Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
SSX2IP	117178	broad.mit.edu	37	1	85116179	85116179	+	Silent	SNP	C	C	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr1:85116179C>T	ENST00000437941.2	-	12	1807	c.1455G>A	c.(1453-1455)tcG>tcA	p.S485S	SSX2IP_ENST00000605755.1_Silent_p.S485S|SSX2IP_ENST00000342203.3_Silent_p.S512S|SSX2IP_ENST00000370612.4_Silent_p.S512S|SSX2IP_ENST00000603677.1_Silent_p.S31S	NM_001166295.1|NM_001166417.1	NP_001159767.1|NP_001159889.1	Q9Y2D8	ADIP_HUMAN	synovial sarcoma, X breakpoint 2 interacting protein	512					cell adhesion	nucleus|protein complex				endometrium(5)|kidney(1)|large_intestine(4)|lung(6)|ovary(2)|urinary_tract(1)	19				all cancers(265;0.0053)|Epithelial(280;0.0214)|OV - Ovarian serous cystadenocarcinoma(397;0.173)		GCGGCTGCCTCGAGTGCACTA	0.413000													7	149					0	0	1	0	0
ZNF763	284390	broad.mit.edu	37	19	12089838	12089838	+	Missense_Mutation	SNP	C	C	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr19:12089838C>T	ENST00000343949.5	+	4	1263	c.1108C>T	c.(1108-1110)Cct>Tct	p.P370S	ZNF763_ENST00000358987.3_Missense_Mutation_p.P367S|ZNF763_ENST00000590798.1_Missense_Mutation_p.P387S|ZNF763_ENST00000545530.1_Missense_Mutation_p.P245S|ZNF763_ENST00000538752.1_Missense_Mutation_p.P387S	NM_001012753.1	NP_001012771.1			zinc finger protein 763											central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(9)	15						TGCGAAAAAACCTTATGAATG	0.398000													52	81					0	0	1	0	0
SIRPA	140885	broad.mit.edu	37	20	1903277	1903277	+	Missense_Mutation	SNP	C	C	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr20:1903277C>T	ENST00000358771.4	+	4	1225	c.1073C>T	c.(1072-1074)tCa>tTa	p.S358L	SIRPA_ENST00000400068.3_Missense_Mutation_p.S358L|SIRPA_ENST00000356025.3_Missense_Mutation_p.S358L	NM_001040023.1	NP_001035112.1	P78324	SHPS1_HUMAN	signal-regulatory protein alpha	358					blood coagulation|cell adhesion|cell junction assembly|leukocyte migration	integral to membrane|plasma membrane	SH3 domain binding			cervix(1)|endometrium(1)|kidney(1)|large_intestine(2)|lung(13)|ovary(1)|pancreas(1)|upper_aerodigestive_tract(1)	21				Colorectal(46;0.018)|READ - Rectum adenocarcinoma(1;0.0556)		GAGCAGGGCTCAAATACCGCC	0.488000													4	13					0	0	1	0	0
UBBP4	0	broad.mit.edu	37	17	21731270	21731270	+	Missense_Mutation	SNP	T	T	C			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr17:21731270T>C	ENST00000584755.1	+	2	969	c.572T>C	c.(571-573)aTc>aCc	p.I191T	UBBP4_ENST00000578713.1_Intron|UBBP4_ENST00000583708.1_3'UTR														p.I191T(3)		endometrium(9)|kidney(4)|lung(4)|prostate(3)|urinary_tract(4)	24						ATCCCCCCGATCAGCAGAGGC	0.547000													4	88					0	0	1	0	0
TFDP3	51270	broad.mit.edu	37	X	132351178	132351178	+	Silent	SNP	G	G	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chrX:132351178G>A	ENST00000310125.4	-	1	1198	c.1110C>T	c.(1108-1110)tcC>tcT	p.S370S		NM_016521.2	NP_057605.3	Q5H9I0	TFDP3_HUMAN	transcription factor Dp family, member 3	370						transcription factor complex	DNA binding|sequence-specific DNA binding transcription factor activity			breast(1)|endometrium(2)|kidney(4)|large_intestine(1)|lung(8)|ovary(1)|prostate(2)	19	Acute lymphoblastic leukemia(192;0.000127)					GAGATCCACCGGAGCTTGTGG	0.572000													4	69					0	0	1	0	0
USP54	159195	broad.mit.edu	37	10	75289357	75289357	+	Missense_Mutation	SNP	C	C	G			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr10:75289357C>G	ENST00000319786.7	-	15	2984	c.2141G>C	c.(2140-2142)aGa>aCa	p.R714T	USP54_ENST00000428547.1_Intron|USP54_ENST00000408019.1_Intron|USP54_ENST00000339859.4_Intron|USP54_ENST00000497106.1_Intron|USP54_ENST00000394811.2_Intron			Q70EL1	UBP54_HUMAN	ubiquitin specific peptidase 54	0					ubiquitin-dependent protein catabolic process		protein binding|ubiquitin thiolesterase activity			breast(5)|cervix(1)|endometrium(3)|kidney(2)|large_intestine(5)|lung(12)|ovary(1)|prostate(1)	30	Prostate(51;0.0112)					CTCCACTTGTCTCAGCCATGC	0.473000											OREG0020266	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	32					0	0	1	0	0
KCNA10	3744	broad.mit.edu	37	1	111060344	111060344	+	Missense_Mutation	SNP	G	G	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr1:111060344G>A	ENST00000369771.2	-	1	1453	c.1066C>T	c.(1066-1068)Cgc>Tgc	p.R356C		NM_005549.2	NP_005540.1	Q16322	KCA10_HUMAN	potassium voltage-gated channel, shaker-related subfamily, member 10	356						voltage-gated potassium channel complex	intracellular cyclic nucleotide activated cation channel activity|voltage-gated potassium channel activity	p.R356C(1)		endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(13)|lung(13)|ovary(3)|skin(1)|urinary_tract(1)	35		all_cancers(81;4.57e-06)|all_epithelial(167;1.52e-05)|all_lung(203;0.000152)|Lung NSC(277;0.000301)		Lung(183;0.0238)|all cancers(265;0.0874)|Colorectal(144;0.103)|Epithelial(280;0.116)|LUSC - Lung squamous cell carcinoma(189;0.134)		TTGGAGTGGCGCGAGAGCTTG	0.572000													9	98					0	0	1	0	0
CNNM2	54805	broad.mit.edu	37	10	104678735	104678735	+	Missense_Mutation	SNP	C	C	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr10:104678735C>A	ENST00000369878.4	+	1	686	c.498C>A	c.(496-498)aaC>aaA	p.N166K	CNNM2_ENST00000369875.3_Missense_Mutation_p.N166K|CNNM2_ENST00000433628.2_Missense_Mutation_p.N166K	NM_017649.4	NP_060119.3	Q9H8M5	CNNM2_HUMAN	cyclin M2						ion transport	integral to membrane				central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(5)|lung(7)|ovary(1)|prostate(2)|urinary_tract(1)	19		Colorectal(252;0.103)|all_hematologic(284;0.152)|Breast(234;0.198)		Epithelial(162;7.89e-09)|all cancers(201;1.82e-07)|BRCA - Breast invasive adenocarcinoma(275;0.215)		TCATTCTCAACCGCCGCACCT	0.647000													8	165					5.18039e-06	5.77244e-06	1	1	0
LRP1B	53353	broad.mit.edu	37	2	141253252	141253252	+	Silent	SNP	G	G	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr2:141253252G>A	ENST00000389484.3	-	56	9887	c.8916C>T	c.(8914-8916)tgC>tgT	p.C2972C		NM_018557.2	NP_061027.2	Q9NZR2	LRP1B_HUMAN	low density lipoprotein receptor-related protein 1B	2972	EGF-like 7.				protein transport|receptor-mediated endocytosis	integral to membrane	calcium ion binding			NS(5)|autonomic_ganglia(1)|biliary_tract(1)|breast(3)|central_nervous_system(7)|endometrium(25)|haematopoietic_and_lymphoid_tissue(10)|kidney(27)|large_intestine(98)|liver(4)|lung(337)|ovary(15)|pancreas(6)|prostate(11)|skin(30)|stomach(2)|upper_aerodigestive_tract(19)|urinary_tract(5)	606		all_cancers(3;1.1e-60)|all_epithelial(3;1.94e-59)|all_lung(3;1.09e-24)|Lung NSC(3;5.65e-24)|Esophageal squamous(3;5.41e-13)|Renal(3;0.000147)|Breast(3;0.000527)|Hepatocellular(3;0.011)|all_neural(3;0.014)|Colorectal(150;0.101)		UCEC - Uterine corpus endometrioid carcinoma (2;0.00139)|Epithelial(1;1.25e-24)|all cancers(1;8.86e-24)|OV - Ovarian serous cystadenocarcinoma(1;2.45e-12)|LUSC - Lung squamous cell carcinoma(1;2.97e-10)|Lung(1;6.05e-09)|BRCA - Breast invasive adenocarcinoma(221;0.0103)		AGCCTGAAGAGCATTCATCAA	0.418000										TSP Lung(27;0.18)			9	46					0	0	1	0	0
HERC2P3	0	broad.mit.edu	37	15	20644447	20644447	+	RNA	SNP	T	T	G			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr15:20644447T>G	ENST00000428453.1	-	0	3187																				central_nervous_system(1)|endometrium(11)|kidney(2)|large_intestine(1)|lung(14)|pancreas(1)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	35						AGACGGCCACTCACCTCTGAG	0.637000													8	9					0	0	1	0	0
KNDC1	85442	broad.mit.edu	37	10	135024980	135024980	+	Silent	SNP	C	C	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr10:135024980C>T	ENST00000304613.3	+	22	3984	c.3963C>T	c.(3961-3963)tgC>tgT	p.C1321C	KNDC1_ENST00000368572.2_Silent_p.C1323C			Q76NI1	VKIND_HUMAN	kinase non-catalytic C-lobe domain (KIND) containing 1	1321	N-terminal Ras-GEF.				regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction					NS(4)|breast(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(6)|lung(27)|ovary(1)|prostate(5)|skin(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	60		all_cancers(35;4.16e-10)|all_epithelial(44;2.07e-08)|Lung NSC(174;0.000845)|all_lung(145;0.00145)|all_neural(114;0.0299)|Melanoma(40;0.123)|Colorectal(31;0.173)|Glioma(114;0.203)		OV - Ovarian serous cystadenocarcinoma(35;8.77e-06)|Epithelial(32;1.13e-05)|all cancers(32;1.51e-05)		GGAGCCTCTGCGTCCTGCAGG	0.642000													27	45					0	0	1	0	0
CDC27	996	broad.mit.edu	37	17	45219653	45219653	+	Silent	SNP	C	C	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr17:45219653C>T	ENST00000066544.3	-	11	1413	c.1320G>A	c.(1318-1320)ggG>ggA	p.G440G	CDC27_ENST00000531206.1_Silent_p.G446G|CDC27_ENST00000527547.1_Silent_p.G440G|CDC27_ENST00000446365.2_Silent_p.G379G	NM_001114091.1|NM_001256.3	NP_001107563.1|NP_001247.3	P30260	CDC27_HUMAN	cell division cycle 27	440					anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell proliferation|mitotic cell cycle spindle assembly checkpoint|mitotic metaphase/anaphase transition|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|protein K11-linked ubiquitination	anaphase-promoting complex|centrosome|cytosol|nucleoplasm|spindle microtubule	protein phosphatase binding			NS(1)|breast(5)|central_nervous_system(3)|cervix(1)|endometrium(2)|kidney(17)|large_intestine(18)|lung(11)|ovary(5)|pancreas(1)|prostate(19)|skin(5)|upper_aerodigestive_tract(2)	90						TGGATATTTTCCCTTCTGAAA	0.313000													3	22					0	0	1	0	0
KCNH3	23416	broad.mit.edu	37	12	49934916	49934916	+	Splice_Site	SNP	G	G	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr12:49934916G>T	ENST00000257981.6	+	2	570		c.e2+1		KCNH3_ENST00000550434.1_Splice_Site	NM_012284.1	NP_036416.1	Q9ULD8	KCNH3_HUMAN	potassium voltage-gated channel, subfamily H (eag-related), member 3						regulation of transcription, DNA-dependent	integral to membrane	two-component sensor activity|voltage-gated potassium channel activity			NS(2)|central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(5)|lung(20)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	36						CGGAAGAGCGGTGAGGGGCCA	0.617000													8	11					0.00307968	0.00333632	1	1	0
LAMA3	3909	broad.mit.edu	37	18	21484015	21484015	+	Missense_Mutation	SNP	C	C	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr18:21484015C>T	ENST00000313654.9	+	50	6678	c.6437C>T	c.(6436-6438)gCg>gTg	p.A2146V	LAMA3_ENST00000399516.3_Missense_Mutation_p.A2090V|LAMA3_ENST00000269217.6_Missense_Mutation_p.A537V|LAMA3_ENST00000588770.1_3'UTR|LAMA3_ENST00000587184.1_Missense_Mutation_p.A481V	NM_198129.1	NP_937762.1	Q16787	LAMA3_HUMAN	laminin, alpha 3	2146	Domain II and I.				cell adhesion|epidermis development|hemidesmosome assembly|regulation of cell adhesion|regulation of cell migration|regulation of embryonic development	laminin-1 complex	receptor binding|structural molecule activity			NS(2)|breast(4)|central_nervous_system(3)|cervix(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(24)|lung(54)|ovary(8)|prostate(6)|skin(7)|urinary_tract(4)	128	all_cancers(21;7.81e-05)|all_epithelial(16;4.45e-07)|Lung NSC(20;0.00156)|all_lung(20;0.00508)|Colorectal(14;0.0202)|Ovarian(20;0.17)				Alteplase(DB00009)|Anistreplase(DB00029)|Reteplase(DB00015)|Tenecteplase(DB00031)	GAAAAGCACGCGCGGTCCTTA	0.522000													7	88					0	0	1	0	0
CALCOCO1	57658	broad.mit.edu	37	12	54108441	54108441	+	Missense_Mutation	SNP	G	G	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr12:54108441G>T	ENST00000548263.1	-	11	1471	c.1423C>A	c.(1423-1425)Ctg>Atg	p.L475M	CALCOCO1_ENST00000550804.1_Missense_Mutation_p.L475M|CALCOCO1_ENST00000262059.4_Missense_Mutation_p.L475M|CALCOCO1_ENST00000430117.2_Missense_Mutation_p.L390M			Q9P1Z2	CACO1_HUMAN	calcium binding and coiled-coil domain 1	475					steroid hormone receptor signaling pathway|transcription, DNA-dependent|Wnt receptor signaling pathway	cytoplasm	armadillo repeat domain binding|beta-catenin binding|ligand-dependent nuclear receptor transcription coactivator activity|protein C-terminus binding|sequence-specific DNA binding|transcription regulatory region DNA binding			NS(2)|breast(1)|endometrium(3)|kidney(1)|large_intestine(4)|lung(14)|ovary(1)|stomach(1)|upper_aerodigestive_tract(1)	28						GCTGACCGCAGCTCTGTCAGC	0.562000													4	30					0.150653	0.150653	1	1	0
CHST11	50515	broad.mit.edu	37	12	105150943	105150943	+	Missense_Mutation	SNP	C	C	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr12:105150943C>T	ENST00000303694.5	+	3	860	c.421C>T	c.(421-423)Cgg>Tgg	p.R141W	CHST11_ENST00000549260.1_Missense_Mutation_p.R136W	NM_018413.5	NP_060883.1	Q9NPF2	CHSTB_HUMAN	carbohydrate (chondroitin 4) sulfotransferase 11	141					chondroitin sulfate biosynthetic process	Golgi membrane|integral to membrane	chondroitin 4-sulfotransferase activity|N-acetylgalactosamine 4-O-sulfotransferase activity			breast(2)|endometrium(2)|large_intestine(4)|lung(6)|ovary(1)|prostate(2)|skin(1)	18						CCTGACCGGGCGGGGGAAGTA	0.597000													6	51					0	0	1	0	0
RPL10	6134	broad.mit.edu	37	X	153628938	153628938	+	Missense_Mutation	SNP	G	G	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chrX:153628938G>A	ENST00000424325.2	+	6	651	c.463G>A	c.(463-465)Gcc>Acc	p.A155T	RPL10_ENST00000369817.2_Missense_Mutation_p.A155T|RPL10_ENST00000406022.2_Missense_Mutation_p.A104T	NM_001256577.1|NM_001256580.1|NM_006013.3	NP_001243506.1|NP_001243509.1|NP_006004.2	P27635	RL10_HUMAN	ribosomal protein L10	155					endocrine pancreas development|translational elongation|translational termination|viral transcription	cytosolic large ribosomal subunit|endoplasmic reticulum	structural constituent of ribosome			large_intestine(1)|lung(4)|ovary(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	8	all_cancers(53;3.7e-16)|all_epithelial(53;2.97e-10)|all_lung(58;1.84e-07)|Lung NSC(58;5.84e-07)|all_hematologic(71;2.45e-06)|Acute lymphoblastic leukemia(192;6.56e-05)|Breast(217;0.176)					CCTGCGCAGGGCCAAGTTCAA	0.582000													3	42					0	0	1	0	0
OR6Y1	391112	broad.mit.edu	37	1	158517850	158517850	+	Missense_Mutation	SNP	G	G	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr1:158517850G>A	ENST00000302617.3	-	1	45	c.46C>T	c.(46-48)Cgt>Tgt	p.R16C		NM_001005189.1	NP_001005189.1	Q8NGX8	OR6Y1_HUMAN	olfactory receptor, family 6, subfamily Y, member 1	16					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(1)|kidney(1)|large_intestine(5)|lung(16)|ovary(1)|prostate(2)|upper_aerodigestive_tract(2)|urinary_tract(2)	30	all_hematologic(112;0.0378)					AGAATGAAACGTGTTGTCACT	0.458000													17	38					0	0	1	0	0
TRRAP	8295	broad.mit.edu	37	7	98513418	98513418	+	Silent	SNP	T	T	C			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr7:98513418T>C	ENST00000359863.4	+	19	2481	c.2272T>C	c.(2272-2274)Ttg>Ctg	p.L758L	TRRAP_ENST00000355540.3_Silent_p.L758L|TRRAP_ENST00000446306.3_Silent_p.L757L	NM_001244580.1	NP_001231509.1	Q9Y4A5	TRRAP_HUMAN	transformation/transcription domain-associated protein	758					histone deubiquitination|histone H2A acetylation|histone H4 acetylation|regulation of transcription, DNA-dependent|transcription, DNA-dependent	NuA4 histone acetyltransferase complex|PCAF complex|STAGA complex|transcription factor TFTC complex	phosphotransferase activity, alcohol group as acceptor|protein binding|transcription cofactor activity			NS(3)|breast(1)|central_nervous_system(10)|endometrium(16)|kidney(7)|large_intestine(36)|liver(1)|lung(54)|ovary(10)|pancreas(1)|prostate(8)|skin(16)|stomach(5)|upper_aerodigestive_tract(6)|urinary_tract(2)	176	all_cancers(62;6.96e-09)|all_epithelial(64;4.86e-09)|Lung NSC(181;0.01)|all_lung(186;0.016)|Esophageal squamous(72;0.0274)		STAD - Stomach adenocarcinoma(171;0.215)			CAACTACTTCTTGCTGCTACG	0.532000													4	83					0	0	1	0	0
PEAR1	375033	broad.mit.edu	37	1	156883723	156883723	+	Silent	SNP	G	G	T	rs150673528		TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr1:156883723G>T	ENST00000338302.3	+	23	3018	c.2793G>T	c.(2791-2793)ctG>ctT	p.L931L	PEAR1_ENST00000292357.7_Silent_p.L931L			Q5VY43	PEAR1_HUMAN	platelet endothelial aggregation receptor 1	931	Pro-rich.					integral to membrane				breast(1)|central_nervous_system(2)|endometrium(4)|large_intestine(6)|lung(22)|ovary(4)|skin(3)|upper_aerodigestive_tract(1)	43	all_hematologic(923;0.0839)|Hepatocellular(266;0.158)					TCCGGGACCTGCCCAGCTTGC	0.617000													3	20					0.115264	0.118297	1	1	0
TUSC5	286753	broad.mit.edu	37	17	1183349	1183349	+	Silent	SNP	C	C	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr17:1183349C>T	ENST00000333813.3	+	1	393	c.54C>T	c.(52-54)gcC>gcT	p.A18A		NM_172367.2	NP_758955.2	Q8IXB3	TUSC5_HUMAN	tumor suppressor candidate 5	18			A -> T.		response to biotic stimulus	integral to membrane				endometrium(2)|kidney(2)|large_intestine(3)|lung(2)|prostate(4)|skin(2)	15				UCEC - Uterine corpus endometrioid carcinoma (25;0.0822)		CAGGCTCCGCCGCATTCCTGG	0.642000													9	65					0	0	1	0	0
HSD17B7P2	0	broad.mit.edu	37	10	38654432	38654432	+	RNA	SNP	A	A	G	rs2257765		TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr10:38654432A>G	ENST00000494540.1	+	0	599					NR_003086.1																						TCATCTCGCAATGCAAGGAAA	0.453000													3	44					0	0	1	0	0
SLC5A5	6528	broad.mit.edu	37	19	17993012	17993012	+	Missense_Mutation	SNP	G	G	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr19:17993012G>A	ENST00000222248.3	+	10	1573	c.1226G>A	c.(1225-1227)gGa>gAa	p.G409E		NM_000453.2	NP_000444.1	Q92911	SC5A5_HUMAN	solute carrier family 5 (sodium/iodide cotransporter), member 5	409					cellular nitrogen compound metabolic process|cellular response to cAMP|cellular response to gonadotropin stimulus|hormone biosynthetic process	integral to membrane|nucleus|plasma membrane	iodide transmembrane transporter activity|sodium:iodide symporter activity			NS(2)|biliary_tract(1)|central_nervous_system(1)|cervix(1)|endometrium(2)|large_intestine(6)|lung(13)|ovary(1)|prostate(1)|skin(3)	31						TCACTGCTCGGAGGAGGTGTC	0.617000													13	25					0	0	1	0	0
ZNF700	90592	broad.mit.edu	37	19	12060807	12060807	+	Silent	SNP	A	A	G			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr19:12060807A>G	ENST00000482090.1	+	3	2332	c.1914A>G	c.(1912-1914)gcA>gcG	p.A638A	ZNF763_ENST00000590798.1_Intron|CTD-2006C1.12_ENST00000586394.1_RNA|ZNF700_ENST00000254321.5_Silent_p.A656A|ZNF763_ENST00000538752.1_Intron|ZNF763_ENST00000591944.1_Intron			Q9H0M5	ZN700_HUMAN	zinc finger protein 700	656					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding		ZNF700/MAST1_ENST00000251472(2)	breast(1)|cervix(1)|endometrium(4)|kidney(2)|large_intestine(9)|lung(13)|pancreas(1)|prostate(1)|urinary_tract(1)	33						GCGAAAAAGCATTCTGTAAAT	0.418000													6	63					0	0	1	0	0
PPAT	5471	broad.mit.edu	37	4	57261635	57261635	+	Missense_Mutation	SNP	T	T	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr4:57261635T>A	ENST00000264220.2	-	11	1574	c.1437A>T	c.(1435-1437)aaA>aaT	p.K479N		NM_002703.4	NP_002694.3	Q06203	PUR1_HUMAN	phosphoribosyl pyrophosphate amidotransferase	479					glutamine metabolic process|nucleoside metabolic process|purine base biosynthetic process|purine ribonucleoside monophosphate biosynthetic process	cytosol	4 iron, 4 sulfur cluster binding|amidophosphoribosyltransferase activity|metal ion binding			cervix(1)|endometrium(2)|large_intestine(6)|lung(8)|prostate(2)|upper_aerodigestive_tract(1)	20	Glioma(25;0.08)|all_neural(26;0.101)				L-Glutamine(DB00130)|Thioguanine(DB00352)	GCTTTTTCTCTTTCTGTTTTT	0.358000													4	45					0	0	1	0	0
NBAS	51594	broad.mit.edu	37	2	15534433	15534433	+	Missense_Mutation	SNP	T	T	C			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr2:15534433T>C	ENST00000281513.5	-	28	3200	c.3175A>G	c.(3175-3177)Att>Gtt	p.I1059V	NBAS_ENST00000441750.1_Missense_Mutation_p.I939V	NM_015909.3	NP_056993.2	A2RRP1	NBAS_HUMAN	neuroblastoma amplified sequence	1059										NS(4)|breast(4)|central_nervous_system(3)|endometrium(6)|kidney(5)|large_intestine(12)|liver(1)|lung(54)|ovary(2)|pancreas(3)|prostate(9)|skin(6)|stomach(3)	112						ACAAATGAAATTGGTTTCTCG	0.363000													3	50					0	0	1	0	0
ADAMTS1	9510	broad.mit.edu	37	21	28210279	28210279	+	Silent	SNP	G	G	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr21:28210279G>A	ENST00000284984.3	-	9	2977	c.2523C>T	c.(2521-2523)ttC>ttT	p.F841F		NM_006988.3	NP_008919.3	Q9UHI8	ATS1_HUMAN	ADAM metallopeptidase with thrombospondin type 1 motif, 1		Spacer.				integrin-mediated signaling pathway|negative regulation of cell proliferation|proteolysis		heparin binding|zinc ion binding			central_nervous_system(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(12)|lung(20)|ovary(2)|prostate(2)|skin(1)|urinary_tract(1)	42		Breast(209;0.000962)		Lung(58;0.215)		TCTTCTTTACGAAGTAGGTGT	0.443000													3	49					0	0	1	0	0
MEF2A	0	broad.mit.edu	37	15	100211761	100211761	+	Missense_Mutation	SNP	C	C	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr15:100211761C>T	ENST00000354410.5	+	5	924	c.295C>T	c.(295-297)Cca>Tca	p.P99S	MEF2A_ENST00000449277.2_Intron|MEF2A_ENST00000557785.1_Intron|MEF2A_ENST00000558812.1_Intron|MEF2A_ENST00000557942.1_Intron|MEF2A_ENST00000453228.2_Intron|MEF2A_ENST00000338042.6_Intron	NM_005587.2	NP_005578.2	Q02078	MEF2A_HUMAN	myocyte enhancer factor 2A	99					apoptosis|BMK cascade|cardiac conduction|cellular response to calcium ion|dendrite morphogenesis|innate immune response|mitochondrial genome maintenance|mitochondrion distribution|muscle organ development|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|negative regulation of transcription from RNA polymerase II promoter|nerve growth factor receptor signaling pathway|positive regulation of muscle cell differentiation|positive regulation of transcription from RNA polymerase II promoter|stress-activated MAPK cascade|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway|ventricular cardiac myofibril development	nuclear chromatin|nucleoplasm	activating transcription factor binding|histone acetyltransferase binding|histone deacetylase binding|protein heterodimerization activity|RNA polymerase II regulatory region sequence-specific DNA binding|sequence-specific DNA binding RNA polymerase II transcription factor activity|SMAD binding	p.P99S(3)		endometrium(2)|large_intestine(2)|lung(7)|ovary(1)	12	Lung NSC(78;0.00335)|all_lung(78;0.00659)|Melanoma(26;0.00778)|Medulloblastoma(229;0.163)		OV - Ovarian serous cystadenocarcinoma(32;0.00085)			GTGCGACAGCCCAGACCCTGA	0.333000													3	29					0	0	1	0	0
RNF213	57674	broad.mit.edu	37	17	78337016	78337016	+	Missense_Mutation	SNP	C	C	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr17:78337016C>T	ENST00000582970.1	+	40	11613	c.11470C>T	c.(11470-11472)Cgt>Tgt	p.R3824C	RNF213_ENST00000508628.2_Missense_Mutation_p.R3873C|CTD-2047H16.4_ENST00000572151.1_RNA|CTD-2047H16.4_ENST00000575034.1_RNA|RNF213_ENST00000336301.6_Missense_Mutation_p.R1897C	NM_001256071.1	NP_001243000.1	Q9HCF4	ALO17_HUMAN	ring finger protein 213	0										NS(1)|breast(7)|central_nervous_system(1)|cervix(3)|endometrium(12)|haematopoietic_and_lymphoid_tissue(2)|kidney(18)|large_intestine(23)|lung(36)|ovary(11)|pancreas(2)|prostate(4)|skin(3)|stomach(3)|upper_aerodigestive_tract(1)|urinary_tract(3)	130	all_neural(118;0.0538)		BRCA - Breast invasive adenocarcinoma(99;0.0252)|OV - Ovarian serous cystadenocarcinoma(97;0.057)			TTTCAGAAGCCGTCTGCAGAA	0.552000													24	46					0	0	1	0	0
BMS1P20	0	broad.mit.edu	37	22	22664743	22664743	+	RNA	SNP	G	G	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr22:22664743G>A	ENST00000426066.1	+	0	924					NR_027293.1																						CAGACTAAAGGCAAACAAGGA	0.498000													4	23					0	0	1	0	0
MED13	9969	broad.mit.edu	37	17	60033834	60033834	+	Missense_Mutation	SNP	C	C	T			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr17:60033834C>T	ENST00000397786.2	-	24	5565	c.5489G>A	c.(5488-5490)cGg>cAg	p.R1830Q		NM_005121.2	NP_005112.2	Q9UHV7	MED13_HUMAN	mediator complex subunit 13	1830					androgen receptor signaling pathway|positive regulation of transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter	mediator complex	ligand-dependent nuclear receptor transcription coactivator activity|receptor activity|RNA polymerase II transcription cofactor activity|thyroid hormone receptor binding|vitamin D receptor binding			breast(4)|central_nervous_system(1)|endometrium(10)|kidney(24)|large_intestine(15)|liver(1)|lung(20)|ovary(1)|prostate(3)|skin(2)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(2)	88						ACTTTTTTTCCGACGAGCCCT	0.358000													23	64					0	0	1	0	0
AHNAK2	113146	broad.mit.edu	37	14	105418827	105418827	+	Silent	SNP	G	G	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr14:105418827G>A	ENST00000333244.5	-	7	3080	c.2961C>T	c.(2959-2961)gcC>gcT	p.A987A	AHNAK2_ENST00000557457.1_Intron	NM_138420.2	NP_612429.2	Q8IVF2	AHNK2_HUMAN	AHNAK nucleoprotein 2	987						nucleus				cervix(4)|endometrium(4)|large_intestine(3)|lung(14)|ovary(2)|prostate(2)|skin(1)|stomach(3)	33		all_cancers(154;0.115)|Melanoma(154;0.155)|all_epithelial(191;0.183)	all cancers(16;0.000479)|OV - Ovarian serous cystadenocarcinoma(23;0.00659)|Epithelial(46;0.0151)|GBM - Glioblastoma multiforme(11;0.116)			CGTCCTTGTCGGCCAGGGACA	0.617000													8	519					0	0	1	0	0
NUP205	23165	broad.mit.edu	37	7	135282924	135282924	+	Missense_Mutation	SNP	G	G	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr7:135282924G>A	ENST00000285968.6	+	15	2269	c.2243G>A	c.(2242-2244)cGt>cAt	p.R748H	NUP205_ENST00000440390.2_3'UTR	NM_015135.2	NP_055950	Q92621	NU205_HUMAN	nucleoporin 205kDa	748					carbohydrate metabolic process|glucose transport|mRNA transport|protein import into nucleus, docking|regulation of glucose transport|transmembrane transport|viral reproduction	nuclear pore	protein binding			breast(4)|central_nervous_system(2)|endometrium(9)|kidney(7)|large_intestine(17)|liver(4)|lung(36)|ovary(5)|prostate(1)|skin(2)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(3)	93						CTACGATTCCGTACAAGAGCT	0.428000													5	181					0	0	1	0	0
GPR162	27239	broad.mit.edu	37	12	6934826	6934827	+	Frame_Shift_Ins	INS	-	-	A			TCGA-VN-A88M-01A-11D-A34U-08	TCGA-VN-A88M-10A-01D-A34X-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	06941061-7bb1-4dce-9bf7-c107d90e0017	71c317f6-14a3-48e0-a4b2-d53d72060ff3	g.chr12:6934826_6934827insA	ENST00000311268.3	+	3	1832_1833	c.1045_1046insA	c.(1045-1047)gatfs	p.D349fs	GPR162_ENST00000382315.3_Frame_Shift_Ins_p.D45fs|GPR162_ENST00000428545.2_Frame_Shift_Ins_p.D65fs	NM_019858.1	NP_062832.1	Q16538	GP162_HUMAN	G protein-coupled receptor 162	349						integral to membrane|plasma membrane	G-protein coupled receptor activity			NS(1)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(3)|lung(5)|ovary(2)|pancreas(2)|skin(1)	18						GTCTGAGGAGGATGGAGATGAC	0.609											OREG0021636	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	2	4	---	---	---	---					
