Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
MSGN1	343930	broad.mit.edu	37	2	17998326	17998326	+	Missense_Mutation	SNP	C	C	A			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr2:17998326C>A	ENST00000281047.3	+	1	564	c.541C>A	c.(541-543)Ctc>Atc	p.L181I		NM_001105569.1	NP_001099039.1	A6NI15	MSGN1_HUMAN	mesogenin 1	181					cell differentiation|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding			NS(1)|large_intestine(1)|lung(7)|ovary(1)|prostate(1)	11	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.158)					ACTCACAGACCTCCTTAACCG	0.577000													21	22					0.00229938	0.00234728	1	1	0
NPR3	4883	broad.mit.edu	37	5	32724855	32724855	+	Missense_Mutation	SNP	C	C	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr5:32724855C>T	ENST00000265074.8	+	2	1164	c.821C>T	c.(820-822)gCg>gTg	p.A274V	NPR3_ENST00000434067.2_Missense_Mutation_p.A58V|NPR3_ENST00000415685.2_Missense_Mutation_p.A58V|NPR3_ENST00000415167.2_Missense_Mutation_p.A274V	NM_000908.3|NM_001204375.1	NP_000899.1|NP_001191304.1	P17342	ANPRC_HUMAN	natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)	274					osteoclast proliferation|positive regulation of urine volume|regulation of blood pressure|regulation of osteoblast proliferation|skeletal system development	integral to membrane	hormone binding|natriuretic peptide receptor activity			autonomic_ganglia(1)|central_nervous_system(1)|endometrium(2)|large_intestine(5)|lung(12)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)	24					Nesiritide(DB04899)	ATGCTGGTGGCGCACAGGCAT	0.532000													23	25					0	0	1	0	0
DYSF	8291	broad.mit.edu	37	2	71871141	71871141	+	Missense_Mutation	SNP	G	G	A			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr2:71871141G>A	ENST00000258104.3	+	41	4734	c.4457G>A	c.(4456-4458)gGg>gAg	p.G1486E	DYSF_ENST00000409762.1_Missense_Mutation_p.G1503E|DYSF_ENST00000429174.2_Missense_Mutation_p.G1507E|DYSF_ENST00000410020.3_Missense_Mutation_p.G1525E|DYSF_ENST00000479049.2_3'UTR|DYSF_ENST00000409651.1_Missense_Mutation_p.G1518E|DYSF_ENST00000394120.2_Missense_Mutation_p.G1487E|DYSF_ENST00000409582.3_Missense_Mutation_p.G1524E|DYSF_ENST00000409366.1_Missense_Mutation_p.G1508E|DYSF_ENST00000410041.1_Missense_Mutation_p.G1504E|DYSF_ENST00000413539.2_Missense_Mutation_p.G1517E|DYSF_ENST00000409744.1_Missense_Mutation_p.G1494E	NM_001130976.1|NM_003494.3	NP_001124448.1|NP_003485.1	O75923	DYSF_HUMAN	dysferlin	1486						cytoplasmic vesicle membrane|integral to membrane|sarcolemma	calcium-dependent phospholipid binding			autonomic_ganglia(2)|breast(3)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(22)|lung(57)|ovary(3)|pancreas(1)|prostate(2)|skin(6)|upper_aerodigestive_tract(3)|urinary_tract(2)	111						GCCTCCATAGGGGAGAGGGAA	0.512000													4	9					0	0	1	0	0
DISP1	84976	broad.mit.edu	37	1	223178729	223178729	+	Silent	SNP	G	G	A			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr1:223178729G>A	ENST00000284476.6	+	8	4154	c.3990G>A	c.(3988-3990)acG>acA	p.T1330T		NM_032890.3	NP_116279.2	Q96F81	DISP1_HUMAN	dispatched homolog 1 (Drosophila)	1330					diaphragm development|protein homotrimerization|regulation of protein secretion|smoothened signaling pathway	basolateral plasma membrane|integral to membrane	hedgehog receptor activity|peptide transporter activity	p.T1330T(1)		breast(1)|central_nervous_system(1)|cervix(1)|endometrium(7)|kidney(3)|large_intestine(20)|lung(25)|prostate(4)|skin(1)|stomach(1)|urinary_tract(5)	69				GBM - Glioblastoma multiforme(131;0.102)		ACCCCATCACGCACATCCACC	0.557000													8	38					0	0	1	0	0
ZNF733P	643955	broad.mit.edu	37	7	62752443	62752443	+	RNA	SNP	G	G	C			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr7:62752443G>C	ENST00000331425.6	-	0	992					NR_003952.1																						CTTATGTCTAGTAAGGTTTGA	0.438000													3	27					0	0	1	0	0
TSSC2	650368	broad.mit.edu	37	11	3427845	3427845	+	RNA	SNP	C	C	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr11:3427845C>T	ENST00000529482.1	+	0	962																											CTTCAAGTGGCAGGAGCAGAA	0.587000													4	29					0	0	1	0	0
DAK	26007	broad.mit.edu	37	11	61109956	61109956	+	Missense_Mutation	SNP	C	C	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr11:61109956C>T	ENST00000394900.3	+	8	908	c.679C>T	c.(679-681)Cgc>Tgc	p.R227C		NM_015533.3	NP_056348.2	Q3LXA3	DHAK_HUMAN	dihydroxyacetone kinase 2 homolog (S. cerevisiae)	227	DhaK.				glycerol metabolic process	cytosol	ATP binding|FAD-AMP lyase (cyclizing) activity|glycerone kinase activity|metal ion binding			NS(1)|breast(3)|endometrium(3)|large_intestine(5)|lung(8)|prostate(2)|upper_aerodigestive_tract(1)	23						AGCTGGTGTGCGCCGGATAAA	0.592000													4	120					0	0	1	0	0
OBSCN	84033	broad.mit.edu	37	1	228511247	228511247	+	Missense_Mutation	SNP	C	C	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr1:228511247C>T	ENST00000570156.2	+	67	18537	c.18463C>T	c.(18463-18465)Cgc>Tgc	p.R6155C	OBSCN_ENST00000366709.4_Missense_Mutation_p.R2317C|OBSCN_ENST00000366707.4_Missense_Mutation_p.R2832C|OBSCN_ENST00000422127.1_Missense_Mutation_p.R5198C|OBSCN_ENST00000284548.11_Missense_Mutation_p.R5198C	NM_001271223.2	NP_001258152.2	Q5VST9	OBSCN_HUMAN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	5198	Ig-like 53.				apoptosis|cell differentiation|induction of apoptosis by extracellular signals|multicellular organismal development|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|M band|Z disc	ATP binding|metal ion binding|protein binding|protein serine/threonine kinase activity|protein tyrosine kinase activity|Rho guanyl-nucleotide exchange factor activity|structural constituent of muscle|titin binding			NS(2)|breast(7)|central_nervous_system(5)|cervix(2)|endometrium(30)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(37)|lung(89)|ovary(8)|pancreas(3)|prostate(13)|skin(6)|stomach(11)|upper_aerodigestive_tract(2)|urinary_tract(3)	223		Prostate(94;0.0405)				GGGCGTCTACCGCTGCCTGGC	0.572000													7	5					0	0	1	0	0
NPC1L1	29881	broad.mit.edu	37	7	44575860	44575860	+	Missense_Mutation	SNP	C	C	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr7:44575860C>T	ENST00000289547.4	-	4	1904	c.1849G>A	c.(1849-1851)Gct>Act	p.A617T	NPC1L1_ENST00000546276.1_Missense_Mutation_p.A617T|NPC1L1_ENST00000423141.1_Missense_Mutation_p.A617T|NPC1L1_ENST00000381160.3_Missense_Mutation_p.A617T	NM_013389.2	NP_037521.2	Q9UHC9	NPCL1_HUMAN	NPC1-like 1	617					cholesterol biosynthetic process|intestinal cholesterol absorption|lipoprotein metabolic process	apical plasma membrane|cytoplasmic vesicle membrane|integral to membrane	hedgehog receptor activity|protein binding			breast(1)|central_nervous_system(2)|cervix(1)|endometrium(4)|large_intestine(7)|lung(27)|ovary(6)|prostate(2)|skin(2)|upper_aerodigestive_tract(3)|urinary_tract(2)	57					Ezetimibe(DB00973)	CCTACCTCAGCCATGAACGTG	0.637000													4	68					0	0	1	0	0
PHF3	23469	broad.mit.edu	37	6	64404570	64404570	+	Missense_Mutation	SNP	C	C	T	rs139681301		TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr6:64404570C>T	ENST00000262043.3	+	6	2936	c.2596C>T	c.(2596-2598)Cgg>Tgg	p.R866W	PHF3_ENST00000393387.1_Missense_Mutation_p.R866W			Q92576	PHF3_HUMAN	PHD finger protein 3	866					multicellular organismal development|transcription, DNA-dependent	nucleus	zinc ion binding	p.R866R(1)		breast(7)|cervix(2)|endometrium(8)|kidney(7)|large_intestine(18)|lung(21)|ovary(3)|prostate(1)|skin(2)|upper_aerodigestive_tract(6)	75	all_cancers(3;0.0241)|all_epithelial(2;0.00306)|Lung NSC(77;0.121)		LUSC - Lung squamous cell carcinoma(74;0.0644)|Lung(124;0.148)			AGTTTTACCTCGGAGATCCTC	0.403000													6	168					0	0	1	0	0
GRWD1	83743	broad.mit.edu	37	19	48953645	48953645	+	Missense_Mutation	SNP	C	C	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr19:48953645C>T	ENST00000253237.5	+	4	777	c.544C>T	c.(544-546)Cgg>Tgg	p.R182W		NM_031485.3	NP_113673.3	Q9BQ67	GRWD1_HUMAN	glutamate-rich WD repeat containing 1	182						nucleolus				endometrium(1)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(3)|lung(10)|ovary(1)|stomach(1)	19		all_lung(116;0.000147)|Lung NSC(112;0.000251)|all_epithelial(76;0.000326)|all_neural(266;0.0506)|Ovarian(192;0.113)		OV - Ovarian serous cystadenocarcinoma(262;0.000206)|all cancers(93;0.000207)|Epithelial(262;0.0125)|GBM - Glioblastoma multiforme(486;0.0222)		TGCGCTGCGGCGGCTTCTGCA	0.647000													10	21					0	0	1	0	0
ZNF91	7644	broad.mit.edu	37	19	23544148	23544148	+	Missense_Mutation	SNP	G	G	C			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr19:23544148G>C	ENST00000300619.7	-	4	1838	c.1633C>G	c.(1633-1635)Ccc>Gcc	p.P545A	ZNF91_ENST00000397082.2_Missense_Mutation_p.P513A|ZNF91_ENST00000599743.1_Intron	NM_003430.2	NP_003421.2	Q05481	ZNF91_HUMAN	zinc finger protein 91	545						nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding						all_lung(12;0.0349)|Lung NSC(12;0.0538)|all_epithelial(12;0.0611)				CATTTGTAGGGTTTCTCTCTA	0.328000													11	30					0	0	1	0	0
CELSR2	1952	broad.mit.edu	37	1	109815272	109815272	+	Missense_Mutation	SNP	G	G	A			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr1:109815272G>A	ENST00000271332.3	+	30	8126	c.8065G>A	c.(8065-8067)Gca>Aca	p.A2689T	CELSR2_ENST00000498157.1_3'UTR	NM_001408.2	NP_001399.1	Q9HCU4	CELR2_HUMAN	cadherin, EGF LAG seven-pass G-type receptor 2	2689					dendrite morphogenesis|homophilic cell adhesion|neural plate anterior/posterior regionalization|neuropeptide signaling pathway|regulation of cell-cell adhesion|regulation of transcription, DNA-dependent|Wnt receptor signaling pathway	cytoplasm|integral to membrane|plasma membrane	calcium ion binding|G-protein coupled receptor activity|protein binding			NS(1)|autonomic_ganglia(1)|breast(3)|central_nervous_system(1)|cervix(3)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(14)|lung(27)|ovary(5)|prostate(1)|skin(3)|urinary_tract(2)	82		all_epithelial(167;0.000114)|all_lung(203;0.000321)|Lung NSC(277;0.000626)|Breast(1374;0.244)		Colorectal(144;0.0296)|Lung(183;0.067)|COAD - Colon adenocarcinoma(174;0.114)|Epithelial(280;0.193)|all cancers(265;0.219)		GGAGGAGTCCGCACTGAACCC	0.647000													3	23					0	0	1	0	0
FAM86EP	348926	broad.mit.edu	37	4	3954857	3954857	+	RNA	SNP	C	C	A	rs17410899		TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr4:3954857C>A	ENST00000281228.8	-	0	141				FAM86EP_ENST00000313946.8_RNA																							AATATCCCGCCGCAGCTCAGA	0.488000													3	56					0.004672	0.004672	1	1	0
OR8H3	390152	broad.mit.edu	37	11	55890648	55890648	+	Missense_Mutation	SNP	C	C	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr11:55890648C>T	ENST00000313472.3	+	1	800	c.800C>T	c.(799-801)tCc>tTc	p.S267F		NM_001005201.1	NP_001005201.1	Q8N146	OR8H3_HUMAN	olfactory receptor, family 8, subfamily H, member 3	267					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(30)|ovary(2)|prostate(1)|skin(3)|stomach(1)	42	Esophageal squamous(21;0.00693)					AAGTCTTATTCCTTGGGAAGA	0.378000													29	108					0	0	1	0	0
LOC150776	150776	broad.mit.edu	37	2	132276650	132276650	+	RNA	SNP	G	G	C	rs28712373	by1000genomes	TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr2:132276650G>C	ENST00000438378.2	+	0	1970					NR_026922.1																						GCTCATCACAGAGGCCAAACA	0.632000													5	19					0	0	1	0	0
CUBN	8029	broad.mit.edu	37	10	16941019	16941019	+	Silent	SNP	T	T	C			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr10:16941019T>C	ENST00000377833.4	-	54	8639	c.8574A>G	c.(8572-8574)ggA>ggG	p.G2858G		NM_001081.3	NP_001072.2	O60494	CUBN_HUMAN	cubilin (intrinsic factor-cobalamin receptor)	2858	CUB 21.				cholesterol metabolic process|cobalamin transport|hormone biosynthetic process|lipoprotein metabolic process|receptor-mediated endocytosis|tissue homeostasis|vitamin D metabolic process	brush border membrane|cytosol|endosome membrane|extrinsic to external side of plasma membrane|lysosomal lumen|lysosomal membrane	calcium ion binding|cobalamin binding|protein homodimerization activity|receptor activity|transporter activity			breast(8)|central_nervous_system(4)|cervix(1)|endometrium(18)|haematopoietic_and_lymphoid_tissue(3)|kidney(12)|large_intestine(42)|liver(1)|lung(107)|ovary(9)|pancreas(2)|prostate(3)|skin(9)|stomach(3)|upper_aerodigestive_tract(11)|urinary_tract(8)	241					Cyanocobalamin(DB00115)|Hydroxocobalamin(DB00200)	TCTGACATTGTCCATCACCGC	0.403000													38	73					0	0	1	0	0
TPTE	7179	broad.mit.edu	37	21	10943011	10943011	+	Missense_Mutation	SNP	A	A	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr21:10943011A>T	ENST00000298232.7	-	11	889	c.522T>A	c.(520-522)caT>caA	p.H174Q	TPTE_ENST00000342420.5_Missense_Mutation_p.H154Q|TPTE_ENST00000361285.4_Missense_Mutation_p.H192Q|TPTE_ENST00000415664.2_5'UTR	NM_199259.2	NP_954868	P56180	TPTE_HUMAN	transmembrane phosphatase with tensin homology	192					signal transduction	integral to membrane	ion channel activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity			NS(1)|breast(1)|central_nervous_system(2)|cervix(2)|endometrium(11)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(19)|lung(76)|ovary(2)|prostate(2)|skin(8)|urinary_tract(1)	130			Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		GTCGAAGTAAATGTGTCCATC	0.328000													10	64					0	0	1	0	0
VGLL2	245806	broad.mit.edu	37	6	117593623	117593623	+	Missense_Mutation	SNP	G	G	A			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr6:117593623G>A	ENST00000326274.5	+	4	1110	c.920G>A	c.(919-921)cGt>cAt	p.R307H	VGLL2_ENST00000352536.3_Missense_Mutation_p.R133H	NM_182645.3	NP_872586.1	Q8N8G2	VGLL2_HUMAN	vestigial like 2 (Drosophila)	307					transcription, DNA-dependent	nucleus				central_nervous_system(1)|kidney(1)|lung(3)	5				GBM - Glioblastoma multiforme(226;0.0254)|all cancers(137;0.0676)|OV - Ovarian serous cystadenocarcinoma(136;0.0757)		GCAGCTCGTCGTTATTCCCTC	0.532000													102	206					0	0	1	0	0
IDH1	3417	broad.mit.edu	37	2	209113112	209113112	+	Missense_Mutation	SNP	C	C	T	rs121913500		TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr2:209113112C>T	ENST00000415913.1	-	4	776	c.395G>A	c.(394-396)cGt>cAt	p.R132H	IDH1_ENST00000345146.2_Missense_Mutation_p.R132H|IDH1_ENST00000446179.1_Missense_Mutation_p.R132H	NM_001282387.1	NP_001269316.1	O75874	IDHC_HUMAN	isocitrate dehydrogenase 1 (NADP+), soluble	132			R -> C (in colorectal cancer and glioma samples; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha- ketoglutarate but instead alpha- ketoglutarate is converted to R(-)-2- hydroxyglutarate).|R -> G (in a glioma sample; glioblastoma multiforme; somatic mutation).|R -> H (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> L (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).|R -> S (in a glioma sample; glioblastoma multiforme; somatic mutation; abolishes magnesium binding and alters enzyme activity so that isocitrate is no longer converted to alpha-ketoglutarate but instead alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate).		2-oxoglutarate metabolic process|cellular lipid metabolic process|glyoxylate cycle|isocitrate metabolic process|NADPH regeneration|tricarboxylic acid cycle	cytosol|peroxisomal matrix	isocitrate dehydrogenase (NADP+) activity|magnesium ion binding|NAD binding|protein homodimerization activity	p.R132H(2774)|p.R132L(59)|p.R132V(1)|p.G131_R132>VL(1)		NS(1)|autonomic_ganglia(2)|biliary_tract(24)|bone(237)|central_nervous_system(3764)|endometrium(3)|haematopoietic_and_lymphoid_tissue(794)|kidney(2)|large_intestine(7)|lung(7)|prostate(6)|skin(5)|soft_tissue(12)|thyroid(22)|urinary_tract(1)	4887				Epithelial(149;0.0322)|LUSC - Lung squamous cell carcinoma(261;0.0711)|Lung(261;0.136)		ATAAGCATGACGACCTATGAT	0.393000			Mis		gliobastoma								20	44					0	0	1	0	0
HNF1B	6928	broad.mit.edu	37	17	36104728	36104728	+	Missense_Mutation	SNP	G	G	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr17:36104728G>T	ENST00000225893.4	-	1	509	c.148C>A	c.(148-150)Cct>Act	p.P50T	HNF1B_ENST00000561193.1_Missense_Mutation_p.P50T|HNF1B_ENST00000427275.2_Missense_Mutation_p.P50T|HNF1B_ENST00000560016.1_Missense_Mutation_p.P50T	NM_000458.2|NM_001165923.1	NP_000449.1|NP_001159395.1	P35680	HNF1B_HUMAN	HNF1 homeobox B	50					endocrine pancreas development|genitalia development|kidney development|positive regulation of transcription initiation from RNA polymerase II promoter|positive regulation of transcription, DNA-dependent|pronephric nephron tubule development|regulation of pronephros size	nucleus	DNA binding|protein homodimerization activity|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			breast(2)|central_nervous_system(3)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(6)|kidney(3)|large_intestine(2)|liver(1)|lung(3)|ovary(3)|prostate(1)|skin(2)	28		Breast(25;0.00765)|Ovarian(249;0.15)	STAD - Stomach adenocarcinoma(1;0.0142)			CCGCTGCCAGGGGACAGGGGC	0.682000													10	25					7.48243e-07	7.97041e-07	1	1	0
ECT2L	345930	broad.mit.edu	37	6	139186182	139186182	+	Missense_Mutation	SNP	C	C	G			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr6:139186182C>G	ENST00000423192.1	+	11	1502	c.1341C>G	c.(1339-1341)atC>atG	p.I447M	ECT2L_ENST00000541398.1_Missense_Mutation_p.I378M|ECT2L_ENST00000495970.1_3'UTR|ECT2L_ENST00000367682.2_Missense_Mutation_p.I447M			Q008S8	ECT2L_HUMAN	epithelial cell transforming sequence 2 oncogene-like	447					regulation of Rho protein signal transduction	intracellular	Rho guanyl-nucleotide exchange factor activity			breast(1)|central_nervous_system(1)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(3)|kidney(1)|large_intestine(7)|lung(12)|skin(1)|upper_aerodigestive_tract(1)	30						CCTCTTCCATCTACTTCTGCG	0.453000			"""N, Splice, Mis"""		ETP ALL								9	27					0	0	1	0	0
HUS1B	135458	broad.mit.edu	37	6	656483	656483	+	Silent	SNP	G	G	A			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr6:656483G>A	ENST00000380907.2	-	1	480	c.462C>T	c.(460-462)gaC>gaT	p.D154D	EXOC2_ENST00000448181.3_Intron|EXOC2_ENST00000230449.4_Intron	NM_148959.3	NP_683762.2	Q8NHY5	HUS1B_HUMAN	HUS1 checkpoint homolog b (S. pombe)	154										endometrium(3)|large_intestine(1)|lung(7)	11	Ovarian(93;0.0733)	Breast(5;0.00139)|all_lung(73;0.0691)|all_hematologic(90;0.0895)		OV - Ovarian serous cystadenocarcinoma(45;0.041)|BRCA - Breast invasive adenocarcinoma(62;0.0965)		GGATGCTCGCGTCGGAGGCGC	0.701000													18	57					0	0	1	0	0
DPP4	1803	broad.mit.edu	37	2	162881325	162881325	+	Missense_Mutation	SNP	T	T	C			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr2:162881325T>C	ENST00000360534.3	-	11	1572	c.1012A>G	c.(1012-1014)Aac>Gac	p.N338D		NM_001935.3	NP_001926.2	P27487	DPP4_HUMAN	dipeptidyl-peptidase 4	338					cell adhesion|endothelial cell migration|negative regulation of extracellular matrix disassembly|positive regulation of cell proliferation|proteolysis|regulation of cell-cell adhesion mediated by integrin|response to hypoxia|T cell activation|T cell costimulation	apical plasma membrane|cell surface|endocytic vesicle|extracellular region|integral to membrane|invadopodium membrane|lamellipodium membrane|membrane raft	aminopeptidase activity|dipeptidyl-peptidase activity|protease binding|protein homodimerization activity|receptor activity|receptor binding|serine-type endopeptidase activity			breast(3)|central_nervous_system(1)|cervix(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(7)|liver(1)|lung(21)|ovary(3)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	48					Sitagliptin(DB01261)	ACTAAGCAGTTCCATCTTCCA	0.463000													84	113					0	0	1	0	0
BRCA2	675	broad.mit.edu	37	13	32907209	32907209	+	Missense_Mutation	SNP	G	G	A	rs138734772		TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr13:32907209G>A	ENST00000544455.1	+	10	1821	c.1594G>A	c.(1594-1596)Gaa>Aaa	p.E532K	BRCA2_ENST00000380152.3_Missense_Mutation_p.E532K	NM_000059.3	NP_000050	P51587	BRCA2_HUMAN	breast cancer 2, early onset	532					cell cycle cytokinesis|centrosome duplication|double-strand break repair via homologous recombination|negative regulation of mammary gland epithelial cell proliferation|nucleotide-excision repair|positive regulation of transcription, DNA-dependent|regulation of S phase of mitotic cell cycle	BRCA2-MAGE-D1 complex|centrosome|nucleoplasm|stored secretory granule	gamma-tubulin binding|H3 histone acetyltransferase activity|H4 histone acetyltransferase activity|protease binding|single-stranded DNA binding			NS(3)|breast(13)|central_nervous_system(5)|cervix(2)|endometrium(24)|haematopoietic_and_lymphoid_tissue(1)|kidney(10)|large_intestine(32)|liver(1)|lung(41)|oesophagus(5)|ovary(22)|pancreas(4)|prostate(3)|salivary_gland(1)|skin(11)|upper_aerodigestive_tract(2)|urinary_tract(3)	183		Lung SC(185;0.0262)		all cancers(112;7.13e-07)|Epithelial(112;1.59e-05)|OV - Ovarian serous cystadenocarcinoma(117;0.000732)|BRCA - Breast invasive adenocarcinoma(63;0.0291)|GBM - Glioblastoma multiforme(144;0.0704)		CTTTAAAAAAGAAACTGAAGC	0.368000			"""D, Mis, N, F, S"""		"""breast, ovarian, pancreatic"""	"""breast, ovarian, pancreatic, leukemia  (FANCB, FANCD1)"""		Homologous recombination	Pancreatic Cancer, Familial Clustering of;Li-Fraumeni syndrome;Hereditary Prostate Cancer;Hereditary Breast-Ovarian Cancer, BRCA2 type;Fanconi Anemia type D1, bi-allelic BRCA2 mutations;Fanconi Anemia	TCGA Ovarian(8;0.087)			36	105					0	0	1	0	0
ITLN1	55600	broad.mit.edu	37	1	160851959	160851959	+	Missense_Mutation	SNP	T	T	C			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr1:160851959T>C	ENST00000326245.3	-	4	308	c.193A>G	c.(193-195)Atc>Gtc	p.I65V		NM_017625.2	NP_060095.2	Q8WWA0	ITLN1_HUMAN	intelectin 1 (galactofuranose binding)	65	Fibrinogen C-terminal.				positive regulation of glucose import|positive regulation of protein phosphorylation|response to nematode|signal transduction	anchored to membrane|brush border membrane|extracellular region|membrane raft	receptor binding|sugar binding			breast(1)|central_nervous_system(1)|endometrium(4)|kidney(1)|large_intestine(1)|lung(6)|ovary(2)|pancreas(1)|skin(3)|upper_aerodigestive_tract(1)	21	all_cancers(52;2.99e-17)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.00737)			GTCTGGTAGATAACACCATTC	0.577000													4	37					0	0	1	0	0
OR10R2	343406	broad.mit.edu	37	1	158450457	158450457	+	Missense_Mutation	SNP	C	C	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr1:158450457C>T	ENST00000368152.1	+	1	790	c.790C>T	c.(790-792)Cac>Tac	p.H264Y	RP11-144L1.4_ENST00000426251.1_RNA|RP11-144L1.4_ENST00000419738.1_RNA	NM_001004472.1	NP_001004472.1	Q8NGX6	O10R2_HUMAN	olfactory receptor, family 10, subfamily R, member 2	264					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|endometrium(1)|kidney(1)|large_intestine(2)|liver(1)|lung(26)|pancreas(3)|prostate(2)|skin(3)|upper_aerodigestive_tract(1)	41	all_hematologic(112;0.0378)					CTGCGCCTCTCACCTCAGTGT	0.478000													22	39					0	0	1	0	0
DCTN1	1639	broad.mit.edu	37	2	74595107	74595107	+	Missense_Mutation	SNP	C	C	T	rs140523637		TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr2:74595107C>T	ENST00000361874.3	-	17	2323	c.2006G>A	c.(2005-2007)cGc>cAc	p.R669H	DCTN1_ENST00000409438.1_Missense_Mutation_p.R535H|DCTN1_ENST00000495643.1_5'UTR|DCTN1_ENST00000409567.3_Missense_Mutation_p.R649H|DCTN1_ENST00000407639.2_Missense_Mutation_p.R535H|DCTN1_ENST00000394003.3_Missense_Mutation_p.R662H|DCTN1_ENST00000409240.1_Missense_Mutation_p.R632H|DCTN1_ENST00000409868.1_Missense_Mutation_p.R652H	NM_004082.4	NP_004073.2	Q14203	DCTN1_HUMAN	dynactin 1	669					cell death|G2/M transition of mitotic cell cycle|mitosis|nervous system development	centrosome|cytosol|kinetochore|microtubule|spindle pole	motor activity|protein binding			breast(2)|central_nervous_system(1)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(7)|lung(20)|ovary(4)|prostate(1)|skin(3)	45						CTGCTCATAGCGGTGTAGCGT	0.617000													7	24					0	0	1	0	0
LMTK2	22853	broad.mit.edu	37	7	97821950	97821950	+	Missense_Mutation	SNP	T	T	G			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr7:97821950T>G	ENST00000297293.5	+	11	2466	c.2173T>G	c.(2173-2175)Ttt>Gtt	p.F725V		NM_014916.3	NP_055731.2	Q8IWU2	LMTK2_HUMAN	lemur tyrosine kinase 2	725					early endosome to late endosome transport|endocytic recycling|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|protein autophosphorylation|receptor recycling|transferrin transport	early endosome|Golgi apparatus|integral to membrane|perinuclear region of cytoplasm|recycling endosome	ATP binding|myosin VI binding|protein phosphatase inhibitor activity|protein serine/threonine kinase activity|protein tyrosine kinase activity			NS(2)|breast(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(13)|lung(25)|ovary(1)|pancreas(2)|skin(2)|stomach(3)	59	all_cancers(62;3.23e-09)|all_epithelial(64;7.65e-10)|Lung NSC(181;0.00902)|all_lung(186;0.0104)|Esophageal squamous(72;0.0125)					AAACTTTTTATTTCTTCAAGA	0.328000													12	59					0	0	1	0	0
BRD3	8019	broad.mit.edu	37	9	136901336	136901336	+	Missense_Mutation	SNP	T	T	C			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr9:136901336T>C	ENST00000303407.7	-	10	1939	c.1754A>G	c.(1753-1755)aAc>aGc	p.N585S	BRD3_ENST00000473349.1_5'UTR|BRD3_ENST00000371834.2_3'UTR	NM_007371.3	NP_031397.1	Q15059	BRD3_HUMAN	bromodomain containing 3	585						nucleus	protein binding		BRD3/C15orf55(3)	kidney(1)|skin(1)|stomach(4)	6				OV - Ovarian serous cystadenocarcinoma(145;1.43e-08)|Epithelial(140;8.41e-08)|all cancers(34;5.21e-07)		GGGCAGCCGGTTGATGTCCAG	0.592000			T	C15orf55	lethal midline carcinoma of young people								9	20					0	0	1	0	0
DNAJC6	9829	broad.mit.edu	37	1	65871611	65871611	+	Silent	SNP	G	G	A			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr1:65871611G>A	ENST00000395325.3	+	16	2272	c.2115G>A	c.(2113-2115)ccG>ccA	p.P705P	DNAJC6_ENST00000371069.4_Silent_p.P762P|DNAJC6_ENST00000263441.7_Silent_p.P692P	NM_014787.3	NP_055602.1	O75061	AUXI_HUMAN	DnaJ (Hsp40) homolog, subfamily C, member 6	705	Pro-rich.				cellular membrane organization|post-Golgi vesicle-mediated transport	cytosol	heat shock protein binding|protein tyrosine phosphatase activity|SH3 domain binding			NS(1)|breast(3)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(22)|ovary(1)|prostate(2)|skin(1)	39						GAGGATTCCCGCCTCTCAGCT	0.537000													19	6					0	0	1	0	0
RASAL2	9462	broad.mit.edu	37	1	178427644	178427644	+	Missense_Mutation	SNP	A	A	G			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr1:178427644A>G	ENST00000448150.3	+	14	4002	c.3184A>G	c.(3184-3186)Aaa>Gaa	p.K1062E	RASAL2_ENST00000367649.3_Missense_Mutation_p.K1073E|RASAL2_ENST00000462775.1_Missense_Mutation_p.K932E	NM_170692.2	NP_733793.2	Q9UJF2	NGAP_HUMAN	RAS protein activator like 2	932					negative regulation of Ras protein signal transduction|signal transduction	cytoplasm|intrinsic to internal side of plasma membrane	Ras GTPase activator activity			biliary_tract(1)|breast(3)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(9)|liver(2)|lung(25)|ovary(2)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	54						CCCTGTTCCCAAAGTTAGAGC	0.562000													22	35					0	0	1	0	0
NDUFB5	4711	broad.mit.edu	37	3	179336258	179336258	+	Missense_Mutation	SNP	A	A	G			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr3:179336258A>G	ENST00000493866.1	+	3	267	c.242A>G	c.(241-243)tAt>tGt	p.Y81C	NDUFB5_ENST00000259037.3_Missense_Mutation_p.Y133C|NDUFB5_ENST00000472629.1_Missense_Mutation_p.Y121C|NDUFB5_ENST00000473500.1_3'UTR	NM_001199957.1	NP_001186886.1	O43674	NDUB5_HUMAN	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa	133					mitochondrial electron transport, NADH to ubiquinone|transport	integral to membrane|mitochondrial respiratory chain complex I	NADH dehydrogenase (ubiquinone) activity			endometrium(1)|lung(6)|skin(1)	8	all_cancers(143;9.62e-16)|Ovarian(172;0.0172)|Breast(254;0.191)		OV - Ovarian serous cystadenocarcinoma(80;5.98e-26)|GBM - Glioblastoma multiforme(14;0.0169)|BRCA - Breast invasive adenocarcinoma(182;0.18)		NADH(DB00157)	GAAAAGATATATGAAAGAACA	0.378000													9	25					0	0	1	0	0
ACSS3	79611	broad.mit.edu	37	12	81503360	81503360	+	Silent	SNP	C	C	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr12:81503360C>T	ENST00000548058.1	+	2	1243	c.333C>T	c.(331-333)aaC>aaT	p.N111N	RP11-543H12.1_ENST00000547123.1_RNA|ACSS3_ENST00000261206.3_Silent_p.N110N			Q9H6R3	ACSS3_HUMAN	acyl-CoA synthetase short-chain family member 3	111						mitochondrion	acetate-CoA ligase activity|ATP binding			NS(1)|breast(2)|central_nervous_system(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(5)|kidney(2)|large_intestine(7)|liver(3)|lung(20)|ovary(1)|skin(4)|upper_aerodigestive_tract(2)	51						GAATGCTTAACATTTGTTACA	0.313000													16	24					0	0	1	0	0
KAT6A	7994	broad.mit.edu	37	8	41798681	41798681	+	Silent	SNP	T	T	C			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr8:41798681T>C	ENST00000396930.3	-	16	3261	c.2718A>G	c.(2716-2718)tcA>tcG	p.S906S	KAT6A_ENST00000265713.2_Silent_p.S906S|KAT6A_ENST00000406337.1_Silent_p.S906S	NM_001099412.1	NP_001092882.1	Q92794	MYST3_HUMAN	K(lysine) acetyltransferase 6A	906					histone H3 acetylation|myeloid cell differentiation|negative regulation of transcription, DNA-dependent|nucleosome assembly|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	MOZ/MORF histone acetyltransferase complex|nucleosome	DNA binding|histone acetyltransferase activity|transcription coactivator activity|transcription factor binding|zinc ion binding										GGGTGGCTTCTGATTTCTCCC	0.483000													20	35					0	0	1	0	0
KANSL1L	151050	broad.mit.edu	37	2	211019256	211019256	+	Silent	SNP	A	A	G			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr2:211019256A>G	ENST00000281772.9	-	2	314	c.51T>C	c.(49-51)tcT>tcC	p.S17S	KANSL1L_ENST00000429908.2_5'UTR|KANSL1L_ENST00000457374.1_Silent_p.S17S|KANSL1L_ENST00000418791.1_Silent_p.S17S|KANSL1L_ENST00000452086.1_Silent_p.S17S	NM_152519.2	NP_689732.2	A0AUZ9	CB067_HUMAN	KAT8 regulatory NSL complex subunit 1-like	17																	TACTTGGCAAAGATGAAAAGC	0.423000													5	94					0	0	1	0	0
OR2T3	343173	broad.mit.edu	37	1	248637377	248637377	+	Silent	SNP	C	C	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr1:248637377C>T	ENST00000359594.2	+	1	751	c.726C>T	c.(724-726)gcC>gcT	p.A242A		NM_001005495.1	NP_001005495.1	Q8NH03	OR2T3_HUMAN	olfactory receptor, family 2, subfamily T, member 3	242					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(2)|endometrium(5)|lung(19)|ovary(1)|prostate(1)|skin(3)	31	all_cancers(71;0.000108)|all_epithelial(71;1.03e-05)|Breast(184;0.00909)|Ovarian(71;0.0377)|all_lung(81;0.127)|Lung NSC(105;0.136)		OV - Ovarian serous cystadenocarcinoma(106;0.0265)			ACAGGAAGGCCTTGGCCACCT	0.567000													79	108					0	0	1	0	0
ACSL4	2182	broad.mit.edu	37	X	108911384	108911384	+	Missense_Mutation	SNP	T	T	C			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chrX:108911384T>C	ENST00000340800.2	-	12	1888	c.1384A>G	c.(1384-1386)Att>Gtt	p.I462V	ACSL4_ENST00000469796.2_Missense_Mutation_p.I462V|ACSL4_ENST00000348502.6_Missense_Mutation_p.I421V	NM_022977.2	NP_075266.1	O60488	ACSL4_HUMAN	acyl-CoA synthetase long-chain family member 4	462					fatty acid metabolic process|learning or memory|long-chain fatty-acyl-CoA biosynthetic process|triglyceride biosynthetic process	endoplasmic reticulum membrane|integral to membrane|microsome|mitochondrial outer membrane|peroxisomal membrane	ATP binding|long-chain fatty acid-CoA ligase activity			breast(3)|central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(6)|lung(6)|ovary(2)	22					Icosapent(DB00159)|Troglitazone(DB00197)	CCCTGGCCAATTGGGCAGCAG	0.498000													5	104					0	0	1	0	0
OR5AC2	81050	broad.mit.edu	37	3	97806631	97806631	+	Silent	SNP	T	T	A			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr3:97806631T>A	ENST00000358642.2	+	1	615	c.615T>A	c.(613-615)ggT>ggA	p.G205G		NM_054106.1	NP_473447.1	Q9NZP5	O5AC2_HUMAN	olfactory receptor, family 5, subfamily AC, member 2	205					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			endometrium(4)|large_intestine(3)|lung(13)|pancreas(1)|prostate(2)|skin(4)|urinary_tract(1)	28						TTATTTTTGGTGCTTTTATAC	0.299000													17	19					0	0	1	0	0
MRGPRX3	117195	broad.mit.edu	37	11	18158872	18158872	+	Silent	SNP	G	G	A			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr11:18158872G>A	ENST00000396275.2	+	3	484	c.123G>A	c.(121-123)gcG>gcA	p.A41A		NM_054031.3	NP_473372.3	Q96LB0	MRGX3_HUMAN	MAS-related GPR, member X3	41						integral to membrane|plasma membrane	G-protein coupled receptor activity			NS(1)|breast(2)|endometrium(2)|kidney(1)|large_intestine(5)|lung(10)|ovary(1)|pancreas(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(2)	27						CCCTTGTCGCGCTGACAGGAA	0.592000													4	110					0	0	1	0	0
CLIP1	6249	broad.mit.edu	37	12	122812878	122812878	+	Missense_Mutation	SNP	T	T	C			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr12:122812878T>C	ENST00000358808.2	-	15	3084	c.2930A>G	c.(2929-2931)cAg>cGg	p.Q977R	CLIP1_ENST00000361654.4_Missense_Mutation_p.Q866R|CLIP1_ENST00000545889.1_Missense_Mutation_p.Q563R|CLIP1_ENST00000537178.1_Missense_Mutation_p.Q942R|CLIP1_ENST00000540338.1_Missense_Mutation_p.Q988R|CLIP1_ENST00000302528.7_Missense_Mutation_p.Q977R	NM_001247997.1|NM_002956.2	NP_001234926.1|NP_002947.1	P30622	CLIP1_HUMAN	CAP-GLY domain containing linker protein 1	988					mitotic prometaphase|positive regulation of microtubule polymerization	centrosome|cytosol|endosome|intermediate filament|kinetochore	nucleic acid binding|protein homodimerization activity|zinc ion binding			NS(1)|breast(5)|endometrium(4)|kidney(5)|large_intestine(16)|liver(1)|lung(21)|ovary(2)|prostate(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	60	all_neural(191;0.0837)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;1.81e-05)|Epithelial(86;6.85e-05)|BRCA - Breast invasive adenocarcinoma(302;0.226)		TTGCTGGCTCTGTTCAGCTTT	0.403000													106	143					0	0	1	0	0
TBC1D22A	25771	broad.mit.edu	37	22	47287286	47287286	+	Missense_Mutation	SNP	G	G	A			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr22:47287286G>A	ENST00000337137.4	+	6	999	c.833G>A	c.(832-834)aGg>aAg	p.R278K	TBC1D22A_ENST00000407381.3_Missense_Mutation_p.R219K|TBC1D22A_ENST00000406733.1_Missense_Mutation_p.R231K|TBC1D22A_ENST00000355704.3_Missense_Mutation_p.R200K|TBC1D22A_ENST00000380995.1_Missense_Mutation_p.R231K	NM_001284304.1|NM_001284305.1|NM_014346.2	NP_001271233.1|NP_001271234.1|NP_055161.1	Q8WUA7	TB22A_HUMAN	TBC1 domain family, member 22A	278	Rab-GAP TBC.					intracellular	protein homodimerization activity|Rab GTPase activator activity			breast(1)|endometrium(3)|large_intestine(10)|lung(5)|ovary(2)|prostate(1)	22		all_cancers(38;4.44e-05)|all_epithelial(38;0.000507)|Breast(42;0.0488)|all_lung(38;0.0682)|Ovarian(80;0.0731)|all_neural(38;0.0966)|Glioma(61;0.222)|Lung SC(80;0.236)		UCEC - Uterine corpus endometrioid carcinoma (28;0.0347)|BRCA - Breast invasive adenocarcinoma(115;0.231)		GACACATACAGGCAGGTGGGA	0.403000													4	90					0	0	1	0	0
UGT2B17	7367	broad.mit.edu	37	4	69433683	69433683	+	Missense_Mutation	SNP	G	G	A			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr4:69433683G>A	ENST00000317746.2	-	1	562	c.520C>T	c.(520-522)Cgc>Tgc	p.R174C		NM_001077.3	NP_001068.1	O75795	UDB17_HUMAN	UDP glucuronosyltransferase 2 family, polypeptide B17	174					steroid metabolic process	endoplasmic reticulum membrane|integral to membrane|microsome	glucuronosyltransferase activity			central_nervous_system(1)|endometrium(4)|kidney(1)|large_intestine(7)|lung(14)|ovary(2)|prostate(1)	30						ACAGAGAAGCGGAGACTGTAC	0.438000													10	180					0	0	1	0	0
PTGFRN	5738	broad.mit.edu	37	1	117487361	117487361	+	Frame_Shift_Del	DEL	G	G	-			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr1:117487361delG	ENST00000393203.2	+	3	626	c.479delG	c.(478-480)cggfs	p.R160fs		NM_020440.2	NP_065173.2	Q9P2B2	FPRP_HUMAN	prostaglandin F2 receptor inhibitor	160	Ig-like C2-type 2.					endoplasmic reticulum membrane|Golgi apparatus|integral to membrane	protein binding			NS(1)|breast(1)|endometrium(4)|large_intestine(10)|liver(1)|lung(22)|ovary(1)|prostate(4)|stomach(1)|upper_aerodigestive_tract(1)	46	Lung SC(450;0.225)	all_cancers(81;0.00104)|all_lung(203;8.97e-05)|all_epithelial(167;0.000139)|Lung NSC(69;0.000446)		Lung(183;0.0704)|LUSC - Lung squamous cell carcinoma(189;0.227)|Colorectal(144;0.248)		CTGAGCCTGCGGGAGGGGGAG	0.751													2	4	---	---	---	---					
PIK3R1	5295	broad.mit.edu	37	5	67589156	67589158	+	In_Frame_Del	DEL	AAA	AAA	-			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr5:67589156_67589158delAAA	ENST00000521381.1	+	10	1760_1762	c.1144_1146delAAA	c.(1144-1146)aaadel	p.K382del	PIK3R1_ENST00000396611.1_In_Frame_Del_p.K382del|PIK3R1_ENST00000521657.1_In_Frame_Del_p.K382del|PIK3R1_ENST00000320694.8_In_Frame_Del_p.K82del|PIK3R1_ENST00000274335.5_In_Frame_Del_p.K382del|PIK3R1_ENST00000523872.1_In_Frame_Del_p.K19del|PIK3R1_ENST00000336483.5_In_Frame_Del_p.K112del	NM_181523.2	NP_852664.1	P27986	P85A_HUMAN	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	382	SH2 1.				epidermal growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|growth hormone receptor signaling pathway|insulin receptor signaling pathway|insulin-like growth factor receptor signaling pathway|interspecies interaction between organisms|leukocyte migration|nerve growth factor receptor signaling pathway|phosphatidylinositol 3-kinase cascade|phosphatidylinositol phosphorylation|phosphatidylinositol-mediated signaling|platelet activation|positive regulation of establishment of protein localization in plasma membrane|positive regulation of glucose import|T cell costimulation|T cell receptor signaling pathway	1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex	1-phosphatidylinositol binding|ErbB-3 class receptor binding|insulin binding|insulin receptor binding|insulin receptor substrate binding|insulin-like growth factor receptor binding|phosphatidylinositol 3-kinase regulator activity|protein phosphatase binding	p.0?(1)|p.?(1)		breast(12)|central_nervous_system(31)|cervix(1)|endometrium(68)|haematopoietic_and_lymphoid_tissue(5)|kidney(1)|large_intestine(32)|lung(10)|ovary(9)|pancreas(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(3)|urinary_tract(2)	178		Lung NSC(167;1.99e-05)|Prostate(74;0.00308)|Ovarian(174;0.00473)|Colorectal(97;0.0176)		OV - Ovarian serous cystadenocarcinoma(47;3.76e-51)|Lung(70;0.0211)	Isoproterenol(DB01064)	CAAATTAATCAAAATATTTCATC	0.320			"""Mis, F, O"""		"""gliobastoma, ovarian, colorectal"""					TCGA GBM(4;<1E-08)			32	84	---	---	---	---					
SMAP1	60682	broad.mit.edu	37	6	71508370	71508370	+	Frame_Shift_Del	DEL	A	A	-			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr6:71508370delA	ENST00000370455.3	+	6	754	c.506delA	c.(505-507)gaafs	p.E169fs	SMAP1_ENST00000316999.5_Frame_Shift_Del_p.E142fs|SMAP1_ENST00000370452.3_Frame_Shift_Del_p.E142fs	NM_001044305.1|NM_001281440.1	NP_001037770.1|NP_001268369.1	Q8IYB5	SMAP1_HUMAN	small ArfGAP 1	169					regulation of ARF GTPase activity	plasma membrane	ARF GTPase activator activity|zinc ion binding	p.K145fs*48(1)		breast(3)|central_nervous_system(1)|endometrium(1)|large_intestine(2)|lung(6)|prostate(1)|urinary_tract(1)	15						aaagaaaaggaaaaaaaaaag	0.289													2	4	---	---	---	---					
TRAV12-2	28673	broad.mit.edu	37	14	22356275	22356276	+	RNA	INS	-	-	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr14:22356275_22356276insT	ENST00000390437.2	+	0	154																											TAGAAGCATGATTTTTTTTCTA	0.396													5	8	---	---	---	---					
PDXDC2P	283970	broad.mit.edu	37	16	70066043	70066043	+	RNA	DEL	A	A	-			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr16:70066043delA	ENST00000531894.1	-	0	751					NR_003610.1																						AGCCAAGCCGAAAAAAAAAAA	0.289													3	6	---	---	---	---					
GSE1	23199	broad.mit.edu	37	16	85682289	85682290	+	Frame_Shift_Ins	INS	-	-	C			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr16:85682289_85682290insC	ENST00000253458.7	+	3	534_535	c.358_359insC	c.(358-360)accfs	p.T120fs	GSE1_ENST00000393243.1_Frame_Shift_Ins_p.T47fs|GSE1_ENST00000405402.2_Frame_Shift_Ins_p.T16fs	NM_014615.2	NP_055430.1			Gse1 coiled-coil protein									p.V123fs*2(1)									CGTGCCCAGCACCCCCCCCGTG	0.688													8	79	---	---	---	---					
TGIF1	7050	broad.mit.edu	37	18	3452222	3452223	+	Frame_Shift_Del	DEL	CT	CT	-	rs11571510	by1000genomes	TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr18:3452222_3452223delCT	ENST00000330513.5	+	1	548_549	c.245_246delCT	c.(244-246)cctfs	p.P85fs	TGIF1_ENST00000405385.3_Intron|TGIF1_ENST00000551402.1_Intron|TGIF1_ENST00000407501.2_Intron|TGIF1_ENST00000548489.2_Intron|TGIF1_ENST00000343820.5_Intron|TGIF1_ENST00000345133.5_Intron|TGIF1_ENST00000401449.1_Intron|TGIF1_ENST00000551541.1_Intron|TGIF1_ENST00000577543.1_Intron	NM_170695.2	NP_733796.2	Q15583	TGIF1_HUMAN	TGFB-induced factor homeobox 1	85					negative regulation of transcription from RNA polymerase II promoter	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription corepressor activity	p.P83fs*51(1)		cervix(1)|endometrium(3)|large_intestine(4)|lung(2)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)	13	Esophageal squamous(4;0.0859)	Colorectal(8;0.0104)				TGCGCCCCCCCTCCTCCACCGG	0.762													6	13	---	---	---	---					
HMGXB4	10042	broad.mit.edu	37	22	35659135	35659136	+	Frame_Shift_Ins	INS	-	-	A	rs79846609		TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr22:35659135_35659136insA	ENST00000216106.5	+	3	224_225	c.96_97insA	c.(97-99)aaafs	p.K33fs	HMGXB4_ENST00000444518.2_5'UTR	NM_001003681.2	NP_001003681.1	Q9UGU5	HMGX4_HUMAN	HMG box domain containing 4	33					endosome to lysosome transport|negative regulation of Wnt receptor signaling pathway|Wnt receptor signaling pathway	NURF complex	DNA binding			breast(1)|endometrium(1)|large_intestine(6)|liver(1)|lung(4)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	19						GCCAACGAGAGAAAAAACGTTC	0.401													14	50	---	---	---	---					
DNAJB7	150353	broad.mit.edu	37	22	41257114	41257115	+	Frame_Shift_Ins	INS	-	-	T			TCGA-HT-A74K-01A-11D-A32B-08	TCGA-HT-A74K-10A-01D-A329-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	8f448f47-6b2f-403e-a474-bb14061167ad	808487c7-959f-429c-a322-da3d1f6c07c8	g.chr22:41257114_41257115insT	ENST00000307221.4	-	1	1015_1016	c.884_885insA	c.(883-885)aagfs	p.K295fs	XPNPEP3_ENST00000357137.4_Intron|XPNPEP3_ENST00000541156.1_Intron|XPNPEP3_ENST00000482652.1_Intron|XPNPEP3_ENST00000414396.1_Intron	NM_145174.1	NP_660157.1	Q7Z6W7	DNJB7_HUMAN	DnaJ (Hsp40) homolog, subfamily B, member 7	295	Poly-Lys.				protein folding		heat shock protein binding|unfolded protein binding			breast(2)|endometrium(2)|large_intestine(1)|lung(3)|ovary(1)|upper_aerodigestive_tract(1)	10						CTTTACGCTTCTTTTTTTTCCT	0.381													29	85	---	---	---	---					
