent	nuclear speck	transcription coactivator activity	p.Q497Q(2)		breast(1)|endometrium(7)|kidney(2)|large_intestine(1)|lung(9)|ovary(1)|prostate(2)|urinary_tract(2)	25	all_hematologic(180;0.162)					gctgctgctgctgctgctgct	0.542000													4	71					0	0	1	0	0
CCT8L2	150160	broad.mit.edu	37	22	17073401	17073401	+	Missense_Mutation	SNP	G	G	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr22:17073401G>A	ENST00000359963.3	-	1	299	c.40C>T	c.(40-42)Cgg>Tgg	p.R14W		NM_014406.4	NP_055221.1	Q96SF2	TCPQM_HUMAN	chaperonin containing TCP1, subunit 8 (theta)-like 2	14					cellular protein metabolic process	cytoplasm	anion channel activity|ATP binding|calcium-activated potassium channel activity			breast(3)|endometrium(7)|kidney(1)|large_intestine(8)|liver(2)|lung(37)|ovary(3)|prostate(3)|skin(2)|stomach(1)	67	all_hematologic(4;0.00567)|Acute lymphoblastic leukemia(84;0.0977)	all_epithelial(15;0.0157)|Lung NSC(13;0.147)|all_lung(157;0.175)				AGTGCCAGCCGCTGGGGCAGC	0.637000													25	37					0	0	1	0	0
SLC11A1	6556	broad.mit.edu	37	2	219259418	219259418	+	Silent	SNP	G	G	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr2:219259418G>T	ENST00000233202.6	+	14	1792	c.1452G>T	c.(1450-1452)gtG>gtT	p.V484V	SLC11A1_ENST00000539932.1_Silent_p.V366V	NM_000578.3	NP_000569.3	P49279	NRAM1_HUMAN	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	484					activation of protein kinase activity|antigen processing and presentation of peptide antigen|cadmium ion transmembrane transport|cellular cadmium ion homeostasis|cellular iron ion homeostasis|defense response to Gram-negative bacterium|defense response to protozoan|divalent metal ion export|inflammatory response|interleukin-2 production|interleukin-3 production|iron ion transport|L-arginine import|macrophage activation|MHC class II biosynthetic process|mRNA stabilization|multicellular organismal iron ion homeostasis|negative regulation of cytokine production|nitrite transport|phagocytosis|positive regulation of dendritic cell antigen processing and presentation|positive regulation of interferon-gamma production|positive regulation of phagocytosis|positive regulation of T-helper 1 type immune response|positive regulation of transcription from RNA polymerase II promoter|respiratory burst|response to interferon-gamma|response to lipopolysaccharide|T cell cytokine production|T cell proliferation involved in immune response|vacuolar acidification|wound healing	integral to plasma membrane|late endosome membrane|lysosome|phagocytic vesicle membrane|tertiary granule membrane	manganese ion transmembrane transporter activity|metal ion:hydrogen antiporter activity|protein homodimerization activity			NS(1)|breast(2)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(2)|lung(3)|ovary(3)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)	19		Renal(207;0.0474)		Epithelial(149;1.16e-06)|all cancers(144;0.000195)|LUSC - Lung squamous cell carcinoma(224;0.008)|Lung(261;0.00942)		TCTACTTCGTGGTCAGCTATC	0.612000													12	121					9.31168e-06	1.02816e-05	1	1	0
FOXP2	93986	broad.mit.edu	37	7	114270015	114270015	+	Silent	SNP	A	A	G	rs146945410	byFrequency	TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr7:114270015A>G	ENST00000393500.3	+	11	1147	c.327A>G	c.(325-327)caA>caG	p.Q109Q	FOXP2_ENST00000393498.2_Silent_p.Q164Q|FOXP2_ENST00000350908.4_Silent_p.Q184Q|FOXP2_ENST00000403559.4_Silent_p.Q201Q|FOXP2_ENST00000393494.2_Silent_p.Q184Q|FOXP2_ENST00000393491.3_Silent_p.Q92Q|FOXP2_ENST00000360232.4_Silent_p.Q184Q|FOXP2_ENST00000390668.3_Silent_p.Q208Q|FOXP2_ENST00000393489.3_Silent_p.Q92Q|FOXP2_ENST00000408937.3_Silent_p.Q209Q|FOXP2_ENST00000378237.3_Silent_p.Q184Q			O15409	FOXP2_HUMAN	forkhead box P2	184	Gln-rich.				camera-type eye development|caudate nucleus development|cerebellum development|cerebral cortex development|embryo development|growth|lung alveolus development|negative regulation of transcription, DNA-dependent|pattern specification process|positive regulation of epithelial cell proliferation involved in lung morphogenesis|positive regulation of mesenchymal cell proliferation|post-embryonic development|putamen development|regulation of sequence-specific DNA binding transcription factor activity|righting reflex|skeletal muscle tissue development|smooth muscle tissue development|vocal learning	cytoplasm|transcription factor complex	chromatin binding|DNA bending activity|double-stranded DNA binding|promoter binding|protein heterodimerization activity|protein homodimerization activity|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding|zinc ion binding			breast(3)|endometrium(7)|kidney(4)|large_intestine(7)|lung(22)|ovary(4)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	52						agcagcagcaacagcagcagc	0.502000													4	76					0	0	1	0	0
AIM1	202	broad.mit.edu	37	6	106968542	106968542	+	Missense_Mutation	SNP	T	T	G			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr6:106968542T>G	ENST00000369066.3	+	2	2722	c.2235T>G	c.(2233-2235)gaT>gaG	p.D745E		NM_001624.2	NP_001615	Q9Y4K1	AIM1_HUMAN	absent in melanoma 1	745							sugar binding			breast(8)|central_nervous_system(1)|cervix(2)|endometrium(6)|kidney(7)|large_intestine(13)|lung(20)|ovary(5)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)	69	Breast(9;0.0138)|all_epithelial(6;0.169)	all_cancers(87;4.67e-25)|all_epithelial(87;5.46e-21)|Acute lymphoblastic leukemia(125;2.15e-07)|all_hematologic(75;5.28e-06)|Colorectal(196;3.46e-05)|all_lung(197;5.94e-05)|Lung NSC(302;7.26e-05)|Ovarian(999;0.00473)	Epithelial(6;0.00114)|all cancers(7;0.00726)|BRCA - Breast invasive adenocarcinoma(8;0.0114)|OV - Ovarian serous cystadenocarcinoma(5;0.0305)	all cancers(137;1.73e-50)|Epithelial(106;2.42e-48)|OV - Ovarian serous cystadenocarcinoma(136;1.51e-27)|BRCA - Breast invasive adenocarcinoma(108;0.00104)|GBM - Glioblastoma multiforme(226;0.00858)		AGGTGTTTGATCCCAAAGTGT	0.443000													4	104					0	0	1	0	0
SCNN1B	0	broad.mit.edu	37	16	23391983	23391983	+	Missense_Mutation	SNP	C	C	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr16:23391983C>T	ENST00000343070.2	+	13	1960	c.1784C>T	c.(1783-1785)gCc>gTc	p.A595V	SCNN1B_ENST00000568923.1_Missense_Mutation_p.A568V|SCNN1B_ENST00000307331.5_Missense_Mutation_p.A640V|SCNN1B_ENST00000568085.1_Missense_Mutation_p.A559V	NM_000336.2	NP_000327.2	P51168	SCNNB_HUMAN	sodium channel, non-voltage-gated 1, beta subunit	595					excretion|sensory perception of taste	apical plasma membrane	ligand-gated sodium channel activity|WW domain binding			breast(2)|endometrium(3)|kidney(2)|large_intestine(5)|liver(2)|lung(8)|ovary(3)|pancreas(1)|prostate(3)|skin(1)|stomach(1)|urinary_tract(1)	32				GBM - Glioblastoma multiforme(48;0.0465)	Amiloride(DB00594)|Triamterene(DB00384)	CCTGACACGGCCCCCCGCAGC	0.711000													26	59					0	0	1	0	0
OR5AK2	390181	broad.mit.edu	37	11	56756464	56756464	+	Missense_Mutation	SNP	A	A	G			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr11:56756464A>G	ENST00000326855.2	+	1	118	c.76A>G	c.(76-78)Atc>Gtc	p.I26V		NM_001005323.1	NP_001005323.1	Q8NH90	O5AK2_HUMAN	olfactory receptor, family 5, subfamily AK, member 2	26					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(3)|endometrium(1)|large_intestine(4)|lung(3)|ovary(3)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(2)	21						GTTTTGGTGTATCCTCTTCAT	0.398000													4	135					0	0	1	0	0
GJA4	2701	broad.mit.edu	37	1	35260022	35260022	+	Missense_Mutation	SNP	T	T	G			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr1:35260022T>G	ENST00000342280.4	+	2	296	c.208T>G	c.(208-210)Ttc>Gtc	p.F70V		NM_002060.2	NP_002051.2	P35212	CXA4_HUMAN	gap junction protein, alpha 4, 37kDa	70					cell-cell junction assembly	integral to plasma membrane				NS(1)|central_nervous_system(1)|endometrium(1)|large_intestine(3)|lung(3)|prostate(4)|stomach(1)	14		Myeloproliferative disorder(586;0.0255)|all_neural(195;0.234)				TGACCAGGCCTTCCCCATCTC	0.607000													5	112					0	0	1	0	0
NOS2	4843	broad.mit.edu	37	17	26099431	26099431	+	Missense_Mutation	SNP	C	C	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr17:26099431C>T	ENST00000313735.6	-	14	1840	c.1607G>A	c.(1606-1608)cGa>cAa	p.R536Q		NM_000625.4	NP_000616.3	P35228	NOS2_HUMAN	nitric oxide synthase 2, inducible	536					arginine catabolic process|defense response to Gram-negative bacterium|innate immune response in mucosa|nitric oxide biosynthetic process|peptidyl-cysteine S-nitrosylation|platelet activation|positive regulation of killing of cells of other organism|positive regulation of leukocyte mediated cytotoxicity|regulation of cellular respiration|regulation of insulin secretion|superoxide metabolic process	cytosol|nucleus	arginine binding|calmodulin binding|flavin adenine dinucleotide binding|FMN binding|heme binding|NADP binding|nitric-oxide synthase activity|protein homodimerization activity|tetrahydrobiopterin binding			autonomic_ganglia(1)|breast(2)|cervix(1)|endometrium(4)|kidney(3)|large_intestine(8)|lung(28)|ovary(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(3)	56					Dexamethasone(DB01234)|Hydrocortisone(DB00741)|L-Arginine(DB00125)|L-Citrulline(DB00155)	GACTCTGACTCGGGACGCCAT	0.572000													17	43					0	0	1	0	0
CCDC144A	9720	broad.mit.edu	37	17	16593944	16593944	+	Missense_Mutation	SNP	G	G	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr17:16593944G>T	ENST00000443444.2	+	1	370	c.230G>T	c.(229-231)cGc>cTc	p.R77L	CCDC144A_ENST00000399273.1_Missense_Mutation_p.R77L|RP11-219A15.1_ENST00000448331.3_Missense_Mutation_p.R77L|CCDC144A_ENST00000456009.1_Missense_Mutation_p.R77L|CCDC144A_ENST00000340621.5_Missense_Mutation_p.R77L|CCDC144A_ENST00000436374.1_3'UTR|CCDC144A_ENST00000360524.8_Missense_Mutation_p.R77L			A2RUR9	C144A_HUMAN	coiled-coil domain containing 144A	77																	CACGACGTCCGCCTGGAAGAT	0.647000													7	167					0.248553	0.248553	1	1	0
PCDH11X	27328	broad.mit.edu	37	X	91133813	91133813	+	Silent	SNP	C	C	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chrX:91133813C>T	ENST00000373094.1	+	2	3419	c.2574C>T	c.(2572-2574)aaC>aaT	p.N858N	PCDH11X_ENST00000373088.1_Silent_p.N858N|PCDH11X_ENST00000504220.2_Silent_p.N858N|PCDH11X_ENST00000361724.1_Silent_p.N858N|PCDH11X_ENST00000406881.1_Silent_p.N858N|PCDH11X_ENST00000395337.2_Silent_p.N858N|PCDH11X_ENST00000373097.1_Silent_p.N858N|PCDH11X_ENST00000361655.2_Silent_p.N858N|PCDH11X_ENST00000298274.8_Silent_p.N858N	NM_032968.3	NP_116750.1	Q9BZA7	PC11X_HUMAN	protocadherin 11 X-linked	858					homophilic cell adhesion	integral to plasma membrane	calcium ion binding			NS(1)|autonomic_ganglia(1)|biliary_tract(1)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(30)|liver(4)|lung(92)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(1)	159						CTACCCCAAACCCAGAAAACA	0.393000													31	13					0	0	1	0	0
GNGT1	2792	broad.mit.edu	37	7	93536062	93536062	+	Missense_Mutation	SNP	C	C	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr7:93536062C>A	ENST00000455502.1	+	3	258	c.4C>A	c.(4-6)Cca>Aca	p.P2T	GNGT1_ENST00000428834.1_Missense_Mutation_p.P2T|GNGT1_ENST00000248572.5_Missense_Mutation_p.P2T|GNGT1_ENST00000429473.1_Missense_Mutation_p.P2T|GNGT1_ENST00000430875.1_Missense_Mutation_p.P2T			P63211	GBG1_HUMAN	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	2					G-protein coupled receptor protein signaling pathway|synaptic transmission	heterotrimeric G-protein complex	GTPase activity|signal transducer activity			endometrium(1)|large_intestine(1)|lung(3)|prostate(1)	6	all_cancers(62;2.39e-10)|all_epithelial(64;1.54e-09)|Lung NSC(181;0.218)		STAD - Stomach adenocarcinoma(171;0.000967)			CAAAAAGATGCCAGTAATCAA	0.403000													20	66					8.00594e-06	9.02797e-06	1	1	0
EIF4G3	8672	broad.mit.edu	37	1	21329207	21329207	+	Splice_Site	SNP	G	G	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr1:21329207G>A	ENST00000602326.1	-	5	612	c.29C>T	c.(28-30)cCg>cTg	p.P10L	EIF4G3_ENST00000356916.3_Splice_Site_p.P10L|EIF4G3_ENST00000374937.3_Splice_Site_p.P10L|EIF4G3_ENST00000400422.1_Splice_Site_p.P10L|EIF4G3_ENST00000264211.8_Splice_Site_p.P10L|EIF4G3_ENST00000374935.3_Splice_Site_p.P10L|EIF4G3_ENST00000374927.4_Splice_Site_p.P10L	NM_001198802.1	NP_001185731.1	O43432	IF4G3_HUMAN	eukaryotic translation initiation factor 4 gamma, 3	10					interspecies interaction between organisms|regulation of translational initiation|RNA metabolic process	eukaryotic translation initiation factor 4F complex	protein binding|RNA cap binding|translation initiation factor activity			endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(18)|lung(20)|ovary(1)|prostate(4)|skin(3)|stomach(1)|urinary_tract(3)	70		all_lung(284;2.61e-06)|Lung NSC(340;2.81e-06)|Colorectal(325;3.46e-05)|Renal(390;9.67e-05)|Breast(348;0.00149)|Ovarian(437;0.00338)|Myeloproliferative disorder(586;0.0256)		UCEC - Uterine corpus endometrioid carcinoma (279;0.023)|COAD - Colon adenocarcinoma(152;5.42e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000327)|GBM - Glioblastoma multiforme(114;0.000696)|Kidney(64;0.0018)|STAD - Stomach adenocarcinoma(196;0.00644)|KIRC - Kidney renal clear cell carcinoma(64;0.0185)|READ - Rectum adenocarcinoma(331;0.124)|Lung(427;0.191)		CTTACTTACCGGAGAACGGGT	0.448000													13	248					0	0	1	0	0
TSSC2	0	broad.mit.edu	37	11	3427759	3427759	+	RNA	SNP	C	C	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr11:3427759C>T	ENST00000529482.1	+	0	876																											TGTCTGCACACGTCCTGCAGT	0.612000													3	48					0	0	1	0	0
KRT15	3866	broad.mit.edu	37	17	39673194	39673194	+	Missense_Mutation	SNP	G	G	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr17:39673194G>A	ENST00000254043.3	-	3	4189	c.604C>T	c.(604-606)Cgc>Tgc	p.R202C	KRT15_ENST00000393981.3_Missense_Mutation_p.R37C|KRT15_ENST00000393974.3_Missense_Mutation_p.R37C|KRT15_ENST00000393976.2_Missense_Mutation_p.R202C	NM_002275.3	NP_002266	P19012	K1C15_HUMAN	keratin 15	202	Coil 1B.|Rod.				epidermis development	intermediate filament	protein binding|structural constituent of cytoskeleton			NS(1)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(3)|lung(3)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	16		Breast(137;0.000286)				ACGCCCTGGCGCAGGGCCAGC	0.597000													4	111					0	0	1	0	0
CHEK2P2	0	broad.mit.edu	37	15	20488802	20488802	+	RNA	SNP	T	T	C			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr15:20488802T>C	ENST00000555186.1	+	0	285					NR_038836.1																						TCATGAGAACTTTATGTGGAA	0.423000													4	112					0	0	1	0	0
SPATA31A6	389730	broad.mit.edu	37	9	43627263	43627263	+	Missense_Mutation	SNP	C	C	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr9:43627263C>T	ENST00000332857.6	-	4	1452	c.1424G>A	c.(1423-1425)cGc>cAc	p.R475H		NM_001145196.1	NP_001138668.1			SPATA31 subfamily A, member 6																		AAAGGGTTGGCGGTGGGACAG	0.527000													215	332					0	0	1	0	0
ZNF814	730051	broad.mit.edu	37	19	58385546	58385546	+	Missense_Mutation	SNP	G	G	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr19:58385546G>T	ENST00000435989.2	-	3	1446	c.1212C>A	c.(1210-1212)gaC>gaA	p.D404E	ZNF814_ENST00000600634.1_Intron|ZNF814_ENST00000597342.1_Intron|ZNF814_ENST00000597832.1_Intron|ZNF814_ENST00000596604.1_Intron|ZNF814_ENST00000595295.1_Intron	NM_001144989.1	NP_001138461.1	B7Z6K7	ZN814_HUMAN	zinc finger protein 814	404					regulation of transcription, DNA-dependent	intracellular	nucleic acid binding|zinc ion binding	p.D404E(10)		NS(1)|central_nervous_system(2)|endometrium(3)|kidney(9)|lung(2)|prostate(4)|skin(1)|urinary_tract(3)	25						AATGTTTTTTGTCAGTGTGAA	0.393000													6	21					0.0215528	0.022398	1	1	0
FCGBP	8857	broad.mit.edu	37	19	40357401	40357401	+	Silent	SNP	C	C	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr19:40357401C>A	ENST00000221347.6	-	34	15919	c.15912G>T	c.(15910-15912)acG>acT	p.T5304T		NM_003890.2	NP_003881.2	Q9Y6R7	FCGBP_HUMAN	Fc fragment of IgG binding protein	5304	VWFD 13.					extracellular region	protein binding			NS(3)|autonomic_ganglia(1)|breast(7)|central_nervous_system(5)|endometrium(13)|kidney(9)|large_intestine(27)|lung(49)|ovary(8)|pancreas(3)|prostate(13)|skin(9)|stomach(9)|upper_aerodigestive_tract(6)|urinary_tract(3)	165	all_cancers(60;6.03e-06)|all_lung(34;5.58e-08)|Lung NSC(34;6.62e-08)|Ovarian(47;0.06)		Epithelial(26;6.25e-23)|all cancers(26;1.13e-20)			TTGGAGTCAACGTCACCATCC	0.542000													4	82					0.00909568	0.00964142	1	1	0
LPHN3	23284	broad.mit.edu	37	4	62812714	62812714	+	Silent	SNP	G	G	A	rs35637502		TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr4:62812714G>A	ENST00000512091.2	+	15	3045	c.2298G>A	c.(2296-2298)acG>acA	p.T766T	LPHN3_ENST00000511324.1_Silent_p.T834T|LPHN3_ENST00000506720.1_Silent_p.T834T|LPHN3_ENST00000509896.1_Silent_p.T834T|LPHN3_ENST00000506700.1_Silent_p.T766T|LPHN3_ENST00000506746.1_Silent_p.T834T|LPHN3_ENST00000514591.1_Silent_p.T766T|LPHN3_ENST00000514157.1_Silent_p.T766T|LPHN3_ENST00000514996.1_Silent_p.T766T|LPHN3_ENST00000508946.1_Silent_p.T766T|LPHN3_ENST00000507164.1_Silent_p.T834T|LPHN3_ENST00000504896.1_Silent_p.T766T|LPHN3_ENST00000508693.1_Silent_p.T834T|LPHN3_ENST00000545650.1_Silent_p.T766T|LPHN3_ENST00000508078.1_3'UTR|LPHN3_ENST00000507625.1_Silent_p.T834T			Q9HAR2	LPHN3_HUMAN	latrophilin 3						neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity|sugar binding			breast(5)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(5)|kidney(4)|large_intestine(21)|lung(73)|ovary(1)|pancreas(1)|prostate(6)|upper_aerodigestive_tract(1)	125						AGTTGGGAACGGAAGCTTTGT	0.403000													9	246					0	0	1	0	0
EFEMP1	2202	broad.mit.edu	37	2	56104979	56104979	+	Missense_Mutation	SNP	G	G	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr2:56104979G>A	ENST00000394555.2	-	6	1097	c.662C>T	c.(661-663)cCt>cTt	p.P221L	EFEMP1_ENST00000394554.1_Missense_Mutation_p.P221L|EFEMP1_ENST00000424836.2_Intron|EFEMP1_ENST00000355426.3_Missense_Mutation_p.P221L	NM_001039348.2|NM_001039349.2	NP_001034437.1|NP_001034438.1	Q12805	FBLN3_HUMAN	EGF containing fibulin-like extracellular matrix protein 1	221	EGF-like 3; calcium-binding (Potential).				negative regulation of chondrocyte differentiation|peptidyl-tyrosine phosphorylation|regulation of transcription, DNA-dependent|visual perception	extracellular space|proteinaceous extracellular matrix	calcium ion binding|epidermal growth factor receptor activity|epidermal growth factor receptor binding|growth factor activity			NS(1)|breast(2)|endometrium(4)|large_intestine(6)|lung(5)|ovary(5)|pancreas(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	28			LUSC - Lung squamous cell carcinoma(58;0.127)|Lung(47;0.132)			GCAATATGGAGGGATGGTACA	0.408000													51	115					0	0	1	0	0
PPARGC1A	10891	broad.mit.edu	37	4	23886556	23886556	+	Splice_Site	SNP	T	T	C			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr4:23886556T>C	ENST00000264867.2	-	2	174		c.e2-2		PPARGC1A_ENST00000507380.1_Splice_Site	NM_013261.3	NP_037393.1	Q9UBK2	PRGC1_HUMAN	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha						androgen receptor signaling pathway|brown fat cell differentiation|cellular glucose homeostasis|digestion|fatty acid oxidation|gluconeogenesis|mitochondrion organization|mRNA processing|neuron death|positive regulation of fatty acid oxidation|positive regulation of gluconeogenesis|positive regulation of histone acetylation|positive regulation of sequence-specific DNA binding transcription factor activity|positive regulation of transcription from RNA polymerase II promoter|protein complex assembly|protein stabilization|response to muscle activity|response to starvation|RNA splicing|temperature homeostasis|transcription initiation from RNA polymerase II promoter	DNA-directed RNA polymerase II, core complex	androgen receptor binding|DNA binding|ligand-dependent nuclear receptor binding|ligand-dependent nuclear receptor transcription coactivator activity|nucleotide binding|RNA binding|RNA polymerase II transcription cofactor activity|transcription factor binding			central_nervous_system(1)|endometrium(7)|kidney(3)|large_intestine(7)|liver(1)|lung(24)|ovary(3)|skin(5)	51		Breast(46;0.0503)				AGCAGCACACTGCAGGAGGCA	0.388000													12	32					0	0	1	0	0
ARHGEF9	23229	broad.mit.edu	37	X	62863890	62863890	+	Missense_Mutation	SNP	T	T	C			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chrX:62863890T>C	ENST00000253401.6	-	9	2139	c.1339A>G	c.(1339-1341)Atg>Gtg	p.M447V	ARHGEF9_ENST00000433323.2_Missense_Mutation_p.M174V|ARHGEF9_ENST00000374878.1_Missense_Mutation_p.M445V|ARHGEF9_ENST00000374870.4_Missense_Mutation_p.M345V|ARHGEF9_ENST00000495564.1_5'UTR|ARHGEF9_ENST00000374872.1_Missense_Mutation_p.M426V|ARHGEF9_ENST00000437457.2_Missense_Mutation_p.M394V	NM_015185.2	NP_056000.1	O43307	ARHG9_HUMAN	Cdc42 guanine nucleotide exchange factor (GEF) 9	447					apoptosis|induction of apoptosis by extracellular signals|ion transmembrane transport|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction|synaptic transmission	cytosol	Rho guanyl-nucleotide exchange factor activity			breast(1)|central_nervous_system(1)|endometrium(4)|kidney(2)|large_intestine(6)|lung(14)|ovary(5)|pancreas(1)|skin(1)	35						CTCACAGTCATTGCAGCCTGC	0.358000													4	22					0	0	1	0	0
FGF9	2254	broad.mit.edu	37	13	22246172	22246172	+	Missense_Mutation	SNP	G	G	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr13:22246172G>A	ENST00000382353.5	+	1	651	c.121G>A	c.(121-123)Gaa>Aaa	p.E41K		NM_002010.2	NP_002001.1	P31371	FGF9_HUMAN	fibroblast growth factor 9	41					cell-cell signaling|fibroblast growth factor receptor signaling pathway|insulin receptor signaling pathway|male gonad development|positive regulation of cell division	extracellular space	growth factor activity|heparin binding			breast(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(2)|skin(2)	9		all_cancers(29;1.23e-20)|all_epithelial(30;9.83e-19)|all_lung(29;9.64e-17)|Lung SC(185;0.0262)|Breast(139;0.106)		all cancers(112;3.92e-05)|Epithelial(112;0.000166)|OV - Ovarian serous cystadenocarcinoma(117;0.00314)|Lung(94;0.163)		GGGTCAGTCCGAAGCAGGGGG	0.572000													6	107					0	0	1	0	0
TRANK1	9881	broad.mit.edu	37	3	36873598	36873598	+	Silent	SNP	C	C	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr3:36873598C>A	ENST00000301807.6	-	21	7591	c.5694G>T	c.(5692-5694)ctG>ctT	p.L1898L	TRANK1_ENST00000428977.2_Silent_p.L1898L|TRANK1_ENST00000429976.2_Silent_p.L2448L			O15050	TRNK1_HUMAN	tetratricopeptide repeat and ankyrin repeat containing 1	2448					DNA repair		ATP binding|ATP-dependent DNA helicase activity|DNA binding			NS(2)|autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(18)|lung(20)|ovary(1)|prostate(3)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(2)	73						TCTTGCTAAACAGGAACTCCC	0.507000													7	119					0.00198382	0.00214576	1	1	0
SORT1	6272	broad.mit.edu	37	1	109867585	109867585	+	Missense_Mutation	SNP	T	T	G			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr1:109867585T>G	ENST00000256637.6	-	14	1828	c.1770A>C	c.(1768-1770)gaA>gaC	p.E590D	SORT1_ENST00000538502.1_Missense_Mutation_p.E453D	NM_002959.5	NP_002950.3	Q99523	SORT_HUMAN	sortilin 1	590					endocytosis|endosome to lysosome transport|endosome transport via multivesicular body sorting pathway|glucose import|Golgi to endosome transport|induction of apoptosis by extracellular signals|myotube differentiation|negative regulation of apoptosis|negative regulation of lipoprotein lipase activity|neuropeptide signaling pathway|ossification|plasma membrane to endosome transport|regulation of gene expression|response to insulin stimulus|vesicle organization	cell surface|coated pit|early endosome|endoplasmic reticulum membrane|endosome membrane|Golgi cisterna membrane|integral to membrane|lysosomal membrane|microsome|nuclear membrane|perinuclear region of cytoplasm|plasma membrane	enzyme binding|nerve growth factor binding|nerve growth factor receptor activity|neurotensin receptor activity, non-G-protein coupled			NS(1)|breast(2)|central_nervous_system(1)|endometrium(2)|kidney(2)|large_intestine(9)|lung(5)|ovary(2)|prostate(1)|skin(1)	26		all_epithelial(167;4.69e-05)|all_lung(203;0.00016)|Lung NSC(277;0.000318)|Breast(1374;0.244)		Lung(183;0.0529)|Colorectal(144;0.142)|Epithelial(280;0.145)|Kidney(133;0.169)|all cancers(265;0.184)		TCAGGAAAGATTCTGTGAAGC	0.463000													22	23					0	0	1	0	0
PAPD7	11044	broad.mit.edu	37	5	6748612	6748612	+	Nonsense_Mutation	SNP	C	C	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr5:6748612C>T	ENST00000230859.6	+	8	874	c.745C>T	c.(745-747)Cag>Tag	p.Q249*		NM_001171805.1|NM_001171806.1|NM_006999.4	NP_001165276.1|NP_001165277.1|NP_008930.1	Q5XG87	PAPD7_HUMAN	PAP associated domain containing 7	249					cell division|DNA replication|double-strand break repair|mitotic chromosome condensation|response to drug|sister chromatid cohesion	nucleus	DNA binding|DNA-directed DNA polymerase activity|metal ion binding|SMC protein binding			cervix(1)|endometrium(2)|large_intestine(8)|lung(10)|ovary(2)|pancreas(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	27						TGGCGCCATGCAGGTGAAGCA	0.542000													5	323					0	0	1	0	0
ALMS1	7840	broad.mit.edu	37	2	73646386	73646386	+	Missense_Mutation	SNP	A	A	G			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr2:73646386A>G	ENST00000264448.6	+	3	697	c.586A>G	c.(586-588)Acg>Gcg	p.T196A	ALMS1_ENST00000409009.1_Missense_Mutation_p.T154A|ALMS1_ENST00000377715.1_Missense_Mutation_p.T196A	NM_015120.4	NP_055935	Q8TCU4	ALMS1_HUMAN	Alstrom syndrome 1	196					G2/M transition of mitotic cell cycle	centrosome|cilium|cytosol|microtubule basal body|spindle pole				breast(4)|endometrium(14)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(31)|lung(68)|ovary(4)|pancreas(4)|prostate(3)|skin(8)|upper_aerodigestive_tract(1)|urinary_tract(2)	147						GGGCATATTGACGCAATCAGA	0.428000													4	80					0	0	1	0	0
FOXP2	93986	broad.mit.edu	37	7	114270018	114270018	+	Silent	SNP	G	G	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr7:114270018G>A	ENST00000393500.3	+	11	1150	c.330G>A	c.(328-330)caG>caA	p.Q110Q	FOXP2_ENST00000393498.2_Silent_p.Q165Q|FOXP2_ENST00000350908.4_Silent_p.Q185Q|FOXP2_ENST00000403559.4_Silent_p.Q202Q|FOXP2_ENST00000393494.2_Silent_p.Q185Q|FOXP2_ENST00000393491.3_Silent_p.Q93Q|FOXP2_ENST00000360232.4_Silent_p.Q185Q|FOXP2_ENST00000390668.3_Silent_p.Q209Q|FOXP2_ENST00000393489.3_Silent_p.Q93Q|FOXP2_ENST00000408937.3_Silent_p.Q210Q|FOXP2_ENST00000378237.3_Silent_p.Q185Q			O15409	FOXP2_HUMAN	forkhead box P2	185	Gln-rich.				camera-type eye development|caudate nucleus development|cerebellum development|cerebral cortex development|embryo development|growth|lung alveolus development|negative regulation of transcription, DNA-dependent|pattern specification process|positive regulation of epithelial cell proliferation involved in lung morphogenesis|positive regulation of mesenchymal cell proliferation|post-embryonic development|putamen development|regulation of sequence-specific DNA binding transcription factor activity|righting reflex|skeletal muscle tissue development|smooth muscle tissue development|vocal learning	cytoplasm|transcription factor complex	chromatin binding|DNA bending activity|double-stranded DNA binding|promoter binding|protein heterodimerization activity|protein homodimerization activity|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding|zinc ion binding	p.Q210Q(2)		breast(3)|endometrium(7)|kidney(4)|large_intestine(7)|lung(22)|ovary(4)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	52						agcagcaacagcagcagcagc	0.502000													4	79					0	0	1	0	0
TEX9	374618	broad.mit.edu	37	15	56657675	56657675	+	Splice_Site	SNP	G	G	C			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr15:56657675G>C	ENST00000561221.2	+	1	32	c.27G>C	c.(25-27)acG>acC	p.T9T	TEX9_ENST00000537232.1_5'UTR|TEX9_ENST00000558083.2_5'UTR|TEX9_ENST00000352903.2_Splice_Site_p.T9T			Q8N6V9	TEX9_HUMAN	testis expressed 9	9										cervix(1)|kidney(1)|large_intestine(4)|lung(6)|prostate(1)|skin(1)	14				all cancers(107;0.0394)|GBM - Glioblastoma multiforme(80;0.056)		TGTGTCTCACGGTCAGTTCAA	0.587000													11	43					0	0	1	0	0
MUC5AC	4586	broad.mit.edu	37	11	1157545	1157545	+	Missense_Mutation	SNP	C	C	T			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr11:1157545C>T	ENST00000356191.2	+	12	716	c.716C>T	c.(715-717)aCg>aTg	p.T239M						mucin 5AC, oligomeric mucus/gel-forming											NS(1)|breast(2)|central_nervous_system(7)|cervix(2)|endometrium(36)|haematopoietic_and_lymphoid_tissue(5)|kidney(9)|large_intestine(19)|liver(1)|lung(89)|ovary(7)|prostate(8)|skin(9)|stomach(1)|upper_aerodigestive_tract(6)|urinary_tract(1)	203		all_cancers(49;2.94e-05)|Breast(177;0.00257)|all_epithelial(84;0.00314)|Ovarian(85;0.0228)|Medulloblastoma(188;0.0321)|all_neural(188;0.0762)		BRCA - Breast invasive adenocarcinoma(625;0.00146)|Lung(200;0.0612)|LUSC - Lung squamous cell carcinoma(625;0.0724)		AGAAGATGGACGACCCCACGG	0.627000													5	25					0	0	1	0	0
AOAH	313	broad.mit.edu	37	7	36561718	36561718	+	Missense_Mutation	SNP	A	A	G			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr7:36561718A>G	ENST00000431169.1	-	20	1826	c.1526T>C	c.(1525-1527)aTa>aCa	p.I509T	AOAH_ENST00000538464.1_Missense_Mutation_p.I231T|AOAH_ENST00000535891.1_Missense_Mutation_p.I477T|AOAH_ENST00000258749.5_Missense_Mutation_p.I509T	NM_001177506.1	NP_001170977.1	P28039	AOAH_HUMAN	acyloxyacyl hydrolase (neutrophil)	509					inflammatory response|lipid metabolic process	extracellular region	acyloxyacyl hydrolase activity|lipoprotein lipase activity			NS(1)|autonomic_ganglia(1)|breast(2)|cervix(1)|endometrium(2)|large_intestine(3)|lung(21)|prostate(5)|skin(1)|stomach(1)|urinary_tract(3)	41						CCACTCCTGTATGACTGCAGG	0.582000													5	52					0	0	1	0	0
TMEM171	134285	broad.mit.edu	37	5	72419573	72419573	+	Missense_Mutation	SNP	C	C	G			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr5:72419573C>G	ENST00000454765.2	+	2	846	c.373C>G	c.(373-375)Ctc>Gtc	p.L125V	TMEM171_ENST00000287773.5_Missense_Mutation_p.L125V			Q8WVE6	TM171_HUMAN	transmembrane protein 171	125						integral to membrane				endometrium(5)|kidney(2)|large_intestine(2)|lung(4)|prostate(1)|stomach(1)	15		Lung NSC(167;0.0378)|Ovarian(174;0.0908)|Prostate(461;0.165)		OV - Ovarian serous cystadenocarcinoma(47;1.87e-54)|Lung(70;0.115)		AAGCGGCATGCTCATCAGCGT	0.587000													6	122					0	0	1	0	0
AC093838.4	0	broad.mit.edu	37	2	132275379	132275379	+	RNA	SNP	C	C	G	rs142886923	by1000genomes	TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr2:132275379C>G	ENST00000438378.2	+	0	1652					NR_026922.1																						CCGCACAGACCTGGTTAGCCC	0.582000													19	32					0	0	1	0	0
ABLIM1	3983	broad.mit.edu	37	10	116207677	116207677	+	Missense_Mutation	SNP	G	G	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr10:116207677G>A	ENST00000369252.4	-	15	1818	c.1517C>T	c.(1516-1518)aCg>aTg	p.T506M	ABLIM1_ENST00000277895.5_Missense_Mutation_p.T566M|ABLIM1_ENST00000369253.2_Missense_Mutation_p.T189M|ABLIM1_ENST00000392952.3_Missense_Mutation_p.T243M|ABLIM1_ENST00000369266.3_Missense_Mutation_p.T243M|ABLIM1_ENST00000533213.2_Missense_Mutation_p.T506M	NM_001003407.1|NM_001003408.1	NP_001003407.1|NP_001003408.1	O14639	ABLM1_HUMAN	actin binding LIM protein 1	566					axon guidance|cytoskeleton organization|organ morphogenesis|visual perception	actin cytoskeleton|cytoplasm	actin binding|zinc ion binding			breast(3)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(6)|lung(11)|prostate(2)|skin(2)|stomach(1)|urinary_tract(1)	30		Colorectal(252;0.0373)|Breast(234;0.231)		Epithelial(162;0.0132)|all cancers(201;0.0383)		CCAGTGGTCCGTCTCAATCTT	0.542000													27	60					0	0	1	0	0
RBM44	375316	broad.mit.edu	37	2	238737984	238737984	+	Missense_Mutation	SNP	T	T	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr2:238737984T>A	ENST00000316997.4	+	13	2860	c.2728T>A	c.(2728-2730)Tca>Aca	p.S910T	RBM44_ENST00000409864.1_Missense_Mutation_p.S910T	NM_001080504.2	NP_001073973.2	Q6ZP01	RBM44_HUMAN	RNA binding motif protein 44	909							nucleotide binding|RNA binding			breast(1)|endometrium(4)|kidney(4)|large_intestine(11)|lung(7)|ovary(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	33		Breast(86;0.0042)|Renal(207;0.00571)|Ovarian(221;0.17)|all_hematologic(139;0.182)		Epithelial(121;3.74e-22)|OV - Ovarian serous cystadenocarcinoma(60;5.3e-11)|Kidney(56;3.04e-09)|KIRC - Kidney renal clear cell carcinoma(57;6.5e-08)|BRCA - Breast invasive adenocarcinoma(100;0.000118)|Lung(119;0.0112)|LUSC - Lung squamous cell carcinoma(224;0.0266)		AGAATATACATCACCACTTTC	0.348000													7	53					0	0	1	0	0
GRIA1	0	broad.mit.edu	37	5	153144159	153144159	+	Silent	SNP	G	G	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr5:153144159G>A	ENST00000285900.5	+	12	2332	c.1989G>A	c.(1987-1989)acG>acA	p.T663T	GRIA1_ENST00000340592.5_Silent_p.T663T|GRIA1_ENST00000448073.4_Silent_p.T673T|GRIA1_ENST00000518142.1_Silent_p.T583T|GRIA1_ENST00000518783.1_Silent_p.T673T|GRIA1_ENST00000521843.2_Silent_p.T594T	NM_000827.3|NM_001258019.1	NP_000818.2|NP_001244948.1	P42261	GRIA1_HUMAN	glutamate receptor, ionotropic, AMPA 1	663					synaptic transmission	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|cell junction|dendritic spine|endocytic vesicle membrane|endoplasmic reticulum membrane|neuronal cell body|postsynaptic density|postsynaptic membrane	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity|extracellular-glutamate-gated ion channel activity|kainate selective glutamate receptor activity|PDZ domain binding			NS(1)|breast(4)|endometrium(7)|kidney(3)|large_intestine(24)|liver(2)|lung(23)|ovary(4)|pancreas(1)|prostate(5)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(2)	81		Medulloblastoma(196;0.0391)|all_neural(177;0.16)|all_hematologic(541;0.21)	Kidney(363;0.000173)|KIRC - Kidney renal clear cell carcinoma(527;0.000785)		Desflurane(DB01189)|Enflurane(DB00228)|Halothane(DB01159)|Isoflurane(DB00753)|L-Glutamic Acid(DB00142)|Methoxyflurane(DB01028)|Sevoflurane(DB01236)	CCTACGGGACGCTGGAAGCAG	0.502000													18	41					0	0	1	0	0
FAM111A	63901	broad.mit.edu	37	11	58920765	58920765	+	Missense_Mutation	SNP	G	G	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr11:58920765G>A	ENST00000528737.1	+	5	4442	c.1624G>A	c.(1624-1626)Ggc>Agc	p.G542S	FAM111A_ENST00000420244.1_Missense_Mutation_p.G542S|FAM111A_ENST00000361723.3_Missense_Mutation_p.G542S|FAM111A_ENST00000531147.1_Missense_Mutation_p.G542S|FAM111A_ENST00000533703.1_Missense_Mutation_p.G542S			Q96PZ2	F111A_HUMAN	family with sequence similarity 111, member A	542					proteolysis		serine-type endopeptidase activity			breast(2)|endometrium(2)|kidney(1)|large_intestine(5)|lung(5)|ovary(3)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	22		all_epithelial(135;0.139)				TGGGGCTTCCGGCTCCCCTGT	0.413000													4	148					0	0	1	0	0
FOXP2	93986	broad.mit.edu	37	7	114270000	114270000	+	Silent	SNP	G	G	A			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr7:114270000G>A	ENST00000393500.3	+	11	1132	c.312G>A	c.(310-312)caG>caA	p.Q104Q	FOXP2_ENST00000393498.2_Silent_p.Q159Q|FOXP2_ENST00000350908.4_Silent_p.Q179Q|FOXP2_ENST00000403559.4_Silent_p.Q196Q|FOXP2_ENST00000393494.2_Silent_p.Q179Q|FOXP2_ENST00000393491.3_Silent_p.Q87Q|FOXP2_ENST00000360232.4_Silent_p.Q179Q|FOXP2_ENST00000390668.3_Silent_p.Q203Q|AC020606.1_ENST00000580664.1_RNA|FOXP2_ENST00000393489.3_Silent_p.Q87Q|FOXP2_ENST00000408937.3_Silent_p.Q204Q|FOXP2_ENST00000378237.3_Silent_p.Q179Q			O15409	FOXP2_HUMAN	forkhead box P2	179	Gln-rich.				camera-type eye development|caudate nucleus development|cerebellum development|cerebral cortex development|embryo development|growth|lung alveolus development|negative regulation of transcription, DNA-dependent|pattern specification process|positive regulation of epithelial cell proliferation involved in lung morphogenesis|positive regulation of mesenchymal cell proliferation|post-embryonic development|putamen development|regulation of sequence-specific DNA binding transcription factor activity|righting reflex|skeletal muscle tissue development|smooth muscle tissue development|vocal learning	cytoplasm|transcription factor complex	chromatin binding|DNA bending activity|double-stranded DNA binding|promoter binding|protein heterodimerization activity|protein homodimerization activity|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding|zinc ion binding	p.Q204Q(1)		breast(3)|endometrium(7)|kidney(4)|large_intestine(7)|lung(22)|ovary(4)|pancreas(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	52						agcaacaacagcagcagcagc	0.498000													4	70					0	0	1	0	0
ATP6V1C2	245973	broad.mit.edu	37	2	10917819	10917820	+	Frame_Shift_Del	DEL	AG	AG	-			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr2:10917819_10917820delAG	ENST00000272238.4	+	11	1043_1044	c.934_935delAG	c.(934-936)agafs	p.R312fs	ATP6V1C2_ENST00000381661.3_Intron	NM_001039362.1	NP_001034451.1	Q8NEY4	VATC2_HUMAN	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2	312					ATP hydrolysis coupled proton transport|cellular iron ion homeostasis|insulin receptor signaling pathway|transferrin transport	cytosol|proton-transporting V-type ATPase, V1 domain				endometrium(2)|kidney(1)|large_intestine(3)|lung(8)|ovary(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	19	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.191)			Epithelial(75;0.15)|OV - Ovarian serous cystadenocarcinoma(76;0.152)		GCAGACCGACAGAGAGAGAGAG	0.604													8	110	---	---	---	---					
FAM53A	152877	broad.mit.edu	37	4	1657001	1657001	+	Frame_Shift_Del	DEL	C	C	-			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr4:1657001delC	ENST00000308132.6	-	4	778	c.586delG	c.(586-588)gacfs	p.D196fs	FAM53A_ENST00000461064.1_Frame_Shift_Del_p.D196fs|FAM53A_ENST00000489363.1_Frame_Shift_Del_p.D196fs|FAM53A_ENST00000472884.2_Frame_Shift_Del_p.D196fs	NM_001174070.1	NP_001167541.1	Q6NSI3	FA53A_HUMAN	family with sequence similarity 53, member A	196						nucleus				breast(2)|central_nervous_system(2)|large_intestine(1)|lung(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	10		all_epithelial(65;0.206)|Breast(71;0.212)	OV - Ovarian serous cystadenocarcinoma(23;0.0145)			TCGCTGCTGTCCACGAAGCCG	0.746													2	4	---	---	---	---					
MSH5-SAPCD1	0	broad.mit.edu	37	6	31709057	31709058	+	Frame_Shift_Ins	INS	-	-	AG			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr6:31709057_31709058insAG	ENST00000493662.2	+	3	321_322	c.265_266insAG	c.(265-267)cagfs	p.Q89fs	MSH5_ENST00000534153.4_Frame_Shift_Ins_p.Q89fs|MSH5_ENST00000375750.3_Frame_Shift_Ins_p.Q89fs|MSH5_ENST00000375755.3_Frame_Shift_Ins_p.Q89fs|MSH5_ENST00000375742.3_Frame_Shift_Ins_p.Q89fs|MSH5_ENST00000375740.3_Frame_Shift_Ins_p.Q89fs|MSH5_ENST00000375703.3_Frame_Shift_Ins_p.Q89fs|MSH5_ENST00000482280.1_3'UTR																							CAAGCTTCTCCAGAGAGGTGGG	0.500													28	125	---	---	---	---					
CHST15	51363	broad.mit.edu	37	10	125780846	125780852	+	Frame_Shift_Del	DEL	GCTGCAG	GCTGCAG	-			TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr10:125780846_125780852delGCTGCAG	ENST00000346248.5	-	6	1909_1915	c.1267_1273delCTGCAGC	c.(1267-1275)ctgcagctgfs	p.LQL423fs	CHST15_ENST00000421115.1_Frame_Shift_Del_p.LQL423fs|CHST15_ENST00000435907.1_Frame_Shift_Del_p.LQL423fs	NM_015892.4	NP_056976.2	Q7LFX5	CHSTF_HUMAN	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15	423					hexose biosynthetic process	Golgi membrane|integral to membrane	3'-phosphoadenosine 5'-phosphosulfate binding|N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity			endometrium(4)|kidney(1)|large_intestine(11)|lung(6)|ovary(3)|stomach(1)	26						TTTTCAAACAGCTGCAGTGCTTCTGTC	0.473													12	24	---	---	---	---					
BAIAP2L2	80115	broad.mit.edu	37	22	38482353	38482394	+	In_Frame_Del	DEL	TGCGGGAGCGGGACTGGCCATCCCAGTACTCCGAGGGTGCTA	TGCGGGAGCGGGACTGGCCATCCCAGTACTCCGAGGGTGCTA	-	rs113792005	by1000genomes	TCGA-J4-A67N-01A-11D-A30E-08	TCGA-J4-A67N-10A-01D-A30H-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f07d2982-6313-4e21-a0a1-cf713daff114	f73b4226-3788-4704-acae-67420da417dd	g.chr22:38482353_38482394delTGCGGGAGCGGGACTGGCCATCCCAGTACTCCGAGGGTGCTA	ENST00000381669.3	-	12	1466_1507	c.1322_1363delTAGCACCCTCGGAGTACTGGGATGGCCAGTCCCGCTCCCGCA	c.(1321-1365)atagcaccctcggagtactgggatggccagtcccgctcccgcacc>acc	p.IAPSEYWDGQSRSR441del		NM_025045.4	NP_079321.3	Q6UXY1	BI2L2_HUMAN	BAI1-associated protein 2-like 2	441					filopodium assembly|signal transduction		cytoskeletal adaptor activity|SH3 domain binding			large_intestine(2)|lung(1)|ovary(2)|pancreas(1)|prostate(1)|stomach(1)	8	Melanoma(58;0.045)					CGGCTTGGGGTGCGGGAGCGGGACTGGCCATCCCAGTACTCCGAGGGTGCTATGGAGTTGCC	0.674													4	6	---	---	---	---					
